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Karina Yoon Ph.D.
Associate Professor
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E-mail
kyoon@uab.edu
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Karina Yoon Ph.D.
Associate Professor
Positions
Scientist
,
Cancer Cell Biology
,
O'Neal Comprehensive Cancer Center
Associate Professor (P)
,
Pharmacology and Toxicology
,
Academic Joint Departments
2009 -
Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
2009 -
Associate Scientist (C)
,
Comprehensive Neuroscience Center
,
General Clinical Research Center
2014 -
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2020
The combination of BET and PARP inhibitors is synergistic in models of cholangiocarcinoma
.
Cancer Letters
. 468:48-58.
2020
2019
The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors
.
EBioMedicine
. 44:419-430.
2019
2018
FTY720 enhances the anti-tumor activity of carboplatin and tamoxifen in a patient-derived xenograft model of ovarian cancer
.
Cancer Letters
. 436:75-86.
2018
2018
Pediatric anaplastic embryonal rhabdomyosarcoma: Targeted therapy guided by genetic analysis and a patient-derived xenograft study
.
Frontiers in Oncology
. 7.
2018
2016
The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype
.
Cancer Research
. 76:3978-3988.
2016
2013
N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells
.
BMC Cancer
. 13.
2013
2009
Cell adhesion molecules as targets for therapy of neuroblastoma.
.
Cancer Biology and Therapy
. 8:306-311.
2009
2007
Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma
.
Cancer Research
. 67:22-25.
2007
2005
Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11.
.
Chemico-Biological Interactions
. 157-158:247-252.
2005
2005
Development of prodrugs for enzyme-mediated, tumor-selective therapy.
2005
2003
Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism
.
Bioorganic and Medicinal Chemistry
. 11:3237-3244.
2003
Research
Principal Investigator On
Developing Novel Combination Therapies for Pancreatic Cancer
awarded by
National Cancer Institute/NIH/DHHS
2016 - 2021
Developing Therapy for the Treatment of Cholangiocarcinoma
awarded by
National Cancer Institute/NIH/DHHS
2016 - 2019
Investigator On
Role of PIM Kinase in Maintaining Hepatoblastoma Tumor Initiating Cell Population
awarded by
KAUL PEDIATRIC RESEARCH INSTITUTE
2017 - 2019
Glycan Control of Stem Cell-Associated Pathways in Pancreatic Cancer
awarded by
National Cancer Institute/NIH/DHHS
2015 - 2017
Teaching
Teaching Activities
MBS613 - Systems Pharmacology II (Summer Term 2020)
2020
GBS753 - Pharm Tox & Molec Med (Spring Term 2020)
2020
GBS775 - Cancer Treatment (Spring Term 2020)
2020
GBSC720 - Journal Club 2 (Spring Term 2020)
2020
GBSC720 - Journal Club 2 (Fall Term 2019)
2019
MBS613 - Systems Pharmacology II (Summer Term 2019)
2019
GBS753 - Pharmacology & Molec Med (Spring Term 2019)
2019
GBSC720 - Journal Club 2 (Spring Term 2019)
2019
GBSC720 - Journal Club 2 (Fall Term 2018)
2018
GBS753 - Pharm & Molec Med (Spring Term 2018)
2018
GBS775 - Cancer Treatment (Spring Term 2018)
2018
GBS753 - Pharm & Molec Med (Spring Term 2017)
2017
GBS703 - Res Analysis & Presentation (Fall Term 2016)
2016
GBS753 - Pharm & Molec Med (Spring Term 2016)
2016
GBS775 - Cancer Treatment (Spring Term 2016)
2016
GBS753 - Pharm & Molec Med (Spring Term 2015)
2015
GBS775 - Cancer Treatment (Spring Term 2014)
2014
GBS775 - Cancer Treatment (Fall Term 2011)
2011
Background
Education And Training
Doctor of Philosophy in Pharmacology,
Florida Agricultural & Mechanical University
2001
Contact
Full Name
Karina
Yoon