Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 A pilot study of combined endurance and resistance exercise rehabilitation for verbal memory and functional connectivity improvement in epilepsy 2019
2019 It's more than low BMI: Prevalence of cachexia and associated mortality in COPD 2019
2019 The importance of resistance exercise training to combat neuromuscular aging 2019
2019 A guide for using NIH Image J for single slice cross-sectional area and composition analysis of the thigh from computed tomography 2019
2019 Chronic Inflammation in Rheumatoid Arthritis and Mediators of Skeletal Muscle Pathology and Physical Impairment: A Review 2019
2018 Medical Rehabilitation: Guidelines to Advance the Field With High-Impact Clinical Trials 2018
2018 Rationale and design of a single-blind, randomised controlled trial of exercise training for managing learning and memory impairment in persons with multiple sclerosis 2018
2018 A high-protein diet or combination exercise training to improve metabolic health in individuals with long-standing spinal cord injury: a pilot randomized study 2018
2018 Muscle Fn14 gene expression is associated with fat-free mass retention during energy deficit at high altitude 2018
2018 Paralytic and nonparalytic muscle adaptations to exercise training versus high-protein diet in individuals with long-standing spinal cord injury 2018
2018 Immunohistochemical Identification of Human Skeletal Muscle Macrophages. 2018
2018 Composition and richness of the serum microbiome differ by age and link to systemic inflammation 2018
2018 Human neuromuscular aging: Sex differences revealed at the myocellular level 2018
2018 Molecular regulation of exercise-induced muscle fiber hypertrophy 2018
2018 Effects of aging and Parkinson's disease on motor unit remodeling: Influence of resistance exercise training 2018
2018 Getting the Brain Into Shape: Exercise in Neurological Disorders 2018
2018 Quantification and characterization of grouped type I myofibers in human aging 2018
2018 Weight management and physical activity throughout the cancer care continuum 2018
2017 High-intensity exercise acutely increases substantia nigra and prefrontal brain activity in parkinson’s disease 2017
2017 Potential Causes of Elevated REE after High-Intensity Exercise 2017
2017 Randomized, four-arm, dose-response clinical trial to optimize resistance exercise training for older adults with age-related muscle atrophy 2017
2017 Motion sensors in multiple sclerosis: Narrative review and update of applications 2017
2017 Metformin to Augment Strength Training Effective Response in Seniors (MASTERS): Study protocol for a randomized controlled trial 2017
2016 OPN-a induces muscle inflammation by increasing recruitment and activation of pro-inflammatory macrophages 2016
2016 Exercise Promotes Healthy Aging of Skeletal Muscle 2016
2016 Heightened TWEAK-NF-κB signaling and inflammation-associated fibrosis in paralyzed muscles of men with chronic spinal cord injury 2016
2016 Speed and Incline-Based Vs Resistance-Based Treadmill Walking Tests for Determining Cardiorespiratory Fitness: 2451 June 3, 10: 45 AM - 11: 00 AM. 2016
2016 Ribosome biogenesis may augment resistance training-induced myofiber hypertrophy and is required for myotube growth in vitro 2016
2016 Exercise Medicine for Osteoarthritis: Research Strategies to Maximize Effectiveness 2016
2015 Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism 2015
2015 Transforming growth factor beta (TGF-β) is a muscle biomarker of disease progression in ALS and correlates with smad expression 2015
2015 Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals 2015
2015 Muscle fiber type, achilles tendon length, potentiation, and running economy 2015
2015 Muscle inflammation susceptibility: A prognostic index of recovery potential after hip arthroplasty? 2015
2015 Serum from human burn victims impairs myogenesis and protein synthesis in primary myoblasts 2015
2015 The Clinical Translation Gap in Child Health Exercise Research: A Call for Disruptive Innovation 2015
2015 The effects of age and resistance loading on skeletal muscle ribosome biogenesis 2015
2015 Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits 2015
2014 Mechanosensitivity may be enhanced in skeletal muscles of spinal cord-injured versus able-bodied men 2014
2014 Aging and energetics' 'Top 40' future research opportunities 2010-2013 2014
2014 Mechanosensitivity may be enhanced in skeletal muscles of spinal cord-injured versus able-bodied men 2014
2014 Novel, high-intensity exercise prescription improves muscle mass, mitochondrial function, and physical capacity in individuals with Parkinson's disease 2014
2014 Exercise biology and medicine: Innovative research to improve global health 2014
2013 Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans 2013
2013 Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape 2013
2013 Increased expression of atrogenes and TWEAK family members after severe burn injury in nonburned human skeletal muscle 2013
