Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's diseaseBBA - Molecular Basis of Disease.  1863:1157-1170. 2017
2015 Distinct effects of ubiquitin overexpression on NMJ structure and motor performance in mice expressing catalytically inactive USP14Frontiers in Molecular Neuroscience.  8. 2015
2015 Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junctionMolecular Neurodegeneration.  10. 2015
2015 Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGSPLoS Genetics.  11. 2015
2014 A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short-term plasticity and vesicle numberJournal of Physiology.  592:571-586. 2014
2013 Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (Usp14)PLoS ONE.  8. 2013
2013 The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formationLearning and Memory.  21:748-752. 2013
2013 Neuronal Ubiquitin HomeostasisCell Biochemistry and Biophysics.  67:67-73. 2013
2012 Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent DeficitsPLoS ONE.  7. 2012
2012 Altered neurotransmitter release machinery in mice deficient for the deubiquitinating enzyme Usp14American Journal of Physiology - Cell Physiology.  302:C698-C708. 2012
2011 Ubiquitin homeostasis is critical for synaptic development and functionJournal of Neuroscience.  31:17505-17513. 2011
2010 Enhancement of proteasome activity by a small-molecule inhibitor of USP14Nature.  467:179-184. 2010
2009 The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctionsJournal of Neuroscience.  29:10909-10919. 2009
2009 Regulation of Synaptic Structure by Ubiquitin C-Terminal Hydrolase L1Journal of Neuroscience.  29:7857-7868. 2009
2009 The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in micePLoS Genetics.  5. 2009
2009 Transgenic rescue of ataxia mice reveals a male-specific sterility defectDevelopmental Biology.  325:33-42. 2009
2008 Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activityMolecular and Cellular Neuroscience.  39:539-548. 2008
2008 Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.Molecular Brain.  1:17. 2008
2006 Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14Journal of Neuroscience.  26:11423-11431. 2006
2005 Loss of Usp14 results in reduced levels of ubiquitin in ataxia miceJournal of Neurochemistry.  95:724-731. 2005
2003 Neurological disease: UPS stops delivering!Trends in Pharmacological Sciences.  24:18-23. 2003
2002 Synaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific proteaseNature Genetics.  32:420-425. 2002
2002 Dual requirement for yeast hnRNP Nab2p in mRNA poly(A) tail length control and nuclear exportEMBO Journal.  21:1800-1810. 2002
2001 Mutations in Cdh23 Cause Nonsyndromic Hearing Loss in waltzer MiceGenomics.  74:228-233. 2001
2001 Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activityFederation proceedings.  15:1288-1290. 2001
2000 A mutation in Rab27a causes the vesicle transport defects observed in ashen miceProceedings of the National Academy of Sciences.  97:7933-7938. 2000
2000 A yeast heterogeneous nuclear ribonucleoprotein complex associated with RNA polymerase IIGenetics.  154:557-571. 2000
2000 The status of voltage-dependent calcium channels in alpha 1E knock-out miceJournal of Neuroscience.  20:8566-8571.. 2000
1994 Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiaeJournal of Cell Biology.  127:1173-1184. 1994
1993 NAB2: a yeast nuclear polyadenylated RNA-binding protein essential for cell viability.Molecular and Cellular Biology.  13:2730-2741. 1993
1992 Legionella pneumophilia infection and cytokine productionAdvances in Experimental Medicine and Biology.  319. 1992

Teaching Activities

  • NBL433 - Diseases of the Nervous System (Fall Term 2019) 2019
  • NBL633 - Diseases of the Nervous System (Fall Term 2019) 2019
  • NBL401 - Collo in Basic Cog & Clin Neur (Fall Term 2017) 2017
  • NBL398 - Rescg Prac in Neurobiology-RES (Summer Term 2017) 2017
  • NBL240 - Special Topics Neuroscience 3 (Spring Term 2017) 2017
  • NBL398 - Rescg Prac in Neurobiology-RES (Spring Term 2017) 2017
  • NBL398 - Rescg Prac in Neurobiology-RES (Spring Term 2017) 2017
  • NBL399 - Senior Seminar in Neuroscience (Spring Term 2017) 2017
  • NBL401 - Collo in Basic Cog & Clin Neur (Spring Term 2017) 2017
  • NBL773 - Neuronal Signaling JC (Spring Term 2017) 2017
  • PY401 - Neuroscience Seminar (Spring Term 2017) 2017
  • STH201 - Research Approaches (Spring Term 2017) 2017
  • NBL398 - Rescg Prac in Neurobiology-RES (Fall Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Fall Term 2016) 2016
  • NBL399 - Senior Seminar in Neuroscience (Fall Term 2016) 2016
  • NBL399 - Senior Seminar in Neuroscience (Fall Term 2016) 2016
  • NBL401 - Collo in Basic Cog & Clin Neur (Fall Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Summer Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Summer Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Spring Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Spring Term 2016) 2016
  • NBL399 - Senior Seminar in Neuroscience (Spring Term 2016) 2016
  • NBL399 - Senior Seminar in Neuroscience (Spring Term 2016) 2016
  • NBL773 - Neuronal Signaling JC (Spring Term 2016) 2016
  • NBL398 - Rescg Prac in Neurobiology-RES (Fall Term 2015) 2015
  • NBL399 - Senior Seminar in Neuroscience (Fall Term 2015) 2015
  • GBS784 - STEM CELL BIOLOGY (Spring Term 2015) 2015
  • NBL773 - Neuronal Signaling JC (Spring Term 2015) 2015
  • GBS791 - GRADUATE NEUROSCIENCE DISCUSSION (Spring Term 2013) 2013
  • GBS791 - Grad Neuro Discussion (Spring Term 2012) 2012
  • NBL712 - Graduate Medical Neuroscience (Spring Term 2011) 2011
  • GBS732 - GRADUATE NEUROSCIENCE DISCUSSION (Spring Term 2011) 2011
  • NBL712 - Graduate Medical Neuroscience (Spring Term 2010) 2010
  • NEUR725 - Grd Neur Dicussion (Spring Term 2010) 2010
  • NBL725 - Sem Practice in Cell Mol Neuro (Fall Term 2009) 2009
  • CMB790 - CMB Laboratory Methods (Spring Term 2009) 2009
  • NEUR708 - Laboratory Methods (Spring Term 2009) 2009
  • CMB790 - CMB Laboratory Methods (Fall Term 2008) 2008
  • CMB790 - CMB Laboratory Methods (Spring Term 2008) 2008
  • CMB790 - CMB Laboratory Methods (Fall Term 2007) 2007
  • Education And Training

  • Doctor of Philosophy in Genetics, University of Florida 1996
  • Full Name

  • Scott Wilson