Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Meeting report and review: Immunological assays and correlates of protection for next-generation influenza vaccines 2020
2019 Heterologous prime-boost with A(H5N1) pandemic influenza vaccines induces broader cross-clade antibody responses than homologous prime-boost 2019
2019 Insights into the antigenic advancement of influenza A(H3N2) viruses, 2011–2018 2019
2019 Repeated vaccination against matched H3N2 influenza virus gives less protection than single vaccination in ferrets 2019
2019 Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial among Preschool-Aged Children in Urban Bangladesh 2019
2019 The Effect of Preexisting Immunity on Virus Detection and Immune Responses in a Phase II, Randomized Trial of a Russian-Backbone, Live, Attenuated Influenza Vaccine in Bangladeshi Children 2019
2019 Update: Influenza activity — United States, september 30, 2018–february 2, 2019 2019
2019 Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons 2019
2018 Influenza activity — United States, September 30–December 1, 2018 2018
2018 Cell culture-derived influenza vaccines in the severe 2017–2018 epidemic season: a step towards improved influenza vaccine effectiveness 2018
2018 Update: Influenza activity — United States and worldwide, May 20–October 13, 2018 2018
2018 Influence of Immune Priming and Egg Adaptation in the Vaccine on Antibody Responses to Circulating A(H1N1)pdm09 Viruses after Influenza Vaccination in Adults 2018
2018 Human infection with avian influenza A(H7N2) virus—Virginia, 2002 2018
2018 Update: Influenza activity in the united states during the 2017–18 season and composition of the 2018–19 influenza vaccine 2018
2018 Development of a high-throughput assay to detect antibody inhibition of low pH induced conformational changes of influenza virus hemagglutinin 2018
2018 Kinetics of Serological Responses in Critically Ill Patients Hospitalized with 2009 Pandemic Influenza A(H1N1) Virus Infection in Canada, 2009-2011 2018
2018 Update: Influenza activity - United States, October 1, 2017-February 3, 2018 2018
2018 Evaluating interest in an influenza A(H5N1) vaccine among laboratory workers who work with highly-pathogenic avian influenza viruses in the United States 2018
2017 Pathogenicity testing of influenza candidate vaccine viruses in the ferret model 2017
2017 Update: Influenza activity — United States and worldwide, may 21-september 23, 2017 2017
2017 Infection with influenza A(H1N1)pdm09 during the first wave of the 2009 pandemic: Evidence from a longitudinal seroepidemiologic study in Dhaka, Bangladesh 2017
2017 Phenotype and function of myeloidderived suppressor cells induced by Porphyromonas gingivalis infection 2017
2017 Stockpiled pre-pandemic H5N1 influenza virus vaccines with AS03 adjuvant provide cross-protection from H5N2 clade 2.3.4.4 virus challenge in ferrets 2017
2017 CBirTox is a selective antigen-specific agonist of the Treg-IgA-microbiota homeostatic pathway 2017
2017 Update: Influenza activity in the United States during the 2016–17 season and composition of the 2017–18 influenza vaccine 2017
2017 Nasal delivery of Protollin-adjuvanted H5N1 vaccine induces enhanced systemic as well as mucosal immunity in mice 2017
2017 Novel influenza A viruses and pandemic threats 2017
2017 Evaluation of multiplex assay platforms for detection of influenza hemagglutinin subtype specific antibody responses 2017
2017 Novel multiplex assay platforms to detect influenza A hemagglutinin subtype-specific antibody responses for high-throughput and in-field applications 2017
2017 Increase in human infections with avian influenza a(H7N9) virus during the fifth Epidemic – China, October 2016–February 2017 2017
2017 Improving the selection and development of influenza vaccine viruses – Report of a WHO informal consultation on improving influenza vaccine virus selection, Hong Kong SAR, China, 18–20 November 2015 2017
2017 Update: Influenza activity — United States, October 2, 2016–February 4, 2017 2017
2017 A pyrosequencing-based approach to high-throughput identification of influenza A(H3N2) virus clades harboring antigenic drift variants 2017
2017 CONSISE statement on the reporting of Seroepidemiologic Studies for influenza (ROSES-I statement): an extension of the STROBE statement 2017
2017 Cross-reactive antibody responses to novel h5nx influenza viruses following homologous and heterologous prime-boost vaccination with a prepandemic stockpiled a(h5n1) vaccine in humans 2017
2017 Effect of priming with seasonal influenza a(h3n2) virus on the prevalence of cross-reactive hemagglutination-inhibition antibodies to swine-origin a(h3n2) variants 2017
2017 Mild respiratory illness among young children caused by highly pathogenic avian influenza a (h5n1) virus infection in Dhaka, Bangladesh, 2011 2017
2017 Update: Increase in human infections with novel Asian lineage avian influenza a(h7n9) viruses during the fifth epidemic - China, October 1, 2016-August 7, 2017 2017
2017 Update: Influenza activity — United States, October 1–November 25, 2017 2017
2016 Update: Influenza activity — United States, October 2-December 17, 2016 2016
