Positions

Overview

  • Our laboratory concentrates on understanding the immune correlates of protection against HIV disease progression with a focus on cell medicated immune responses (CD4 and CD8 T cells). We are utilizing a variety of techniques in our laboratory to evaluate the quality of HIV-specific T cell responses observed in patients who represent the entire spectra of HIV disease. These assays include an in vitro HIV killing and an in vitro HIV viral suppression assay. These assays measure the actual clearance of virus, which has not been the focus of many CD8 T cell assays in the past. Our plan is to use these assays to measure differences in viral clearance among those chronically infected patients with varying degrees of immune control. We would also like to compare these types of responses in acutely infected patients to see how they change over the course of infection. The ultimate goal of this work is to use our findings to aid the development of an effective HIV vaccine to prevent infection and disease progression by more fully understanding correlates of immune control by T cells. He is also the director for the Alabama Vaccine Research Clinic, which conducts clinical trials of candidate vaccines. His main focus is the phase 1 and 2 testing of vaccines designed to prevent HIV infection or disease progression. These studies are preformed in conjunction with the HIV Vaccine Trials Unit.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 Cross-Reactivity to Mutated Viral Immune Targets Can Influence CD8+ T Cell Functionality: An Alternative Viral Adaptation StrategyFrontiers in Immunology.  12. 2021
    2021 Predictors of Nonseroconversion after SARS-CoV-2 InfectionEmerging Infectious Diseases.  27:2454-2458. 2021
    2021 HLA-E–restricted HIV-1–specific CD8+ T cell responses in natural infectionJournal of Clinical Investigation.  131. 2021
    2021 Duration of post-COVID-19 symptoms is associated with sustained SARS-CoV-2-specific immune responsesJCI insight.  6. 2021
    2021 Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters 2021
    2021 Convalescent plasma-mediated resolution of COVID-19 in a patient with humoral immunodeficiency 2021
    2021 Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infectionJournal of Clinical Investigation.  131. 2021
    2020 Annals on call - A primer on COVID-19 vaccinesAnnals of Internal Medicine.  173. 2020
    2020 Mechanistic inferences from clinical reports of SARS-CoV-2 2020
    2020 Reply to Jakovac and to Rocha et al.: Can vitamin D prevent or manage COVID-19 illness? 2020
    2019 HLA-I Associated Adaptation Dampens CD8 T-Cell Responses in HIV Ad5-Vectored Vaccine RecipientsJournal of Infectious Diseases.  220:1620-1628. 2019
    2018 Short Communication: Apoptotic Membrane Microparticles Quantified by Fluorescent Bead-Based Assay Are Elevated in HIV and SIV InfectionsAIDS Research and Human Retroviruses.  34:446-448. 2018
    2018 Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populationsHuman Immunology.  79:166-171. 2018
    2018 Progressive lentivirus infection induces natural killer cell receptor-expressing B cells in the gastrointestinal tractAIDS.  32:1571-1578. 2018
    2018 Understanding the CD8 T-cell response in natural HIV control [version 1; referees: 3 approved]F1000Research.  7. 2018
    2017 CD151 expression is associated with a hyperproliferative T cell phenotypeJournal of Immunology.  199:3336-3347. 2017
    2017 CD4 + T cells from HIV-1 patients with impaired Th1 effector responses to Mycobacterium tuberculosis exhibit diminished histone and nucleoprotein signaturesClinical Immunology.  181:16-23. 2017
    2016 Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progressionJournal of Experimental Medicine.  213:2049-2063. 2016
    2016 HIV-1-specific CD8 T cells exhibit limited cross-reactivity during acute infectionJournal of Immunology.  196:3276-3286. 2016
    2016 Enhanced allogeneic cellular responses to mismatched HLA-B antigens results in more efficient killing of HIV infected cells 2016
    2016 Vaccination with heterologous HIV-1 envelope sequences and heterologous adenovirus vectors increases T-cell responses to conserved regions: HVTN 083Journal of Infectious Diseases.  213:541-550. 2016
