Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Human leukocyte antigen class I and II knockout human induced pluripotent stem cell–derived cells: Universal donor for cell therapy 2018
2018 Defining the epigenetic status of blood cells using a cyanine-based fluorescent probe for PRMT1 2018
2018 Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis 2018
2018 Bone Marrow Transplantation after Nonmyeloablative Treosulfan Conditioning Is Curative in a Murine Model of Sickle Cell Disease 2018
2016 Novel HDAd/EBV Reprogramming Vector and Highly Efficient Ad/CRISPR-Cas Sickle Cell Disease Gene Correction 2016
2016 The AS-RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation 2016
2015 Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting 2015
2012 Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells 2012
2012 SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency 2012
2011 PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprograming 2011
2010 KLF1 regulates BCL11A expression and γ- to β-globin gene switching 2010
2009 Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells 2009
2008 SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation 2008
2006 Correction of sickle cell disease by homologous recombination in embryonic stem cells 2006
2006 Differential binding of erythroid krupple-like factor to embryonic/fetal globin gene promoters during development 2006
2003 Correction of a mouse model of sickle cell disease: Lentiviral/ antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells 2003
2000 Generation of novel embryonic stem cell lines from knockout-transgenic sickle cell disease mice: a new tool for therapeutic intervention 2000
1995 Autonomous, erythroid-specific DNAse I hypersensitive site formed by human β-globin locus control region (LCR) 5' HS 2 in transgenic mice 1995
1995 End joining of genomic DNA and transgene DNA in fertilized mouse eggs 1995
1991 Human β-globin locus control region: Analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice 1991

Full Name

  • Kevin Pawlik