Selected Publications

Academic Article

Year Title Altmetric
2020 The clinical course of actinic keratosis correlates with underlying molecular mechanisms 2020
2019 Combined mTORC1/mTORC2 inhibition blocks growth and induces catastrophic macropinocytosis in cancer cells 2019
2019 Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1 +/−/ODC transgenic mice 2019
2019 Vimentin intermediate filament assembly regulates fibroblast invasion in fibrogenic lung injury 2019
2019 Global gene expression of histologically normal primary skin cells from BCNS subjects reveals "single-hit" effects that are influenced by rapamycin 2019
2019 CD5 on dendritic cells regulates CD4+ and CD8+ T cell activation and induction of immune responses 2019
2018 Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema 2018
2018 SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas 2018
2018 Cutaneous exposure to lewisite causes acute kidney injury by invoking dna damage and autophagic response 2018
2018 214 High fat diet accelerates UVB-induced development of basal cell and squamous cell carcinoma in Ptch+/-/SKH-1 mice 2018
2017 Basal cell carcinoma pathogenesis and therapy involving hedgehog signaling and beyond 2017
2017 Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1+/−/SKH-1 Hairless Mice 2017
2017 The impact of oral Polypodium leucotomos extract on ultraviolet B response: A human clinical study 2017
2017 IL-23 Inhibits Melanoma Development by Augmenting DNA repair and modulating T cell subpopulations 2017
2017 Low-dose cadmium exposure induces peribronchiolar fibrosis through site-specific phosphorylation of vimentin 2017
2016 ATF4 regulates arsenic trioxide-mediated NADPH oxidase, ER-mitochondrial crosstalk and apoptosis 2016
2016 Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype 2016
2016 AKT1 activation is obligatory for spontaneous BCC tumor growth in a murine model that mimics some features of basal cell nevus syndrome 2016
2016 Activating transcription factor 4 underlies the pathogenesis of arsenic trioxide-mediated impairment of macrophage innate immune functions 2016
2016 Molecular Mechanism Underlying Pathogenesis of Lewisite-Induced Cutaneous Blistering and Inflammation: Chemical Chaperones as Potential Novel Antidotes 2016
2016 Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals 2016
2016 A murine model for the development of melanocytic nevi and their progression to melanoma 2016
2016 Limited ATF4 expression in degenerating retinas with ongoing ER stress promotes photoreceptor survival in a mouse model of autosomal dominant retinitis pigmentosa 2016
2016 Retinoid X receptor agonists upregulate genes responsible for the biosynthesis of all-trans-retinoic acid in human epidermis 2016
2016 Ionizing Radiation Exposure and Basal Cell Carcinoma Pathogenesis 2016
2016 Arsenic attenuates gli signaling, increasing or decreasing its transcriptional program in a context-dependent manner 2016
2016 Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma 2016
2015 Biochemical evaluation of antioxidant activity in extracts and polysaccharide fractions of seaweeds 2015
2015 Aberrant GLI1 activation in DNA damage response, carcinogenesis and chemoresistance 2015
2015 Fisetin inhibits UVB-induced cutaneous inflammation and activation of PI3K/AKT/NFκB signaling pathways in SKH-1 hairless mice 2015
2015 Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells 2015
2015 Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations 2015
2015 In vivo suppression of heat shock protein (HSP)27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemical 2015
2015 Introduction 2015
2015 Shh and p50/Bcl3 signaling crosstalk drives pathogenesis of BCCs in Gorlin syndrome 2015
2014 Gli1 protein regulates the S-phase checkpoint in tumor cells via bid protein, and its inhibition sensitizes to DNA Topoisomerase 1 inhibitors 2014
2014 Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch 2014
2014 Sonic hedgehog signaling in basal cell nevus syndrome 2014
2014 Inhibition of p38 MAPK signaling augments skin tumorigenesis via NOX2 driven ROS generation 2014
2014 Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway 2014
2014 Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways 2014
2014 Soluble E-cadherin: A critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling 2014
2014 Cyclooxygenases: Mediators of UV-induced skin cancer and potential targets for prevention 2014