2016 Seasonal influenza vaccination of children induces humoral and cell-mediated immunity beyond the current season: Cross-reactivity with past and future strains 2016
2016 An oil-in-water nanoemulsion enhances immunogenicity of H5N1 vaccine in mice 2016
2016 Update: Influenza activity — United States and worldwide, May 22-September 10, 2016 2016
2016 Influenza activity - United States, 2015-16 season and composition of the 2016-17 influenza vaccine 2016
2016 Selection of antigenically advanced variants of seasonal influenza viruses 2016
2016 A cationic liposome-DNA complexes adjuvant (JVRS-100) enhances the immunogenicity and cross-protective efficacy of pre-pandemic influenza A (H5N1) vaccine in ferrets 2016
2016 Vaccination with 2014-15 Seasonal Inactivated Influenza Vaccine Elicits Cross-Reactive Anti-HA Antibodies with Strong ADCC Against Antigenically Drifted Circulating H3N2 Virus in Humans 2016
2016 A large proportion of the mexican population remained susceptible to A(H1N1) pdm09 infection one year after the emergence of 2009 influenza pandemic 2016
2016 Update: Influenza activity — United states, october 4, 2015–february 6, 2016 2016
2016 Effects of Repeated Annual Inactivated Influenza Vaccination among Healthcare Personnel on Serum Hemagglutinin Inhibition Antibody Response to A/Perth/16/2009 (H3N2)-like virus during 2010-11 2016
2016 A highly immunogenic vaccine against A/H7N9 influenza virus 2016
2016 NADPH oxidase 1 is associated with altered host survival and T cell phenotypes after influenza A virus infection in mice 2016
2016 Randomized controlled trial to compare immunogenicity of standard-dose intramuscular versus intradermal trivalent inactivated influenza vaccine in HIV-infected men who have sex with men in Bangkok, Thailand 2016
2016 Comparability of neuraminidase inhibition antibody titers measured by enzyme-linked lectin assay (ELLA) for the analysis of influenza vaccine immunogenicity 2016
2016 Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins 2016
2015 IL-1R/TLR2 through MyD88 divergently modulates osteoclastogenesis through regulation of nuclear factor of activated T cells c1 (NFATc1) and B lymphocyte-induced maturation protein-1 (Blimp1) 2015
2015 Update: Influenza activity — United States, October 4–November 28, 2015 2015
2015 Diverse antigenic site targeting of influenza hemagglutinin in the murine antibody recall response to A(H1N1)pdm09 virus 2015
2015 Increased Dietary Salt Intake Does Not Influence Influenza A Virus-Induced Disease Severity in Mice 2015
2015 Live animal markets in Minnesota: A potential source for emergence of novel influenza a viruses and interspecies transmission 2015
2015 Update: Influenza activity — United States and worldwide, may 24–September 5, 2015 2015
2015 Strengthening the influenza vaccine virus selection and development process. Report of the 3rd WHO Informal Consultation for Improving Influenza Vaccine Virus Selection held at WHO headquarters, Geneva, Switzerland, 1-3 April 2014. 2015
2015 International laboratory comparison of influenza microneutralization assays for A(H1N1)pdm09, A(H3N2), and A(H5N1) influenza viruses by CONSISE 2015
2015 AS03-adjuvanted H7N1 detergent-split virion vaccine is highly immunogenic in unprimed mice and induces cross-reactive antibodies to emerged H7N9 and additional H7 subtypes 2015
2015 Community-acquired pneumonia requiring hospitalization among U.S. adults 2015
2015 Oseltamivir inhibits influenza virus replication and transmission following ocular-only aerosol inoculation of ferrets 2015
2015 Comparison of traditional intranasal and aerosol inhalation inoculation of mice with influenza A viruses 2015
2015 Environmental conditions affect exhalation of H3N2 seasonal and variant influenza viruses and respiratory droplet transmission in ferrets 2015
2015 Assessment of transmission, pathogenesis and adaptation of H2 subtype influenza viruses in ferrets 2015
2015 NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection 2015
2015 Community-acquired pneumonia requiring hospitalization among U.S. children 2015
2015 A newly emerged swine-origin influenza a(H3N2) variant dampens host antiviral immunity but induces potent inflammasome activation 2015
2015 A(H7N9) virus results in early induction of proinflammatory cytokine responses in both human lung epithelial and endothelial cells and shows increased human adaptation compared with avian H5N1 Virus 2015
2015 Antibody to influenza virus neuraminidase: An independent correlate of protection 2015
2015 Emergence of highly pathogenic avian influenza A(H5N1) virus PB1-F2 variants and their virulence in BALB/c mice 2015
2015 Highly pathogenic avian influenza a(H5n1) virus infection among workers at live bird markets, Bangladesh, 2009–2010 2015
2015 Influenza activity — United states, 2014–15 season and composition of the 2015–16 influenza vaccine 2015
2015 Preexisting immunity, more than aging, influences influenza vaccine responses 2015
2015 Update: Influenza activity-United States, September 28, 2014–February 21, 2015 2015
2014 Use of highly pathogenic avian influenza A(H5N1) gain-of-function studies for molecular-based surveillance and pandemic preparedness 2014
