Paula Chandler-Laney

Paula Chandler-Laney
Associate Professor

Associate Scientist (C), Comprehensive Diabetes Center , School of Medicine
Scholar (C), Center for Clinical and Translational Science (CCTS) , General Clinical Research Center
Associate Scientist (C), Center for Women's Reproductive Health , General Clinical Research Center
Associate Professor (P), Nutrition Sciences , School of Health Professions
PhD Program Director, Nutrition Sciences Education , Nutrition Sciences
Associate Scientist (C), Nutrition Obesity Res Center (NORC) , Nutrition Sciences Research

Overview

Dr. Chandler-Laney is an Associate Professor and Director of the PhD program in the Department of Nutrition Sciences. Her research focuses on elucidating the biobehavioral mechanisms that underlie the development of pediatric obesity, with a particular emphasis on understanding the role of the in utero environment in programming children's risk for obesity and cardiometabolic disease. This research involves studies of children, infants, and pregnant women. Methodologies include the assessment of body composition, biomarkers of cardiometabolic health, post-meal changes in glucose, insulin, and gut hormones, indirect calorimetry to assess resting metabolic rate and substrate metabolism, along with appetite regulation and eating behavior.
In addition to serving as program director for the PhD program, Dr. Chandler-Laney mentors several students and postdocs, and teaches an elective course to provide structure and guidance for Nutrition Sciences PhD students when writing manuscripts and grant proposals.

