Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 The role of the gut microbiota on the metabolic status of obese children 2021
2021 Proinsulin to C-Peptide Ratio in the First Year after Diagnosis of Type 1 DiabetesJournal of Clinical Endocrinology and Metabolism.  106:E4318-E4326. 2021
2021 PATRO children, a multi-center, non-interventional study of the safety and effectiveness of Omnitrope®(somatropin) treatment in children: Update on the United States cohortJournal of Pediatric Endocrinology and Metabolism.  34:431-440. 2021
2021 Gut Microbiota of Chinese Obese Children and Adolescents With and Without Insulin ResistanceFrontiers in Endocrinology.  12. 2021
2021 Hepatic endoplasmic reticulum calcium fluxes: Effect of free fatty acids and katp channel involvement 2021
2020 Fragile Bones Secondary to SMURF1 Gene DuplicationCalcified Tissue International.  106:567-573. 2020
2020 Temporal trends in incidence of pediatric type 1 diabetes in Alabama: 2000-2017Pediatric Diabetes.  21:40-47. 2020
2019 Authors’ Reply: Pyridine nucleotide regulation of hepatic endoplasmic reticulum calcium uptakePhysiological Reports.  7. 2019
2019 Effect of gamma aminobutyric acid (GABA) or GABA with glutamic acid decarboxylase (GAD) on the progression of type 1 diabetes mellitus in children: Trial design and methodologyContemporary Clinical Trials.  82:93-100. 2019
2019 Pyridine nucleotide regulation of hepatic endoplasmic reticulum calcium uptakePhysiological Reports.  7. 2019
2016 Increased cord blood betatrophin levels in the offspring of mothers with gestational diabetesPLoS ONE.  11. 2016
2016 Effect of n-3 and n-6 polyunsaturated fatty acids on microsomal P450 steroidogenic enzyme activities and in vitro cortisol production in adrenal tissue from yorkshire boarsEndocrinology.  157:1512-1521. 2016
2016 Cortisol promotes endoplasmic glucose production via pyridine nucleotide redoxJournal of Endocrinology.  229:25-36. 2016
2015 Hypomagnesemia due to two novel TRPM6 mutationsJournal of Pediatric Endocrinology and Metabolism.  28:1373-1378. 2015
2015 Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individualsJournal of Clinical and Translational Endocrinology.  2:77-82. 2015
2015 Placental DNA methylation of peroxisome-proliferator-activated receptor-γ co-activator-1α promoter is associated with maternal gestational glucose levelClinical Science.  129:385-394. 2015
2014 Lipid patterns in treated growth hormone deficient children vs. short stature controlsJournal of Pediatric Endocrinology and Metabolism.  27:909-914. 2014
2014 Antimüllerian hormone as a measure of reproductive function in female childhood cancer survivorsFertility and Sterility.  101:227-231. 2014
2013 Evidence that adrenal hexose-6-phosphate dehydrogenase can effect microsomal P450 cytochrome steroidogenic enzymes 2013
2012 Effect of cinacalcet on cardiovascular disease in patients undergoing dialysisNew England Journal of Medicine.  367:2482-2494. 2012
2012 Associations between salivary testosterone and cortisol levels and neonatal health and growth outcomesEarly Human Development.  88:789-795. 2012
2011 Associations of serum 25-hydroxyvitamin d and components of the metabolic syndrome in obese adolescent females 2011
2011 Changes in plasma FGF23 in growth hormone deficient children during rhGH therapyJournal of Pediatric Endocrinology and Metabolism.  24:645-650. 2011
2011 Manifold effects of palmitoylcarnitine on endoplasmic reticulum metabolism: 11β-hydroxysteroid dehydrogenase 1, flux through hexose-6-phosphate dehydrogenase and NADPH concentrationBiochemical Journal.  437:109-115. 2011
2010 Effect of diabetes on enzymes involved in rat hepatic corticosterone productionJournal of Diabetes.  2:275-281. 2010
2010 Dietary iron intake in the first 4 months of infancy and the development of type 1 diabetes: A pilot study 2010
2010 Bicalutamide plus Anastrozole for the Treatment of Gonadotropin-Independent Precocious Puberty in Boys with Testotoxicosis: A Phase II, Open-Label Pilot Study (BATT)Journal of Pediatric Endocrinology and Metabolism.  23:999-1009. 2010
