© 2012 Springer Science+Business Media New York. All rights are reserved. Heart failure (HF) is common and is associated with poor prognosis. Chronic kidney disease (CKD) is common in HF, and shares many risk factors with HF such as age, hypertension, diabetes, and coronary artery disease. Findings from large HF registries suggest that over half of all HF patients may have CKD. The concomitant presence of CKD is associated with increased morbidity and mortality in HF; yet, it is also associated with underutilization of evidence-based HF therapy that may reduce morbidity and mortality. Understanding the epidemiology and outcomes of CKD in HF is essential to ensure proper management of these patients.