Selected Publications

Academic Article

Year Title Altmetric
2022 Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor AFrontiers in Cell and Developmental Biology.  10. 2022
2021 NAP1L1 and NAP1L4 binding to hypervariable domain of Chikungunya Virus nsP3 protein is bivalent and requires phosphorylationJournal of Virology.  95. 2021
2021 Multilayered Ordered Protein Arrays Self-Assembled from a Mixed Population of Virus-like ParticlesACS Nano2021
2020 The connector domain of vesicular stomatitis virus large protein interacts with the viral phosphoproteinJournal of Virology.  94. 2020
2019 Structural and biophysical characterizations of HIV-1 matrix trimer binding to lipid nanodiscs shed light on virus assemblyJournal of Biological Chemistry.  294:18600-18612. 2019
2019 Editorial overview: Virus structure and expressionCurrent Opinion in Virology.  36:iii-v. 2019
2018 Phage assembly and the special role of the portal proteinCurrent Opinion in Virology.  31:66-73. 2018
2018 Modular Self-Assembly of Protein Cage Lattices for Multistep CatalysisACS Nano.  12:942-953. 2018
2017 Pathways for gold nucleation and growth over protein cagesLangmuir: the ACS journal of surfaces and colloids.  33:5925-5931. 2017
2017 Targeted mutagenesis of the P22 portal protein reveals the mechanism of signal transmission during DNA packagingVirology.  505:127-138. 2017
2017 Self-assembly of P22 protein cages with polyamidoamine dendrimer and inorganic nanoparticlesJournal of Materials Research.  32:465-472. 2017
2017 φX174 procapsid assembly: Effects of an inhibitory external scaffolding protein and resistant coat proteins in vitroJournal of Virology.  91. 2017
2016 Poxvirus uracil-DNA glycosylase—An unusual member of the family I uracil-DNA glycosylasesProtein Science.  25:2113-2131. 2016
2016 Detecting asymmetry in the presence of symmetry with maximum likelihood threedimensional reconstructions of viruses from electron microscope imagesIET Image Processing.  10:624-629. 2016
2016 Follow the Yellow Brick Road: A Paradigm Shift in Virus AssemblyJournal of Molecular Biology.  428:416-418. 2016
2016 Identification of the calmodulin-binding domains of Fas death receptorPLoS One.  11. 2016
2016 Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding siteNature Communications.  7. 2016
2016 Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virionsJournal of Biological Chemistry.  291:215-226. 2016
2015 A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugationPLoS One.  10. 2015
2015 Higher Order Assembly of Virus-like Particles (VLPs) Mediated by Multi-valent Protein LinkersSmall.  11:1562-1570. 2015
2015 P22 virus-like particles constructed Au/CdS plasmonic photocatalytic nanostructures for enhanced photoactivityChemical Communications.  51:1062-1065. 2015
2015 Selective biotemplated synthesis of TiO2 inside a protein cageBiomacromolecules.  16:214-218. 2015
2015 Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycleBBA: Proteins and Proteomics.  1854:341-348. 2015
2014 The role of the coat protein A-domain in P22 bacteriophage maturationViruses.  6:2708-2722. 2014
2014 Charge detection mass spectrometry of bacteriophage P22 procapsid distributions above 20 MDaRapid Communications in Mass Spectrometry.  28:483-488. 2014
2014 Formation mechanism of chalcogenide nanocrystals confined inside genetically engineered virus-like particlesScientific Reports.  4. 2014
2014 Higher-order structure of the rous sarcoma virus SP assembly domainJournal of Virology.  88:5617-5629. 2014
2013 Location of the bacteriophage P22 coat protein C-terminus provides opportunities for the design of capsid-based materialsBiomacromolecules.  14:2989-2995. 2013
2013 φ29 Scaffolding and connector structure-function relationship studied by trans-complementationVirology.  444:355-362. 2013
2013 Stabilizing viral nano-reactors for nerve-agent degradationBiomaterials Science.  1:881-886. 2013
2013 Structural and functional characterization of the mumps virus phosphoproteinJournal of Virology.  87:7558-7568. 2013
2013 Gap2 promotes the formation of a stable protein complex required for mature Fap1 biogenesisJournal of Bacteriology.  195:2166-2176. 2013
2013 Engineering nanocages with polyglutamate domains for coupling to hydroxyapatite biomaterials and allograft boneBiomaterials.  34:2455-2462. 2013
2013 Directed self-assembly of CdS quantum dots on bacteriophage P22 coat protein templatesNanotechnology.  24. 2013
2013 P22 viral capsids as nanocomposite high-relaxivity MRI contrast agentsMolecular Pharmaceutics.  10:11-17. 2013
