Skin steroidogenesis in health and disease

Academic Article


  • © 2016, Springer Science+Business Media New York. The skin is an important extra-gonadal steroidogenic organ, capable of metabolizing various hormones from their precursors, as well as of synthesizing de novo a broad palette of sex steroids and glucocorticoids from cholesterol. In this manuscript, we review the major steroidogenic properties of human skin and we suggest steroidogenesis’ impairment as a cardinal factor for various pathological conditions such as acne, rosacea, atopic dermatitis, and androgenic alopecia.
  • Digital Object Identifier (doi)

    Author List

  • Nikolakis G; Stratakis CA; Kanaki T; Slominski A; Zouboulis CC
  • Start Page

  • 247
  • End Page

  • 258
  • Volume

  • 17
  • Issue

  • 3