The incidence of stroke in diabetic patients is high. Remember, though, that hypoglycemia, hyperosmolar nonketotic coma, or a postepileptic state may mimic stroke and should be ruled out. Rehydration is essential in diabetic stroke patients, since hyperglycemia can lead to dehydration. Control blood glucose levels to 120 mg/dL or below; higher levels are associated with greater morbidity and mortality. Correct hypertension slowly to avoid further cerebral ischemia. Warfarin, given 3 to 5 days after an ischemic stroke and for at least 3 months, may benefit many patients. Stroke prevention includes hypertension control and antiplatelet therapy (in patients not receiving anticoagulants).