POMC gene expression in mouse and hamster melanoma cells

Academic Article

Abstract

  • Expression of mRNA hybridizable to murine POMC cDNA, and immunoreactivity specific for POMC derived peptide, β-endorphin, are reported for the first time in one murine and two hamster melanoma lines. The apparent sizes of POMC mRNA transcript were 3.5, 1.5 and 1 kb. It is suggested that POMC gene expression may be involved in the autoregulation of the melanoma phenotype at the cellular and tissue levels. © 1991.
  • Digital Object Identifier (doi)

    Author List

  • Slominski A
  • Start Page

  • 165
  • End Page

  • 168
  • Volume

  • 291
  • Issue

  • 2