2013 Skeletal muscle signaling associated with impaired glucose tolerance in spinal cord-injured men and the effects of contractile activity 2013
2013 Cluster analysis reveals differential transcript profiles associated with resistance training-induced human skeletal muscle hypertrophy 2013
2013 Importance of three-dimensional geometric analysis in the assessment of the athlete's heart 2013
2012 Meeting synopsis: Advances in skeletal muscle biology in health and disease (Gainesville, Florida, February 22nd to 24th 2012) - day 1: "Cell signaling mechanisms mediating muscle atrophy and hypertrophy" and "muscle force, calcium handling, and stress response" 2012
2012 Meeting synopsis: Advances in skeletal muscle biology in health and disease (Gainesville, Florida, February 22nd to 24th 2012) - day 2: "muscle diseases and regeneration" and "clinical/translational research" 2012
2012 Feasibility of exercising adults with asthma: a randomized pilot study 2012
2012 Inflammatory and protein metabolism signaling responses in human skeletal muscle after burn injury 2012
2012 Characterization and regulation of mechanical loading-induced compensatory muscle hypertrophy. 2012
2012 Simvastatin impairs ADP-stimulated respiration and increases mitochondrial oxidative stress in primary human skeletal myotubes 2012
2011 Novel insights into interactions between mitochondria and xanthine oxidase in acute cardiac volume overload 2011
2011 Exercise economy in African American and European American women 2011
2011 Tendon length and joint flexibility are related to running economy 2011
2011 Exercise dosing to retain resistance training adaptations in young and older adults 2011
2011 Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy 2011
2011 Age, muscle fatigue, and walking endurance in pre-menopausal women 2011
2010 Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice 2010
2010 Does your (genetic) alphabet soup spell "runner"? 2010
2010 Differential genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loading 2010
2009 Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans 2009
2009 Does habitual dietary intake influence myofiber hypertrophy in response to resistance training? A cluster analysis 2009
2008 Regulation of muscle size in humans: Role of myostatin? 2008
2008 Increased strength and decreased flexibility are related to reduced oxygen cost of walking 2008
2008 Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: A cluster analysis 2008
2008 Modulation of the dystrophin-associated protein complex in response to resistance training in young and older men 2008
2008 The exercise dose response: Key lessons from the past 2008
2007 Load-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: A cluster analysis 2007
2007 Reply to Dr. Heinemeier [14] 2007
2007 Erratum: SIRT1 is significantly elevated in mouse and human prostate cancer (Cancer Research (2007) 67, (6612-6618)) 2007
2007 Take two NSAIDs and call on your satellite cells in the morning 2007
2007 SIRT1 is significantly elevated in mouse and human prostate cancer 2007
2007 Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humans 2007
2007 Contributions of force and velocity to improved power with progressive resistance training in young and older adults 2007
2006 Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women 2006
2006 Exercise program implementation proves not feasible during acute care hospitalization 2006
2006 Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adults 2006
2006 Ethnic differences in triceps surae muscle-tendon complex and walking economy 2006
2005 Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and women 2005
2005 Inverse relationship between exercise economy and oxidative capacity in muscle 2005
2005 Impact of resistance loading on myostatin expression and cell cycle regulation in young and older men and women 2005
2005 Exercise over-stress and maximal muscle oxidative metabolism: A 31P magnitec resonance spectroscopy case report 2005
2005 Age differences in knee extension power, contractile velocity, and fatigability 2005
2004 Myogenic protein expression before and after resistance loading in 26- and 64-yr-old men and women 2004
2004 Effects of resistance training on older adults 2004
2003 Hormonal responses from concentric and eccentric muscle contractions 2003
2003 Gender differences in resistance-training-induced myofiber hypertrophy among older adults 2003
2002 Age is independently related to muscle metabolic capacity in premenopausal women 2002
2002 Resistance training and intra-abdominal adipose tissue in older men and women 2002
2001 Relation between in vivo and in vitro measurements of skeletal muscle oxidative metabolism 2001
2001 The interrelationship among muscle mass, strength, and the ability to perform physical tasks of daily living in younger and older women 2001
2001 Muscle metabolic economy is inversely related to exercise intensity and type II myofiber distribution 2001
