• Dr. Paul MacLennan is an epidemiologist at the University of Alabama at Birmingham, where he is an Associate Professor of Surgery and Associate Director of Transplant Analytics, Informatics & Quality. His experience includes collaborations with researchers with diverse interests, including occupational exposures and mortality/cancer, health disparities, diabetes and vision, healthcare utilization, geriatric epidemiology, injury and trauma and solid organ transplantation. He currently serves as a study design and biostatistics expert in the UAB Center for Clinical and Translational Science, providing methodological consultations campus-wide to faculty, residents and students through the CCTS Biostatistics, Epidemiology and Research Design group. Over the course of his career, he has developed methodological expertise with all epidemiological study designs utilizing both primary and secondary data types from local and national sources for cross-sectional, retrospective, prospective, longitudinal and repeated measures data. In addition, MacLennan has expertise in data management and data linkages, methods for addressing missing data and advanced analyses using mathematical modeling for deriving measures of associations. Most recently, he has established an active collaboration with Dr. Jayme Locke, a UAB transplant surgeon-scientist, and coauthored more than 14 manuscripts with her over the past two years, consequently, enabling him to develop expertise in transplant outcomes. The pair's most recent collaboration has resulted in the development of a novel risk tool for potential kidney donors that incorporates APOL1 renal risk variants.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2020 Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-year Single-center Experience 2020
    2018 Population Health, Ethnicity, and Rate of Living Donor Kidney Transplantation 2018
    2018 Population level outcomes and cost-effectiveness of hepatitis C treatment pre- vs postkidney transplantation 2018
    2018 Impact of the new kidney allocation system A2/A2B → B policy on access to transplantation among minority candidates 2018
    2018 Decreasing deceased donor transplant rates among children (≤6 years) under the new kidney allocation system 2018
    2018 Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney Donors 2018
    2018 Kidney transplantation and waitlist mortality rates among candidates registered as willing to accept a hepatitis C infected kidney 2018
    2018 Landscape of ABO-Incompatible Live Donor Kidney Transplantation in the US 2018
    2018 Living Kidney Donor Phenotype and Likelihood of Postdonation Follow-up 2018
    2017 Impact of Protease Inhibitor–Based Anti-Retroviral Therapy on Outcomes for HIV+ Kidney Transplant Recipients 2017
    2017 Visual sensory and visual-cognitive function and rate of crash and near-crash involvement among older drivers using naturalistic driving data 2017
    2017 Obesity increases the risk of end-stage renal disease among living kidney donors 2017
    2017 Survival benefit of kidney transplantation in HIV-infected patients 2017
    2017 Lymphocyte-depleting induction therapy lowers the risk of acute rejection in African American pediatric kidney transplant recipients 2017
    2017 Access to kidney transplantation among HIV-infected waitlist candidates 2017
    2017 Increased Mortality and Graft Loss With Kidney Retransplantation Among Human Immunodeficiency Virus (HIV)–Infected Recipients 2017
    2016 Dosing Eculizumab for Antibody-Mediated Rejection in Kidney Transplantation: A Case Report 2016
    2016 Insurance Type and Solid Organ Transplantation Outcomes: A Historical Perspective on How Medicaid Expansion Might Impact Transplantation Outcomes 2016
    2016 Identification of Optimal Donor–Recipient Combinations Among Human Immunodeficiency Virus (HIV)–Positive Kidney Transplant Recipients 2016
    2016 Comparison of posthospitalization function and community mobility in hospital mobility program and usual care patients a randomized clinical trial 2016
    2016 Inpatient mortality among solid organ transplant recipients hospitalized for sepsis and severe sepsis 2016
    2016 Long-Term outcomes after liver transplantation among human immunodeficiency virus-infected recipients 2016
    2016 Screw versus pin fixation with open reduction of pediatric lateral condyle fractures 2016
    2015 Feasibility and efficacy of diabetic retinopathy screening among youth with diabetes in a pediatric endocrinology clinic: A cross-sectional study 2015
    2015 Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients 2015
    2015 Altered lower extremity fracture characteristics in obese pediatric trauma patients 2015
    2015 A national study of outcomes among HIV-infected kidney transplant recipients 2015
    2015 The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs 2015
    2014 A survey of Alabama eye care providers in 2010-2011 2014
    2014 Eye care use among a high-risk diabetic population seen in a public hospital's clinics 2014
    2014 The effect of previous traumatic injury on homicide risk 2014
    2014 The effect of trauma care on the temporal distribution of homicide mortality in Jefferson County, Alabama 2014
    2013 The deleterious effect of red blood cell storage on microvascular response to transfusion 2013
    2013 Effects of an acute care for elders unit on costs and 30-day readmissions 2013
    2013 Driving with pets as a risk factor for motor vehicle collisions among older drivers 2013
    2013 Medical record validation of self-reported eye diseases and eye care utilization among older adults 2013
    2012 Pediatric obesity and traumatic lower-extremity long-bone fracture outcomes 2012
    2012 Changes in eye protection behavior following an occupational eye injury 2012
    2012 Stress-induced hyperglycemia, not diabetic hyperglycemia, is associated with higher mortality in trauma 2012
    2012 The epidemiology of chemical eye injuries 2012
    2012 Accounting for differences in transfusion volume: Are all massive transfusions created equal? 2012
    2012 Microvascular response to red blood cell transfusion in trauma patients 2012
    2012 A case-crossover study of risk factors for occupational eye injuries 2012
    2011 A review of epidemiologic studies of triazine herbicides and cancer 2011
    2010 Changing Paradigms of Seat Belt and Air Bag Injuries 2010
    2009 Surgeons' attitudes and practices in the utilization of palliative and supportive care services for patients with a sudden advanced illness 2009
    2009 Body mass index affects time to definitive closure after damage control surgery 2009
    2009 Reassessment of the tri-modal mortality distribution in the presence of a regional trauma system 2009
    2008 Injury risks between first- and second-generation airbags in frontal motor vehicle collisions 2008
    2008 Vehicle rollover risk and electronic stability control systems 2008
    2008 The incidence of shopping cart-related injuries in the United States, 2002-2006 2008
    2007 Agreement between prehospital and emergency department Glasgow coma scores 2007
    2007 Body mass index affects the need for and the duration of mechanical ventilation after thoracic trauma 2007
    2007 Body mass index affects the need for and the duration of mechanical ventilation after thoracic trauma. 2007
    2006 Motor vehicle restraint system use and risk of spine injury 2006
    2006 The contribution of opiate analgesics to the development of infectious complications in burn patients 2006
    2006 Trauma center resource consumption and mortality 2006
    2005 The impact of combined trauma and burns on patient mortality 2005
    2005 Motor vehicle mismatch-related spinal injury 2005
    2005 The Association Between Restraint System and Upper Extremity Injury After Motor Vehicle Collisions 2005
    2005 Unusual job activities as a risk factor for occupational injuries 2005
    2004 Risk of injury for occupants of motor vehicle collisions from unbelted occupants 2004
    2004 The association between body mass index and diaphragm injury among motor vehicle collision occupants 2004
    2004 A cross-sectional study of triallate exposure and neurological health among workers at a pesticide manufacturing and formulating facility 2004
    2004 Is seat belt use associated with fewer days of lost work after motor vehicle collisions? 2004
    2004 Cervical Spine Injury and Restraint System Use in Motor Vehicle Collisions 2004
    2004 Effect of Restraint Systems on Maxillofacial Injury in Frontal Motor Vehicle Collisions 2004
    2004 Is seat belt use associated with fewer days of lost work after motor vehicle collisions? 2004
    2004 Preexisting conditions and mortality in older trauma patients 2004
    2003 Early versus delayed fixation of pelvic ring fractures 2003
    2003 Cancer incidence among triazine herbicide manufacturing workers [1] (multiple letters) 2003
    2003 Mortality among triazine herbicide manufacturing workers 2003
    2003 Motor vehicle crash-related mortality is associated with prehospital and hospital-based resource availability 2003
    2002 Cancer incidence among triazine herbicide manufacturing workers 2002