    2015 Normal T-cell activation in elite controllers with preserved CD4 + T-cell countsAIDS.  29:2245-2254. 2015
    2015 Enhanced recognition of HIV-1 cryptic epitopes restricted by HLA Class I alleles associated with a favorable clinical outcome 2015
    2015 Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals.Journal of AIDS and Clinical Research.  6. 2015
    2014 Human Immunodeficiency Virus VaccinesInfectious Disease Clinics of North America.  28:615-631. 2014
    2014 Short communication: Plasmacytoid dendritic cells from HIV-1 elite controllers maintain a gut-homing phenotype associated with immune activationAIDS Research and Human Retroviruses.  30:1213-1215. 2014
    2014 Phase i/ii randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-Uninfected adult participants 2014
    2014 Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia ankara vaccines expressing HIV-1 virus-like particlesJournal of Infectious Diseases.  210:99-110. 2014
    2014 Characterization of T-Cell responses to cryptic epitopes in recipients of a noncodon-optimized HIV-1 Vaccine 2014
    2014 Effects of atorvastatin and pravastatin on immune activation and T-cell function in antiretroviral therapy-suppressed HIV-1-infected patientsAIDS.  28:2627-2631. 2014
    2013 Dimorphic HLA-B signal peptides differentially influence HLA-E- and natural killer cell-mediated cytolysis of HIV-1-infected target cellsClinical and Experimental Immunology.  174:414-423. 2013
    2013 Hormonal contraception and hiv-1 infection: Medroxyprogesterone acetate suppresses innate and adaptive immune mechanismsEndocrinology.  154:1282-1295. 2013
    2012 Host factor transcriptional regulation contributes to preferential expression of HIV type 1 in IL-4-producing CD4 T cellsJournal of Immunology.  189:2746-2757. 2012
    2012 Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in african americansHuman Molecular Genetics.  21:4334-4347. 2012
    2011 Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutatedJournal of Experimental Medicine.  208:2237-2249. 2011
    2011 Interleukin-2 production by polyfunctional HIV-1-specific CD8 T cells is associated with enhanced viral suppression 2011
    2011 Glycoprotein B vaccine is capable of boosting both antibody and CD4 T-cell responses to cytomegalovirus in chronically infected womenJournal of Infectious Diseases.  203:1534-1541. 2011
    2011 CD8 T-cell proliferative capacity is compromised in primary HIV-1 infection 2011
    2011 Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particlesJournal of Infectious Diseases.  203:610-619. 2011
    2010 CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcriptionJournal of Experimental Medicine.  207:51-59. 2010
    2009 Evolution of HLA-B 5703 hiv-1 escape mutations in HLA-B 5703-positive individuals and their transmission recipientsJournal of Experimental Medicine.  206:909-921. 2009
    2009 Safety and immunogenicity of adenovirus-vectored near-consensus HIV type 1 clade B gag vaccines in healthy adults.AIDS Research and Human Retroviruses.  25:103-114. 2009
    2008 Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipientsJournal of Experimental Medicine.  205:1009-1017. 2008
    2008 Treatment response in acute/early infection versus advanced AIDS: Equivalent first and second phases of HIV RNA declineAIDS.  22:957-962. 2008
    2007 Immunological control of chronic HIV-1 infection: HLA-mediated immune function and viral evolution in adolescentsAIDS.  21:2387-2397. 2007
    2007 Evaluation of cellular immune responses in subjects chronically infected with HIV type 1AIDS Research and Human Retroviruses.  23:67-76. 2007
    2007 Functionally competent antigen-specific Cd127hi memory CD8 + T cells are preserved only in HIV-infected individuals receiving early treatmentJournal of Infectious Diseases.  195:108-117. 2007
    2006 Preterm delivery and asthma: A systematic review and meta-analysisJournal of Allergy and Clinical Immunology.  118:823-830. 2006
    2006 Interleukin-2 reconstitutes defective human immunodeficiency virus (HIV), and cytomegalovirus (CMV) specific CD8+ T cell proliferation in HIV infectionJournal of Medical Virology.  78:1147-1157. 2006
    2006 HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsBlood.  107:4781-4789. 2006
