• Dr. Paul MacLennan is an epidemiologist at the University of Alabama at Birmingham, where he is an Associate Professor of Surgery and Associate Director of Transplant Analytics, Informatics & Quality. His experience includes collaborations with researchers with diverse interests, including occupational exposures and mortality/cancer, health disparities, diabetes and vision, healthcare utilization, geriatric epidemiology, injury and trauma and solid organ transplantation. He currently serves as a study design and biostatistics expert in the UAB Center for Clinical and Translational Science, providing methodological consultations campus-wide to faculty, residents and students through the CCTS Biostatistics, Epidemiology and Research Design group. Over the course of his career, he has developed methodological expertise with all epidemiological study designs utilizing both primary and secondary data types from local and national sources for cross-sectional, retrospective, prospective, longitudinal and repeated measures data. In addition, MacLennan has expertise in data management and data linkages, methods for addressing missing data and advanced analyses using mathematical modeling for deriving measures of associations. Most recently, he has established an active collaboration with Dr. Jayme Locke, a UAB transplant surgeon-scientist, and coauthored more than 14 manuscripts with her over the past two years, consequently, enabling him to develop expertise in transplant outcomes. The pair's most recent collaboration has resulted in the development of a novel risk tool for potential kidney donors that incorporates APOL1 renal risk variants.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2022 Efficacy of hope: Analysis of organ quality and availability among deceased HIV-positive donorsTransplant Infectious Disease.  24. 2022
    2022 Associations between female birth sex and risk of chronic kidney disease development among people with HIV in the USA: A longitudinal, multicentre, cohort studyEClinicalMedicine.  53. 2022
    2022 Inter-Rater Reliability and Correlation of L1 Hounsfield Unit Measurements with DXA ScoresJournal of Clinical Densitometry.  25:668-673. 2022
    2022 Perpetuating Disparity: Failure of the Kidney Transplant System to Provide the Most Kidney Transplants to Communities With the Greatest NeedAnnals of Surgery.  276:597-604. 2022
    2022 Greater community vulnerability is associated with poor living donor navigator program fidelitySurgery.  172:997-1004. 2022
    2022 Change in Body Mass Index and Attributable Risk of New Onset Hypertension among Obese Living Kidney Donors.Annals of Surgery2022
    2022 Abnormal time-zero histology is predictive of kidney transplant outcomesClinical Transplantation.  36. 2022
    2022 Dialysis Nonadherence and Kidney Transplant Outcomes: A Retrospective Cohort StudyAmerican Journal of Kidney Diseases.  80:46-54. 2022
    2022 Association between Pentosan Polysulfate Sodium and Retinal DisordersJAMA Ophthalmology.  140:37-42. 2022
    2022 Reclassification of CKD in living kidney donors with the refitted race-free eGFR formula 2022
    2021 Evaluation of Community-Level Vulnerability and Racial Disparities in Living Donor Kidney TransplantJAMA Surgery.  156:1120-1129. 2021
    2021 Incorporation of a genetics-based information module into standardized diabetes patient educationPrimary Care Diabetes.  15:706-712. 2021
    2021 Self-advocacy is associated with lower likelihood of living donor kidney transplantation 2021
    2021 Effects of Geographic Redistribution Policy on Access to Organ Transplant-In ReplyJAMA Surgery.  156:289-290. 2021
    2021 To treat or not to treat: perceptions of the initial American Society for Reproductive Medicine COVID-19 recommendations among women’s health providersJournal of Assisted Reproduction and Genetics.  38:621-626. 2021
    2021 Achieving vancomycin troughs within goal range in low birth weight neonatesThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG.  26:56-61. 2021
    2021 Competing risks and the risks of children and adults competing for liversAmerican Journal of Transplantation.  21:13-14. 2021
    2020 Repeat Attending Exposure Influences Operative Autonomy in Endocrine Surgical ProceduresJournal of Surgical Education.  77:e71-e77. 2020
    2020 Exacerbating Racial Disparities in Kidney Transplant: The Consequences of Geographic RedistributionJAMA Surgery.  155:679-681. 2020
    2020 Patient-reported cognitive complaints in older adults with gastrointestinal malignancies at diagnosis– Results from the Cancer & Aging Resilience Evaluation (CARE) studyJournal of Geriatric Oncology.  11:982-988. 2020
    2020 Combined Thoracic-Kidney Transplantation Practices May Exacerbate Existing Geographic Disparities in Access to Deceased Donor Kidney TransplantationJournal of Heart and Lung Transplantation.  39:S366-S367. 2020
