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Malgorzata Kasztan
Instructor
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E-mail
mkasztan@uab.edu
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Malgorzata Kasztan
Instructor
Positions
Instructor (P)
,
Medicine - Nephrology
,
Department of Medicine
2019 -
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
2019 -
Publications
Research
Background
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Publications
Selected Publications
Academic Article
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Year
Title
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2020
Role for ovarian hormones in purinoceptor-dependent natriuresis
.
Biology of Sex Differences
. 11.
2020
2020
High molecular weight kininogen contributes to early mortality and kidney dysfunction in a mouse model of sickle cell disease
.
Journal of Thrombosis and Haemostasis
. 18:2329-2340.
2020
2020
Diurnal Control of Blood Pressure Is Uncoupled from Sodium Excretion
.
Hypertension
. 75:1624-1634.
2020
2020
Sex differences in the trajectory of glomerular filtration rate in pediatric and murine sickle cell anemia
.
Blood Advances
. 4:263-265.
2020
2020
Loss of endothelin type B receptor function improves insulin sensitivity in rats
.
Canadian Journal of Physiology and Pharmacology
. 98:604-610.
2020
2019
Impact of ET-1 and sex in glomerular hyperfiltration in humanized sickle cell mice
.
Clinical Science
. 133:1475-1486.
2019
2019
Dynamic changes in histone deacetylases following kidney ischemia-reperfusion injury are critical for promoting proximal tubule proliferation
2019
2019
Tauroursodeoxycholic acid (TUDCA) abolishes chronic high salt-induced renal injury and inflammation
2019
2019
Hyperfiltration during early childhood precedes albuminuria in pediatric sickle cell nephropathy
.
American Journal of Hematology
. 94:417-423.
2019
2019
Combined hydroxyurea and ET
A
receptor blockade reduces renal injury in the humanized sickle cell mouse
2019
2019
Hyperfiltration predicts long-term renal outcomes in humanized sickle cell mice
.
Blood Advances
. 3:1460-1475.
2019
2018
A more direct way to measure glomerular albumin permeability—even in human glomeruli!
.
Kidney International
. 93:1035-1037.
2018
2018
Diurnal pattern in skin Na
+
and water content is associated with salt-sensitive hypertension in ET
B
receptor-deficient rats
2018
2018
High dietary sodium causes dyssynchrony of the renal molecular clock in rats
2018
2017
Renal denervation attenuates hypertension but not salt sensitivity in ET
B
receptor-deficient rats
2017
2017
Interplay between renal endothelin and purinergic signaling systems
2017
2017
Long-term endothelin-a receptor antagonism provides robust renal protection in humanized sickle cell disease mice
.
Journal of the American Society of Nephrology
. 28:2443-2458.
2017
2017
Ovariectomy uncovers purinergic receptor activation of endothelin-dependent natriuresis
2017
2017
Insulin increases filtration barrier permeability via TRPC6-dependent activation of PKGIα signaling pathways
2017
2016
Endothelin receptor antagonists in sickle cell disease: A promising new therapeutic approach
.
Life Sciences
. 159:15-19.
2016
2016
Activation of purinergic receptors (P2) in the renal medulla promotes endothelin-dependent natriuresis in male rats
2016
2016
Extracellular purines’ action on glomerular albumin permeability in isolated rat glomeruli: Insights into the pathogenesis of albuminuria
2016
2016
Intracellular calcium signaling regulates glomerular filtration barrier permeability: the role of the PKGIα-dependent pathway
.
FEBS Letters
. 1739-1748.
2016
2016
Involvement of P2 receptors in regulation of glomerular permeability to albumin by extracellular nucleotides of intra-/extra-glomerular origins
.
Journal of Physiology and Pharmacology
. 67:177-183.
2016
2016
Endothelin-1 and the kidney: New perspectives and recent findings
.
Current Opinion in Nephrology and Hypertension
. 25:35-41.
2016
2015
Insulin increases glomerular filtration barrier permeability through PKGIα-dependent mobilization of BK
Ca
channels in cultured rat podocytes
2015
2013
Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits
2013
Research
Principal Investigator On
The Role Of Endothelin-1 In Tubular Injury In Sickle Cell Disease
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
2019 - 2021
The Role of ET-1 in Tubular Injury in Sickle Cell Disease
awarded by
American Heart Association
2019
Investigator On
Kidney Undergraduate Research Experience (KURE)
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
2018 - 2023
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
2017 - 2022
Integrating Novel Mechanisms Controlling Sodium Excretion and Blood Pressure - Project 1 = Circadian Control of Sodium Excretion
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
2017 - 2022
The Role of Endothelin in Sickle Cell Nephropathy
awarded by
ASN FOUNDATION FOR KIDNEY RESEARCH
2016 - 2018
Background
Education And Training
Doctor of Philosophy Level Degree in Medical Scientist,
Medical University of Gda?sk
2014
Contact
Full Name
Malgorzata
Kasztan