2014 Cytokines and chemokines: Disease models, mechanisms, and therapies 2014
2014 GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis 2014
2014 Hair follicle disruption facilitates pathogenesis to UVB-induced cutaneous inflammation and basal cell carcinoma development in ptch+/- mice 2014
2014 Role of CRD-BP in the growth of human basal cell carcinoma cells 2014
2014 The mechanistic basis of arsenicosis: Pathogenesis of skin cancer 2014
2013 Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by Targeting Akt-ERK axis 2013
2013 Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption 2013
2013 Delphinidin Reduces Cell Proliferation and Induces Apoptosis of Non-Small-Cell Lung Cancer Cells by Targeting EGFR/VEGFR2 Signaling Pathways 2013
2013 Arsenic-induced cutaneous hyperplastic lesions are associated with the dysregulation of Yap, a Hippo signaling-related protein 2013
2013 Chlorine induces the unfolded protein response in murine lungs and skin 2013
2013 Geraniol inhibits murine skin tumorigenesis by modulating COX-2 expression, Ras-ERK1/2 signaling pathway and apoptosis 2013
2013 Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: Role of mitochondrial membrane potential disruption and consequent caspases activation 2013
2013 Grape seeds: Ripe for cancer chemoprevention 2013
2013 Milestones in photocarcinogenesis. 2013
2013 Rapamycin targeting mTOR and hedgehog signaling pathways blocks human rhabdomyosarcoma growth in xenograft murine model 2013
2013 Nitric oxide-releasing sulindac is a novel skin cancer chemopreventive agent for UVB-induced photocarcinogenesis 2013
2013 Vorinostat, an HDAC inhibitor attenuates epidermoid squamous cell carcinoma growth by dampening mTOR signaling pathway in a human xenograft murine model 2013
2012 Introduction to the special issue honoring professor David R. Bickers 2012
2012 Metformin, an antidiabetic agent reduces growth of cutaneous squamous cell carcinoma by targeting mTOR signaling pathway 2012
2012 Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis 2012
2012 Combined inhibition of p38 and Akt signaling pathways abrogates cyclosporine A-mediated pathogenesis of aggressive skin SCCs 2012
2012 D-Limonene modulates inflammation, oxidative stress and Ras-ERK pathway to inhibit murine skin tumorigenesis 2012
2012 Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling 2012
2012 IL-17 mediated inflammation promotes tumor growth and progression in the skin 2012
2011 Unfolded protein response signaling and MAP kinase pathways underlie pathogenesis of arsenic-induced cutaneous inflammation 2011
2011 Cyclosporine a mediates pathogenesis of aggressive cutaneous squamous cell carcinoma by augmenting epithelial-mesenchymal transition: Role of TGFβ signaling pathway 2011
2011 Liver Kinase B1 (LKB1) in the pathogenesis of epithelial cancers 2011
2011 Rapamycin and mTORC1 inhibition in the mouse: Skin cancer prevention 2011
2011 Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin 2011
2011 Procarcinogenic effects of cyclosporine A are mediated through the activation of TAK1/TAB1 signaling pathway 2011
2011 Role of epidermal primary cilia in the homeostasis of skin and hair follicles 2011
2011 Liver kinase B1 (LKB1) in the pathogenesis of UVB-induced murine basal cell carcinoma 2011
2011 Pathogenesis of nonmelanoma skin cancers in organ transplant recipients 2011
2011 New Agents for Prevention of Ultraviolet-Induced Nonmelanoma Skin Cancer 2011
2011 Pharmacological Activation of p53 in Cancer Cells 2011
2011 Prospects for skin cancer treatment and prevention: The potential contribution of an engineered virus 2011
2011 Resveratrol targets transforming growth factor-Β2 signaling to block UV-induced tumor progression 2011
2011 TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine 2011
2010 Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response 2010
2010 Targeting wild-type and mutant p53 with small molecule CP-31398 blocks the growth of rhabdomyosarcoma by inducing reactive oxygen species-dependent apoptosis 2010
2010 The other end of the rainbow: Infrared and skin 2010
2010 Eugenol precludes cutaneous chemical carcinogenesis in mouse by preventing oxidative stress and inflammation and by inducing apoptosis 2010
2010 Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice 2010
2010 Targeting ornithine decarboxylase for the prevention of nonmelanoma skin cancer in humans 2010
