Dr. Knight’s laboratory is focused on better understanding the neural substrates of human learning, memory, and emotion using magnetic resonance imaging (MRI) techniques that include functional MRI, diffusion tensor imaging, and magnetic resonance spectroscopy. Behavioral and MRI studies from the lab investigate questions that are important for understanding healthy, as well as dysfunctional, emotion processes.
Recent work from the Knight lab has investigated the neural circuitry that supports emotion regulation processes. Disruption of these processes appears to play an important role in the emotional dysfunction associated with mood and anxiety disorders. Studies from the Knight lab will help determine neural mechanisms that mediate susceptibility/resilience to stress, and offer insights into the development of emotion-related disorders.