2001 Mechanical load increases muscle IGF-I and androgen receptor mRNA concentrations in humans 2001
2001 High-resistance versus variable-resistance training in older adults 2001
2000 Resistance training increases total energy expenditure and free-living physical activity in older adults 2000
2000 Validation of Fitness/Physical Abilities Tests for Evaluating the Ability to Do Job-Related Tasks 2000
2000 In situ localization of cholesterol in skeletal muscle by use of a monoclonal antibody 2000
2000 Evaluation of the strength-size relationship in vivo using various muscle size indices 2000
2000 Obesity-Prone Children Can Benefit from High-Intensity Exercise 2000
2000 Resistance Exercise Countermeasures for Space Flight: Implications of Training Specificity 2000
1999 Enhanced protein electrophoresis technique for separating human skeletal muscle myosin heavy chain isoforms 1999
1998 Bed rest decreases mechanically induced myofiber wounding and consequent wound-mediated FGF release 1998
1998 A role for high intensity exercise on energy balance and weight control 1998
1998 Impact of resistance exercise during bed rest on skeletal muscle sarcopenia and myosin isoform distribution 1998
1997 Myofiber wound-mediated FGF release and muscle atrophy during bedrest 1997
1997 Resistance exercise prevents sarcopenia during bed rest unloading 1997
1997 Resistance exercise prevents plantar flexor deconditioning during bed rest 1997
1997 Resistance exercise training and the orthostatic response 1997
1997 Time course changes in contractile strength resulting from isokinetic exercise and β2agonist administration 1997
1997 Evaluation of surface electromyography during maximal voluntary contraction 1997
1997 Resistance exercise maintains skeletal muscle protein synthesis during bed rest 1997
1995 The effects of albuterol and isokinetic exercise on the quadriceps muscle group 1995
1993 Changes in body composition, diet, and strength of bodybuilders during the 12 weeks prior to competition. 1993
1993 Frequency and volume of resistance training: Effect on cervical extension strength 1993
1991 Acid-base balance in the body 1991
1991 Exercise physiology corner: Blood buffering 1991

Research Overview

  • MAJOR RESEARCH INTERESTS
    Mechanisms of human skeletal muscle regeneration and muscle mass regulation are the major emphases in our laboratory. Muscle atrophy and reduced functional capacity are well-established, deleterious consequences of acute (e.g., surgery, trauma, disuse, burn) and chronic (e.g., Parkinson’s disease, arthritis, cancer, heart failure, spinal cord injury) conditions—the most widespread and insidious of which is the degenerative process of normal aging. Our research priorities span three, inter-related focus areas: (i) to determine the cellular and molecular mechanisms driving muscle regeneration following damage, surgery, or injury, while identifying differences responsible for regeneration impairment in certain phenotypes; (ii) to determine key processes responsible for myofiber hypertrophy, and to exploit these processes with countermeasures to promote muscle re-growth in conditions that induce muscle atrophy; and (iii) to better understand the primary etiology of muscle atrophy in acute and chronic conditions. We have a keen interest in the role of proinflammatory cytokine signaling on skeletal muscle atrophy, regrowth, and regeneration, and recently identified a state of muscle inflammation susceptibility (MuIS) in humans involving TWEAK and TNF-α/NFĸB signaling that is noted in vivo and inhibits satellite (stem) cell behavior in vitro. We suspect MuIS is a key determinant of individual responsiveness to treatments promoting muscle re-growth including exercise training.
  • Principal Investigator On

  • The Exercise and Physical Activity Collaborative Team (ExPact): A Proposed MoTrPAC Clinical Center  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2016 - 2022
  • Interdisciplinary Training in Pathobiology and Rehabilitation Medicine  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2017 - 2022
  • National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Admin Oversight Component  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Coordinating Center  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • Rehabilitation Research Resource to Enhance Clinical Trials (REACT)  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • Overcoming TWEAK Signaling to Restore Muscle and Mobility after Joint Replacement  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • Research Acceleration to Maximize Warrior Performance (RAMP)  awarded by Office of Naval Research 2018 - 2019
  • The Role of Inflammation on Muscle Growth in Aging Atrophied Adults  awarded by National Institute on Aging/NIH/DHHS 2017 - 2019
  • Precision High Intensity Training through Epigenetics (PHITE)  awarded by Wright State University 2016 - 2019
  • Novel Actions of Metformin to Augment Resistance Training Adaptations in Older Adults  awarded by UNIVERSITY OF KENTUCKY (RESEARCH FOUNDATION) 2014 - 2019