2009 Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: Involvement of inflammation, Ras-ERK pathway and apoptosis 2009
2009 Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms 2009
2009 Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis 2009
2009 Nutraceuticals as natural healers: Emerging evidences 2009
2009 When apoptosis meets autophagy: deciding cell fate after trauma and sepsis 2009
2009 Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathway 2009
2009 Guilandina bonduc L. possesses antioxidant activity and precludes ferric nitrilotriacetate (Fe-NTA) induced renal toxicity and tumor promotion response 2009
2008 Two new bioactive oleanane triterpene glycosides from Terminalia arjuna. 2008
2008 Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis 2008
2008 Two new bioactive oleanane triterpene glycosides from Terminalia arjuna 2008
2008 Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol 2008
2008 A critical role for the proapoptotic protein bid in ultraviolet-induced immune suppression and cutaneous apoptosis 2008
2008 Topically applied vitamin E prevents massive cutaneous inflammatory and oxidative stress responses induced by double application of 12-O-tetradecanoylphorbol-13-acetate (TPA) in mice 2008
2008 Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice 2008
2008 Quercus infectoria galls possess antioxidant activity and abrogates oxidative stress-induced functional alterations in murine macrophages 2008
2008 Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinoma 2008
2007 CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice 2007
2007 Resveratrol: A review of preclinical studies for human cancer prevention 2007
2007 Sixtieth birthday of Dr. Hasan Mukhtar, a man with vision: Thirty-five years of dedicated efforts in developing preventive toxicology and chemoprevention of cancer 2007
2007 Protective effect of Rumex patientia (English Spinach) roots on ferric nitrilotriacetate (Fe-NTA) induced hepatic oxidative stress and tumor promotion response 2007
2007 Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD 2007
2007 Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: Implications for cancer prevention 2007
2007 Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease 2007
2007 Eruca sativa seeds possess antioxidant activity and exert a protective effect on mercuric chloride induced renal toxicity 2007
2007 Effect of pre-treatment of almond oil on ultraviolet B-induced cutaneous photoaging in mice 2007
2007 Protective effect of Didymocarpus pedicellata on ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and hyperproliferative response 2007
2006 Augmentation and proliferation of T lymphocytes and Th-1 cytokines by Withania somnifera in stressed mice 2006
2006 Hedgehog signalling in skin development and cancer 2006
2006 Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice 2006
2006 Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice 2006
2006 Resveratrol inhibits proliferation of human epidermoid carcinoma A431 cells by modulating MEK1 and AP-1 signalling pathways 2006
2006 Molecular target-based therapy of pancreatic cancer 2006
2006 Oxidative stress in the pathogenesis of skin disease 2006
2005 Differential expression of E prostanoid receptors in murine and human non-melanoma skin cancer 2005
2005 Inhibitory effect of 18β3-glycyrrhetinic acid on 12-O-tetradecanoyl phorbol-13-acetate-induced cutaneous oxidative stress and tumor promotion in mice 2005
2005 Two new compounds from the galls of Quercus infectoria with nitric oxide and superoxide inhibiting ability 2005
2005 Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells 2005
2005 Vitamin E inhibits hepatic oxidative stress, toxicity and hyperproliferation in rats treated with the renal carcinogen ferric nitrilotriacetate 2005
2005 Elevated polyamines lead to selective induction of apoptosis and inhibition of tumorigenesis by (-)-epigallocatechin-3-gallate (EGCG) in ODC/Ras transgenic mice 2005
2005 Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice 2005
2004 Inhibition of smoothened signaling prevents ultraviolet B-induced basal cell carcinomas through regulation of fas expression and apoptosis 2004
2004 Low iron diet retards 12-O-tetradecanoyl phorbol-13-acetate-mediated tumor promotion in murine skin 2004
2004 Nimbidin suppresses functions of macrophages and neutrophils: Relevance to its antiinflammatory mechanisms 2004
