Neonatal cord serum alpha 2-macroglobulin and fetal size at birth

Academic Article


  • Serum concentrations of alpha-2-macroglobulin (α2M) were measured in cord blood from neonates born in Alabama, USA and in Guatemala. Results indicate an inverse relationship between cord serum α2M concentrations and birth weight of newborns in both locations. Infants with lower birth weight had higher cord serum α2M concentrations as compared to those with higher birth weight. The results of the present study using cord serum are similar to those in our previous reports indicating an inverse relationship between maternal serum α2M concentrations and birth weight. This distinctive and reproducible association between α2M concentrations and fetal size in maternal as well as cord blood samples warrants further investigations to determine the mechanism of this relationship. © 1993.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Cliver SP; Goldenberg RL; Neel NR; Tamura T; Johnston KE; Hoffman HJ
  • Start Page

  • 201
  • End Page

  • 206
  • Volume

  • 33
  • Issue

  • 3