2014 Improved specificity and reduced subtype cross-reactivity for antibody detection by ELISA using globular head domain recombinant hemagglutinin 2014
2014 Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins 2014
2014 Influenza vaccination accelerates recovery of ferrets from lymphopenia 2014
2014 Impact of immunosuppression on recall immune responses to influenza vaccination in stable renal transplant recipients 2014
2014 Safety and immunogenicity of a plant-produced recombinant monomer hemagglutinin-based influenza vaccine derived from influenza A (H1N1)pdm09 virus: A Phase 1 dose-escalation study in healthy adults 2014
2014 Update: Influenza activity - United States, September 29, 2013-February 8, 2014 2014
2014 Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship 2014
2014 Characterizing wild bird contact and seropositivity to highly pathogenic avian influenza A (H5N1) virus in Alaskan residents 2014
2014 Diversity of the murine antibody response targeting influenza A(H1N1pdm09) hemagglutinin 2014
2014 Effect of receptor binding specificity on the immunogenicity and protective efficacy of influenza virus A H1 vaccines 2014
2014 Evaluation of the antigenic relatedness and cross-protective immunity of the neuraminidase between human influenza A (H1N1) virus and highly pathogenic avian influenza A (H5N1) virus 2014
2014 IgM, IgG, and IgA antibody responses to influenza A(H1N1)pdm09 hemagglutinin in infected persons during the first wave of the 2009 pandemic in the United States 2014
2014 Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α-actinin-4 for viral replication 2014
2014 Influenza virus infectivity and virulence following ocular-only aerosol inoculation of ferrets 2014
2014 Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine 2014
2014 Molecular determinants of influenza virus pathogenesis in mice 2014
2014 Seroincidence of influenza among HIV-infected and HIV-uninfected men during the 2009 H1N1 influenza pandemic, Bangkok, Thailand 2014
2014 Serologic evidence of influenza A(H1N1) pdm09 virus infection in northern sea otters 2014
2014 Serum antibody response to matrix protein 2 following natural infection with 2009 pandemic influenza A(H1N1) virus in humans 2014
2013 Beta-defensin 2 enhances immunogenicity and protection of an adenovirus-based H5N1 influenza vaccine at an early time 2013
2013 Immune responses to infection with H5N1 influenza virus 2013
2013 Role of mTOR downstream effector signaling molecules in Francisella tularensis internalization by murine macrophages 2013
2013 Impact of prior seasonal H3N2 influenza vaccination or infection on protection and transmission of emerging variants of influenza A(H3N2)v virus in ferrets 2013
2013 Update: Influenza activity - United States, September 29-December 7, 2013 2013
2013 Severe acute respiratory infections caused by 2009 pandemic influenza A (H1N1) among American Indians-southwestern United States, May 1-July 21, 2009 2013
2013 Adenoviral vector expressing murine β-defensin 2 enhances immunogenicity of an adenoviral vector based H5N1 influenza vaccine in aged mice 2013
2013 Cytokine and chemokine profiles in lung tissues from fatal cases of 2009 pandemic influenza A (H1N1): Role of the host immune response in pathogenesis 2013
2013 Seroprevalence of Antibodies against Highly Pathogenic Avian Influenza A (H5N1) Virus among Poultry Workers in Bangladesh, 2009 2013
2013 Improving influenza vaccine virus selection: Report of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010 2013
2013 Considerations regarding appropriate sample size for conducting ferret transmission experiments 2013
2013 N-linked glycosylation of the hemagglutinin protein influences virulence and antigenicity of the 1918 pandemic and seasonal H1N1 influenza A viruses 2013
2013 Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice 2013
2013 Human infections with influenza A(H3N2) variant virus in the United States, 2011-2012 2013
2013 Comparison of the levels of infectious virus in respirable aerosols exhaled by ferrets infected with influenza viruses exhibiting diverse transmissibility phenotypes 2013
2013 Inducible nitric oxide contributes to viral pathogenesis following highly pathogenic influenza virus infection in mice 2013
2013 Alexander (Sasha) I. Klimov, PhD, ScD (1943-2013) 2013
2013 Immunological assessment of influenza vaccines and immune correlates of protection 2013
2013 Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis 2013
2013 Broadly Protective Adenovirus-Based Multivalent Vaccines against Highly Pathogenic Avian Influenza Viruses for Pandemic Preparedness 2013
2013 Simvastatin and oseltamivir combination therapy does not improve the effectiveness of oseltamivir alone following highly pathogenic avian H5N1 influenza virus infection in mice 2013
2013 Kinetics of viral replication and induction of host responses in ferrets differs between ocular and intranasal routes of inoculation 2013
2013 Influenza A(H1N1)pdm09 during air travel 2013
2013 Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice 2013
2013 Transmission studies resume for avian flu 2013
