Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Ciclopirox olamine induces ferritinophagy and reduces cyst burden in polycystic kidney diseaseJCI insight.  6. 2021
2020 Iron Homeostasis and Ferritin in Sepsis-Associated Kidney Injury 2020
2020 Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrierActa Neuropathologica.  140:549-567. 2020
2020 Ferritins in Kidney DiseaseSeminars in Nephrology.  40:160-172. 2020
2019 Dynamic signature of lymphangiogenesis during acute kidney injury and chronic kidney diseaseLaboratory Investigation.  99:1376-1388. 2019
2019 Resident macrophages reprogram toward a developmental state after acute kidney injuryJCI insight.  4. 2019
2019 Ferritin light chain confers protection against sepsis-induced inflammation and organ injuryFrontiers in Immunology.  10. 2019
2019 Renal control of disease tolerance to malaria 2019
2018 Myeloid HO-1 modulates macrophage polarization and protects against ischemia-reperfusion injuryJCI insight.  3. 2018
2018 Heme oxygenase-1 mitigates Ferroptosis in renal proximal tubule cells 2018
2017 Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction HealingScientific Reports.  7. 2017
2017 Unique sex- and age-dependent effects in protective pathways in acute kidney injury 2017
2017 Heme Oxygenase 1 as a Therapeutic Target in Acute Kidney InjuryAmerican Journal of Kidney Diseases.  69:531-545. 2017
2016 Early lipid changes in acute kidney injury using SWATH lipidomics coupled with MALDI tissue imaging 2016
2016 Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury 2016
2016 Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung InjuryAntioxidants and Redox Signaling.  24:99-112. 2016
2015 Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injuryHuman Molecular Genetics.  24:4078-4093. 2015
2015 Macrophage and epithelial cell H-ferritin expression regulates renal inflammationKidney International.  88:95-108. 2015
2015 Heme oxygenase-1 protects Corexit 9500ainduced respiratory epithelial injury across speciesPLoS ONE.  10. 2015
2015 Heme oxygenase-1 regulates myeloid cell trafficking in AKIJournal of the American Society of Nephrology.  26:2139-2151. 2015
2013 Proximal tubule h-ferritin mediates iron trafficking in acute kidney injuryJournal of Clinical Investigation.  123:4423-4434. 2013
2013 Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinaseLaboratory Investigation.  93:868-879. 2013
2013 Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells 2013
2013 Pleural mesothelial cell differentiation and invasion in fibrogenic lung injuryAmerican Journal of Pathology.  182:1239-1247. 2013
2013 Mitochondria and reactive oxygen species: Physiology and pathophysiologyInternational Journal of Molecular Sciences.  14:6306-6344. 2013
2013 Adaptive responses to tissue injury: role of heme oxygenase-1. 2013
2012 In vivo regulation of the heme oxygenase-1 gene in humanized transgenic miceKidney International.  82:278-291. 2012
2012 Kidney injury accelerates cystogenesis via pathways modulated by heme oxygenase and complementJournal of the American Society of Nephrology.  23:1161-1171. 2012
2011 Urine albumin as a biomarker in acute kidney injury 2011
2010 Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cellsJournal of Biological Chemistry.  285:16476-16486. 2010
2010 Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injuryJournal of the American Society of Nephrology.  21:1702-1712. 2010
2009 Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injuryCirculation Research.  105:965-972. 2009
2009 The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cellsBiochemical Journal.  419:427-436. 2009
2009 Carbon monoxide rescues heme oxygenase-1-deficient mice from arterial thrombosis in allogeneic aortic transplantationAmerican Journal of Pathology.  175:422-429. 2009
2009 Neutrophils in acute kidney injury: Not neutral any moreKidney International.  75:674-676. 2009
2008 Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulonJournal of Biological Chemistry.  283:18032-18039. 2008
2008 Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen-presenting cellsAmerican Journal of Pathology.  173:154-160. 2008
2007 Subclinical kidney injury incites endotoxin hyperresponsiveness 2007
2007 Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosisCirculation Research.  100:1703-1711. 2007
2005 A framework to sub-type HLA supertypes.Frontiers in Bioscience.  10:879-886. 2005

Education And Training

  • Doctor of Philosophy in Cell / Cellular Biology and Histology, University of Alabama at Birmingham 2010
  • Bachelor's Level Degree in Physiology, Pathology and Related Sciences, 2005
  • Full Name

  • Subhashini Bolisetty