Selected Publications

Academic Article

Year	Title	Altmetric
2021	Secondary analysis of gut hormone data from children with and without in utero exposure to gestational diabetes: Differences in the associations among ghrelin, GLP-1, and insulin secretion. Pediatric Obesity. 16. 2021
2021	Changes in Ghrelin and Glucagon following a Low Glycemic Load Diet in Women with PCOS. Journal of Clinical Endocrinology and Metabolism. 106:e2151-e2161. 2021
2021	Percent Body Fat Content Measured by Plethysmography in Infants Randomized to High- or Usual-Volume Feeding after Very Preterm Birth. Journal of Pediatrics. 230:251-254.e3. 2021
2020	Serial assessment of fat and fat-free mass accretion in very preterm infants: a randomized trial. Pediatric Research. 88:733-738. 2020
2020	Association of gestational diabetes with child feeding practices: A secondary analysis using data from mother-child dyads in the deep south. Appetite. 151. 2020
2020	Quantitative assessment of nutritive sucking patterns in preterm infants. Early Human Development. 146. 2020
2020	Ratings of Perceived Exertion During Walking Predicts Endurance Independent of Physiological Effort in Older Women. Journal of Strength and Conditioning Research. 34:1340-1344. 2020
2020	Parental Self-Efficacy in New Mothers Predicts Infant Growth Trajectories. Western Journal of Nursing Research. 42:254-261. 2020
2020	Associations Among Maternal Adiposity, Insulin, and Adipokines in Circulation and Human Milk. Journal of Human Lactation. 2020
2020	Factors Associated with Appropriate Gestational Weight Gain among Women with Obesity 2020
2020	Modified eating in the absence of hunger test is associated with appetitive traits in infants. Eating Behaviors. 36. 2020
2020	The relationship between hourly energy balance and fat mass in female collegiate soccer players 2020
2019	Do Women Know Their Prepregnancy Weight? 2019
2019	Self-efficacy, infant feeding practices, and infant weight gain: An integrative review. Journal of Child Health Care. 23:286-310. 2019
2019	Reasons for Late-Night Eating and Willingness to Change:A Qualitative Study in Pregnant Black Women 2019
2019	In-home obesity prevention in low-income infants through maternal and social transmission. Contemporary Clinical Trials. 77:61-69. 2019
2018	Associations of neonatal adiponectin and leptin with growth and body composition in African American infants. Pediatric Obesity. 13:485-491. 2018
2018	Association of early pregnancy body mass index with post-partum weight change among African-American women. Clinical Obesity. 8:170-175. 2018
2018	Children's food and satiety responsiveness in association with post-prandial glucose following a standardized liquid meal. Clinical Obesity. 8:39-42. 2018
2018	Dietary Patterns Among Overweight and Obese African-American Women Living in the Rural South. Journal of Racial and Ethnic Health Disparities. 5:141-150. 2018
2017	Longitudinal Analysis of Nut-Inclusive Diets and Body Mass Index Among Overweight and Obese African American Women Living in Rural Alabama and Mississippi, 2011-2013 2017
2016	Association of late-night carbohydrate intake with glucose tolerance among pregnant African American women. Maternal and Child Nutrition. 12:688-698. 2016
2016	Ethnic differences in the consistency and accuracy of perceived exertion. American Journal of Human Biology. 28:398-404. 2016
2016	Relatively low β-cell responsiveness contributes to the association of BMI with circulating glucose concentrations measured under free-living conditions among pregnant African American women 2016
2015	Prospective associations of eating behaviors with weight gain in infants 2015
2015	Monitoring of infant feeding behavior using a jaw motion sensor. Journal of Healthcare Engineering. 6:23-40. 2015
2014	Return of hunger following a relatively high carbohydrate breakfast is associated with earlier recorded glucose peak and nadir. Appetite. 80:236-241. 2014
2014	Arterial elasticity, strength, fatigue, and endurance in older women. BioMed Research International. 2014. 2014
2014	Effects of a eucaloric reduced-carbohydrate diet on body composition and fat distribution in women with PCOS 2014
2014	Gut hormone activity of children born to women with and without gestational diabetes. Pediatric Obesity. 9:53-62. 2014
2014	Use of a simple liquid meal test to evaluate insulin sensitivity and beta-cell function in children. Pediatric Obesity. 9:102-110. 2014
2013	Favourable metabolic effects of a eucaloric lower-carbohydrate diet in women with PCOS. Clinical Endocrinology. 79:550-557. 2013
2013	Effects of diet macronutrient composition on body composition and fat distribution during weight maintenance and weight loss 2013
2013	Effects of diet macronutrient composition on body composition and fat distribution during weight maintenance and weight loss 2013
2013	Gestational and early life influences on infant body composition at 1 year 2013
2013	Gestational and early life influences on infant body composition at 1 year. 2013
2012	Common variants in the LAMA5 gene associate with fasting plasma glucose and serum triglyceride levels in a cohort of pre- and early pubertal children.. Journal of Pediatric Genetics. 1:229-234. 2012
2012	Body composition at 6 months of life: Comparison of air displacement plethysmography and dual-energy X-ray absorptiometry 2012
2012	Effects of habitual diet on ethnic differences in serum total ghrelin. Endocrine. 42:359-365. 2012
2012	Higher postprandial serum ghrelin among African-American girls before puberty. Journal of Pediatric Endocrinology and Metabolism. 25:691-696. 2012
2012	Circulating ghrelin and GLP-1 are not affected by habitual diet. Regulatory Peptides. 176:1-5. 2012
