Selected Publications

Academic Article

Year Title Altmetric
2019 Top-down mass spectrometry of intact phosphorylated β-casein: Correlation between the precursor charge state and internal fragmentsJournal of Mass Spectrometry.  54:527-539. 2019
2019 Detection of Lipid Mediators of Inflammation in the Human Tear Film 2019
2019 Lipidomic analysis of meibomian gland secretions from the tree shrew: Identification of candidate tear lipids critical for reducing evaporationChemistry and Physics of Lipids.  220:36-48. 2019
2019 Untargeted lipidomic analysis of human tears: A new approach for quantification of O-acyl-omega hydroxy fatty acids 2019
2018 Comparison of Collection Methods for the Measure of Human Meibum and Tear Film-Derived Lipids Using Mass SpectrometryCurrent Eye Research.  43:1244-1252. 2018
2018 Analysis of solute-protein interactions and solute-solute competition by zonal elution affinity chromatographyMethods.  146:3-11. 2018
2018 Comprehensive shotgun lipidomics of human meibomian gland secretions using MS/MSall with successive switching between acquisition polarity modesJournal of Lipid Research.  59:2223-2236. 2018
2017 Expression profiling of nonpolar lipids in meibum from patients with dry eye: A pilot studyInvestigative Ophthalmology and Visual Science.  58:2266-2274. 2017
2016 Compositional Analysis of Wax Esters in Human Meibomian Gland Secretions by Direct Infusion Electrospray Ionization Mass SpectrometryLipids.  51:1269-1287. 2016
2013 Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometryInvestigative Ophthalmology and Visual Science.  54:5730-5753. 2013
2012 A pseudo MS 3 approach for identification of disulfide-bonded proteins: Uncommon product ions and database searchJournal of The American Society for Mass Spectrometry.  23:225-243. 2012
2011 Author response: On the presence of (O-acyl)-omega-hydroxy fatty acids and their esters in human meibomian gland secretionsInvestigative Ophthalmology and Visual Science.  52:1894-1895. 2011
2010 Re-on the presence and role of polar lipids in meibumInvestigative Ophthalmology and Visual Science.  51:6910-6911. 2010
2010 Shotgun lipidomic analysis of human meibomian gland secretions with electrospray ionization tandem mass spectrometryInvestigative Ophthalmology and Visual Science.  51:6220-6231. 2010
2010 Top-down characterization of a native highly intralinked protein: Concurrent cleavages of disulfide and protein backbone bondsAnalytical Chemistry.  82:6079-6089. 2010
2009 Noncompetitive peak decay analysis of drug-protein dissociation by high-performance affinity chromatography 2009
2007 Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry 2007
2006 Quantitative studies of allosteric effects by biointeraction chromatography: Analysis of protein binding for low-solubility drugsAnalytical Chemistry.  78:2672-2683. 2006
2006 Chromatographic analysis of allosteric effects between ibuprofen and benzodiazepines on human serum albumin 2006
2004 Quantitative analysis of allosteric drug-protein binding by biointeraction chromatographyNature Biotechnology.  22:1445-1448. 2004
2004 Studies of phenytoin binding to human serum albumin by high-performance affinity chromatography 2004
2004 Characterization of drug interactions with soluble β-cyclodextrin by high-performance affinity chromatography 2004

Education And Training

  • Doctor of Philosophy in Chemistry, 2003
  • Master of Science in Chemistry, 1998
  • Bachelor of Science or Mathematics in Chemistry, 1993
  • Full Name

  • Jianzhong Chen