Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Prenatal epigenetics diets play protective roles against environmental pollution.  Clinical Epigenetics.  11. 2019
2018 Temporal efficacy of a sulforaphane-based broccoli sprout diet in prevention of breas cancer through modulation of epigenetic mechanisms.  Cancer Prevention Research.  11:451-464. 2018
2018 The effects of combinatorial genistein and sulforaphane in breast tumor inhibition: Role in epigenetic regulation.  International Journal of Molecular Sciences.  19. 2018
2017 Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression.  Scientific Reports.  7. 2017
2017 Impact of genistein on the gut microbiome of humanized mice and its role in breast tumor inhibition.  PLoS ONE.  12. 2017
2016 Age-related epigenetic drift and phenotypic plasticity loss: Implications in prevention of age-related human diseases.  Epigenomics.  8:1637-1651. 2016
2016 Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals.  Epigenomics.  8:1019-1037. 2016
2014 Impact of epigenetic dietary compounds on transgenerational prevention of human diseases 2014
2013 Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.  Experimental Cell Research.  319:697-706. 2013
2013 Epigenetic reactivation of estrogen receptor-α (ERα) by genistein enhances hormonal therapy sensitivity in ERα-negative breast cancer.  Molecular Cancer.  12. 2013
2013 Epigenetic Regulation of Multiple Tumor-Related Genes Leads to Suppression of Breast Tumorigenesis by Dietary Genistein.  PLoS ONE.  8. 2013
2013 Analysis of biomarkers of caloric restriction in aging cells.  Methods in Molecular Biology.  1048:19-29. 2013
2013 Cell senescence culturing methods.  Methods in Molecular Biology.  1048:1-10. 2013
2013 Enhancement of cisplatin-mediated apoptosis in ovarian cancer cells through potentiating G2/M arrest and p21 upregulation by combinatorial epigallocatechin gallate and sulforaphane.  Journal of Oncology.  2013
2012 Bioactive dietary supplements reactivate ER expression in ER-negative breast cancer cells by active chromatin modifications.  PLoS ONE.  7. 2012
2012 Epigenetic food: a new approach for cancer prevention and therapy..  J. of Nutrition & Food Sciences.  1000E. 2012
2012 Potential of resveratrol in inhibiting cancer and slowing aging..  J. of Nutrition & Food Sciences.  S5001. 2012
2011 Combined chromatin immunoprecipitation and bisulfite methylation sequencing analysis.  Methods in Molecular Biology.  791:239-251. 2011
2011 DNA methylation detection: Bisulfite genomic sequencing analysis.  Methods in Molecular Biology.  791:11-21. 2011
2011 Epigenetic regulation of caloric restriction in aging.  BMC Medicine.  9. 2011
2011 Insufficient DNA methylation affects healthy aging and promotes age-related health problems.  Clinical Epigenetics.  2:349-360. 2011
2011 P16INK4A suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms.  PLoS ONE.  6. 2011
2011 2D difference gel electrophoresis analysis of different time points during the course of neoplastic transformation of human mammary epithelial cells.  Journal of Proteome Research.  10:447-458. 2011
2011 A novel tumor suppressor gene ECRG4 interacts directly with TMPRSS11A (ECRG1) to inhibit cancer cell growth in esophageal carcinoma.  BMC Cancer.  11. 2011
2010 Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells.  Molecular Cancer.  9. 2010
2010 Glucose restriction can extend normal cell lifespan and impair precancerous cell growth through epigenetic control of hTERT and p16 expression.  The FASEB Journal.  24:1442-1453. 2010
2010 Impact on DNA methylation in cancer prevention and therapy by bioactive dietary components.  Current Medicinal Chemistry.  17:2141-2151. 2010
2009 Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms.  International Journal of Cancer.  125:286-296. 2009
2009 Strategies targeting telomerase inhibition.  Molecular Biotechnology.  41:194-199. 2009
2008 Gene-environment interactions and epigenetic basis of human diseases.  Current Issues in Molecular Biology.  10:25-36. 2008
2007 ECRG2 inhibits cancer cell migration, invasion and metastasis through the down-regulation of uPA/plasmin activity..  Carcinogenesis.  28:2274-2281. 2007
2006 Identification of a novel polymorphism Arg290Gln of esophageal cancer related gene 1 ( ECRG1 ) and its related risk to esophageal squamous cell carcinoma.  Carcinogenesis.  27:798-802. 2006
2005 Monoclonal antibodies to esophageal cancer-related gene2 protein.  Hybridoma.  24:86-91. 2005

Chapter

Year Title Altmetric
2015 Transgenerational epigenetic regulation by environmental factors in human diseases.  209-222. 2015
2010 Dietary effect on epigenetics during the aging process.  407-416. 2010

Full Name

  • Yuanyuan Li