Effect of injection rate of contrast medium on pancreatic and hepatic helical CT.

Academic Article

Abstract

  • PURPOSE: To assess the effect of the injection rate of contrast medium on pancreatic and hepatic enhancement at abdominal helical computed tomography (CT). MATERIALS AND METHODS: Sixty-four contrast medium-enhanced abdominal helical CT scans (64 adult patients) were obtained with 150 mL of contrast medium. The injection rate was 2.5 mL/sec for the first 32 scans and 5.0 mL/sec for the remaining 32. Scans were obtained at 5-sec intervals, with an intermediate 8-sec breathing interval. Hepatic and pancreatic enhancement levels were measured and averaged, and time-attenuation curves were plotted for both groups. Differences in weight, age, time to peak pancreatic and hepatic enhancement, and peak enhancement were assessed with the Student t test. RESULTS: Both peak enhancement and time to peak enhancement were significantly different between the two injection rates (P < or = .002), with faster, more intense hepatic and pancreatic enhancement at the higher rate. At 2.5 mL/sec, the pancreas reached a peak attenuation level of 65 HU at 69 sec, and the liver reached a peak of 58 HU at 87 sec. At 5.0 mL/sec, the pancreas reached a peak attenuation of 84 HU at 43 sec, and the liver reached a peak of 75 HU at 63 sec.
  • Published In

  • Radiology  Journal
  • Keywords

  • Adult, Aged, Aged, 80 and over, Contrast Media, Diatrizoate Meglumine, Female, Humans, Injections, Intravenous, Iohexol, Liver, Male, Middle Aged, Pancreas, Prospective Studies, Tomography, X-Ray Computed
  • Digital Object Identifier (doi)

    Author List

  • Tublin ME; Tessler FN; Cheng SL; Peters TL; McGovern PC
  • Start Page

  • 97
  • End Page

  • 101
  • Volume

  • 210
  • Issue

  • 1