2009 Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasiaJournal of Clinical Endocrinology and Metabolism.  94:17-20. 2009
2009 Racial disparities on glycemic control and lipid profiles in children with type 1 diabetesClinical Medicine Insights: Endocrinology and Diabetes.  2009:1-6. 2009
2009 Threshold for effects of vitamin D deficiency on glucose metabolism in obese female African-American adolescentsJournal of Clinical Endocrinology and Metabolism.  94:3200-3206. 2009
2008 Modification of microsomal 11β-HSD1 activity by cytosolic compounds: Glutathione and hexose phosphoesters 2008
2008 Tumoral calcinosis: An unusual etiologyEndocrinologist.  18:191-194. 2008
2007 Insulin treatment reduces pre-prandial plasma ghrelin concentrations in children with type 1 diabetes 2007
2006 Evidence that the 11 β-hydroxysteroid dehydrogenase (11 β-HSD1) is regulated by pentose pathway flux: Studies in rat adipocytes and microsomesJournal of Biological Chemistry.  281:341-347. 2006
2006 Bronchiolitis with hyponatremia: CommentaryClinical Pediatrics.  45:102-103. 2006
2006 Growth hormone-IGF-I axis and growth velocity in Chinese children with type 1 diabetes mellitusJournal of Pediatric Endocrinology and Metabolism.  19:1313-1318. 2006
2006 Prevalence of hypovitaminosis D in early infantile hypocalcemiaJournal of Pediatric Endocrinology and Metabolism.  19:1025-1031. 2006
2005 Effect of insulin on plasma vascular endothelial growth factor in children with new-onset diabetesJournal of Clinical Endocrinology and Metabolism.  90:4920-4923. 2005
2004 Hyperreninemia and hypoaldosteronism in a child with short statureEndocrinologist.  14:313-316. 2004
2003 Nutritional regulation of white adipocyte Vascular Endothelial Growth Factor (VEGF)Hormone and Metabolic Research.  35:211-216. 2003
2002 Effect of oral fluid intake on urinary albumin excretion in diabetes mellitusJournal of Diabetes and its Complications.  16:310-312. 2002
2002 Stature at time of diagnosis of type 1 diabetes mellitusPediatrics.  109:479-483. 2002
2002 White adipocyte vascular endothelial growth factor: Regulation by insulinEndocrinology.  143:948-953. 2002
2001 Leptin in children with newly diagnosed type 1 diabetes: Effect of insulin therapyInternational journal of experimental diabetes research.  2:121-127. 2001
2000 Inhibition of leptin secretion by insulin and metformin in cultured rat adipose tissue 2000
2000 Cord blood and postnatal serum leptin and its relationship to steroid use and growth in sick preterm infantsJournal of Pediatric Endocrinology and Metabolism.  13:1571-1576. 2000
2000 Hyponatremia secondary to reset osmostat in a child with a central nervous system midline defect and a chromosomal abnormalityJournal of Pediatric Endocrinology and Metabolism.  13:1637-1641. 2000
1998 Inhibition of acetyl CoA carboxylase by GTPγS 1998
1998 Leptin does not affect adipocyte glucose metabolism: Studies in fresh and cultured adipocytes 1998
1998 Neonatal cord blood leptin: Its relationship to birth weight, body mass index, maternal diabetes, and steroidsPediatric Research.  43:338-343. 1998
1995 Osteomalacia with hypophosphatemia and hypercalciuria: A possible new variant of osteomalaciaJournal of Pediatrics.  127:105-109. 1995
1994 Persistence of disturbed adipocyte metabolism in sterptozocin-induced diabetic rats despite near-euglycemia with phlorizin 1994
1993 Hypothalamic-Pituitary Dysfunction after Radiation for Brain TumorsNew England Journal of Medicine.  328:87-94. 1993
1993 Hypothalamic-pituitary dysfunction after radiation for brain tumorsObstetrical and Gynecological Survey.  48:428-432. 1993
1992 Activation of in situ glycolytic flux by bisphosphorylated compounds: studies in porous rat adipocytes 1992
1991 Selective stimulation of in situ intermediary metabolism by free calcium in permeabilized rat adipocytes 1991
1991 Highly specific micromethod for the enzymatic determination of radioactive [14C]lactateAnalytical Biochemistry.  192:293-297. 1991
