Selected Publications

Academic Article

Year Title Altmetric
2022 X-ray perception: Animal studies of sensory and behavioral responses to X-raysFrontiers in Cellular Neuroscience.  16. 2022
2022 Somatotopic Mapping of the Fingers in the Somatosensory Cortex Using Functional Magnetic Resonance Imaging: A Review of LiteratureFrontiers in Neuroanatomy.  16. 2022
2021 X-ray excited luminescence spectroscopy and imaging with NaGdF4:Eu and Tb 2021
2021 Feasibility of cerium-doped LSO particles as a scintillator for x-ray induced optogeneticsJournal of Neural Engineering.  18. 2021
2021 Focused Ultrasound Ablation of an Arteriovenous Malformation ModelFrontiers in Neurology.  12. 2021
2021 Somatotopic Arrangement of the Human Primary Somatosensory Cortex Derived From Functional Magnetic Resonance ImagingFrontiers in Neuroscience.  14. 2021
2020 Catheter placement selection for convection-enhanced delivery of therapeutic agents to brain tumorsF1000Research.  9:1415. 2020
2020 White matter and neurite morphology differ in psychogenic nonepileptic seizuresAnnals of Clinical and Translational Neurology.  7:1973-1984. 2020
2020 Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal controlJournal of Controlled Release.  324:172-180. 2020
2020 Somatotopic Arrangement of Eight Distinct Skin Areas in the Human Primary Somatosensory Cortex Derived from Functional Magnetic Resonance Imaging 2020
2020 A benchtop approach to the location specific blood brain barrier opening using focused ultrasound in a rat modelJournal of Visualized Experiments.  2020:1-13. 2020
2020 Effects of a carbohydrate‐restricted diet on hepatic lipid content in adolescents with non‐alcoholic fatty liver disease: A pilot, randomized trial 2020
2020 Correlating the passive response of eye and brain to head impact using MEMS IMUs on 3D-printed human head phantomPhysiological Measurement.  41. 2020
2019 LITE-1 Dependent X-Ray Sensitivity in C. elegans 2019
2019 Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control 2019
2019 Role of Surface Chemistry in Mediating the Uptake of Ultrasmall Iron Oxide Nanoparticles by Cancer CellsACS Applied Materials and Interfaces.  11:17157-17166. 2019
2019 Organic Fluorophore Coated Polycrystalline Ceramic LSO:Ce Scintillators for X-ray Bioimaging 2019
2018 Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback controlScientific Reports.  8. 2018
2018 Rationale and design of a single-blind, randomised controlled trial of exercise training for managing learning and memory impairment in persons with multiple sclerosisBMJ Open.  8. 2018
2018 Ultrasound-Triggered Delivery of Anticancer Therapeutics from MRI-Visible Multilayer MicrocapsulesAdvanced Therapeutics.  1. 2018
2018 In vitro studies of heparin-coated magnetic nanoparticles for use in the treatment of neointimal hyperplasiaNanomedicine: Nanotechnology, Biology and Medicine.  14:1191-1200. 2018
2018 Effectiveness of a carbohydrate restricted diet to treat non-alcoholic fatty liver disease in adolescents with obesity: Trial design and methodologyContemporary Clinical Trials.  68:95-101. 2018
2018 Sensing Passive Eye Response to Impact Induced Head Acceleration Using MEMS IMUsIEEE Transactions on Biomedical Circuits and Systems.  12:182-191. 2018
2017 Portable perfusion phantom for quantitative DCE-MRI of the abdomenMedical Physics.  44:5198-5209. 2017
2017 T 1-Enhanced MRI-visible nanoclusters for imaging-guided drug deliveryNanoscale.  9:11785-11792. 2017