    2020 A Qualitative Assessment of the Living Donor Navigator Program to Identify Core Competencies and Promising Practices for Implementation 2020
    2020 Enhanced Advocacy and Health Systems Training through Patient Navigation Increases Access to Living-donor Kidney TransplantationTransplantation.  122-129. 2020
    2020 Geographic differences in population health and expected organ supply in the Gulf Coast Region of the United States compared to non-Gulf StatesTransplantation.  421-427. 2020
    2020 Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-year Single-center ExperienceAnnals of Surgery.  271:177-183. 2020
    2020 Using AIDET® Education Simulations to Improve Patient Experience ScoresClinical Simulation in Nursing.  38:14-17. 2020
    2019 Does Medicaid expansion improve access to care for the first-time shoulder dislocator?Journal of Shoulder and Elbow Surgery.  28:2079-2083. 2019
    2019 Donation approval among obese living kidney donor candidates: The impact of metabolic syndromeSurgery.  166:940-946. 2019
    2019 Mitigating Racial and Sex Disparities in Access to Living Donor Kidney Transplantation: Impact of the Nation's Longest Single-center Kidney ChainAnnals of Surgery.  270:639-646. 2019
    2019 Obesity and long-term mortality risk among living kidney donorsSurgery.  166:205-208. 2019
    2019 Center variation and risk factors for failure to complete 6 month postdonation follow-up among obese living kidney donorsTransplantation.  103:1450-1456. 2019
    2019 Ethnic and age disparities in outcomes among liver transplant waitlist candidatesTransplantation.  103:1425-1432. 2019
    2019 Optimal timing of hepatitis C treatment among HIV/HCV coinfected ESRD patients: Pre- vs posttransplantAmerican Journal of Transplantation.  19:1806-1819. 2019
    2019 Distracted Driving and Risk of Crash or Near-Crash Involvement among Older Drivers Using Naturalistic Driving Data with a Case-Crossover Study Design 2019
    2019 Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virusClinical Transplantation.  33. 2019
    2019 Fat embolism syndrome due to bone marrow necrosis in patients with hemoglobinopathies: A life-threatening complication mimicking thrombotic thrombocytopenic purpuraAmerican Journal of Hematology.  94:E64-E66. 2019
    2018 Population Health, Ethnicity, and Rate of Living Donor Kidney TransplantationTransplantation.  102:2080-2087. 2018
    2018 Population level outcomes and cost-effectiveness of hepatitis C treatment pre- vs postkidney transplantationAmerican Journal of Transplantation.  18:2483-2495. 2018
    2018 Impact of the new kidney allocation system A2/A2B → B policy on access to transplantation among minority candidatesAmerican Journal of Transplantation.  18:1947-1953. 2018
    2018 Decreasing deceased donor transplant rates among children (≤6 years) under the new kidney allocation systemAmerican Journal of Transplantation.  18:1690-1698. 2018
    2018 Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney DonorsAnnals of Surgery.  267:1161-1168. 2018
    2018 Kidney transplantation and waitlist mortality rates among candidates registered as willing to accept a hepatitis C infected kidneyTransplant Infectious Disease.  20. 2018
    2018 Landscape of ABO-Incompatible Live Donor Kidney Transplantation in the USJournal of the American College of Surgeons.  226:615-621. 2018
    2018 General cognitive impairment as a risk factor for motor vehicle collision involvement: A prospective population-based studyGeriatrics.  3. 2018
    2018 Living Kidney Donor Phenotype and Likelihood of Postdonation Follow-upTransplantation.  102:135-139. 2018
    2017 Impact of Protease Inhibitor–Based Anti-Retroviral Therapy on Outcomes for HIV+ Kidney Transplant RecipientsAmerican Journal of Transplantation.  17:3114-3122. 2017
    2017 Visual sensory and visual-cognitive function and rate of crash and near-crash involvement among older drivers using naturalistic driving data 2017
    2017 Obesity increases the risk of end-stage renal disease among living kidney donorsKidney International.  91:699-703. 2017
    2017 Survival benefit of kidney transplantation in HIV-infected patientsAnnals of Surgery.  265:604-608. 2017
    2017 Lymphocyte-depleting induction therapy lowers the risk of acute rejection in African American pediatric kidney transplant recipientsPediatric Transplantation.  21. 2017
    2017 Access to kidney transplantation among HIV-infected waitlist candidatesClinical Journal of the American Society of Nephrology.  12:467-475. 2017
    2017 Increased Mortality and Graft Loss With Kidney Retransplantation Among Human Immunodeficiency Virus (HIV)–Infected RecipientsAmerican Journal of Transplantation.  17:173-179. 2017
    2016 Dosing Eculizumab for Antibody-Mediated Rejection in Kidney Transplantation: A Case ReportTransplantation Proceedings.  48:3099-3105. 2016