2004 Immunoprevention of Basal Cell Carcinomas with Recombinant Hedgehog-interacting Protein 2004
2004 Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice 2004
2004 Free radical generating agents lead to the rapid progression of benign skin tumors to carcinoma in iron-overloaded mice 2004
2004 Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice 2004
2004 Tocotrienol-rich fraction of palm oil activates p53, modulates Bax/Bcl2 ratio and induces apoptosis independent of cell cycle association. 2004
2004 Antiinflammatory evaluation of alcoholic extract of galls of Quercus infectoria 2004
2004 Roles of Catalase and Hydrogen Peroxide in Green Tea Polyphenol-Induced Chemopreventive Effects 2004
2003 Cyclooxygenases in the skin: Pharmacological and toxicological implications 2003
2003 Glyceryl trinitrate, a nitric oxide donor, abrogates ferric nitrilotriacetate-induced oxidative stress and renal damage 2003
2003 Baculoviral p35 inhibits oxidant-induced activation of mitochondrial apoptotic pathway 2003
2003 Antioxidants prevent UV-induced apoptosis by inhibiting mitochondrial cytochrome c release and caspase activation in Spodoptera frugiperda (Sf9) cells 2003
2003 Palm oil alleviates 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion response in murine skin 2003
2003 Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis 2003
2003 Progressive iron overload enhances chemically mediated tumor promotion in murine skin 2003
2003 Host-pathogen interactions during apoptosis 2003
2002 Protoporphyrin-IX accumulation and cutaneous tumor regression in mice using a ferrochelatase inhibitor 2002
2002 Reduced cyclin D1 ubiquitination in UVB-induced murine squamous cell carcinomas 2002
2002 Induction of p57 is required for cell survival when exposed to green tea polyphenols 2002
2002 Iron augments stage-I and stage-II tumor promotion in murine skin 2002
2002 Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: Implications for therapeutic approaches 2002
2002 Low iron state is associated with reduced tumor promotion in a two-stage mouse skin carcinogenesis model 2002
2002 Oxidative stress and experimental carcinogenesis 2002
2002 Stage-specific alterations of cyclin expression during UVB-induced murine skin tumor development 2002
2002 Stage-specific alterations of cyclin expression during UVB-induced murine skin tumor development. 2002
2002 Ultraviolet-B-induced G1 arrest is mediated by downregulation of cyclin-dependent kinase 4 in transformed keratinocytes lacking functional p53 2002
2001 Chemoprevention of basal cell carcinomas in the ptc1+/- mouse-green and black tea 2001
2001 Chemopreventive effects of green tea polyphenols correlate with reversible induction of p57 expression 2001
2001 Pyrazole aroyl hydrazones as ligands-I 1,3-diphenylpyrazole-4-carboxaldehyde benzoyl hydrazone as ligand for metal complexes 2001
2001 Chemopreventive effects of green tea polyphenols correlate with reversible induction of p57 expression. 2001
2001 Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia 2001
2001 Nitroglycerin: A NO donor inhibits TPA-mediated tumor promotion in murine skin 2001
2001 Anti-tumor promoting activity of Asteracantha longifolia against experimental hepatocarcinogenesis in rats 2001
2001 Induction of oxyradicals by arsenic: Implication for mechanism of genotoxicity 2001
2001 Ultraviolet B (UVB)-induced COX-2 expression in murine skin: An immunohistochemical study 2001
2000 Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53 2000
2000 Induction of hepatic antioxidants in freshwater catfish (Channa punctatus Bloch) is a biomarker of paper mill effluent exposure 2000
2000 In vitro inhibition of carcinogen-induced mutagenicity by Cassia occidentalis and Emblica officinalis 2000
2000 Green tea polyphenols and tannic acid act as potent inhibitors of phorbol ester-induced nitric oxide generation in rat hepatocytes independent of their antioxidant properties 2000
2000 Pyrazole aroyl hydrazones as ligands: Complexes of 1,3-diphenylpyrazole -4-carboxaldehyde 2-chlorobenzoylhydrazone with Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Hg(II), Sn(II), Bi(III) and Pb(II) 2000
2000 Evaluation of the efficacy of Lawsonia alba in the alleviation of carbon tetrachloride-induced oxidative stress 2000
2000 Inhibitory effect of Emblica officinalis on the in vivo clastogenicity of benzo[a]pyrene and cyclophosphamide in mice 2000