2013 Estimating age-specific cumulative incidence for the 2009 influenza pandemic: A meta-analysis of A(H1N1)pdm09 serological studies from 19 countries 2013
2013 Role of TLR2-dependent IL-10 production in the inhibition of the initial IFN-γ T cell response to porphyromonas gingivalis 2013
2013 Seasonal trivalent inactivated influenza vaccine does not protect against newly emerging variants of influenza a (H3N2v) virus in ferrets 2013
2013 Seropositivity for influenza A(H1N1) pdm09 virus among frontline health care personnel 2013
2013 Tropism and infectivity of influenza virus, including highly pathogenic avian H5N1 virus, in ferret tracheal differentiated primary epithelial cell cultures 2013
2012 Influenza virus titration, antigenic characterization, and serological Mmethods for antibody detection 2012
2012 A Mucosal Subunit Vaccine Protects against Lethal Respiratory Infection with Francisella tularensis LVS 2012
2012 Prevalence of Seropositivity to Pandemic Influenza A/H1N1 Virus in the United States following the 2009 Pandemic 2012
2012 TLR7 Recognition is dispensable for influenza virus a infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in mice 2012
2012 Protecting adults from influenza: Tis the season to learn from the pandemic 2012
2012 Rapid differentiation of monocytes into type I IFN-producing myeloid dendritic cells as an antiviral strategy against influenza virus infection 2012
2012 Seroprevalence of antibodies to Avian influenza A (H5) and A (H9) viruses among market poultry workers, Hanoi, Vietnam, 2001 2012
2012 Low pathogenic avian influenza A (H7N2) virus infection in immunocompromised adult, New York, USA, 2003 2012
2012 Seasonal trivalent inactivated influenza vaccine protects against 1918 Spanish influenza virus infection in ferrets 2012
2012 Avian influenza A (H5N1) virus antibodies in poultry cullers, South Korea, 2003-2004 2012
2012 Innovations in modeling influenza virus infections in the laboratory 2012
2012 Diagnostic performance of the canine Influenza A Virus subtype H3N8 hemagglutination inhibition assay 2012
2012 The first cases of 2009 pandemic influenza A (H1N1) virus infection in the United States: A serologic investigation demonstrating early transmission 2012
2012 Antibodies cross-reactive to influenza a (H3N2) variant virus and impact of 2010-11 seasonal influenza vaccine on cross-reactive antibodies - United States 2012
2012 The 3′ untranslated regions of influenza genomic sequences are 5′PPP-independent ligands for RIG-i 2012
2012 Impact of preexisting adenovirus vector immunity on immunogenicity and protection conferred with an adenovirus-based H5N1 influenza vaccine 2012
2012 Pathogenesis and transmission of swine origin A(H3N2)v influenza viruses in ferrets 2012
2012 Oseltamivir inhibits H7 influenza virus replication in mice inoculated by the ocular route 2012
2012 Local innate immune responses and influenza virus transmission and virulence in ferrets 2012
2012 Pause on avian flu transmission research 2012
2012 Cationic liposome-DNA complexes (CLDC) adjuvant enhances the immunogenicity and cross-protective efficacy of a pre-pandemic influenza A H5N1 vaccine in mice 2012
2012 Reproducibility of serology assays for pandemic influenza H1N1: Collaborative study to evaluate a candidate WHO International Standard 2012
2012 Human pulmonary microvascular endothelial cells support productive replication of highly pathogenic avian influenza viruses: Possible involvement in the pathogenesis of human H5N1 virus infection 2012
2012 Influenza virus respiratory infection and transmission following ocular inoculation in ferrets. 2012
2012 Use of a human influenza challenge model to assess person-to-person transmission: Proof-of-concept study 2012
2011 Transmission of 2009 pandemic influenza a (H1N1) virus among healthcare personnel-Southern California, 2009 2011
2011 A pre-pandemic outbreak of triple-reassortant swine influenza virus infection among university students, South Dakota, 2008 2011
2011 Ocular tropism of influenza a viruses: Identification of H7 subtype-specific host responses in human respiratory and ocular cells 2011
2011 Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus 2011
2011 Contribution of a Streptococcus mutans antigen expressed by a Salmonella vector vaccine in dendritic cell activation 2011
2011 Serologically confirmed household transmission of 2009 pandemic influenza a (H1N1) virus during the first pandemic wave - New York City, april-may 2009 2011
2011 The ferret as a model organism to study influenza A virus infection 2011
2011 TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-κB 2011
2011 Development and evaluation of an M2-293FT cell-based flow cytometric assay for quantification of antibody response to native form of matrix protein 2 of influenza A viruses 2011
2011 Influenza a virus nucleoprotein exploits Hsp40 to inhibit PKR activation 2011
2011 Sensitivity and specificity of serologic assays for detection of human infection with 2009 pandemic H1N1 virus in U.S. populations 2011
2011 Serologic assays for influenza surveillance, diagnosis and vaccine evaluation 2011
2011 Influenza virus aerosol exposure and analytical system for ferrets 2011
