Mark Bolding Ph.D.

Mark Bolding Ph.D.
Associate Professor

Scientist (C), O'Neal Comprehensive Cancer Center , School of Medicine
Associate Professor (P), Radiology , School of Medicine
Scientist, Experimental Therapeutics , O'Neal Comprehensive Cancer Center
Scientist (C), Center for Clinical and Translational Science (CCTS) , General Clinical Research Center
Scientist (C), Comprehensive Neuroscience Center , General Clinical Research Center
Scientist (C), Alzheimer's Disease Center , Neurology
Scientist (C), Evelyn F. McKnight Brain Institute , Neurology
Assistant Professor (S), Vision Sciences (Retired Org) , School of Optometry
Associate Scientist (C), Vision Science Research Center (Retired Org) , Vision Sciences (Retired Org)
Assistant Professor (S), Neurobiology , Academic Joint Departments
Associate Professor (S), Biomedical Engineering , School of Engineering

Selected Publications

Academic Article

Year	Title	Altmetric
2022	X-ray perception: Animal studies of sensory and behavioral responses to X-rays. Frontiers in Cellular Neuroscience. 16. 2022
2022	Somatotopic Mapping of the Fingers in the Somatosensory Cortex Using Functional Magnetic Resonance Imaging: A Review of Literature. Frontiers in Neuroanatomy. 16. 2022
2021	X-ray excited luminescence spectroscopy and imaging with NaGdF4:Eu and Tb 2021
2021	Feasibility of cerium-doped LSO particles as a scintillator for x-ray induced optogenetics. Journal of Neural Engineering. 18. 2021
2021	Focused Ultrasound Ablation of an Arteriovenous Malformation Model. Frontiers in Neurology. 12. 2021
2021	Somatotopic Arrangement of the Human Primary Somatosensory Cortex Derived From Functional Magnetic Resonance Imaging. Frontiers in Neuroscience. 14. 2021
2020	Catheter placement selection for convection-enhanced delivery of therapeutic agents to brain tumors. F1000Research. 9:1415. 2020
2020	White matter and neurite morphology differ in psychogenic nonepileptic seizures. Annals of Clinical and Translational Neurology. 7:1973-1984. 2020
2020	Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control. Journal of Controlled Release. 324:172-180. 2020
2020	Somatotopic Arrangement of Eight Distinct Skin Areas in the Human Primary Somatosensory Cortex Derived from Functional Magnetic Resonance Imaging 2020
2020	A benchtop approach to the location specific blood brain barrier opening using focused ultrasound in a rat model. Journal of Visualized Experiments. 2020:1-13. 2020
2020	Effects of a carbohydrate‐restricted diet on hepatic lipid content in adolescents with non‐alcoholic fatty liver disease: A pilot, randomized trial 2020
2020	Correlating the passive response of eye and brain to head impact using MEMS IMUs on 3D-printed human head phantom. Physiological Measurement. 41. 2020
2019	LITE-1 Dependent X-Ray Sensitivity in C. elegans 2019
2019	Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control 2019
2019	Role of Surface Chemistry in Mediating the Uptake of Ultrasmall Iron Oxide Nanoparticles by Cancer Cells. ACS Applied Materials and Interfaces. 11:17157-17166. 2019
2019	Organic Fluorophore Coated Polycrystalline Ceramic LSO:Ce Scintillators for X-ray Bioimaging 2019
2018	Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control. Scientific Reports. 8. 2018
2018	Rationale and design of a single-blind, randomised controlled trial of exercise training for managing learning and memory impairment in persons with multiple sclerosis. BMJ Open. 8. 2018
2018	Ultrasound-Triggered Delivery of Anticancer Therapeutics from MRI-Visible Multilayer Microcapsules. Advanced Therapeutics. 1. 2018
2018	In vitro studies of heparin-coated magnetic nanoparticles for use in the treatment of neointimal hyperplasia. Nanomedicine: Nanotechnology, Biology and Medicine. 14:1191-1200. 2018
2018	Effectiveness of a carbohydrate restricted diet to treat non-alcoholic fatty liver disease in adolescents with obesity: Trial design and methodology. Contemporary Clinical Trials. 68:95-101. 2018
2018	Sensing Passive Eye Response to Impact Induced Head Acceleration Using MEMS IMUs. IEEE Transactions on Biomedical Circuits and Systems. 12:182-191. 2018
2017	Portable perfusion phantom for quantitative DCE-MRI of the abdomen. Medical Physics. 44:5198-5209. 2017
2017	T 1-Enhanced MRI-visible nanoclusters for imaging-guided drug delivery. Nanoscale. 9:11785-11792. 2017