1991 Calculations of "predicted" serum sodium concentration in diabetic ketoacidosisJournal of Pediatrics.  118:166-167. 1991
1991 Diminished in situ glucose-6-phosphate flux in permeabilized adipocytes from streptozocin-induced diabetic ratsDiabetes.  40:1517-1524. 1991
1991 Kinetic superiority of intra- vs. extracellular pentose pathway flux: Studies in porous adipocytesAmerican Journal of Physiology.  261. 1991
1991 Massive breast enlargement in an infant girl with central nervous system dysfunctionEuropean Journal of Pediatrics.  150:154-157. 1991
1991 Profound hypercalcemia and rhabdomyolysis in a childJournal of Pediatric Endocrinology and Metabolism.  4:125-129. 1991
1990 Adjunctive use of tolazamide in newly-diagnosed diabetic childrenHormone and Metabolic Research.  22:576-580. 1990
1990 Normalization of plasma arginine vasopressin concentrations when children with meningitis are given maintenance plus replacement fluid therapyJournal of Pediatrics.  117:515-522. 1990
1988 Carnitine palmitoyltransferase: Effects of diabetes, fasting, and pH on the reaction that generates acyl CoA 1988
1988 Preservation of intermediary metabolism in saponin-permeabilized rat adipocytesJournal of Biological Chemistry.  263:10667-10673. 1988
1987 Pancreatic exocrine aplasia, clinical features of leprechaunism, and abnormal gonadotropin regulation 1987
1986 Effect of tolazamide on basal ketogenesis, glycogenesis, and gluconeogenesis in liver obtained from normal and diabetic ratsEndocrinology.  119:1268-1273. 1986
1986 HYPERPROLACTINAEMIA IN CONGENITAL HYPOTHYROIDISMClinical Endocrinology.  24:285-290. 1986
1985 Fetal rat hyperinsulinism and hyperglucagonism: Effects on hepatic ketogenesis, lipogenesis, and gluconeogenesisEndocrinology.  116:1281-1287. 1985
1985 Partial pyruvate decarboxylase deficiency with profound lactic acidosis and hyperammonemia: Responses to dichloroacetate and benzoate 1985
1984 Thyrotropin (TSH)-induced hyperthyroidism: Response of TSH to dopamine and its agonistsJournal of Clinical Endocrinology and Metabolism.  58:255-261. 1984
1983 Hyperthyroxinemia in Newborns Due to Excess Thyroxine-Binding GlobulinNew England Journal of Medicine.  309:897-899. 1983
1983 Importance of albumin binding in the assay for carnitine palmitoyltransferaseBiochemical Journal.  216:495-498. 1983
1983 Inhibition by acetyl-CoA of hepatic carnitine acyltransferase and fatty acid oxidationBiochemical Journal.  216:499-502. 1983
1982 Inappropriate TSH syndrome: Response to dopaminePediatric Research.  16. 1982
1981 Effects of Insulin on the Biochemical and Morphologic Maturation of the Fetus 1981
1980 Cerebrospinal fluid anion gap in meningitisJournal of Pediatrics.  96:874-876. 1980
1980 Rapid fluctuations in glycohemoglobin (hemoglobin AIc) related to acute changes in glucose 1980
1980 Subclinical hepatic changes in varicella infectionPediatrics.  65:631-633. 1980
1979 Chronic hyperinsulinemia in the fetal rhesus monkey. Effects on fetal growth and compositionDiabetes.  28:1058-1063. 1979
1979 Chronic hyperinsulinemia in the fetal rhesus monkey. Effects on hepatic enzymes active in lipogenesis and carbohydrate metabolismDiabetes.  28:1064-1068. 1979
1978 Effects of chronic hyperinsulinaemia on hepatic enzymes involved in lipogenesis and carbohydrate metabolism in the young ratBiochemical Journal.  172:327-331. 1978

Principal Investigator On

  • Assessment of Unmethylated Insulin DNA with Droplet Digital PCR in Adolescents with Type 2 Diabetes and its Relationship to Mixed Meal Tolerance Testing  awarded by Louisiana State University
  • Effect of GABA or combination GABA/GAD on the progressin of type 1 Diabetes Mellitus in Children  awarded by Juvenile Diabetes Research Foundation International
  • Natural History Study of the Development of Type 1 Diabetes  awarded by UNIVERSITY OF SOUTH FLORIDA
  • Private Grant  awarded by Pfizer Pharmaceuticals
  • Private Grant  awarded by ASTRAZENECA INTERNATIONAL
  • Private Grant  awarded by Genentech
  • Private Grant  awarded by NOVO NORDISK PHARMACEUTICALS, INC.