2011 TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B 2011
2011 Multiple genes contribute to the virulent phenotype observed in ferrets of an H5N1 influenza virus isolated from Thailand in 2004 2011
2011 Effect of receptor binding domain mutations on receptor binding and transmissibility of avian influenza H5N1 viruses 2011
2011 Efficacy of seasonal live attenuated influenza vaccine against virus replication and transmission of a pandemic 2009 H1N1 virus in ferrets 2011
2011 Pathogenesis and transmission of triple-reassortant swine H1N1 influenza viruses isolated before the 2009 H1N1 pandemic 2011
2011 Infection with highly pathogenic H7 influenza viruses results in an attenuated proinflammatory cytokine and chemokine response early after infection 2011
2011 The 2009 pandemic H1N1 and triple-reassortant swine H1N1 influenza viruses replicate efficiently but elicit an attenuated inflammatory response in polarized human bronchial epithelial cells 2011
2011 The development of vaccine viruses against pandemic A(H1N1) influenza 2011
2010 A synthetic adjuvant to enhance and expand immune responses to influenza vaccines 2010
2010 Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus 2010
2010 Transforming growth factor-β: Activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis 2010
2010 Significant impact of sequence variations in the nucleoprotein on CD8 T cell-mediated cross-protection against influenza A virus infections 2010
2010 Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957 2010
2010 Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection 2010
2010 Role of Toll-like receptors in host responses to a virulence antigen of Streptococcus mutans expressed by a recombinant, attenuated Salmonella vector vaccine 2010
2010 Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication 2010
2010 5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication 2010
2010 Pathogenesis of pandemic influenza A (H1N1) and triple-reassortant swine influenza A (H1) viruses in mice 2010
2010 Influenza A virus transmission: Contributing factors and clinical implications 2010
2010 Serological surveys for 2009 pandemic influenza A H1N1 2010
2009 A live attenuated H1N1 M1 mutant provides broad cross-protection against influenza A viruses, including highly pathogenic A/Vetnam/1203/2004, in Mice 2009
2009 Systems-based candidate genes for human response to influenza infection 2009
2009 Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus 2009
2009 Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein 2009
2009 Development of a new candidate H5N1 avian influenza virus for pre-pandemic vaccine production 2009
2009 Reassortment between avian H5N1 and human H3N2 influenza viruses in ferrets: A public health risk assessment 2009
2009 Requirement of TLR4 and CD14 in dendritic cell activation by Hemagglutinin B from Porphyromonas gingivalis 2009
2009 Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice 2009
2009 Genetic analysis of avian influenza A viruses isolated from domestic waterfowl in live-bird markets of Hanoi, Vietnam, preceding fatal H5N1 human infections in 2004 2009
2009 Ocular infection of mice with influenza A (H7) viruses: A site of primary replication and spread to the respiratory tract 2009
2009 Risk factors associated with subclinical human infection with avian influenza a (H5N1) virus-cambodia, 2006 2009
2009 Early control of H5N1 influenza virus replication by the type I interferon response in mice 2009
2009 Intranasal vaccination with 1918 influenza virus-like particles protects mice and ferrets from lethal 1918 and H5N1 influenza virus challenge 2009
2009 Past, present, and possible future human infection with influenza virus A subtype H7 2009
2009 Fast rise of broadly cross-reactive antibodies after boosting long-lived human memory B cells primed by an MF59 adjuvanted prepandemic vaccine 2009
2009 Generation, characterization and epitope mapping of two neutralizing and protective human recombinant antibodies against influenza A H5N1 viruses 2009
2009 Reply to Zhang 2009
2009 Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: Antiviral potential of exogenous alpha interferon to reduce virus shedding 2009
2009 The public health impact of avian influenza viruses 2009
2009 Human HA and polymerase subunit PB2 proteins confer transmission of an avian influenza virus through the air 2009
2009 Glycogen synthase kinase-3β (GSK3β) inhibition suppresses the inflammatory response to Francisella infection and protects against tularemia in mice 2009
2009 Reproducibility of serologic assays for influenza virus A (H5N1) 2009
2008 TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis 2008
2008 Antigenically distinct MF59-adjuvanted vaccine to boost immunity to H5N1 2008
2008 Pathogenesis of emerging avian influenza viruses in mammals and the host innate immune response 2008
2008 H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice 2008
2008 Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility 2008
2008 Infectivity studies of influenza virus hemagglutinin receptor binding site mutants in mice 2008
2008 A broadly protective vaccine against globally dispersed clade 1 and clade 2 H5N1 influenza viruses 2008