2012 Coconfinement of fluorescent proteins: Spatially enforced communication of GFP and mCherry encapsulated within the P22 capsidBiomacromolecules.  13:3902-3907. 2012
2012 Virus-like particle nanoreactors: Programmed encapsulation of the thermostable CelB glycosidase inside the P22 capsidSoft Matter.  8:10158-10166. 2012
2012 Use of the interior cavity of the P22 capsid for site-specific initiation of atom-transfer radical polymerization with high-density cargo loadingNature Chemistry.  4:781-788. 2012
2012 Nanoreactors by programmed enzyme encapsulation inside the capsid of the bacteriophage P22ACS Nano.  6:5000-5009. 2012
2012 Building the machines: Scaffolding protein functions during bacteriophage morphogenesisAdvances in Experimental Medicine and Biology.  726:325-350. 2012
2012 Site-directed coordination chemistry with P22 virus-like particlesLangmuir: the ACS journal of surfaces and colloids.  28:1998-2006. 2012
2011 Materials design using genetically engineered proteinsJournal of Materials Chemistry.  21:18868-18876. 2011
2011 Genetically programmed in vivo packaging of protein cargo and its controlled release from bacteriophage P22Angewandte Chemie International Edition.  50:7425-7428. 2011
2011 A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assemblyJournal of Molecular Biology.  410:641-652. 2011
2011 New approaches for antiviral targeting of HIV assemblyJournal of Molecular Biology.  410:634-640. 2011
2011 Templated assembly of organic-inorganic materials using the core shell structure of the P22 bacteriophageChemical Communications.  47:6326-6328. 2011
2011 Erratum: Peering down the barrel of a bacteriophage portal: The genome packaging and release valve in P22 (Structure (2011) 18 (597-603))Structure.  19:748. 2011
2011 Peering down the barrel of a bacteriophage portal: The genome packaging and release valve in P22Structure.  19:496-502. 2011
2011 Three-dimensional structure of a viral genome-delivery portal vertexNature Structural and Molecular Biology.  18:597-603. 2011
2010 Fabrication of ordered nanostructures of sulfide nanocrystal assemblies over self-assembled genetically engineered P22 coat proteinJournal of the American Chemical Society.  132:17354-17357. 2010
2010 Hydrogen/Deuterium Exchange Analysis of HIV-1 Capsid Assembly and MaturationStructure.  18:1483-1491. 2010
2010 Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pHBiochemistry.  49:9551-9562. 2010
2010 Mind the gap: How some viruses infect their hostsViruses.  2:2536-2540. 2010
2010 Implementation of P22 viral capsids as nanoplatformsBiomacromolecules.  11:2804-2809. 2010
2010 Escherichia coli bacteria-templated synthesis of nanoporous cadmium sulfide hollow microrods for efficient photocatalytic hydrogen productionThe Journal of Physical Chemistry C: Energy Conversion and Storage, Optical and Electronic Devices, Interfaces, Nanomaterials, and Hard Matter.  114:2551-2559. 2010
2010 A docking model based on mass spectrometric and biochemical data describes phage packaging motor incorporationMolecular and Cellular Proteomics.  9:1764-1773. 2010
2010 Polymer-virus core-shell structures prepared via co-assembly and template synthesis methods 2010
2009 In vitro incorporation of the phage Phi29 connector complexVirology.  394:149-153. 2009
2009 Characterization of a mumps virus nucleocapsidlike particleJournal of Virology.  83:11402-11406. 2009
2009 Synthesis of biotin-tagged chemical cross-linkers and their applications for mass spectrometryRapid Communications in Mass Spectrometry.  23:1719-1726. 2009
2009 The P22 Tail Machine at Subnanometer Resolution Reveals the Architecture of an Infection ConduitStructure.  17:789-799. 2009
2008 Controlled assembly of bifunctional chimeric protein cages and composition analysis using noncovalent mass spectrometryJournal of the American Chemical Society.  130:16527-16529. 2008
2008 Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 ProcapsidJournal of Molecular Biology.  381:1395-1406. 2008
2008 Send for Reinforcements! Conserved Binding of Capsid Decoration ProteinsStructure.  16:1292-1293. 2008
2008 Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium ExchangeJournal of Molecular Biology.  381:772-784. 2008
2008 Hydrogen/deuterium exchange on protein solutions containing nucleic acids: Utility of protamine sulfateRapid Communications in Mass Spectrometry.  22:2423-2428. 2008
