HLA studies in brucellar spondylitis

Academic Article


  • Among the clinical manifestations of brucellosis, arthritis may occur in over one-third of the patients. Different articular syndromes have been well recognized: some are definitely infectious in nature, whereas others appear to be reactive. The possibility that B27 and B7-CREG antigens could predispose to the occurrence of brucellar spondylitis was investigated in 14 mestizo Peruvian patients. No association was found. Since there is a low frequency of B27 and B7-CREG in the control population, the possibility that a "native" antigen could be the predisposing one remains to be elucidated. © 1985 Springer-Verlag.
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    Digital Object Identifier (doi)

    Author List

  • Alarcón GS; Gotuzzo E; Hinostroza SA; Carrillo C; Bocanegra TS; Espinoza LR
  • Start Page

  • 312
  • End Page

  • 314
  • Volume

  • 4
  • Issue

  • 3