2008 Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus 2008
2008 Influenza A virus (H3N8) in dogs with respiratory disease, Florida 2008
2007 Lack of evidence of avian-to-human transmission of avian influenza A (H5N1) virus among poultry workers, Kano, Nigeria, 2006 2007
2007 New pre-pandemic influenza vaccines: An egg- and adjuvant-independent human adenoviral vector strategy induces long-lasting protective immune responses in mice 2007
2007 DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza h5N1 virus infection 2007
2007 Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type I interferon response in polarized human bronchial epithelial cells 2007
2007 Pathogenesis of avian influenza (H7) virus infection in mice and ferrets: Enhanced virulence of eurasian H7N7 viruses isolated from humans 2007
2007 The Mx1 gene protects mice against the pandemic 1918 and highly lethal human H5N1 influenza viruses 2007
2007 Polygenic virulence factors involved in pathogenesis of 1997 Hong Kong H5N1 influenza viruses in mice 2007
2007 Role of CD80 and CD86 in host immune responses to the recombinant hemagglutinin domain of Porphyromonas gingivalis gingipain and in the adjuvanticity of cholera toxin B and monophosphoryl lipid A 2007
2007 Needle-free skin patch delivery of a vaccine for a potentially pandemic influenza virus provides protection against lethal challenge in mice 2007
2007 Comparison of neutralising antibody assays for detection of antibody to influenza A/H3N2 viruses: An international collaborative study 2007
2007 Growth characterise ties of single gene reassortants of A/Leningrad/134/57(H2N2) influenza virus and cold-adapted mutant A/Leningrad/134/17/ 57(H2N2) 2007
2007 NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I 2007
2007 Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice 2007
2007 A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission 2007
2007 No evidence of avian influenza A (H5N1) among returning US travelers 2007
2007 Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells. 2007
2006 Risk factors for human infection with avian influenza A H5N1, Vietnam, 2004 2006
2006 Three Indonesian clusters of H5N1 virus infection in 2005 2006
2006 Characterization of an influenza A H5N2 reassortant as a candidate for live-attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential 2006
2006 Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses 2006
2006 Interferon and other proinflamatory cytokine responses in vitro following infection with wild-type and cold-adapted reassortant influenza viruses 2006
2006 Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations 2006
2006 Lack of transmission of H5N1 avian-human reassortant influenza viruses in a ferret model 2006
2006 Immunogenicity of Salmonella vector vaccines expressing SBR of Streptococcus mutans under the control of a T7-nirB (dual) promoter system 2006
2006 Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS 2006
2006 Response [2] 2006
2006 Response [4] 2006
2006 Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice 2006
2006 Protection of mice and poultry from lethal H5N1 avian influenza virus through adenovirus-based immunization 2006
2005 A distal regulatory region is required for constitutive and IFN-β-induced expression of murine TLR9 gene 2005
2005 Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: Functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice 2005
2005 Epidemiology: Transmission of equine influenza virus to dogs 2005
2005 Characterization of the reconstructed 1918 Spanish influenza pandemic virus 2005
2005 Evolution of H5N1 avian influenza viruses in Asia 2005
2005 Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis 2005
2005 Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals 2005
2005 Role of mitogen-activated protein kinases and NF-κB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin B 2005
2005 Cross-reactivity to highly pathogenic avian influenza H5N1 viruses after vaccination with nonadjuvanted and MF59-adjuvanted influenza A/Duck/Singapore/97 (H5N3) vaccine: A potential priming strategy 2005
2005 Isolation and characterization of avian influenza viruses, including highly pathogenic H5N1, from poultry in live bird markets in Hanoi, Vietnam, in 2001 2005
2005 Characterization of highly pathogenic H5N1 avian influenza a viruses isolated from South Korea 2005
2005 Seroprevalence of anti-H5 antibody among Thai health care workers after exposure to avian influenza (H5N1) in a tertiary care center. 2005
2004 Preparing for the next influenza pandemic 2004
2004 Confronting the avian influenza threat: Vaccine development for a potential pandemic 2004
2004 Innate immunity in aging: Impact on macrophage function 2004
2004 Immunity to influenza: The challenges of protecting an aging population 2004
2004 Antigenic characteristics of recent avian influenza A H5N1 viruses isolated from humans 2004
2004 Impaired antigen-induced CD8 + T cell clonal expansion in aging is due to defects in antigen presenting cell function 2004
2004 Influenza pandemic vaccines: The imminent challenges from a technical and regulatory perspective 2004