2000 Novel approaches to chemoprevention of skin cancer 2000
1999 Evidence that ferric nitrilotriacetate mediates oxidative stress by down-regulating DT-diaphorase activity: Implications for carcinogenesis 1999
1999 Age-dependent renal accumulation of 4-hydroxy-2-nonenal (HNE)-modified proteins following parenteral administration of ferric nitrilotriacetate commensurate with its differential toxicity: Implications for the involvement of HNE-protein adducts in oxidative stress and carcinogenesis 1999
1999 The baculovirus antiapoptotic p35 gene also functions via an oxidant-dependent pathway 1999
1999 Copper-nitrilotriacetate (Cu-NTA) is a potent inducer of proliferative response both in liver and kidney but is a complete renal carcinogen 1999
1999 Potassium bromate (KBrO3) induces renal proliferative response and damage by elaborating oxidative stress 1999
1999 Reconstituted 3-dimensional human skin as a novel in vitro model for studies of carcinogenesis 1999
1999 Ellagic acid ameliorates nickel induced biochemical alterations: Diminution of oxidative stress 1999
1999 Ferrochelatase, a novel target for photodynamic therapy of cancer. 1999
1999 Glutathione redox system in oxidative lung injury 1999
1999 Glyceryl trinitrate, a nitric oxide donor, suppresses renal oxidant damage caused by potassium bromate 1999
1999 Green tea protects against psoralen plus ultraviolet A-induced photochemical damage to skin 1999
1999 In vitro cultured Spodoptera frugiperda insect cells: Model for oxidative stress-induced apoptosis 1999
1999 Nordihydroguairetic acid is a potent inhibitor of ferric-nitrilotriacetate-mediated hepatic and renal toxicity, and renal tumour promotion, in mice 1999
1999 Photoprotective effect of black tea extracts against UVB-induced phototoxicity in skin 1999
1999 Protective effect of Cassia occidentalis extract on chemical-induced chromosomal aberrations in mice 1999
1998 Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complex 1998
1998 Augmentation of 12-O-tetradecanoyl 13-phorbol acetate-mediated tumor promoting response by the porphyrin photosensitization of 7,12-dimethyl benz[a]anthracene-initiated murine skin: Role of in situ generated reactive oxygen species 1998
1998 Responses of circulating fish phagocytes to paper mill effluent exposure 1998
1998 Attenuation of iron-nitrilotriacetate (Fe-NTA)-mediated renal oxidative stress, toxicity and hyperproliferative response by the prophylactic treatment of rats with garlic oil 1998
1998 Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: Implications for the involvement of oxidative stress 1998
1998 Effect of iron overload on the benzoyl peroxide-mediated tumor promotion in mouse skin 1998
1998 Iron overload augments 7,12-dimethylbenz(a)anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin tumorigenesis 1998
1998 α-tocopherol (vitamin-E) ameliorates ferric nitrilotriacetate (Fe-NTA)-dependent renal proliferative response and toxicity: Diminution of oxidative stress 1998
1998 Drought tolerance by lentil rhizobia (Rhizobium leguminosarum) from arid and semiarid areas of Pakistan 1998
1997 Effect of peanut plants incorporated as green manure on the growth and grain yield of succeeding wheat 1997
1997 Evidence that Fe-NTA-induced renal prostaglandin F2α is responsible for hyperplastic response in kidney: Implications for the role of cyclooxygenase-dependent arachidonic acid metabolism in renal tumor promotion 1997
1997 Analgesic activity of bacosine, a new triterpene isolated from Bacopa monnieri 1997
1997 Evidence that iron-overload promotes 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in mice 1997
1997 Mechanism of asbestos-mediated DNA damage: role of heme and heme proteins. 1997
1996 L-2-oxothiazolidine-4-carboxylate, an in situ inducer of glutathione, protects against paraquat-mediated pulmonary damage in rat 1996
1996 Glutathione metabolizing enzymes and oxidative stress in ferric nitrilotriacetate mediated hepatic injury. 1996
1996 Coordination of copperpolyamine complex with imidazoles potentiates its superoxide dismutase mimicking activity and abolishes its interaction with albumin 1996
1996 Paraquat induced DNA damage by reactive oxygen species 1996
1996 Porphyrin-mediated photosensitization has a weak tumor promoting activity in mouse skin: Possible role of in situ-generated reactive oxygen species 1996
