Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision.  Journal of Human Lactation.  117:631-645. 2019
2019 Complex regulation of mitochondrial function during cardiac development.  Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  8. 2019
2019 Enhancing the engraftment of human induced pluripotent stem cell-derived cardiomyocytes via a transient inhibition of rho kinase activity.  Journal of Visualized Experiments.  2019. 2019
2019 Proteomics insight into the production of monoclonal antibody.  Microbial Genomics.  145:177-185. 2019
2019 HDAC inhibition induces autophagy and mitochondrial biogenesis to maintain mitochondrial homeostasis during cardiac ischemia/reperfusion injury.  Journal of Molecular and Cellular Cardiology.  130:36-48. 2019
2019 Novel biomanufacturing platform for large-scale and high-quality human T cells production.  Journal of Biological Engineering.  13. 2019
2019 Mitoquinone ameliorates pressure overload-induced cardiac fibrosis and left ventricular dysfunction in mice.  Redox Biology.  21. 2019
2019 Y-27632 preconditioning enhances transplantation of human-induced pluripotent stem cell-derived cardiomyocytes in myocardial infarction mice.  Journal of Nonprofit and Public Sector Marketing.  115:343-356. 2019
2019 Intracellular metabolism analysis of Clostridium cellulovorans via modeling integrating proteomics, metabolomics and fermentation.  Process Biochemistry.  2019
2019 Targeted Exosomes for Drug Delivery: Biomanufacturing, Surface Tagging, and Validation.  Aging Health.  2019
2018 Bioprocess development of antibody-drug conjugate production for cancer treatment.  PLoS ONE.  13. 2018
2018 Mitochondrial-mediated oxidative Ca2+/calmodulin-dependent kinase II activation induces early afterdepolarizations in Guinea pig cardiomyocytes: An in silico study.  Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.  7. 2018
2018 Mitochondrial Dysfunction-Associated Arrhythmogenic Substrates in Diabetes Mellitus..  Frontiers in Physiology.  9:1670. 2018
2017 Electrophysiological Properties and Viability of Neonatal Rat Ventricular Myocyte Cultures with Inducible ChR2 Expression.  Scientific Reports.  7. 2017
2017 Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy.  Scientific Reports.  7. 2017
2017 Process engineering of cellulosic n-butanol production from corn-based biomass using Clostridium cellulovorans.  Process Biochemistry.  62:144-150. 2017
2017 The amyloid precursor protein modulates α2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.  Federation proceedings.  31:4434-4446. 2017
2017 Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α2A adrenergic receptor ligands.  Neuropharmacology.  116:38-49. 2017
2017 Comparative proteomic analysis of three Chinese hamster ovary (CHO) host cells.  Microbial Genomics.  124:122-129. 2017
2016 Impaired mitochondrial network excitability in failing Guinea-pig cardiomyocytes.  Journal of Nonprofit and Public Sector Marketing.  109:79-89. 2016
2015 High-level expression of recombinant IgG1 by CHO K1 platform.  Frontiers of Chemical Science and Engineering.  9:376-380. 2015
2015 Cardiomyocyte mitochondrial oxidative stress and cytoskeletal breakdown in the heart with a primary volume overload.  Journal of Mid-Life Health.  308:H651-H663. 2015
2015 Cardiomyocyte mitochondrial oxidative stress and cytoskeletal breakdown in the heart with a primary volume overload.  Journal of Mid-Life Health.  308:H651-H663. 2015
2015 Mitochondria-derived ROS bursts disturb Ca2+ cycling and induce abnormal automaticity in guinea pig cardiomyocytes: A theoretical study.  Journal of Mid-Life Health.  308:H623-H636. 2015
2015 Comparative proteomics analysis of high n-butanol producing metabolically engineered Clostridium tyrobutyricum.  Journal of Biotechnology.  193:108-119. 2015
2014 Targeted biopharmaceuticals for cancer treatment.  Journal of Peptide Science.  352:145-151. 2014
2014 High-fat, low-carbohydrate diet promotes arrhythmic death and increases myocardial ischemia-reperfusion injury in rats.  Journal of Mid-Life Health.  307. 2014
2014 Stromal interaction molecule 1 is essential for normal cardiac homeostasis through modulation of ER and mitochondrial function.  Journal of Mid-Life Health.  306. 2014
2014 Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes.  PLoS ONE.  9. 2014
2014 Effects of regional mitochondrial depolarization on electrical propagation: Implications for arrhythmogenesis.  International Journal of Bio-Science and Bio-Technology.  7:143-151. 2014
2013 HNO Enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization.  Acta Chimica Slovenica.  19:1185-1197. 2013
2012 Cardiac mitochondrial network excitability: Insights from computational analysis.  Journal of Mid-Life Health.  302. 2012
2011 Dynamic modulation of Ca2+ sparks by mitochondrial oscillations in isolated guinea pig cardiomyocytes under oxidative stress.  Journal of Molecular and Cellular Cardiology.  51:632-639. 2011
2010 A reaction-diffusion model of ROS-induced ROS release in a mitochondrial network.  PLoS Computational Biology.  6. 2010
2009 Modeling cardiac action potential shortening driven by oxidative stress-induced mitochondrial oscillations in guinea pig cardiomyocytes.  Journal of Human Lactation.  97:1843-1852. 2009
2009 From mitochondrial dynamics to arrhythmias.  The International journal of biochemistry.  41:1940-1948. 2009
2008 From mitochondrial ion channels to arrhythmias in the heart: Computational techniques to bridge the spatio-temporal scales.  Philosophical Transactions A: Mathematical, Physical and Engineering Sciences.  366:3381-3409. 2008
2008 Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia.  Journal of Theoretical Biology.  254:466-475. 2008
2008 Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia.  Journal of Mid-Life Health.  295. 2008
2008 Metabolic response to an acute jump in cardiac workload: Effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation.  Journal of Mid-Life Health.  294. 2008
2007 Parallel activation of mitochondrial oxidative metabolism with increased cardiac energy expenditure is not dependent on fatty acid oxidation in pigs.  Journal of Physiology.  579:811-821. 2007
2006 Regulation of myocardial substrate metabolism during increased energy expenditure: Insights from computational studies.  Journal of Mid-Life Health.  291. 2006
2006 Role of cellular compartmentation in the metabolic response to stress: Mechanistic insights from computational models.  Onkologie.  1080:120-139. 2006
2005 Regulation of lactate production at the onset of ischaemia is independent of mitochondrial NADH/NAD+: Insights from in silico studies.  Journal of Physiology.  569:925-937. 2005
2005 Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia.  Journal of Mid-Life Health.  288. 2005
2005 Regulation of cardiac energetics: Role of redox state and cellular compartmentation during ischemia.  Onkologie.  1047:259-270. 2005

Education And Training

  • Doctor of Philosophy in Biomedical / Medical Engineering, Case Western Reserve University 2006

    • Full Name

  • Lufang Zhou