    2006 HIV-1 epitope-specific CD8+ T cell responses strongly associated with delayed disease progression cross-recognize epitope variants efficientlyJournal of Immunology.  176:6130-6146. 2006
    2006 Group M-based HIV-1 Gag peptides are frequently targeted by T cells in chronically infected US and Zambian patientsAIDS.  20:353-360. 2006
    2005 High-dose recombinant canarypox vaccine expressing HIV-1 protein, in seronegative human subjectsJournal of Infectious Diseases.  192:1249-1259. 2005
    2005 Cutting edge: Emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell helpJournal of Immunology.  174:5926-5930. 2005
    2005 Increased levels of galactose-deficient IgG in sera of HIV-1-infected individualsAIDS.  19:381-389. 2005
    2005 Breast milk-derived antigen-specific CD8+ T cells: An extralymphoid effector memory cell population in humansJournal of Immunology.  174:2951-2956. 2005
    2005 CD8 T-cell responses in early HIV-1 infection are skewed towards high entropy peptidesAIDS.  19:241-250. 2005
    2004 Paucity of antigen-specific IgA responses in sera and external secretions of HIV-type 1-infected individualsAIDS Research and Human Retroviruses.  20:972-988. 2004
    2004 Absence of immunodominant anti-gag p17 (SL9) responses among gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 alleleJournal of Immunology.  173:2126-2133. 2004
    2004 Comparison of systemic and mucosal delivery of 2 canarypox virus vaccines expressing either HIV-1 genes or the gene for rabies virus G proteinJournal of Infectious Diseases.  189:1221-1231. 2004
    2003 T Cell Responses in HIV Type 1-Infected Adolescent Minorities Share Similar Epitope Specificities with Whites Despite Significant Differences in HLA Class I AllelesAIDS Research and Human Retroviruses.  19:1017-1026. 2003
    2003 Cross-reactive CD8+ T cell epitopes identified in US adolescent minorities 2003
    2003 Antigen burden is a major determinant of human immunodeficiency virus-specific CD8+ T cell maturation state: Potential implications for therapeutic immunizationJournal of Infectious Diseases.  187:364-374. 2003
    2003 The foamy virus envelope glycoproteinsCurrent Topics in Microbiology and Immunology.  277:111-129. 2003
    2002 Detection of mucosal antibodies in HIV type 1-infected individualsAIDS Research and Human Retroviruses.  18:1291-1300. 2002
    2002 Safety and immunogenicity of a high-titered canarypox vaccine in combination with rgp120 in a diverse population of HIV-1-uninfected adults: AIDS vaccine evaluation group protocol 022A 2002
    2001 CD8 CTL responses in vaccines: Emerging patterns of HLA restriction and epitope recognitionImmunology Letters.  79:37-45. 2001
    2001 Prognosis and risk evaluation in postoperative coronary patients: The PERISCOP study: Methodology and characteristics of the included population 2001
    2001 Cellular and humoral immune responses to a canarypox vaccine containing human immunodeficiency virus type 1 env, gag, and pro in combination with RGP120Journal of Infectious Diseases.  183:563-570. 2001
    2000 Recurrence of the acute HIV syndrome after interruption of antiretroviral therapy in a patient with chronic HIV infection: A case reportAnnals of Internal Medicine.  133. 2000
    2000 Cytokine profiles in seronegative volunteers immunized with a recombinant canarypox and gp120 prime-boost HIV-1 vaccineAIDS.  14:1365-1374. 2000
    1999 MN and IIIB recombinant glycoprotein 120 vaccine-induced binding antibodies to native envelope glycoprotein of human immunodeficiency virus type 1 primary isolatesAIDS Research and Human Retroviruses.  15:921-930. 1999
    1999 HIV- 1(MN) recombinant glycoprotein 160 vaccine-induced cellular and humoral immunity boosted by HIV-1(MN) recombinant glycoprotein 120 vaccineAIDS Research and Human Retroviruses.  15:115-132. 1999
    1996 Analysis of West African hunters for foamy virus infectionsAIDS Research and Human Retroviruses.  12:1725-1730. 1996
    1995 Identification of an ER retrieval signal in a retroviral glycoproteinCell.  82:543-544. 1995
    1995 An outbreak of Burkholderia (formerly Pseudomonas) cepacia respiratory tract colonization and infection associated with nebulized albuterol therapyAnnals of Internal Medicine.  122:762-766. 1995