2017 Retinal changes in the Tg-SwDI mouse model of Alzheimer's diseaseNeuroscience.  354:43-53. 2017
2017 Ketamine modulates hippocampal neurochemistry and functional connectivity: A combined magnetic resonance spectroscopy and resting-state fMRI study in healthy volunteersMolecular Psychiatry.  22:562-569. 2017
2016 Shape-dependent cellular behaviors and relaxivity of iron oxide-based: T 1 MRI contrast agentsNanoscale.  8:17506-17515. 2016
2016 Association between expiratory central airway collapse and respiratory outcomes among smokersJournal of the American Medical Association.  315:498-505. 2016
2015 Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomasJournal of Neuro-Oncology.  122:585-593. 2015
2015 Mapping the macaque superior temporal sulcus: Functional delineation of vergence and version eye-movement-related activity 2015
2015 Fast Prototyping of Near-Field Antennas for Magnetic Resonance Imaging by Using MoM Simulations and 3-D Printing TechnologyIEEE Antennas and Propagation Magazine.  57:261-266. 2015
2015 Ultrathin iron oxide nanowhiskers as positive contrast agents for magnetic resonance imagingAdvanced Functional Materials.  25:490-494. 2015
2014 Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophreniaNeuropsychopharmacology.  39:1020-1030. 2014
2014 Basal ganglia volume in unmedicated patients with schizophrenia is associated with treatment response to antipsychotic medicationPsychiatry Research.  221:6-12. 2014
2014 Vergence eye movements in patients with schizophreniaVision Research.  102:64-70. 2014
2013 Examination of value of the future and health beliefs to explain dietary and physical activity behaviorsResearch in Social and Administrative Pharmacy.  9:851-862. 2013
2013 Magnetic transfer contrast accurately localizes substantia nigra confirmed by histologyBiological Psychiatry.  73:289-294. 2013
2012 Ocular convergence deficits in schizophreniaFrontiers in Psychiatry.  3. 2012
2012 Antipsychotic drugs alter functional connectivity between the medial frontal cortex, hippocampus, and nucleus accumbens as measured by H215O PETFrontiers in Psychiatry.  3. 2012
2012 Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imagingSchizophrenia Research.  140:136-142. 2012
2012 Potentiation of concentric force and acceleration only occurs early during the stretch-shortening cycleJournal of Strength and Conditioning Research.  26:2345-2355. 2012
2011 Aberrant visual circuitry associated with normal spatial match-to-sample accuracy in schizophreniaPsychiatry Research.  193:138-143. 2011
2011 Smaller regional gray matter volume in homeless african american cocaine-dependent men: a preliminary reportOpen Neuroimaging Journal.  5:57-64. 2011
2010 Spin-echo SS-PARSE: A PARSE MRI method to estimate frequency, R2 and R2 in a single shotMagnetic Resonance Imaging.  28:1270-1282. 2010
2010 Age and gender differences in hip extension and flexion torque steadiness 2010
2010 Assessments of function and biochemistry of the anterior cingulate cortex in schizophreniaBiological Psychiatry.  68:625-633. 2010
2010 Temporal characteristics of cold pain perceptionNeuroscience Letters.  480:12-15. 2010
2010 Cortical regions for the processing of stereoscopic motion in depth as revealed by fMRI in the alert rhesus monkeyJournal of Vision.  9:684-684. 2010
2007 Validation of V-SS-PARSE for single-shot flow measurementMagnetic Resonance Imaging.  25:335-340. 2007
2006 Developing functional magnetic resonance imaging techniques for alert macaque monkeysImmunoMethods.  38:210-220. 2006


