Selected Publications

Academic Article

Year Title Altmetric
2020 Role for ovarian hormones in purinoceptor-dependent natriuresisBiology of Sex Differences.  11. 2020
2020 High molecular weight kininogen contributes to early mortality and kidney dysfunction in a mouse model of sickle cell diseaseJournal of Thrombosis and Haemostasis.  18:2329-2340. 2020
2020 Diurnal Control of Blood Pressure Is Uncoupled from Sodium ExcretionHypertension.  75:1624-1634. 2020
2020 Sex differences in the trajectory of glomerular filtration rate in pediatric and murine sickle cell anemiaBlood Advances.  4:263-265. 2020
2020 Loss of endothelin type B receptor function improves insulin sensitivity in ratsCanadian Journal of Physiology and Pharmacology.  98:604-610. 2020
2019 Impact of ET-1 and sex in glomerular hyperfiltration in humanized sickle cell miceClinical Science.  133:1475-1486. 2019
2019 Dynamic changes in histone deacetylases following kidney ischemia-reperfusion injury are critical for promoting proximal tubule proliferation 2019
2019 Tauroursodeoxycholic acid (TUDCA) abolishes chronic high salt-induced renal injury and inflammation 2019
2019 Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathyAmerican Journal of Hematology.  94:417-423. 2019
2019 Combined hydroxyurea and ET A receptor blockade reduces renal injury in the humanized sickle cell mouse 2019
2019 Hyperfiltration predicts long-term renal outcomes in humanized sickle cell miceBlood Advances.  3:1460-1475. 2019
2018 A more direct way to measure glomerular albumin permeability—even in human glomeruli!Kidney International.  93:1035-1037. 2018
2018 Diurnal pattern in skin Na+and water content is associated with salt-sensitive hypertension in ETBreceptor-deficient rats 2018
2018 High dietary sodium causes dyssynchrony of the renal molecular clock in rats 2018
2017 Renal denervation attenuates hypertension but not salt sensitivity in ETB receptor-deficient rats 2017
2017 Interplay between renal endothelin and purinergic signaling systems 2017
2017 Long-term endothelin-a receptor antagonism provides robust renal protection in humanized sickle cell disease miceJournal of the American Society of Nephrology.  28:2443-2458. 2017
2017 Ovariectomy uncovers purinergic receptor activation of endothelin-dependent natriuresis 2017
2017 Insulin increases filtration barrier permeability via TRPC6-dependent activation of PKGIα signaling pathways 2017
2016 Endothelin receptor antagonists in sickle cell disease: A promising new therapeutic approachLife Sciences.  159:15-19. 2016
2016 Activation of purinergic receptors (P2) in the renal medulla promotes endothelin-dependent natriuresis in male rats 2016
2016 Extracellular purines’ action on glomerular albumin permeability in isolated rat glomeruli: Insights into the pathogenesis of albuminuria 2016
2016 Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathwayFEBS Letters.  1739-1748. 2016
2016 Involvement of P2 receptors in regulation of glomerular permeability to albumin by extracellular nucleotides of intra-/extra-glomerular originsJournal of Physiology and Pharmacology.  67:177-183. 2016
2016 Endothelin-1 and the kidney: New perspectives and recent findingsCurrent Opinion in Nephrology and Hypertension.  25:35-41. 2016
2015 Insulin increases glomerular filtration barrier permeability through PKGIα-dependent mobilization of BKCa channels in cultured rat podocytes 2015
2013 Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits 2013

Education And Training

  • Doctor of Philosophy Level Degree in Medical Scientist, Medical University of Gda?sk 2014
  • Full Name

  • Malgorzata Kasztan