  • Interdisciplinary Training in Pathobiology and Rehabilitation Medicine  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2012 - 2017
  • Using in vitro Approaches to Improve Muscle Regrowth in Atrophied Older Humans  awarded by National Institute on Aging/NIH/DHHS 2012 - 2015
  • Establishing a State-of-the-Art Core Facility to Advance Interdisciplinary Exercise Medicine Research  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2013
  • Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults  awarded by National Institute on Aging/NIH/DHHS 2007 - 2013
  • Regulation of Human Muscle Protein Metabolism Following Burn Injury  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2011 - 2013
  • Mechanisms of Skeletal Muscle Satellite Cell Regulation in Aging  awarded by National Institute on Aging/NIH/DHHS 2007 - 2010
  • Investigator On

  • Treadmill Walking Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: A Systematically-Developed Randomized Controlled Trial  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2018 - 2023
  • ACES - ACE Inhibitors Combined with Exercise for Hypertensive Seniors  awarded by National Institute on Aging/NIH/DHHS 2017 - 2022
  • Targeting Skeletal Muscle to Improve Metabolic Health in Individuals with Spinal Cord Injury  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2017 - 2022
  • Smad Signaling in Skeletal Muscle as a Biomarker of Disease Progression in ALS  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2016 - 2021
  • National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Collaborative Opportunities  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Promo/Dissemination Component  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • National Resource Center for High-Impact Clinical Trials in Medical Rehabilitation: Tech Developments Component  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • Rehabilitation Research Resource to Enhance Clinical Trials (REACT)  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2020
  • Resveratrol and Exercise to Treat Functional Limitations in Late Life  awarded by National Institute on Aging/NIH/DHHS 2018 - 2020
  • UAB Center for Clinical and Translational Science (CCTS) (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS 2015 - 2019
  • Skeletal Muscle in Rheumatoid Arthritis  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2016 - 2019
  • Symptoms and Skeletal Muscle in Persons with Heart Failure with Preserved Ejection Fraction  awarded by National Institute of Nursing Research/NIH/DHHS 2017 - 2019
  • Race - Adiposity Interactions Regulate Mechanisms Determining Insulin Sensitivity  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2013 - 2019
  • UAB Obesity Training Program  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2014 - 2017
  • Exercise Intensity, Metabolic Rate & Insulin Sensitivity  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2016
  • Teaching Activities

  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Fall Term 2017) 2017
  • GBS750 - NERVES MUSCLES AND BONES (Spring Term 2017) 2017
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Fall Term 2016) 2016 - 2017
  • GBS750 - NERVES MUSCLES AND BONES (Spring Term 2016) 2016
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Fall Term 2015) 2015
  • GBS750 - Nerves Muscles & Bone (Spring Term 2015) 2015
  • GBSC700 - Journal Clubs (Spring Term 2015) 2015
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Spring Term 2015) 2015
  • GBS746J - Exercise Med JC (Fall Term 2014) 2014
  • GBS746J - Exercise Med JC (Summer Term 2014) 2014
  • GBS746J - Exercise Med JC (Spring Term 2014) 2014
  • GBS750 - Nerves Muscles & Bone (Spring Term 2014) 2014
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Spring Term 2014) 2014
  • GBS750 - NERVES MUSCLES AND BONES (Spring Term 2014) 2014
  • GBS746J - Exercise Med JC (Fall Term 2013) 2013
  • GBS746 - Special Topics (Spring Term 2013) 2013
  • GBS750 - Nerves Muscles & Bone (Spring Term 2013) 2013
  • GBS750 - NERVES MUSCLES AND BONES (Spring Term 2013) 2013
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Fall Term 2012) 2012 - 2013
  • GBS746 - Special Topics Biomed Sci I (Fall Term 2012) 2012
  • GBS750 - Nerves Muscles & Bone (Spring Term 2012) 2012
  • PHY780 - Center Exercise Medicine JC (Spring Term 2012) 2012
  • PHY780 - Center Exercise Medicine JC (Fall Term 2011) 2011
  • GBS750 - Nerves Muscles & Bone (Spring Term 2011) 2011
  • PCL1180R - MUSCULOSKELETAL & SKIN REMEDIAL (Spring Term 2011) 2011
  • PCL1180 - MUSCULOSKELETAL & SKIN (Fall Term 2010) 2010
  • PCL1180 - MUSCULOSKELETAL/SKIN (Fall Term 2009) 2009
  • PCL1180 - MUSCULOSKELETAL / SKIN (Spring Term 2008) 2008
  • 01-230R - REMEDIAL PHYSIOLOGY (Fall Term 2007) 2007
  • 01-230 - MEDICAL PHYSIOLOGY (Spring Term 2007) 2007
  • 01-230 - MEDICAL PHYSIOLOGY (Spring Term 2007) 2007
  • Full Name

  • Marcas Bamman