Nabiha Yusuf Ph.D.

Nabiha Yusuf Ph.D.
Professor

Senior Scientist (C), UAB Immunology Institute , School of Medicine
Scientist (C), UWIRC Microbiome Center , School of Medicine
Scientist (C), Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC) , School of Medicine
Scientist (C), O'Neal Comprehensive Cancer Center , School of Medicine
Professor (P), Dermatology , School of Medicine
Scientist, Cancer Chemoprevention , O'Neal Comprehensive Cancer Center
Associate Scientist (C), Center for Clinical and Translational Science (CCTS) , General Clinical Research Center
Scientist (C), Global Center for Craniofacial, Oral and Dental Disorders (GC-CODED) , School of Dentistry
Associate Professor (S), Epidemiology , School of Public Health

Selected Publications

Academic Article

Year	Title	Altmetric
2022	Editorial: Environment and Skin Cancer. Frontiers in Oncology. 12. 2022
2022	Type I Interferons Enhance the Repair of Ultraviolet Radiation-Induced DNA Damage and Regulate Cutaneous Immune Suppression. International Journal of Molecular Sciences. 23. 2022
2022	Phytocompounds from the Medicinal and Dietary Plants: Multi-target Agents for Cervical Cancer Prevention and Therapy. Current Medicinal Chemistry. 29:4481-4506. 2022
2021	Hidradenitis suppurativa: pathogenesis, clinical presentation, epidemiology, and comorbid associations. International Journal of Dermatology. 60:e449-e458. 2021
2021	Toll-like receptor-4 antagonist enhances the repair of ultraviolet radiation-induced DNA damage and augments anti-tumor immune responses in mice. Cancers. 13. 2021
2021	Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells. Frontiers in Pharmacology. 12. 2021
2021	Regulatory T Cells Play an important role in the prevention of Murine Melanocytic Nevi and Melanomas. Cancer Prevention Research. 14:165-174. 2021
2021	IL-23 and the Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1290:89-98. 2021
2021	Toll-like receptor-4 deficiency inhibits ultraviolet radiation-induced tumor development by modulation of immune and inflammatory responses. Molecular Carcinogenesis. 60:60-70. 2021
2020	Murine Skin Carcinogenesis and the Role of Immune System Dysregulation in the Tumorigenicity of 2-Ethylhexyl Acrylate.. Biomedicine Hub. 5:958-973. 2020
2020	The Cutaneous Manifestations Associated with COVID-19: A review. 2020
2019	KSRP modulates melanoma growth and efficacy of vemurafenib 2019
2019	A novel marine natural product derived pyrroloiminoquinone with potent activity against skin cancer cells. Marine Drugs. 17. 2019
2019	Protective Effect of Baicalin Against TLR4-mediated UVA-induced Skin Inflammation. Photochemistry and Photobiology. 95:605-611. 2019
2019	Ultraviolet radiation, both UVA and UVB, influences the composition of the skin microbiome. Experimental Dermatology. 28:136-141. 2019
2018	Peptide-Functionalized Hydrogel Cubes for Active Tumor Cell Targeting. Biomacromolecules. 19:4084-4097. 2018
2018	Cancer Therapy-Induced Cardiovascular Toxicity: Doxorubicin triggers splenic contraction and irreversible dysregulation of cox and lox that alters the inflammation-resolution program in the myocardium 2018
2018	Inhibition of interleukin-12 and/or interleukin-23 for the treatment of psoriasis: What is the evidence for an effect on malignancy?. Experimental Dermatology. 27:737-747. 2018
2018	The skin microbiome and immune system: Potential target for chemoprevention? 2018
2017	Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis. Scientific Reports. 7. 2017
2017	Loss of INK4a/Arf gene enhances ultraviolet radiation-induced cutaneous tumor development. Experimental Dermatology. 26:1018-1025. 2017
2017	Association of vitamin D receptor polymorphisms with the risk of nonmelanoma skin cancer in adults. JAMA Dermatology. 153:983-989. 2017
2017	An epigenome-wide association study of inflammatory response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network. Pharmacogenomics. 18:1333-1341. 2017
2017	Ultraviolet Radiation-Induced Downregulation of SERCA2 Mediates Activation of NLRP3 Inflammasome in Basal Cell Carcinoma. Photochemistry and Photobiology. 93:1025-1033. 2017
2017	Proteomic Analysis and Functional Studies of Baicalin on Proteins Associated with Skin Cancer 2017
2016	A murine model for the development of melanocytic nevi and their progression to melanoma. Molecular Carcinogenesis. 55:646-658. 2016
2015	Baicalin Protects Keratinocytes from Toll-like Receptor-4 Mediated DNA Damage and Inflammation Following Ultraviolet Irradiation. Photochemistry and Photobiology. 91:1435-1443. 2015