2017	Retinal changes in the Tg-SwDI mouse model of Alzheimer's disease. Neuroscience. 354:43-53. 2017
2017	Ketamine modulates hippocampal neurochemistry and functional connectivity: A combined magnetic resonance spectroscopy and resting-state fMRI study in healthy volunteers. Molecular Psychiatry. 22:562-569. 2017
2016	Shape-dependent cellular behaviors and relaxivity of iron oxide-based: T 1 MRI contrast agents. Nanoscale. 8:17506-17515. 2016
2016	Association between expiratory central airway collapse and respiratory outcomes among smokers. Journal of the American Medical Association. 315:498-505. 2016
2015	Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomas. Journal of Neuro-Oncology. 122:585-593. 2015
2015	Mapping the macaque superior temporal sulcus: Functional delineation of vergence and version eye-movement-related activity 2015
2015	Fast Prototyping of Near-Field Antennas for Magnetic Resonance Imaging by Using MoM Simulations and 3-D Printing Technology. IEEE Antennas and Propagation Magazine. 57:261-266. 2015
2015	Ultrathin iron oxide nanowhiskers as positive contrast agents for magnetic resonance imaging. Advanced Functional Materials. 25:490-494. 2015
2014	Ventral tegmental area/midbrain functional connectivity and response to antipsychotic medication in schizophrenia. Neuropsychopharmacology. 39:1020-1030. 2014
2014	Basal ganglia volume in unmedicated patients with schizophrenia is associated with treatment response to antipsychotic medication. Psychiatry Research. 221:6-12. 2014
2014	Vergence eye movements in patients with schizophrenia. Vision Research. 102:64-70. 2014
2013	Examination of value of the future and health beliefs to explain dietary and physical activity behaviors. Research in Social and Administrative Pharmacy. 9:851-862. 2013
2013	Magnetic transfer contrast accurately localizes substantia nigra confirmed by histology. Biological Psychiatry. 73:289-294. 2013
2012	Ocular convergence deficits in schizophrenia. Frontiers in Psychiatry. 3. 2012
2012	Antipsychotic drugs alter functional connectivity between the medial frontal cortex, hippocampus, and nucleus accumbens as measured by H215O PET. Frontiers in Psychiatry. 3. 2012
2012	Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging. Schizophrenia Research. 140:136-142. 2012
2012	Potentiation of concentric force and acceleration only occurs early during the stretch-shortening cycle. Journal of Strength and Conditioning Research. 26:2345-2355. 2012
2011	Aberrant visual circuitry associated with normal spatial match-to-sample accuracy in schizophrenia. Psychiatry Research. 193:138-143. 2011
2011	Smaller regional gray matter volume in homeless african american cocaine-dependent men: a preliminary report. Open Neuroimaging Journal. 5:57-64. 2011
2010	Spin-echo SS-PARSE: A PARSE MRI method to estimate frequency, R2 and R2^′ in a single shot. Magnetic Resonance Imaging. 28:1270-1282. 2010
2010	Age and gender differences in hip extension and flexion torque steadiness 2010
2010	Assessments of function and biochemistry of the anterior cingulate cortex in schizophrenia. Biological Psychiatry. 68:625-633. 2010
2010	Temporal characteristics of cold pain perception. Neuroscience Letters. 480:12-15. 2010
2010	Cortical regions for the processing of stereoscopic motion in depth as revealed by fMRI in the alert rhesus monkey. Journal of Vision. 9:684-684. 2010
2007	Validation of V-SS-PARSE for single-shot flow measurement. Magnetic Resonance Imaging. 25:335-340. 2007
2006	Developing functional magnetic resonance imaging techniques for alert macaque monkeys. ImmunoMethods. 38:210-220. 2006

Chapter

Year	Title	Altmetric
2016	AC.Ketamine Modulates Hippocampal Neurochemistry and Functional Connectivity 2016
2016	Executive functions: Eye movements and human neurological disorders. 117-122. 2016
2014	Volumetric Analyses Of Tracheomalacia Independently Predicts Airflow Obstruction. A3553-A3553. 2014

Research Overview

My primary areas of research are basic neuroscience and MRI physics. I have a great interest in creating tools to facilitate neuroscience research, especially novel neuroimaging methods. In particular, I am interested in developing new contrast mechanisms and refining quantitative functional imaging techniques. I also have an interest in developing techniques for non-invasive neuromodulation and non-invasive MRI guided targeted drug delivery to the brain.