2012	A higher-carbohydrate, lower-fat diet reduces fasting glucose concentration and improves β-cell function in individuals with impaired fasting glucose 2012
2012	Overweight status and intrauterine exposure to gestational diabetes are associated with children's metabolic health. Pediatric Obesity. 7:44-52. 2012
2012	Common variants in the LAMA5 gene associate with fasting plasma glucose and serum triglyceride levels in a cohort of pre-and early pubertal children. Journal of Pediatric Genetics. 1:229-234. 2012
2011	Dietary macronutrient composition affects β cell responsiveness but not insulin sensitivity. American Journal of Clinical Nutrition. 94:120-127. 2011
2011	Higher maternal gestational glucose concentration is associated with lower offspring insulin sensitivity and altered β-cell function. Journal of Clinical Endocrinology and Metabolism. 96. 2011
2011	Maternal obesity, metabolic health, and prenatal programming of offspring obesity. Open Obesity Journal. 3:42-50. 2011
2011	Age-related changes in insulin sensitivity and β-cell function among European-American and African-American women 2011
2011	Maternal glucose concentration during pregnancy predicts fat and lean mass of prepubertal offspring. Diabetes Care. 34:741-745. 2011
2010	Possible link between mothers high blood sugar during pregnancy and childrens reduced insulin sensitivity?. Pediatric Health. 4:561-563. 2010
2010	Adiposity and Β-cell function: Relationships differ with ethnicity and age 2010
2010	Glucose metabolism and diet predict changes in adiposity and fat distribution in weight-reduced women 2010
2010	Perception of exercise difficulty predicts weight regain in formerly overweight women 2010
2010	Exercise training prevents regain of visceral fat for 1 year following weight loss 2010
2010	Fat distribution, aerobic fitness, blood lipids, and insulin sensitivity in African-American and European-American women 2010
2010	Ethnicity-specific anthropometric predictors of metabolic risk in women.. International Journal of Body Composition Research. 8:69-76. 2010
2010	Self-reported low vitality, poor mental health, and low dietary restraint are associated with overperception of physical exertion. Journal of Obesity. 2010. 2010
2009	Associations among body size dissatisfaction, perceived dietary control, and diet history in African American and European American women. Eating Behaviors. 10:202-208. 2009
2009	Perception of Others' Body Size Influences Weight Loss and Regain for European American but Not African American Women. Health Psychology. 28:414-418. 2009
2009	Effect of dietary adherence with or without exercise on weight loss: A mechanistic approach to a global problem. Journal of Clinical Endocrinology and Metabolism. 94:1602-1607. 2009
2008	Effect of a cage divider permitting social stimuli on stress and food intake in rats. Physiology and Behavior. 95:222-228. 2008
2007	High intake of palatable food predicts binge-eating independent of susceptibility to obesity: An animal model of lean vs obese binge-eating and obesity with and without binge-eating. International Journal of Obesity. 31:1357-1367. 2007
2007	Body composition and endocrine status of long-term stress-induced binge-eating rats. Physiology and Behavior. 91:424-431. 2007
2007	A history of caloric restriction induces neurochemical and behavioral changes in rats consistent with models of depression 2007
2007	A history of human-like dieting alters serotonergic control of feeding and neurochemical balance in a rat model of binge-eating. International Journal of Eating Disorders. 40:136-142. 2007
2006	Binge eating in rats produced by combining dieting with stress.. Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.]. Chapter 9. 2006
2005	PYY3-36 as an anti-obesity drug target. Obesity Reviews. 6:307-322. 2005
2005	Combined dieting and stress evoke exaggerated responses to opioids in binge-eating rats. Behavioral Neuroscience. 119:1207-1214. 2005
2005	Feeding response to melanocortin agonist predicts preference for and obesity from a high-fat diet. Physiology and Behavior. 85:221-230. 2005
2004	Stress and hunger alter the anorectic efficacy of fluoxetine in binge-eating rats with a history of caloric restriction. International Journal of Eating Disorders. 36:328-341. 2004
2004	Erratum: Does gut hormone PVY3-36 decrease food intake in rodents? (Nature (2004) 430 (165) DOI:10.1038/nature03019). Nature. 431:414. 2004
2004	Change in CCK-8 response after diet-induced obesity and MC3/4-receptor blockade. Peptides. 25:299-306. 2004
2004	Jejunal administration of linoleic acid increases activity of neurons in the paraventricular nucleus of the hypothalamus 2004
2004	Jejunal administration of linoleic acid increases activity of neurons in the paraventricular nucleus of the hypothalamus. 2004
2004	Physiology: does gut hormone PYY3-36 decrease food intake in rodents?. Nature. 430. 2004
2003	The role of palatable food and hunger as trigger factors in an animal model of stress induced binge eating. International Journal of Eating Disorders. 34:183-197. 2003
2003	The CNS melanocortin system: A biological weapon against the threat of obesity. Current Medicinal Chemistry Central Nervous System Agents. 3:201-215. 2003
2002	A new animal model of binge eating: Key synergistic role of past caloric restriction and stress. Physiology and Behavior. 77:45-54. 2002
2002	Incidence of chaotic eating behaviors in binge-eating disorder: Contributing factors 2002

Research Overview

Biobehavioral mechanisms that underlie obesity and cardiometabolic disease.
Role of physiology and behavior in appetite regulation.
Developmental origins of obesity.
Maternal weight and diabetes status during pregnancy and long-term health of women and children.