    2016 Insurance Type and Solid Organ Transplantation Outcomes: A Historical Perspective on How Medicaid Expansion Might Impact Transplantation OutcomesJournal of the American College of Surgeons.  223:611-620.e4. 2016
    2016 Identification of Optimal Donor–Recipient Combinations Among Human Immunodeficiency Virus (HIV)–Positive Kidney Transplant RecipientsAmerican Journal of Transplantation.  16:2377-2383. 2016
    2016 Inpatient mortality among solid organ transplant recipients hospitalized for sepsis and severe sepsisClinical Infectious Diseases.  63:186-194. 2016
    2016 Comparison of posthospitalization function and community mobility in hospital mobility program and usual care patients a randomized clinical trialJAMA Internal Medicine.  176:921-927. 2016
    2016 Long-Term outcomes after liver transplantation among human immunodeficiency virus-infected recipientsTransplantation.  100:141-146. 2016
    2016 Screw versus pin fixation with open reduction of pediatric lateral condyle fractures 2016
    2015 Feasibility and efficacy of diabetic retinopathy screening among youth with diabetes in a pediatric endocrinology clinic: A cross-sectional studyDiabetology and Metabolic Syndrome.  7. 2015
    2015 A national study of outcomes among HIV-infected kidney transplant recipientsJournal of the American Society of Nephrology.  26:2222-2229. 2015
    2015 Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected RecipientsAmerican Journal of Transplantation.  15:2096-2104. 2015
    2015 The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costsAmerican Journal of Transplantation.  15:541-546. 2015
    2015 Altered lower extremity fracture characteristics in obese pediatric trauma patientsJournal of Orthopaedic Trauma.  29:e12-e17. 2015
    2014 A survey of Alabama eye care providers in 2010-2011BMC Ophthalmology.  14. 2014
    2014 The effect of trauma care on the temporal distribution of homicide mortality in Jefferson County, Alabama 2014
    2014 Eye care use among a high-risk diabetic population seen in a public hospital's clinicsJAMA Ophthalmology.  132:162-167. 2014
    2014 The effect of previous traumatic injury on homicide riskJournal of Forensic Sciences.  59:986-990. 2014
    2013 The deleterious effect of red blood cell storage on microvascular response to transfusionJournal of Trauma and Acute Care Surgery.  75:807-812. 2013
    2013 Effects of an acute care for elders unit on costs and 30-day readmissionsJAMA Internal Medicine.  173:981-987. 2013
    2013 Driving with pets as a risk factor for motor vehicle collisions among older driversAccident Analysis and Prevention.  58:70-74. 2013
    2013 Medical record validation of self-reported eye diseases and eye care utilization among older adultsCurrent Eye Research.  38:1-8. 2013
    2012 Pediatric obesity and traumatic lower-extremity long-bone fracture outcomesJournal of Trauma and Acute Care Surgery.  73:966-971. 2012
    2012 Changes in eye protection behavior following an occupational eye injuryWorkplace Health and Safety.  60:393-400. 2012
    2012 Stress-induced hyperglycemia, not diabetic hyperglycemia, is associated with higher mortality in traumaAnnals of Surgery.  256:446-452. 2012
    2012 The epidemiology of chemical eye injuriesCurrent Eye Research.  37:787-793. 2012
    2012 Accounting for differences in transfusion volume: Are all massive transfusions created equal?Journal of Trauma and Acute Care Surgery.  72:1536-1540. 2012
    2012 Microvascular response to red blood cell transfusion in trauma patientsShock.  37:276-281. 2012
    2012 A case-crossover study of risk factors for occupational eye injuriesJournal of Occupational and Environmental Medicine.  54:42-47. 2012
    2011 A review of epidemiologic studies of triazine herbicides and cancerCritical Reviews in Toxicology.  41:1-34. 2011
    2010 Changing Paradigms of Seat Belt and Air Bag InjuriesJournal of the American College of Surgeons.  211:147-148. 2010
    2009 Surgeons' attitudes and practices in the utilization of palliative and supportive care services for patients with a sudden advanced illnessJournal of Palliative Medicine.  12:1037-1042. 2009
    2009 Body mass index affects time to definitive closure after damage control surgeryJournal of Trauma and Acute Care Surgery.  66:1683-1687. 2009
    2009 Reassessment of the tri-modal mortality distribution in the presence of a regional trauma systemJournal of Trauma and Acute Care Surgery.  66:526-530. 2009
    2008 Injury risks between first- and second-generation airbags in frontal motor vehicle collisionsAccident Analysis and Prevention.  40:1371-1374. 2008
    2008 Vehicle rollover risk and electronic stability control systemsInjury Prevention.  14:154-158. 2008
    2008 The incidence of shopping cart-related injuries in the United States, 2002-2006Accident Analysis and Prevention.  40:1253-1256. 2008
