Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Cellular antioxidant mechanisms control immunoglobulin light chain-mediated proximal tubule injuryFree Radical Biology and Medicine.  171:80-90. 2021
2021 UAB-UCSD o'brien center for acute kidney injury research 2021
2021 Renoprotective effect of Stat1 deletion in murine aristolochic acid nephropathy 2021
2021 Restoration of afferent arteriolar autoregulatory behavior in ischemia-reperfusion injury in rat kidneys 2021
2020 Clinicopathologic predictors of renal outcomes in light chain cast nephropathy: A multicenter retrospective studyBlood.  135:1833-1846. 2020
2020 Gene knockout of the Na+-glucose cotransporter SGLT2 in a murine model of acute kidney injury induced by ischemia-reperfusion 2020
2020 Practical applications of studies on the TSH receptor and TSH receptor autoantibodiesEndocrine.  68:261-264. 2020
2020 Serum free light chain level at diagnosis in myeloma cast nephropathy—a multicentre studyBlood Cancer Journal.  10. 2020
2019 Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70TM a human monoclonal autoantibody to the TSH receptor with TSH antagonist activityAutoimmunity Highlights.  10. 2019
2019 Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertensionFree Radical Biology and Medicine.  134:343-349. 2019
2016 Family history of hematologic malignancies and risk of multiple myeloma: differences by race and clinical featuresCancer Causes and Control.  27:81-91. 2016
2016 Paraprotein-related kidney disease: Kidney injury from paraproteins—What determines the site of injury?Clinical Journal of the American Society of Nephrology.  11:2288-2294. 2016
2015 Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake 2015
2015 ReplyAmerican Journal of Cardiology.  115:156. 2015
2014 Distinct populations of label-retaining cells in the adult kidney are defined temporally and exhibit divergent regional distributions 2014
2014 Nitric oxide and carbon monoxide antagonize TGF-β through ligandindependent internalization of TβR1/ALK5 2014
2014 Sodium and potassium regulate endothelial phospholipase C-γ and Bmx 2014
2014 Spironolactone use and higher hospital readmission for medicare beneficiaries with heart failure, left ventricular ejection fraction <45%, and estimated glomerular filtration rate <45 ml/min/1.73 m2American Journal of Cardiology.  114:79-82. 2014
2014 Community mobility among older adults with reduced kidney function: A study of life-spaceAmerican Journal of Kidney Diseases.  63:429-436. 2014
2013 Beware the low HDAC11: Males at risk for ischemic kidney injury 2013
2013 Hypertensive Nephrosclerosis: Not enough of a good thing? 2013
2013 Renin-angiotensin inhibition in diastolic heart failure and chronic kidney diseaseAmerican Journal of Medicine.  126:150-161. 2013
2013 KDOQI US commentary on the 2012 KDIGO clinical practice guideline for management of blood pressure in CKDAmerican Journal of Kidney Diseases.  62:201-213. 2013
2012 Evolving Strategies in the Diagnosis, Treatment, and Monitoring of Myeloma KidneyAdvances in Renal Replacement Therapy.  19:279-281. 2012
2012 In vivo effects of a human thyroid-stimulating monoclonal autoantibody (M22) and a human thyroid-blocking autoantibody (K1-70)Autoimmunity Highlights.  3:19-25. 2012
2012 Renin-angiotensin inhibition in systolic heart failure and chronic kidney diseaseAmerican Journal of Medicine.  125:399-410. 2012
2012 Enabling Innovative Translational Research in Acute Kidney InjuryClinical and Translational Science.  5:93-101. 2012
2012 Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain-mediated apoptosisAmerican Journal of Pathology.  180:41-47. 2012
2011 A propensity-matched study of the comparative effectiveness of angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors in heart failure patients age <65 yearsAmerican Journal of Cardiology.  108:1443-1448. 2011
2011 Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) studyAmerican Journal of Clinical Nutrition.  94:1071-1078. 2011
2011 Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: Potential mechanistic insights from epidemiological dataEuropean Heart Journal.  32:712-720. 2011
2011 Immunoglobulin light chains activate nuclear factor-κB in renal epithelial cells through a Src-dependent mechanismBlood.  117:1301-1307. 2011
2011 Light chain-mediated tubulopathiesContributions to Nephrology.  169:262-269. 2011
2011 Mechanisms and consequences of salt sensitivity and dietary salt intakeCurrent Opinion in Nephrology and Hypertension.  20:37-43. 2011
2011 Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1 2011
2011 Relationship between stage of kidney disease and incident heart failure in older adultsAmerican Journal of Nephrology.  34:135-141. 2011
2010 Monoclonal autoantibodies to the TSH receptor, one with stimulating activity and one with blocking activity, obtained from the same blood sampleClinical Endocrinology.  73:404-412. 2010
