My laboratory pioneered Cardiac and Vascular Tissue Chip Models (BCTM and VPPM) which represent the state-of-the art for culture of cardiac and vascular cells in-vitro. As a Biomedical Engineer, I have extensive experience in the areas of tissue engineering and fluid mechanics, which has enabled me to design and construct systems for culture of cells in environments that mimic the complex hemodynamic stresses in cardiac and vascular tissues. Recently, we have expanded our work to build tissue chip models of the Kidney focusing on drug induced nephrotoxicity. My laboratory has been funded by major federal funding agencies including NIH, NSF, DoD and NASA and private foundations like the Alabama Institute of Medicine, Kentucky Science and Technology Foundation and the Wallace H. Coulter Foundation. I have successfully administered projects, collaborated with other researchers, and produced several peer-reviewed publications from each project.