The complement component C4 in black Americans with Type 1 (insulin-dependent) diabetes mellitus

Academic Article

Abstract

  • The complement component C4 variants C4A4, C4B 4 and C4B QO were found to be significantly increased in 64 black patients with Type 1 (insulin-dependent) diabetes compared with 169 black control subjects, yielding relative risks of 3.3, 2.9 and 3.4, respectively. The increased frequencies of C4B 4 and C4B QO in black Type 1 diabetic patients are similar to those found in Caucasoid Type 1 diabetic patients. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of genes from whites. © 1984 Springer-Verlag.
  • Published In

  • Diabetologia  Journal
  • Digital Object Identifier (doi)

    Author List

  • Budowle B; Roseman JM; Go RCP; Barger BO; Acton RT
  • Start Page

  • 166
  • End Page

  • 168
  • Volume

  • 26
  • Issue

  • 2