2010 Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease findings from propensity-matched studiesCirculation: Heart Failure.  3:253-260. 2010
2009 Vascular consequences of dietary salt intake 2009
2009 Bortezomib successfully reduces monoclonal serum free light chain levels in a patient with recurrent myeloma and cast nephropathy in the renal transplant.Clinical Transplants.  439-441. 2009
2008 Mechanism of dietary salt-mediated increase in intravascular production of TGF-β1 2008
2008 Contribution of intrarenal cells to cellular repair after acute kidney injury: Subcapsular implantation technique 2008
2007 Detection of early changes in renal function using 99mTc-MAG3 imaging in a murine model of ischemia-reperfusion injury 2007
2007 Chronic Kidney Disease Associated Mortality in Diastolic Versus Systolic Heart Failure: A Propensity Matched Study†The Digitalis Investigation Group study was conducted and supported by the National Heart, Lung, and Blood Institute in collaboration with the Digitalis Investigation Group Investigators ...American Journal of Cardiology.  99:393-398. 2007
2006 A new twist in myeloma treatmentBlood.  107:413-414. 2006
2006 Effect of salt intake on progression of chronic kidney diseaseCurrent Opinion in Nephrology and Hypertension.  15:54-60. 2006
2005 Enhanced expression of EGF receptor in a model of salt-sensitive hypertension 2005
2005 Management of paraproteinemic renal diseaseCurrent Opinion in Nephrology and Hypertension.  14:97-103. 2005
2005 Mechanism of hypertensive nephropathy in the Dahl/Rapp rat: A primary disorder of vascular smooth muscle 2005
2003 Accelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthaseBiochemical Journal.  376:789-794. 2003
2003 The interrelationship between TGF-beta1 and nitric oxide is altered in salt-sensitive hypertension. 2003
2003 Mitochondrial targets of oxidative stress during renal ischemia/reperfusionArchives of Biochemistry and Biophysics.  412:27-33. 2003
2003 The interrelationship between TGF-β1 and nitric oxide is altered in salt-sensitive hypertension 2003
2002 Activation of the Fas/Fas ligand pathway in hypertensive renal disease in Dahl/Rapp ratsBMC Nephrology.  3:1-9. 2002
2001 Mitochondrial tyrosine nitration precedes chronic allograft nephropathyFree Radical Biology and Medicine.  31:1603-1608. 2001
2001 Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stabilityCirculation Research.  89:317-322. 2001
2001 Mapping the binding domain of immunoglobulin light chains for Tamm-Horsfall proteinAmerican Journal of Pathology.  158:1859-1866. 2001
2001 The distribution and regulation of integrin-linked kinase in normal and diabetic kidneysAmerican Journal of Pathology.  159:1735-1742. 2001
1999 Dietary salt increases endothelial nitric oxide synthase and TGF-beta1 in rat aortic endothelium.American Journal of Physiology.  277:H1293-H1298. 1999
1999 Dietary salt increases endothelial nitric oxide synthase and TGF-β1 in rat aortic endothelium 1999
1998 Dietary salt enhances glomerular endothelial nitric oxide synthase through TGF-beta1.American Journal of Physiology.  275:F18-F24. 1998
1998 Dietary salt modulates renal production of transforming growth factor-beta in rats.American Journal of Physiology.  274:F635-F641. 1998
1998 Dietary salt enhances glomerular endothelial nitric oxide synthase through TGF-β1 1998
1998 Dietary salt modulates renal production of transforming growth factor-β in rats 1998
1998 In vitro modulation of AL-amyloid formation by Human Mesangial Cells exposed to amyloidogenic Light Chains 1998
1997 Estrogen restores endothelial cell function in an experimental model of vascular injuryCirculation.  96:1624-1630. 1997
1997 Immunoglobulin light chain alters mesangial cell calcium homeostasis.American Journal of Physiology.  272:F319-F324. 1997
1997 Immunoglobulin light chain alters mesangial cell calcium homeostasis 1997
1996 Salt-sensitive hypertension: Lessons from animal modelsAmerican Journal of Kidney Diseases.  28:775-782. 1996
1995 L-arginine and arginine analogs in progressive penal failureBlood Purification.  13:219-227. 1995
1995 Pathogenesis of glomerulosclerosis in light chain deposition disease: Role for transforming growth factor-βAmerican Journal of Pathology.  147:375-385. 1995
1993 Potential role of colchicine in the prevention of cast nephropathy from Bence Jones proteins.Contributions to Nephrology.  101:104-108. 1993
1993 Renal involvement in plasma cell dyscrasias.Current Opinion in Nephrology and Hypertension.  2:246-252. 1993
1990 Altered loop segment function is the initial event in precipitation of low-molecular-weight proteins in the rat nephron.Contributions to Nephrology.  83:100-103. 1990
1988 Differential toxicity of human Bence-Jones proteins in the rat proximal convoluted tubule in vivo.Contributions to Nephrology.  68:198-202. 1988
1985 Hemodialysis Without AnticoagulationAmerican Journal of Kidney Diseases.  5:32-35. 1985
1978 The antiarrhythmic action of amitriptyline on arrhythmias associated with myocardial infarction in dogs 1978

