Positions

Selected Publications

Academic Article

Year Title Altmetric
2014 Heat-shock response increases lung injury caused by pseudomonas aeruginosa via an Interleukin-10-dependent mechanism in miceAnesthesiology.  120:1450-1462. 2014
2011 Cytoprotective-selective activated protein C attenuates pseudomonas aeruginosa - Induced lung injury in miceAmerican Journal of Respiratory Cell and Molecular Biology.  45:632-641. 2011
2007 Glutathione suppresses TGF-β-induced PAI-1 expression by inhibiting p38 and JNK MAPK and the binding of AP-1, SP-1, and Smad to the PAI-1 promoter 2007
2006 4-Hydroxynonenal induces rat γ-glutamyl transpeptidase through mitogen-activated protein kinase-mediated electrophile response element/nuclear factor erythroid 2-related factor 2 signalingAmerican Journal of Respiratory Cell and Molecular Biology.  34:174-181. 2006
2004 Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stressArchives of Biochemistry and Biophysics.  423:116-125. 2004
2003 Cytoprotection against oxidative stress and the regulation of glutathione synthesis 2003
2002 A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile. 2002
2002 A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile 2002
2002 Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinaseArchives of Biochemistry and Biophysics.  405:231-240. 2002

Chapter

Year Title Altmetric
2016 Carcinogens, Environmental.  422-437. 2016
2016 Environmental Health: Overview.  487-498. 2016
2011 Glutathione.  3-20. 2011

Education And Training

  • Doctor of Philosophy Level Degree in Nutrition Sciences, 1998
  • Master's Level Degree in Biology / Biological Sciences, 1994
  • Bachelor's Level Degree in Biology / Biological Sciences, 1992
  • Full Name

  • Karen Iles