    2007 Agreement between prehospital and emergency department Glasgow coma scoresJournal of Trauma and Acute Care Surgery.  63:1026-1031. 2007
    2007 Body mass index affects the need for and the duration of mechanical ventilation after thoracic traumaJournal of Trauma and Acute Care Surgery.  62:1432-1435. 2007
    2007 Body mass index affects the need for and the duration of mechanical ventilation after thoracic trauma. 2007
    2006 Motor vehicle restraint system use and risk of spine injuryTraffic Injury Prevention.  7:256-263. 2006
    2006 The contribution of opiate analgesics to the development of infectious complications in burn patients 2006
    2006 Trauma center resource consumption and mortality 2006
    2005 The impact of combined trauma and burns on patient mortalityJournal of Trauma and Acute Care Surgery.  58:284-288. 2005
    2005 Motor vehicle mismatch-related spinal injuryJournal of Spinal Cord Medicine.  28:314-319. 2005
    2005 The Association Between Restraint System and Upper Extremity Injury After Motor Vehicle CollisionsJournal of Orthopaedic Trauma.  19:529-534. 2005
    2005 Unusual job activities as a risk factor for occupational injuriesOccupational Medicine.  55:66-68. 2005
    2004 Risk of injury for occupants of motor vehicle collisions from unbelted occupantsInjury Prevention.  10:363-367. 2004
    2004 The association between body mass index and diaphragm injury among motor vehicle collision occupantsJournal of Trauma and Acute Care Surgery.  57:1324-1328. 2004
    2004 A cross-sectional study of triallate exposure and neurological health among workers at a pesticide manufacturing and formulating facilityOccupational and Environmental Medicine.  61:936-944. 2004
    2004 Is seat belt use associated with fewer days of lost work after motor vehicle collisions?Journal of Trauma and Acute Care Surgery.  56:1009-1014. 2004
    2004 Cervical Spine Injury and Restraint System Use in Motor Vehicle CollisionsSpine.  29:386-389. 2004
    2004 Effect of Restraint Systems on Maxillofacial Injury in Frontal Motor Vehicle CollisionsJournal of oral surgery, anesthesia, and hospital dental service.  62:571-575. 2004
    2004 Is seat belt use associated with fewer days of lost work after motor vehicle collisions? 2004
    2004 Preexisting conditions and mortality in older trauma patientsJournal of Trauma and Acute Care Surgery.  56:1291-1296. 2004
    2003 Early versus delayed fixation of pelvic ring fractures 2003
    2003 Cancer incidence among triazine herbicide manufacturing workers [1] (multiple letters)Journal of Occupational and Environmental Medicine.  45:343-344. 2003
    2003 Mortality among triazine herbicide manufacturing workers 2003
    2003 Motor vehicle crash-related mortality is associated with prehospital and hospital-based resource availabilityJournal of Trauma and Acute Care Surgery.  54:273-279. 2003
    2002 Cancer incidence among triazine herbicide manufacturing workersJournal of Occupational and Environmental Medicine.  44:1048-1058. 2002

    Research Overview

  • abdominal transplantation, incompatible organ transplantation, transplantation of HIV-infected end-stage patients, outcomes and behavioral research focused on health disparities
  • Investigator On

  • Alpha-Galactosidase A and Glycosphingolipid Metabolites as Putative Biomarkers for PD  awarded by Fox (Michael J.) Foundation for Parkinson's Research
  • CKD Risk Prediction among Obese Living Kidney Donors  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Center for Clinical and Translational Science (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS
  • Crash Injury Research and Engineering Network (CIREN)  awarded by National Highway Traffic Safety Administration
  • Establishing Normative Cognitive Data for UAB Medical Professionals  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • HOPE in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation  awarded by Johns Hopkins University
  • Hope in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation  awarded by Johns Hopkins University
  • Improving Access to and Quality Eye Care in an At-Risk, Underserved Population  awarded by National Center for Chronic Disease Prevention & Health Promo./CDC/DHHS
  • Long-Term Outcomes Among Living Kidney Donors with Isolated Medical Abnormalities  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Prospective Observational Study of HIV+ Deceased Donor Transplant for HIV+ Recipients  awarded by Johns Hopkins University
  • RBC Age and Potentiation of Transfusion Related Pathology in Trauma Patients  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Education And Training

  • Doctor of Philosophy in Epidemiology, University of Alabama at Birmingham 2002
  • Master of Public Health, University of Alabama at Birmingham 1995
  • Full Name

  • Paul MacLennan