Selected Publications

Academic Article

Year Title Altmetric
2016 Adipose-derived mesenchymal stem cells restore impaired mucosal immune responses in aged mice 2016
2014 A recombinant adenovirus-based vector elicits a specific humoral immune response against the V3 loop of HIV-1 gp120 in mice through the "antigen Capsid-Incorporation" strategy 2014
2012 A novel combined adjuvant for nasal delivery elicits mucosal immunity to influenza in aging 2012
2012 Intranasal administration of a flagellin-adjuvanted inactivated influenza vaccine enhances mucosal immune responses to protect mice against lethal infection 2012
2011 Mucosal immune features to phosphorylcholine by nasal Flt3 ligand cDNA-based vaccination 2011
2010 Indigenous opportunistic bacteria inhabit mammalian gut-associated lymphoid tissues and share a mucosal antibody-mediated symbiosis 2010
2009 A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota 2009
2009 Oral MucoRice expressing double-mutant cholera toxin A and B subunits induces toxin-specific neutralising immunity 2009
2009 Co-administration of cholera toxin and apple polyphenol extract as a novel and safe mucosal adjuvant strategy 2009
2008 A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity 2008
2007 Long- and short-time immunological memory in different strains of mice given nasally an adjuvant-combined nasal influenza vaccine 2007
2007 A single intranasal immunization with inactivated influenza virus and α-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system 2007
2002 A dilemma for mucosal vaccination: Efficacy versus toxicity using enterotoxin-based adjuvants 2002
2002 Effects of Self-Etching Primer, Adhesive, NaOCl and H_2O_2 on Lymphocytes : In Vitro Model 2002
2001 Highly purified mutant E112K of cholera toxin elicits protective lung mucosal immunity to diphtheria toxin 2001
2001 Peyer's patches are required for oral tolerance to proteins 2001
2001 Nasal immunization with E. coli verotoxin 1 (VT1)-B subunit and a nontoxic mutant of cholera toxin elicits serum neutralizing antibodies 2001
2001 Peyer's patches are required for oral tolerance to proteins 2001
2000 Mucosal vaccination and immune responses in the elderly 2000
1998 Immune Responses against Outer Membrane Protein P6 of Nontypeable Haemophilus influenzae 1998
1997 A T cell/B cell/epithelial cell internet for mucosal inflammation and immunity 1997
1997 A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity 1997
1996 Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on γδ T-cell receptor-positive intraepithelial lymphocytes 1996
1994 Helper Th1 and Th2 cell responses following mucosal or systemic immunization with cholera toxin 1994
1994 The common mucosal immune system: From basic principles to enteric vaccines with relevance for the female reproductive tract 1994
1993 New perspectives in mucosal immunity with emphasis on vaccine development. 1993
1993 Cytokine profiles of bronchoalveolar lavage cells from mice with influenza pneumonia: Consequences of CD4+ and CD8+ T cell depletion 1993
1992 Effects of IL6 on B cells in mucosal immune response and inflammation 1992
1992 Regulation of mucosal immune responses by T lymphocytes: The effect of chronic CD4+T cell deficiency on IgA synthesis 1992
1992 The use of the hu-PBL-SCID mouse model to study lymphocyte homing and responsiveness to recall antigens 1992


Year Title Altmetric
2012 Host defenses at mucosal surfaces.  239-251. 2012
2008 Host defenses at mucosal surfaces.  287-303. 2008
2005 Collection and processing of external secretions and tissues of mouse origin.  1841-1852. 2005
2005 Th1/Th2/Th3 cells for regulation of mucosal immunity, tolerance, and inflammation.  539-558. 2005
1997 Mucosal immunity and gnotobiology: Past accomplishments help point to future needs.  209-13. 1997
1996 Regulation of mucosal immune responses by helper T cells and cytokines.  62-81. 1996

Education And Training

  • Doctor of Philosophy in Immunology, Osaka Dental University 1994
  • Full Name

  • Kohtaro Fujihashi