    Chapter

    Year Title Altmetric
    2014 Human immunodeficiency viruses types 1 and 2.  1001-1062. 2014
    2002 Some Basic Cellular Immunology Principles applied to the Pathogenesis of Infectious Diseases 2002

    Principal Investigator On

  • A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults  awarded by Emory University
  • A Proof of Concept, Randomized, Controlled Study of Tuberculosis Immunization with BCG to Prevent Infection in Healthy Adults  awarded by Jackson (Henry M.) Foundation
  • A Rational Approach for HIV Vaccine T Cell Epitope Selection  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Analysis of Variant Epitope Specific CD8 T-Cells to Optimize HIV Vaccine Design  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Anthrax Human Clinical Trials Study Record Management  awarded by CDC - Centers for Disease Control and Prevention/DHHS
  • CHAVI - Center for HIV/AIDS Vaccine Immunology - CHAVI 012: Core B Mucosal and Immune Responses and Viral Reservoirs in Tissues and Cells During Acute HIV Infections  awarded by Duke University
  • COVID-19 Prevention Network (CoVPN) Site Preparation Funding - Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • CTL and HIV Polymorphisms in Heterosexual Transmission  awarded by Emory University
  • CTL and HIV Polymorphisms in Heterosexual Transmission  awarded by Emory University
  • Clincial Research Site Activities for the LTE to HVTN 117/HPX2004  awarded by Hutchinson (Fred) Cancer Research Center
  • CoVPN 3002 Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • CoVPN 3003 Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • CoVPN 3006 Protocol Funding (PF) - Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • Completed - Comprehensive Cancer Center Core Support Grant - DNA Sequencing SF  awarded by National Cancer Institute/NIH/DHHS
  • Defining the Biological Relevance of HIV Specific HLA-E Restricted CD8 T cell Responses  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Defining the Biological Relevance of HIV-1 Adaptation to CD4 T Cell Responses  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Effector and Regulatory Activities of HLA-E-Restricted HIV-Specific aBCD8 T Cells  awarded by UNIVERSITY OF TEXAS (EL PASO)
  • HIV Vaccine Trials Network Correlates Protocol Funding  awarded by Hutchinson (Fred) Cancer Research Center
  • HIV-1 Cryptic Epitopes: Implications for Vaccine Design  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • HPX3002/HVTN 706 Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding Year 14  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 405/HPTN 1901 Protocol Funding (PF) - Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 505 Protocol Implementation Funds  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 703/HPTN 081 Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 703/HPTN 081 Site Readiness  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 704/HPTN 085 Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN 704/HPTN 085 Protocol Funding (PF) - Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding (Pf): Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding Year 13  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Funding Year 16  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Protocol Implementation Funds  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Research and Mentorship Program (RAMP)  awarded by Hutchinson (Fred) Cancer Research Center
  • HVTN Research and Mentorship Program (RAMP)  awarded by Hutchinson (Fred) Cancer Research Center
  • HvTN Scientific Leadership - Co-Chair, Concept Working Group  awarded by Hutchinson (Fred) Cancer Research Center
  • Immunologic Uniqueness of the Female Genital Tract in HIV Pathogenesis - Clinical Core B  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Impact of Cross-Reactive CD8 T cells on HIV-1 Viral Control and Evolution  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Impact of HLA-II Adaptation on CD4 T-Cell and Tfh Responses in HIV-1 Vaccination  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Interleukin-21 Immune Mediated Control of HIV-1  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Mapping Novel Subdominant B*5701 Epitopes in Conserved Regions of the HIV Proteome  awarded by UNIVERSITY OF TEXAS
  • NIAID-Fred Hutch-Janssen Collaboration CTU/Clinical Trial Site Activities for HVTN 117/118  awarded by Hutchinson (Fred) Cancer Research Center
  • NIAID-Fred Hutch-Janssen Collaboration CTU/Clinical Trial Site Activities for HVTN 118/HPX2003 - Birmingham Clinical Research Site  awarded by Hutchinson (Fred) Cancer Research Center
  • Oxidative Stress and T Cell Balance: Effect on Pulmonary Tuberculosis During HIV  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS
  • Private Grant  awarded by TAIMED BIOLOGICS
  • Private Grant  awarded by VAXIN, INC.
  • Private Grant  awarded by HEMISPHERX BIOPHARMA, INC.
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group
  • Private Grant  awarded by SANOFI PASTEUR LIMITED
  • The Impact of HIV Adaptation to CD8 T Cells on Infection and Viral Control  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Core B - Developmental Core  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - DNA Sequencing  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Development Core  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Developmental Core B  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • VVTEU Protocol Development and Implementation for Task Areas B-C Phase II Vaccine Trial for Influenza (“Flu Pandemic” or “H7”)  awarded by VANDERBILT UNIVERSITY MEDICAL CENTER
  • Vaccine and Treatment Evaluation Units  awarded by VANDERBILT UNIVERSITY MEDICAL CENTER
  • Vaccine and Treatment Evaluation Units - Admin Task  awarded by VANDERBILT UNIVERSITY
  • Investigator On