2004 Reassortment between avian apathogenic and human attenuated cold-adapted viruses as an approach for preparing influenza pandemic vaccines 2004
2004 Role of B7 Costimulatory Molecules in Immune Responses and T-Helper Cell Differentiation in Response to Recombinant HagB from Porphyromonas gingivalis 2004
2004 Human illness from avian influenza H7N3, British Columbia 2004
2003 Effectiveness of the quillaja saponin semi-synthetic analog GPI-0100 in potentiating mucosal and systemic responses to recombinant HagB from Porphyromonas gingivalis 2003
2003 Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide 2003
2003 Generation and evaluation of a high-growth reassortant H9N2 influenza A virus as a pandemic vaccine candidate 2003
2003 Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A 2003
2003 Impact of glycosylation on the immunogenicity of a DNA-based influenza H5 HA vaccine 2003
2003 Bacterial invasion by a paracellular route: Divide and conquer 2003
2003 Current methods for assessing T cell responses to influenza. 2003
2003 Evaluation of a genetically modified reassortant H5N1 influenza a virus vaccine candidate generated by plasmid-based reverse genetics 2003
2003 Feasibility of an HA2 domain-based periodontitis vaccine 2003
2003 Systemic and cellular immunity. 2003
2002 Enhanced immunogenicity of a genetic chimeric protein consisting of two virulence antigens of Streptococcus mutans and protection against infection 2002
2002 Cutting edge: Impaired toll-like receptor expression and function in aging 2002
2002 Microbial/host interactions: Mechanisms involved in host responses to microbial antigens 2002
2002 Mechanisms of monophosphoryl lipid A augmentation of host responses to recombinant HagB from Porphyromonas gingivalis 2002
2002 Hydrolysis of epithelial junctional proteins by Porphyromonas gingivalis gingipains 2002
2002 Pathogenesis of avian influenza A (H5N1) viruses in ferrets 2002
2002 Mutant Escherichia coli heat-labile enterotoxin [LT(R192G)] enhances protective humoral and cellular immune responses to orally administered inactivated influenza vaccine 2002
2002 DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice 2002
2002 Lack of evidence for human-to-human transmission of avian influenza A (H9N2) viruses in Hong Kong, China, 1999 2002
2002 Risk of influenza A (H5N1) infection among poultry workers, Hong Kong, 1997-1998 2002
2001 Differential induction of endotoxin tolerance by lipopolysaccharides derived from Porphyromonas gingivalis and Escherichia coli 2001
2001 Molecular correlates of influenza A H5N1 virus pathogenesis in mice 2001
2001 Mucosal vaccination protects mice against influenza A heterosubtypic challenge 2001
2001 Heterosubtypic immunity against human influenza A viruses, including recently emerged avian H5 and H9 viruses, induced by FLU-ISCOM vaccine in mice requires both cytotoxic T-lymphocyte and macrophage function 2001
2001 Mucosal delivery of inactivated influenza vaccine induces B-cell-dependent heterosubtypic cross-protection against lethal influenza a H5N1 virus infection 2001
2001 Immunity to influenza A H9N2 viruses induced by infection and vaccination 2001
2001 Safety and immunogenicity of a recombinant hemagglutinin vaccine for H5 influenza in humans 2001
2001 A vaccine against dental caries: An overview 2001
2001 Vaccines against avian influenza A H9N2 viruses 2001
2000 Production of Interleukin-2 in vitro and in vivo in elderly subjects vaccinated with live and inactivated influenza vaccines and their combination 2000
2000 Proliferative activity of lymphocytes of elderly subjects in vitro after separate and combined immunization with live and inactivated influenza vaccines 2000
2000 Molecular correlates of influenza A H5N1 virus pathogenesis in mice 2000
2000 Immunogenicity and efficacy of Russian live attenuated and US inactivated influenza vaccines used alone and in combination in nursing home residents 2000
2000 Depletion of lymphocytes and diminished cytokine production in mice infected with a highly virulent influenza A (H5N1) virus isolated from humans 2000
2000 A nonionic block co-polymer adjuvant (CRL1005) enhances the immunogenicity and protective efficacy of inactivated influenza vaccine in young and aged mice 2000
2000 Cytokine profiles in parotid saliva from HIV-1-infected individuals: Changes associated with opportunistic infections in the oral cavity 2000
2000 Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexes 2000
2000 Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong 2000
2000 Avian influenza viruses infecting humans 2000
2000 Pathogenesis of and immunity to avian influenza A H5 viruses 2000
1999 Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts 1999
1999 Case-control study of risk factors for avian influenza A (H5N1) disease, Hong Kong, 1997 1999
1999 Host responses to recombinant hemagglutinin B of Porphyromonas gingivalis in an experimental rat model 1999
1999 A mouse model for the evaluation of pathogenesis and immunity to influenza A (H5N1) viruses isolated from humans 1999
1999 Modified M2 proteins produce heterotypic immunity against influenza A virus 1999