1995 Novel copper superoxide dismutase mimics and damage mediated by O2.-. 1995
1995 Ferric nitrilotriacetate (Fe-NTA) is a potent hepatic tumor promoter and acts through the generation of oxidative stress 1995
1995 Evidence that in situ generated reactive oxygen species act as a potent stage i tumor promoter in mouse skin 1995
1995 Augmentation of chrysotile-induced oxidative stress by BHA in mice lungs 1995
1995 Crude extracts of hepatoprotective plants, Solanum nigrum and Cichorium intybus inhibit free radical-mediated DNA damage 1995
1995 Metabolic requirements for induction of contact hypersensitivity to immunotoxic polyaromatic hydrocarbons 1995
1994 Differential Role of Hydrogen Peroxide and Organic Peroxides Augmenting Asbestos-Mediated DNA Damage: Implications for Asbestos Induced Carcinogenesis 1994
1993 Synthesis and reactivity in inorganic and metal-organic chemistry 1993
1993 Asbestos induced oxidative injury to DNA 1993
1993 Free radicals and trace elements 1993
1993 Ras protein p21 processing enzyme farnesyltransferase in chemical carcinogen—induced murine skin tumors 1993
1992 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1992
1992 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1992
1992 Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 1992
1992 Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 1992
1992 Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 1992
1992 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1992
1992 Photodynamic effects of chloroaluminum phthalocyanine tetrasulfonate are mediated by singlet oxygen: In vivo and in vitro studies utilizing hepatic microsomes as a model membrane source 1992
1992 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1992
1991 All-trans retinoic acid protects against conversion of chemically induced and ultraviolet b radiation-induced skin papillomas to carcinomas 1991
1991 Photodynamic therapy of murine skin tumors using Photofrin®-II 1991
1991 Synthesis and reactivity in inorganic and metal-organic chemistry 1991
1991 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1991
1991 Synthesis and reactivity in inorganic and metal-organic chemistry 1991
1991 Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 1991
1991 Synthesis and reactivity in inorganic and Metal-Organic chemistry 1991
1991 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1991
1991 Synthesis and reactivity in inorganic and metal-organic chemistry 1991
1991 Cadmium-mediated Induction of Cellular Defence Mechanism: A Novel Example for the Development of Adaptive Response against a Toxicant 1991
1991 Involvement of singlet oxygen in chloroaluminum phthalocyanine tetrasulfonate-mediated photoenhancement of lipid peroxidation in rat epidermal microsomes 1991
1991 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1991
1990 Evidence for the involvement of singlet oxygen in the photodestruction by chloroaluminum phthalocyanine tetrasulfonate 1990
1990 Nickel-mediated inhibition in the glutathione-dependent protection against lipid peroxidation 1990
1990 Inhibition of benzoyl peroxide-mediated tumor promotion in 7,12-dimethylbenz(a)anthracene-Initiated skin of sencar mice by antioxidants nordihydroguaiaretic acid and diallyl sulfide 1990
1990 Synthesis and Reactivity, in Inorganic and Metal-Organic Chemistry 1990
1989 Effect of Dietary Tannic Acid on Epidermal, Lung, and Forestomach Polycyclic Aromatic Hydrocarbon Metabolism and Tumorigenicity in Sencar Mice 1989
1989 Malignant conversion of UV radiation and chemically induced mouse skin benign tumors by free-radical-generating compounds 1989
1989 Evidence for the metabolism of tumor promoter organic hydroperoxides into free radicals by human carcinoma skin keratinocytes: An ESR-spin trapping study 1989
1989 A novel mechanism for the generation of superoxide anions in hematoporphyrin derivative-mediated cutaneous photosensitization. Activation of the xanthine oxidase pathway 1989
1989 Antimutagenic activity of green tea polyphenols 1989
1989 Evaluation of nickel complexes of bioligands - Effect on distribution profile 1989
1989 Inhibition of the high affinity Fc receptor (Fc(γ)RI) on human monocytes by porphyrin photosensitization is highly specific and mediated by the generation of superoxide radicals 1989
1989 Skin chemical carcinogenesis 1989
1989 Synthesis and Reactivity in Inorganic and Metal-organic Chemistry 1989
