Avirulence of LT2 strains of Salmonella typhimurium results from a defective rpoS gene

Academic Article


  • In order to identify the genetic basis for the attenuation of Salmonella typhimurium LT2 strains, experiments were performed to identify a gene(s) which restores virulence to an avirulent LT2 strain. These and further experiments confirmed that an rpoS mutation is the sole determinant of the attenuation of S. typhimurium LT2.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Swords WE; Cannon BM; Benjamin WH
  • Start Page

  • 2451
  • End Page

  • 2453
  • Volume

  • 65
  • Issue

  • 6