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Mary Sewell-Loftin
Assistant Professor
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E-mail
mksewellloftin@uab.edu
mksewellloftin@uab.edu
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Mary Sewell-Loftin
Assistant Professor
Positions
Associate Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
2020 -
Assistant Professor (P)
,
Dept of Biomedical Engineering
,
Academic Joint Departments
2020 -
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2020
Micro-strains in the extracellular matrix induce angiogenesis
2020
2019
Loss of flow responsive Tie1 results in Impaired
Aortic valve remodeling
.
Developmental Biology
. 455:73-84.
2019
2017
Cancer-associated fibroblasts support vascular growth through mechanical force
.
Scientific Reports
. 7.
2017
2017
Proteomic Alterations Associated with Biomechanical Dysfunction are Early Processes in the Emilin1 Deficient Mouse Model of Aortic Valve Disease
.
Annals of Biomedical Engineering
. 45:2548-2562.
2017
2015
Notch1 mutation leads to valvular calcification through enhanced myofibroblast mechanotransduction
2015
2014
Myocardial contraction and hyaluronic acid mechanotransduction inepithelial-to-mesenchymal transformation of endocardial cells
.
Biomaterials
. 35:2809-2815.
2014
2013
Cadherin-11 regulates cell-cell tension necessary for calcific nodule formation by valvular myofibroblasts
2013
2012
A novel technique for quantifying mouse heart valve leaflet stiffness with atomic force microscopy
2012
2011
EMT-inducing biomaterials for heart valve engineering: Taking cues from developmental biology
.
Journal of Cardiovascular Translational Research
. 4:658-671.
2011
2011
Sensing and modulation of invadopodia across a wide range of rigidities
.
Biophysical Journal
. 100:573-582.
2011
Chapter
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Year
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2018
Building better tumor models: Organoid systems to investigate angiogenesis
. 117-148.
2018
Research
Principal Investigator On
Biomechanical Regulation of Angiogenesis during Tumor Progression
awarded by
National Cancer Institute/NIH/DHHS
2020 - 2023
Teaching
Teaching Activities
BME401 - Undergraduate BME Seminar (Fall Term 2020)
2020
BME496 - BME Honors Seminar (Fall Term 2020)
2020
BME601 - Biomedical Engineering Seminar (Fall Term 2020)
2020
BME698 - Non-Thesis Research (Fall Term 2020)
2020
BME701 - Biomedical Engineering Seminar (Fall Term 2020)
2020
Background
Education And Training
Doctor of Philosophy in Biomedical / Medical Engineering,
Vanderbilt University
2014
Contact
Full Name
Mary
Sewell-Loftin