2008 Development of bacteriophage P22 a platform for molecular display: Genetic and chemical modifications of the procapsid exterior surfaceChemBioChem: a European journal of chemical biology.  9:514-518. 2008
2008 Incorporation of scaffolding protein gpO in bacteriophages P2 and P4Virology.  370:352-361. 2008
2007 Subunit Conformations and Assembly States of a DNA-translocating Motor: The Terminase of Bacteriophage P22Journal of Molecular Biology.  374:817-836. 2007
2007 An aggregation-prone intermediate species is present in the unfolding pathway of the monomeric portal protein of bacteriophage P22: Implications for portal assemblyBiochemistry.  46:7353-7364. 2007
2007 Molecular Dissection of Ø29 Scaffolding Protein Function in an in Vitro Assembly SystemJournal of Molecular Biology.  366:1161-1173. 2007
2007 Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assembliesJournal of Structural Biology.  157:371-383. 2007
2006 The structure of an infectious P22 virion shows the signal for headful DNA packagingScience.  312:1791-1795. 2006
2006 Dynamic motions of free and bound Ø29 scaffolding protein identified by hydrogen deuterium exchange mass spectrometryProtein Science.  15:731-743. 2006
2006 Identification of subunit-subunit interactions in bacteriophage P22 procapsids by chemical cross-linking and mass spectrometryJournal of Proteome Research.  5:370-377. 2006
2005 Kinetic and Mass Spectrometry-Based Investigation of Human Immunodeficiency Virus Type 1 Assembly and MaturationAdvances in virus research.  64:285-309. 2005
2005 Three-dimensional structure of the bacteriophage P22 tail machineThe EMBO Journal.  24:2087-2095. 2005
2005 In vitro assembly of bacteriophages: Folding, kinetic control and intermediatesJournal of Theoretical Medicine.  6:139. 2005
2005 Domain study of bacteriophage P22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchangeJournal of Molecular Biology.  347:935-948. 2005
2004 Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1 CABiochemistry.  43:10435-10441. 2004
2004 Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchangeNature Structural and Molecular Biology.  11:676-677. 2004
2004 High-sensitivity mass spectrometry for imaging subunit interactions: Hydrogen/deuterium exchangeCurrent Opinion in Structural Biology.  14:181-188. 2004
2003 Erratum: Identification of Novel Interactions in HIV-1 Capsid Protein Assembly by High-resolution Mass Spectrometry (Journal of Molecular Biology (2003) 325 (759-772))Journal of Molecular Biology.  334:1133. 2003
2003 Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutionsNature Structural and Molecular Biology.  10:131-135. 2003
2003 Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometryJournal of Molecular Biology.  325:759-772. 2003
2003 Mechanism of scaffolding-assisted viral assemblyAdvances in Protein Chemistry.  64:259-299. 2003
2003 Viral genome organizationAdvances in Protein Chemistry.  64:219-258. 2003
2002 Mapping of protein:protein contact surfaces by hydrogen/deuterium exchange, followed by on-line high-performance liquid chromatography-electrospray ionization fourier-transform ion-cyclotron-resonance mass analysisJournal of Chromatography A.  982:85-95. 2002
2002 Preliminary crystallographic analysis of the bacteriophage P22 portal proteinJournal of Structural Biology.  139:46-54. 2002
2002 A P22 scaffold protein mutation increases the robustness of head assembly in the presence of excess portal proteinJournal of Virology.  76:10245-10255. 2002
2002 Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitroJournal of Virology.  76:6900-6908. 2002
2002 DNA packaging: A new class of molecular motorsCurrent Biology.  12:R96-R98. 2002
2002 Bacteriophage p22 portal vertex formation in vivoJournal of Molecular Biology.  315:975-994. 2002
2001 Structure of bacteriophage P22 portal protein in relation to assembly: Investigation by Raman spectroscopyBiochemistry.  40:13583-13591. 2001
2001 Kinetic and calorimetric evidence for two distinct scaffolding protein binding populations within the bacteriophage P22 procapsidBiochemistry.  40:8962-8970. 2001
2001 Structural Transformations Accompanying the Assembly of Bacteriophage P22 Portal Protein Rings in VitroJournal of Biological Chemistry.  276:6779-6788. 2001
2001 Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsidsJournal of Molecular Biology.  306:389-396. 2001
2001 Characterization of subunit structural changes accompanying assembly of the bacteriophage P22 procapsidBiochemistry.  40:665-674. 2001
