My personal research remains in the steady pursuit to understand Th and Treg cell function, differentiation and trafficking during over-active immune responses: allergic asthma, lupus, colitis, and EAE. Most recently, my interests are pursuing the delineation of Th cell function while applying a stressor, such as exercise. I hope to extend our current knowledge of psycho-neuroimmunolgy by elucidating the intracellular modifications that result in altered Th and Treg cell activation/differentiation thresholds along with differences in T regulatory cell population numbers and potency during chronic activation of adrenergic receptors.
Most recently, I have expanded my studies to include the role of stress and/or exercise in Th and Treg cell migration patterns within the pancreatic adenocarcinoma tumor microenvironment.
It is my intention to train undergraduates in basic laboratory research and to teach portions of the Biomedical Science core curriculum. Student research experiences focus on learning Th cell culture techniques and Th cell-mediated over-active immune response animal science models. Students are encouraged to design experiments, utilize current literature and execute appropriate controls while in training. Promising projects are published in peer-reviewed journals and presented at national conferences. While teaching undergraduates, their coursework is complied of Intro to Pharmacology, focusing on drug design and drug mechanism of action; along with Molecular Basis of Human Genomics, focusing on the genetic origins of human disease, personalized medicine, usage of public bioinformatic databases/software and genetic laboratory techniques.