1999 Detection of antibody to avian influenza a (H5N1) virus in human serum by using a combination of serologic assays 1999
1998 Formation of humoral and secretory immunity in elderly subjects immunized with influenza vaccines after different protocols 1998
1998 Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines 1998
1998 Characterization of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness 1998
1998 Effect of immune T cells derived from mucosal or systemic tissue on host responses to Porphyromonas gingivalis 1998
1997 Adjuvant activity of the heat-labile enterotoxin from enterotoxigenic Escherichia coli for oral administration of inactivated influenza virus vaccine 1997
1997 Passive Immunization against Dental Plaque Formation in Humans: Effect of a Mouth Rinse Containing Egg Yolk Antibodies (IgY) Specific to Streptococcus mutans 1997
1996 Effect of host responses on the pathogenicity of strains of Porphyromonas gingivalis 1996
1996 Host responses induced by co-infection with Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in a murine model 1996
1995 Induction of salivary IgA responses to Streptococcus mutans antigen I/II after intranasal immunization 1995
1995 Oral immunization studies with streptococcus mutans and influenza vaccines in rhesus macaque monkeys 1995
1995 Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein 1995
1994 Analysis of the primary T-cell response to Sendai virus infection in C57BL/6 mice: CD4+ T-cell recognition is directed predominantly to the hemagglutinin-neuraminidase glycoprotein 1994
1994 Codominant mixtures of viruses in reference strains of influenza virus due to host cell variation 1994
1993 Influence of host cell-mediated variation on the international surveillance of influenza a (h3n2) viruses 1993
1993 Protective salivary immunoglobulin A responses against Streptococcus mutans infection after intranasal immunization with S. mutans antigen I/II coupled to the B subunit of cholera toxin 1993
1992 Liposomes and conjugate vaccines for antigen delivery and induction of mucosal immune responses 1992
1992 Amino acid sequence identity between the HA1 of influenza A (H3N2) viruses grown in mammalian and primary chick kidney cells 1992
1992 Application of directigen FLU-A for the detection of influenza A virus in human and nonhuman specimens 1992
1992 Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells 1992
1992 Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts 1992
1992 Extent of γδ T cell involvement in the pneumonia caused by sendai virus 1992
1992 Humoral response to Porphyromonas (Bacteroides) gingivalis in rats: Time course and T-cell dependence 1992
1991 A method for generating antigen-specific rat T helper cell clones 1991
1991 Effect of immune bovine milk on Streptococcus mutans in human dental plaque 1991
1990 Characterization of rat T helper cell clones specific for Bacteroides gingivalis antigen 1990
1990 Direct sequencing of the HA gene of influenza (H3N2) virus in original clinical samples reveals sequence identity with mammalian cell-grown virus 1990
1989 Efficacy of Inactivated Influenza a Virus (H3N2) Vaccines Grown in Mammalian Cells or Embryonated Eggs 1989
1989 Extensive heterogeneity in the hemagglutinin of egg-grown influenza viruses from different patients 1989
1989 Liposomes as oral adjuvants. 1989
1988 Antigenic and structural characterization of multiple subpopulations of H3N2 influenza virus from an individual 1988
1987 Protection of gnotobiotic rats against dental caries by passive immunization with bovine milk antibodies to Streptocococcus mutans 1987
1987 Characterization of subtype-specific and cross-reactive helper-T-cell clones recognizing influenza virus hemagglutinin 1987
1987 Host cell-mediated variation in H3N2 influenza viruses 1987
1987 Novel oral vaccines: the effectiveness of cloned gene products on inducing secretory immune responses. 1987
1987 Oral vaccines and the secretory immune system 1987
1985 Cleavage of bovine skin type III collagen by proteolytic enzymes. Relative resistance of the fibrillar form 1985
1985 Murine helper T lymphocyte response to influenza virus: recognition of haemagglutinin by subtype-specific and cross-reactive T cell clones 1985
1985 Recognition of influenza virus hemagglutinin by subtype-specific and cross-reactive proliferative T cells: contribution of HA1 and HA2 polypeptide chains 1985
1981 In vitro antibody response to influenza virus. II. Specificity of helper T cells recognizing hemagglutinin 1981

Book

Year Title Altmetric
2009 Chapter 2 Use of Animal Models to Understand the Pandemic Potential of Highly Pathogenic Avian Influenza Viruses.  Ed. 73.  2009
2007 WHO biosafety risk assessment and guidelines for the production and quality control of human influenza pandemic vaccines 2007
2004 Influenza vaccines generated by reverse genetics.  Ed. 283.  2004

Chapter

Year Title Altmetric
2012 Inactivated influenza vaccines.  257-293. 2012

Education And Training

  • Doctor of Philosophy in Immunopathology Residency Program, University of Alabama at Birmingham 1992
  • Doctor of Dental Science in Dentistry, National Autonomous University of Mexico 1980
  • Full Name

  • Jannet Katz