Linking metastasis suppression with metastamiR regulation

Academic Article

Abstract

  • Cancer metastasis requires the coordinate expression of multiple genes during every step of the metastatic cascade. Molecules that regulate these genetic programs have the potential to impact metastasis at multiple levels. Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis by inhibiting multiple steps in the cascade through regulation of many protein-encoding, metastasis-associated genes as well as metastasis-regulatory microRNA, termed metastamiR. In this Feature, we will highlight connections between BRMS1 biology and regulation of metastamiR.
  • Published In

  • Cell Cycle  Journal
  • Digital Object Identifier (doi)

    Author List

  • Edmonds MD; Hurst DR; Welch DR
  • Start Page

  • 2673
  • End Page

  • 2675
  • Volume

  • 8
  • Issue

  • 17