    Research Overview

  • abdominal transplantation, incompatible organ transplantation, transplantation of HIV-infected end-stage patients, outcomes and behavioral research focused on health disparities
  • Investigator On

  • Center for Clinical and Translational Science (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS 2019 - 2024
  • CKD Risk Prediction among Obese Living Kidney Donors  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2017 - 2022
  • HOPE in Action: A Clinical Trial of HIV-to-HIV Liver Transplantation  awarded by Johns Hopkins University 2019 - 2020
  • Long-Term Outcomes Among Living Kidney Donors with Isolated Medical Abnormalities  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2019
  • Prospective Observational Study of HIV+ Deceased Donor Transplant for HIV+ Recipients  awarded by Johns Hopkins University 2018 - 2019
  • Improving Access to and Quality Eye Care in an At-Risk, Underserved Population  awarded by National Center for Chronic Disease Prevention & Health Promo./CDC/DHHS 2010 - 2016
  • Alpha-Galactosidase A and Glycosphingolipid Metabolites as Putative Biomarkers for PD  awarded by Fox (Michael J.) Foundation for Parkinson's Research 2013 - 2015
  • Crash Injury Research and Engineering Network (CIREN)  awarded by National Highway Traffic Safety Administration 2010 - 2015
  • RBC Age and Potentiation of Transfusion Related Pathology in Trauma Patients  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2014
  • Education And Training

  • Doctor of Philosophy in Epidemiology, University of Alabama at Birmingham 2002
  • Master of Public Health, University of Alabama at Birmingham 1995
  • Full Name

  • Paul MacLennan