2000 Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virusJournal of Molecular Biology.  297:1195-1202. 2000
2000 Identification of additional coat-scaffolding interactions in a bacteriophage P22 mutant defective in maturationJournal of Virology.  74:3871-3873. 2000
2000 Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopyJournal of Molecular Biology.  297:615-626. 2000
1999 Identification and characterization of the domain structure of bacteriophage P22 coat proteinBiochemistry.  38:14614-14623. 1999
1999 Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturationJournal of Molecular Biology.  287:527-538. 1999
1999 Mechanism of scaffolding-directed virus assembly suggested by comparison of scaffolding-containing and scaffolding-lacking P22 procapsidsBiophysical Journal.  76:3267-3277. 1999
1999 Solution x-ray scattering-based estimation of electron cryomicroscopy imaging parameters for reconstruction of virus particlesBiophysical Journal.  76:2249-2261. 1999
1998 Electrostatic interactions drive scaffolding/coat protein binding and procapsid maturation in bacteriophage P22Virology.  250:337-349. 1998
1998 Mechanism of capsid maturation in a double-stranded DNA virusProceedings of the National Academy of Sciences of USA.  95:9885-9890. 1998
1998 A helical coat protein recognition domain of the bacteriophage P22 scaffolding proteinJournal of Molecular Biology.  281:81-94. 1998
1998 Functional domains of bacteriophage P22 scaffolding proteinJournal of Molecular Biology.  281:69-79. 1998
1998 Inhibiting virus-capsid assembly by altering the polymerisation pathwayTrends in Biotechnology.  16:61-65. 1998
1998 Local rules simulation of the kinetics of virus capsid self-assemblyBiophysical Journal.  75:2626-2636. 1998
1997 Bacteriophage p22 scaffolding protein forms oligomers in solutionJournal of Molecular Biology.  268:655-665. 1997
1997 Cloning, purification, and preliminary characterization by circular dichroism and NMR of a carboxyl-terminal domain of the bacteriophage p22 scaffolding proteinProtein Science.  6:1583-1586. 1997
1996 Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopyJournal of Molecular Biology.  260:85-98. 1996
1996 Structural transitions in the scaffolding and coat proteins of P22 virus during assembly and disassemblyBiochemistry.  35:4619-4627. 1996
1996 The use of hydrostatic pressure as a tool to study viruses and other macromolecular assemblagesCurrent Opinion in Structural Biology.  6:166-175. 1996
1995 New high sensitivity sedimentation methods: Application to the analysis of the assembly of bacteriophage P22Techniques in Protein Chemistry.  6:427-432. 1995
1995 Role of Entropic Interactions in Viral Capsids: Single Amino Acid Substitutions in P22 Bacteriophage Coat Protein Resulting in Loss of Capsid StabilityBiochemistry.  34:1120-1126. 1995
1994 Pressure denaturation of the bacteriophage P22 coat protein and its entropic stabilization in icosahedral shellsBiophysical Journal.  66:1631-1641. 1994
1993 Assembly of bacteriophage P22: a model for ds-DNA virus assembly.Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale.  40:206-221. 1993
1993 Inhibition of Viral Capsid Assembly by 1,1′-Bi(4-anilinonaphthalene-5-sulfonic Acid)Biochemistry.  32:10658-10665. 1993
1993 Nucleation and growth phases in the polymerization of coat and scaffolding subunits into icosahedral procapsid shellsBiophysical Journal.  64:824-835. 1993
1993 Subunit Conformational Changes Accompanying Bacteriophage P22 Capsid MaturationBiochemistry.  32:537-543. 1993
1993 Three-dimensional transformation of capsids associated with genome packaging in a bacterial virusJournal of Molecular Biology.  231:65-74. 1993
1991 A pilot protein participates in the initiation of P22 procapsid assemblyVirology.  182:673-681. 1991
1990 Conformational States of the Bacteriophage P22 Capsid Subunit in Relation to Self-AssemblyBiochemistry.  29:5626-5633. 1990
1988 Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitroJournal of Molecular Biology.  202:743-757. 1988
1987 Structural Studies of Acetylated and Control Inner Core HistonesBiochemistry.  26:2944-2955. 1987
1983 Studies on synthetic chromatins containing poly(dA-dT)·poly(dA-dT) and poly(dG-dC)·poly(dG-dC)Biochimica et Biophysica Acta: Gene Regulatory Mechanisms.  739:85-96. 1983


Year Title Altmetric
2010 Investigating viral structure, function and dynamics with mass spectrometry.  103-130. 2010

Education And Training

  • Doctor of Philosophy in Biochemistry, Brandeis University 1985
  • Full Name

  • Peter Prevelige