1988 Alleviation of nickel-induced biochemical alterations by chelating agents 1988
1988 Alleviation of nickel-induced biochemical alterations by chelating agents 1988
1988 Comparative effects of chelating drugs on trace metal and biochemical alterations in the rat 1988
1988 In situ evidence for the involvement of superoxide anions in cutaneous porphyrin photosensitization 1988
1988 Effect of exposure to toxic gas on the population of Bhopal: Part III--Assessment of toxic manifestations in humans--haematological and biochemical studies. 1988
1988 Influence of partial hepatectomy on the metabolic disposition of nickel in rats 1988
1988 Involvement of superoxide anions in cutaneous porphyrin photosensitization: An in vivo study 1988
1988 Dietary anticarcinogens and cancer prevention. 1988
1988 Differential role of reactive oxygen intermediates in photofrin-I- and photofrin-II-mediated photoenhancement of lipid peroxidation in epidermal microsomal membranes 1988
1988 Inhibition of the skin tumorigenicity of (±)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene by tannic acid, green tea polyphenols and quercetin in Sencar mice 1988
1987 Role of glutathione metabolizing enzymes in nickel mediated induction of hepatic glutathione 1987
1987 Evidence for the involvement of hydroxyl radicals in nickel mediated enhancement of lipid peroxidation: Implications for nickel carcinogenesis 1987
1987 Evaluation of chelating drugs on the toxicity, excretion, and distribution of nickel in poisoned rats 1987
1987 Studies on the schiff base complexes of oxovanadium(Iv) 1987
1987 Cytochrome P-450 dependent metabolism of testosterone in rat skin 1987
1987 Evaluation of chelating drugs on the toxicity, excretion, and distribution of nickel in poisoned rats 1987
1987 Pharmacokinetics and metabolic disposition of nickel in poisoned rats - Effect of chelating drugs 1987
1986 Evaluation of LD50 of some polyaminocarboxylic acids used as chelating drugs in metal intoxication 1986
1986 Removal of nickel by chelating drugs from the organs of nickel poisoned rats 1986
1985 Synthesis and reactivity of some α,α'-bis(2- and 4- substituted benzoyletllurium dichlorides 1985
1981 Selective spectrophotometric determination of uranium(VI) using salicylaldimine antipyrine 1981
1970 Synthesis and reactivity in inorganic and metal-organic chemistry 1970


Year Title Altmetric
2017 UV and skin: Photocarcinogenesis.  67-103. 2017
2015 Cutaneous Toxicology of Arsenic.  301-314. 2015

Investigator On

  • RXR Rexinoids for Cancer Chemoprevention  awarded by National Cancer Institute/NIH/DHHS 2017 - 2022
  • RXR Rexinoids for Cancer Chemoprevention - Program Integration and Management  awarded by National Cancer Institute/NIH/DHHS 2017 - 2022
  • RXR Rexinoids for Cancer Chemoprevention - Project 1: Evaluation if UAB30 on Skin Cancer Biomarkers in Human Renal Transplant Recipients  awarded by National Cancer Institute/NIH/DHHS 2017 - 2022
  • RXR Rexinoids for Cancer Chemoprevention - Project 3: Molecular Targets of Rexinoid Action in Skin  awarded by National Cancer Institute/NIH/DHHS 2017 - 2022
  • Topical Chemoprevention of Skin Cancer Biomarkers  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • RT-SQuARED-M Method to Study the Precise Role of Mitochondria in the Oxidative Damage Caused by Environmental Toxins  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2018 - 2020
  • Dietary Prevention of Photodamage in Skin with Grapes: A Human Clinical Study  awarded by California Table Grape Commission 2014 - 2018
  • RT-SQuARED-M Method to Study the Precise Role of Mitochondria in the Oxidative Damage Caused by Environmental Toxins  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2018
  • UAB Skin Disease Research Center  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2015
  • UAB Skin Disease Research Center - Administrative Core - Core A  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2009 - 2015
  • The Effect of Polypodium Leucotomos on UV-Induced Photodamage in Skin  awarded by HENRY FORD HOSPITAL 2014 - 2015
  • Education And Training

  • Doctor of Philosophy Level Degree in Chemistry, Aligarh Muslim University 1980
  • Master of Sciences or Mathematics in Inorganic Chemistry, University of Lucknow 1977
  • Bachelor of Science or Mathematics in Chemistry, University of Lucknow 1975
  • Full Name

  • Mohammad Athar