  • (CSSC-001) Convalescent Plasma to Stem Coronavirus: A Randomized Controlled Double Blinded Phase 2 Study Comparing the Efficacy and Safety of Human Coronavirus Immune Plasma (HCIP) vs. control( SARS-CoV-2 non-immune plasma) among Adults Exposed to COVID-19 and (CSSC-004) Convalescent Plasma to Stem Coronavirus: A Randomized Controlled Double Blinded Phase 2 Study Comparing the Efficacy and Safety of Human Coronavirus Immune Plasma (HCIP) vs. Control (SARS-CoV-2 non-immune plasma)  awarded by Johns Hopkins University
  • A-Z Clinical Trials Unit  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Alabama - Clinical Trials Unit  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Alabama Clinical Trials Unit (CTU)  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Alabama Clinical Trials Unit (CTU)  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • CHAVI - Center for HIV/AIDS Vaccine Immunology  awarded by Duke University
  • Chimeric Adenoviruses for an Improved HIV Vaccine  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • CoVPN 5001 (Acute Immune Responses to SARS-CoV-2 Infection) Protocol Funding (PF)  awarded by Hutchinson (Fred) Cancer Research Center
  • Completed - Comprehensive Genomics Shared Facility - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Convalescent Plasma Randomized Clinical Trials for SARS-CoV-2 Prophylaxis and Early COVID-19 Treatment are Foundational for Subsequent Hyperimmune Globulin and Vaccines  awarded by Johns Hopkins University
  • Dynamics of the Protective Vaccine-Induced Human Influenza Neuraminidase B Cell Response  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • HPTN 083-A Phase 2b/3 Double Blind Safety and Efficacy Study of Injectable Cabotegravir Compared to Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine (TDF/FTC), For Pre-Exposure Prophylaxis in HIV-Uninfected Cisgender Men and Transgender Women who have Sex with Men  awarded by FAMILY HEALTH INTERNATIONAL
  • High VS. Standard Dose Flu Vaccine in Adult Stem Cell Transplant Recipients  awarded by VANDERBILT UNIVERSITY
  • IL-21 and Immune Mediated Viral Control  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Immunologic Uniqueness of the Female Genital Tract in HIV Pathogenesis  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Kinomic Analysis of Host Cell Factors Controlling Latent HIV-1 Infection  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Kinomic Analysis of Host Cell Factors Controlling Latent HIV-1 Infection  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Leadership Group for the Infectious Diseases Clinical Research Consortium (IDCRCLG) COVID 19 SUPPLEMENT  awarded by Emory University
  • Mechanisms and Correlates of Immune Protection Against Genital Chlamydia in Humans  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Private Grant  awarded by Gilead Sciences ^
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by Gilead Sciences ^
  • Private Grant  awarded by BAVARIAN NORDIC A/S
  • Private Grant  awarded by VICAL, INC.
  • Private Grant  awarded by BAVARIAN NORDIC A/S
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by GENECURE BIOTECHNOLOGIES, LLC
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by Gilead Sciences ^
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by VICAL, INC.
  • Private Grant  awarded by GENOCEA BIOSCIENCES, INC.
  • Private Grant  awarded by PROTEUS DIGITAL HEALTH, INC.
  • Private Grant  awarded by GlaxoSmithKline
  • Private Grant  awarded by Gilead Sciences ^
  • Private Grant  awarded by BAVARIAN NORDIC A/S
  • Private Grant  awarded by Gilead Sciences ^
  • Private Grant  awarded by GlaxoSmithKline
  • Private Grant  awarded by REGENERON PHARMACEUTICALS, INC.
  • Survival Factors Regulating the HIV-Specific Cytotoxic T Lymphocyte Response  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • The Origin and Future Protective Activity of SARS-CoV-2 RBD Specific Neutralizing Antibodies  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research (CFAR)  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Administrative Core  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Administrative Core  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • UAB Center for AIDS Research - Administrative Supplement  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Vaccine and Treatment Evaluation Units  awarded by VANDERBILT UNIVERSITY MEDICAL CENTER
  • Viral Adaptation to CD4 T Cell Responses and the Impact on HIV Immunity  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Virus-Induced Cell Fate Decisions in Anti-Viral Immunity  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Virus-induced Cell Fate Decisions in Anti-Viral Immunity - Administrative Supplement  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS
  • Education And Training

  • UAB Hospital, Internship
  • UAB Hospital, Residency
  • UAB Hospital, Postdoctoral Fellowship
  • Doctor of Medicine, Baylor College of Medicine 1991
  • Full Name

  • Paul Goepfert