Year Title Altmetric
2016 AC.Ketamine Modulates Hippocampal Neurochemistry and Functional Connectivity 2016
2016 Executive functions: Eye movements and human neurological disorders.  117-122. 2016
2014 Volumetric Analyses Of Tracheomalacia Independently Predicts Airflow Obstruction.  A3553-A3553. 2014

Research Overview

  • My primary areas of research are basic neuroscience and MRI physics. I have a great interest in creating tools to facilitate neuroscience research, especially novel neuroimaging methods. In particular, I am interested in developing new contrast mechanisms and refining quantitative functional imaging techniques. I also have an interest in developing techniques for non-invasive neuromodulation and non-invasive MRI guided targeted drug delivery to the brain.
  • Principal Investigator On

    Investigator On

  • Brain Thermometry: A Non-Invasive Method for Detecting Neuroinflammation in RA  awarded by RHEUMATOLOGY RESEARCH FOUNDATION
  • Changes in Visual Cortical Connectivity Following Central Visual Field Loss  awarded by National Eye Institute/NIH/DHHS
  • Characterization of Multiple Factors in Training and Plasticity in Central Vision Loss  awarded by National Eye Institute/NIH/DHHS
  • Circadian and Sleep Mechanisms among Racial Groups for Nicotine Dependence, Craving, and Withdrawal  awarded by National Institute on Drug Abuse/NIH/DHHS
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Core Support Grant - Preclinical Imaging Shared Facility  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Support Grant  awarded by National Cancer Institute/NIH/DHHS
  • Comprehensive Cancer Center Support Grant - Animal Imaging Shared Resource  awarded by National Cancer Institute/NIH/DHHS
  • Contribution of Glutamate Excess and Inflammation to Progressive White Matter Changes in Psychosis  awarded by National Institute of Mental Health/NIH/DHHS
  • Depletion of Pancreatic Lipid Improves Beta-Cell Function in Early Type 2 Diabetes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Diet and Adolescent Brain  awarded by National Institute of Child Health and Human Development/NIH/DHHS
  • Enhanced Assessment of Organ Lipid and Liver Disease for the Civitan International Neuroimaging Laboratory  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION
  • Glutamate, Brain Connectivity and Duration of Untreated Psychosis  awarded by National Institute of Mental Health/NIH/DHHS
  • Immersive Virtual Walking as Treatment for Neuropathic Pain in Spinal Cord Injury: Examing Treatment Efficacy and Cortical Mechanisms  awarded by DOD - Department of Defense
  • Investigating the Impact of Cognition on Capacity in Multiple Sclerosis  awarded by National Institute of Child Health and Human Development/NIH/DHHS
  • Major Upgrade for UAB Bruker BioSpec Preclinical 9.4T MRI  awarded by NIH - OFFICE OF THE DIRECTOR
  • McKnight Brain Aging Registry  awarded by University of Miami
  • Measuring Neuroinflammation in Chronic Fatigue Syndrome with Whole-brain Magnetic Resonance Spectroscopy  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Moderately CHO-Restricted Diet as Treatment Targeting Improvement in Hepatic Lipid and Insulin Sensitivity in Adolescents with NAFLD  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Neuroimaging Biomarkers for Seizures  awarded by OCEAN STATE RESEARCH INSTITUTE INC
  • Noninvasive Biomarkers to Advance Emerging DBS Electrode Technologies in Parkinson’s Disease  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Passive Eye Response as a Surrogate for Brain Response to Head Acceleration  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Private Grant  awarded by BOSTON SCIENTIFIC CORPORATION
  • Private Grant  awarded by EMD SERONO
  • Prognostic Indicators for Reading and Pediatric Vision Impairment  awarded by Administration for Community Living/DHHS
  • RII Track-2 FEC: The Creation of Next Generation Tools for Neuroscience - Noninvasive Radioluminescence Approaches to Optogenetics  awarded by Clemson University
  • SULT4a1, A Novel Neuroprotective Protein in Stroke  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Skeletal Muscle in Rheumatoid Arthritis  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
  • The Efficacy Of A Visualizing Reading Intervention On Improving The Brain's Reading Network In Children With Autism  awarded by National Institute on Deafness & Other Communication Disorders/NIH/DHHS
  • The Efficacy of a Visualizing Reading Intervention on Improving the Brain’s Reading Network in Children with Autism  awarded by UNIVERSITY OF ALABAMA (TUSCALOOSA)
  • Trajectories of Treatment Response as Window into the Heterogeneity of Psychosis: a Longitudinal Multimodal Imaging Study in Medication-naieve first Episode Psychosis Patients  awarded by National Institute of Mental Health/NIH/DHHS
  • Treadmill Walking Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: A Systematically-Developed Randomized Controlled Trial  awarded by National Institute of Child Health and Human Development/NIH/DHHS
  • UAB Alzheimer's Disease Research Center  awarded by National Institute on Aging/NIH/DHHS
  • UAB Alzheimer's Disease Research Center - Clinical Core  awarded by NIH - National Institutes of Health/DHHS
  • Understanding Hippocampal Internal Architecture in Human Temporal Lobe Epilepsy -- From MRI to Epigenetics  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS
  • Unlocking Dystonia from Parkinson's Disease with Directional DBS Technology  awarded by Fox (Michael J.) Foundation for Parkinson's Research
  • Visual Brain Core-Research Resources on Visual Dysfunction and Plasticity  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION
  • [18F] FPEB Studies of the mGluR5 Receptor and Methamphetamine Abuse  awarded by National Institute on Drug Abuse/NIH/DHHS
  • Education And Training

  • Doctor of Philosophy in Vision Science / Physiological Optics, University of Alabama at Birmingham 2012
  • Bachelor of Science or Mathematics in Biochemistry, Biophysics and Molecular Biology, Clemson University 1997
  • Full Name

  • Mark Bolding