Book

Year Title Altmetric
2007 Paraproteinemic renal diseases that involve the tubulo-interstitium.  Ed. 153.  2007

Chapter

Year Title Altmetric
2013 Dysproteinemias and amyloidosis.  235-243. 2013
2008 Myeloma and Secondary Involvement of the Kidney in Dysproteinemias.  461-468. 2008
2008 Pathogenesis of paraproteinemic renal disease.  435-440. 2008
2007 The influence of dietary salt intake on endothelial cell function.  1287-1293. 2007

Investigator On

  • Center for Clinical and Translational Science (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS
  • Ferritin Mediates Epithelial Cell-Macrophage Cross Talk in Acute Kidney Injury  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Interdisciplinary Training In Kidney-Related Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Interdisciplinary Training in Kidney-Related Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Kidney Undergraduate Research Experience (KURE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • PRedOctoral Phd and MD Research Training In TEams (PROmoTE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • PRedoctoral Interdisciplinary Training in Renal Physiology and MEdIcIne (PRIME)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • The Endoplasmic Reticulum Stress Protein Calreticulin in Diabetic Chronic Kidney Disease  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY
  • Training Program in Cardiovascular Pathophysiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • UAB Center for Clinical and Translational Science (CCTS) (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Center for Acute Kidney Injury Research - Admin Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Core Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB-UCSD O'Brien Core Center for Acute Kidney Injury Research - Administrative Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • UAB/UCSD O'Brien Core Center for Acute Kidney Injury Research - Administrative Core  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Education And Training

  • UAB Hospital, Internship
  • UAB Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine, University of South Alabama 1979
  • Full Name

  • Paul Sanders