Cryptococcal empyema: Case report and review

Academic Article


  • A 28-year-old male infected with the human immunodeficiency virus (HIV) developed a pleural empyema caused by Cryptococcus neoformans. He responded well to chest-tube drainage and antifungal therapy; he received fluconazole as maintenance therapy for 1 year and has not relapsed. We reviewed the English-language literature on cryptococcal pleural effusions in patients with and without AIDS. Only three other cases of empyema, one of them in an HIV-infected patient, have been reported. A pleural-fluid cryptococcal antigen test was diagnostic in our case and should be included in the diagnostic evaluation of unexplained pleural empyema/effusion in immunocompromised patients. © 1995 by The University of Chicago. All rights reserved.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Mulanovich VE; Dismukes WE; Markowitz N
  • Start Page

  • 1396
  • End Page

  • 1398
  • Volume

  • 20
  • Issue

  • 5