Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Synthesis and Evaluation of QS-7-Based Vaccine AdjuvantsACS Infectious Diseases.  5:974-981. 2019
2019 Synthesis and Evaluation of a QS-17/18-Based Vaccine AdjuvantJournal of Medicinal Chemistry.  62:1669-1676. 2019
2019 Specific RANK Cytoplasmic Motifs Drive OsteoclastogenesisJournal of Bone and Mineral Research2019
2018 Phosphatidylinositol 3-Kinase/Akt signal pathway resists the apoptosis and inflammation in human extravillous trophoblasts induced by Porphyromonas gingivalisMolecular Immunology.  104:100-107. 2018
2018 Periodontal infection with Porphyromonas gingivalis induces preterm birth and lower birth weight in ratsOral Microbiology and Immunology.  33:312-321. 2018
2017 Phenotype and function of myeloidderived suppressor cells induced by Porphyromonas gingivalis infectionInfection and Immunity.  85. 2017
2016 Synthesis and Evaluation of QS-21-Based Immunoadjuvants with a Terminal-Functionalized Side Chain Incorporated in the West Wing TrisaccharideJournal of Organic Chemistry.  81:9560-9566. 2016
2016 Effects of 1,25-dihydroxyvitamin D3 on macrophage cytokine secretion stimulated by Porphyromonas gingivalisJapanese Journal of Infectious Diseases.  69:482-487. 2016
2015 IL-1R/TLR2 through MyD88 divergently modulates osteoclastogenesis through regulation of nuclear factor of activated T cells c1 (NFATc1) and B lymphocyte-induced maturation protein-1 (Blimp1)Journal of Biological Chemistry.  290:30163-30174. 2015
2015 Extensive description and comparison of human supra-gingival microbiome in root caries and healthPLoS ONE.  10. 2015
2015 Comparison of immunological and microbiological characteristics in children and the elderly with or without dental cariesEuropean Journal of Oral Sciences.  123:80-87. 2015
2013 Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophagesPLoS ONE.  8. 2013
2013 Synthesis of QS-21-based immunoadjuvantsJournal of Organic Chemistry.  78:11525-11534. 2013
2012 Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesisJournal of Biological Chemistry.  287:15728-15738. 2012
2011 Contribution of a Streptococcus mutans antigen expressed by a Salmonella vector vaccine in dendritic cell activationInfection and Immunity.  79:3792-3800. 2011
2011 TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-κBJournal of Biological Chemistry.  286:24159-24169. 2011
2011 VDR deficiency affects alveolar bone and cementum apposition in miceArchives of Oral Biology.  56:672-677. 2011
2009 Normalisation of calcium status reverses the phenotype in dentin, but not in enamel of VDR-deficient miceArchives of Oral Biology.  54:1105-1110. 2009
2009 Molecular mechanism of the bifunctional role of lipopolysaccharide in osteoclastogenesisJournal of Biological Chemistry.  284:12512-12523. 2009
2009 Different enamel and dentin mineralization observed in VDR deficient mouse modelArchives of Oral Biology.  54:299-305. 2009
2009 Glycogen synthase kinase-3β (GSK3β) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in miceMolecular Immunology.  46:677-687. 2009
2008 TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensisJournal of Leukocyte Biology.  84:1434-1446. 2008
2008 Sec translocase and sortase A are colocalised in a locus in the cytoplasmic membrane of Streptococcus mutansArchives of Oral Biology.  53:150-154. 2008
2008 Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responsesJournal of Experimental Medicine.  205:79-90. 2008
2007 Role of CD80 and CD86 in host immune responses to the recombinant hemagglutinin domain of Porphyromonas gingivalis gingipain and in the adjuvanticity of cholera toxin B and monophosphoryl lipid AVaccine.  25:6201-6210. 2007
2006 Immunogenicity of Salmonella vector vaccines expressing SBR of Streptococcus mutans under the control of a T7-nirB (dual) promoter systemVaccine.  24:5003-5015. 2006
2006 Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVSInfection and Immunity.  74:2809-2816. 2006
2005 Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalisVaccine.  23:4734-4744. 2005
2005 Role of mitogen-activated protein kinases and NF-κB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin BInfection and Immunity.  73:3990-3998. 2005
2004 [Preliminary study on gene related to acid tolerance of Streptococcus mutans].Zhonghua Kouqiangke Zazhi.  39:382-385. 2004
2004 Role of B7 Costimulatory Molecules in Immune Responses and T-Helper Cell Differentiation in Response to Recombinant HagB from Porphyromonas gingivalisInfection and Immunity.  72:637-644. 2004
2004 Effect of a separated instrument on bacterial penetration of obturated root canalsJournal of Endodontics.  30:177-179. 2004
2004 Effectiveness of sodium hypochlorite in preventing inoculation of periapical tissues with contaminated patency filesJournal of Endodontics.  30:92-94. 2004
2004 pH required to kill Enterococcus faecalis in vitroJournal of Endodontics.  30:218-219. 2004
2003 Effectiveness of the quillaja saponin semi-synthetic analog GPI-0100 in potentiating mucosal and systemic responses to recombinant HagB from Porphyromonas gingivalisVaccine.  21:4459-4471. 2003
2002 Enhanced immunogenicity of a genetic chimeric protein consisting of two virulence antigens of Streptococcus mutans and protection against infectionInfection and Immunity.  70:6779-6787. 2002
2002 Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipainsInfection and Immunity.  70:2512-2518. 2002
2001 Effect of attenuated Salmonella enterica serovar Typhimurium expressing a Streptococcus mutans antigen on secondary responses to the cloned proteinInfection and Immunity.  69:6604-6611. 2001
1999 Immunolabeling of the major cell surface protein antigen of Streptococcus sobrinus with monoclonal antibody.Chinese Journal of Dental Research.  2:23-26. 1999
1999 [Immunization against dental caries: current strategies].Zhonghua Kouqiangke Zazhi.  34:69-72. 1999
1999 Effects of monoclonal antibody on colonization of Streptococcus sobrinus and development of dental caries in rats.Chinese Journal of Dental Research.  2:12-15. 1999

Education And Training

  • Doctor of Philosophy in Oral Biology and Oral and Maxillofacial Pathology, Hubei University of Medicine 1997
  • Doctor of Dental Science in Dentistry, Hubei University of Medicine 1992
  • Full Name

  • Ping Zhang