2015	P-selectin enhances growth and metastasis of mouse mammary tumors by promoting regulatory T cell infiltration into the tumors. Life Sciences. 131:11-18. 2015
2015	In vivo suppression of heat shock protein (HSP)27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemical. Journal of Immunology. 194:4796-4803. 2015
2015	Erratum: Vitamin D and skin cancer (Photochemistry and Photobiology 91:1 (204) 10.1111/php.12382). Photochemistry and Photobiology. 91:766. 2015
2015	Interleukin-17 mediated inflammatory responses are required for ultraviolet radiation-induced immune suppression. Photochemistry and Photobiology. 91:235-241. 2015
2015	Vitamin D and skin cancer. Photochemistry and Photobiology. 91:201-209. 2015
2014	Type i interferons: Key players in normal skin and select cutaneous malignancies. Dermatology Research and Practice. 2014. 2014
2014	The effects of baicalin against UVA-induced photoaging in skin fibroblasts 2014
2014	Toll-like receptor mediated regulation of breast cancer: A case of mixed blessings. Frontiers in Immunology. 5. 2014
2014	Toll-like receptor-4 deficiency enhances repair of UVR-induced cutaneous DNA damage by nucleotide excision repair mechanism. Journal of Investigative Dermatology. 134:1710-1717. 2014
2014	Toll-like receptors and skin cancer. Frontiers in Immunology. 5. 2014
2013	Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome. Toxicology and Applied Pharmacology. 270:70-76. 2013
2012	Biological properties of carbon powders synthesized using chemical vapour deposition and detonation methods. Journal of Nanoscience and Nanotechnology. 12:9037-9046. 2012
2012	Tualang honey protects keratinocytes from ultraviolet radiation-induced inflammation and DNA damage. Photochemistry and Photobiology. 88:1198-1204. 2012
2012	IL-17 mediated inflammation promotes tumor growth and progression in the skin. PLoS One. 7. 2012
2012	Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice. International Journal of Cancer. 130:765-774. 2012
2012	Expression of toll-like receptors on breast tumors: taking a toll on tumor microenvironment.. International Journal of Breast Cancer. 2012:716564. 2012
2011	The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma. International Journal of Dermatology. 50:1223-1233. 2011
2011	Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by Toll-like receptor-4. Molecular cell biology research communications : MCBRC. 508:171-177. 2011
2011	Differential roles of T-cell subsets in regulation of ultraviolet radiation induced cutaneous photocarcinogenesis. Photochemistry and Photobiology. 87:387-398. 2011
2010	IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. Journal of Immunology. 184:2281-2288. 2010
2009	IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation. Carcinogenesis. 30:1970-1977. 2009
2009	Resveratrol enhances cell-mediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesis. Molecular Carcinogenesis. 48:713-723. 2009
2009	Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity. Journal of Immunology. 182:675-683. 2009
2008	Antagonistic roles of CD4⁺ and CD8⁺ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis. Cancer Research. 68:3924-3930. 2008
2008	Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis (Cancer Research (2008) 68, (615-622)). Cancer Research. 68:1609. 2008
2008	The immunosuppressive effects of phthalocyanine photodynamic therapy in mice are mediated by CD4⁺ and CD8⁺ T cells and can be adoptively transferred to naive recipients. Photochemistry and Photobiology. 84:366-370. 2008
2008	Protective role of toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis. Cancer Research. 68:615-622. 2008
2007	Acquired and innate immunity to polyaromatic hydrocarbons. Toxicology and Applied Pharmacology. 224:308-312. 2007
2007	Photoprotective effects of green tea polyphenols 2007
2006	Suppression of Mycobacterium tuberculosis induced reactive oxygen species (ROS) and TNF-α mRNA expression in human monocytes by allicin. FEBS Letters. 580:2517-2522. 2006
2004	Topical application of dimethylbenz[a]anthracene results in the generation of multiple melanocytic nevi in C3H/HeN mice. Toxicology and Applied Pharmacology. 195:355-360. 2004
2004	Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugs. 2004
2003	Comparative proteomic profiling of murine skin. Journal of Investigative Dermatology. 121:51-64. 2003

Chapter

Year	Title	Altmetric
2022	Herbal medicines and skin disorders. 307-328. 2022
2017	UV and skin: Photocarcinogenesis. 67-103. 2017
2011	Systemic and topical use of green tea polyphenols for healthy skin. 71-83. 2011
2005	Photoprotection by green tea polyphenols. 639-656. 2005