  • Private Grant  awarded by ASTRAZENECA INTERNATIONAL
  • Private Grant  awarded by NOVO NORDISK PHARMACEUTICALS, INC.
  • Private Grant  awarded by ABBOTT LABORATORIES
  • Private Grant  awarded by TEVA NEUROSCIENCE, INC.
  • Private Grant  awarded by MEDTRONIC DIABETES
  • Private Grant  awarded by Genentech
  • Private Grant  awarded by ENDO PHARMACEUTICALS
  • Private Grant  awarded by NOVO NORDISK PHARMACEUTICALS, INC.
  • Private Grant  awarded by SANDOZ PHARMACEUTICAL
  • Private Grant  awarded by DIAMYD MEDICAL AB
  • Private Grant  awarded by DIAMYD MEDICAL AB
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC.
  • Private Grant  awarded by DIAMYD MEDICAL AB
  • Private Grant  awarded by RARE THYROID THERAPEUTICS INTERNATIONAL AB
  • Private Grant  awarded by RARE THYROID THERAPEUTICS INTERNATIONAL AB
  • Use of Aromatase Inhibitors in Boys With Premature Adrenarche and Advanced Bone Age  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE
  • Investigator On

  • Analysis of Human and Mouse Antibodies to Beta Cell Antigens Bearing N-Acetyl Glucosamine Post-Translation Modifications and their Potential to Prevent Human Type 1 Diabetes  awarded by Juvenile Diabetes Research Foundation International
  • Contribution of ß-Cell- & Immune Cell-Derived Lipids to ß-Cell Death and Diabetes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Effect of GABA or Combination GABA/GAD on the Progression of Type 1 Diabetes Mellitus in Children  awarded by Juvenile Diabetes Research Foundation International
  • Natural Antibody Idiotopes as Biomarkers for Progression in The At-risk Setting for Type 1 Diabetes  awarded by Juvenile Diabetes Research Foundation International
  • Private Grant  awarded by ELI LILLY AND COMPANY
  • Private Grant  awarded by BRISTOL MYERS SQUIBB PHARMACEUTICAL COMPANY
  • Private Grant  awarded by MERCK SHARP & DOHME CORP
  • Private Grant  awarded by MERCK SHARP & DOHME CORP
  • Private Grant  awarded by BRISTOL MYERS SQUIBB PHARMACEUTICAL COMPANY
  • Private Grant  awarded by VERSARTIS INC.
  • Private Grant  awarded by DIAMYD MEDICAL AB
  • Private Grant  awarded by VERSARTIS INC.
  • Private Grant  awarded by ASCENDIS PHARMA A/S
  • Private Grant  awarded by ASCENDIS PHARMA A/S
  • Redox Regulation of Anti-Viral Responses in Type 1 Diabetes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
  • Testosterone and Cortisol Levels in Infant Health and Development  awarded by National Institute of Child Health and Human Development/NIH/DHHS
  • Teaching Activities

  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2009)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2009)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2009)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2009)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2009)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Fall Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2007)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2008)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2008)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2010)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2011)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • 52-404 - CLINICAL PEDIATRIC ENDOCRINOLOGY (Spring Term 2012)
  • Education And Training

  • Case Western Reserve University, Residency
  • Rhode Island Hospital, Postdoctoral Fellowship
  • Doctor of Medicine, University of Rochester 1974
  • Full Name

  • Kenneth McCormick