Wadiche, Jacques

Wadiche, Jacques
Associate Professor

Associate Professor (P), Neurobiology , Academic Joint Departments 2006 -
Associate Scientist (C), Civitan International Research Center , Academic Joint Departments 2006 -
Associate Scientist (C), Center for Glial Biology in Medicine , Academic Joint Departments 2006 -
Scientist (C), Comprehensive Neuroscience Center , General Clinical Research Center 2008 -
Scientist (C), Global Center for Craniofacial, Oral and Dental Disorders (GC-CODED) , School of Dentistry 2017 -
Associate Professor (S), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments 2018 -

Selected Publications

Academic Article

Year	Title	Altmetric
2019	NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum 2019
2019	The readily-releasable pool dynamically regulates multivesicular release 2019
2018	Constitutive and synaptic activation of GIRK channels differentiates mature and newborn dentate granule cells 2018
2017	Non-synaptic signaling from cerebellar climbing fibers modulates Golgi cell activity 2017
2017	Non-synaptic signaling from cerebellar climbing fibers modulates Golgi cell activity. 2017
2017	Adult-born neurons modify excitatory synaptic transmission to existing neurons 2017
2016	Low excitatory innervation balances high intrinsic excitability of immature dentate neurons 2016
2016	Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission 2016
2015	The ubiquitous nature of multivesicular release 2015
2015	New Neurons Don't Talk Back 2015
2014	Good housekeeping 2014
2014	Hilar mossy cells provide the first glutamatergic synapses to adult-born dentate granule cells 2014
2014	The contribution of extrasynaptic signaling to cerebellar information processing 2014
2013	Distinct determinants of sparse activation during granule cell maturation 2013
2013	Spillover-Mediated Feedforward Inhibition Functionally Segregates Interneuron Activity 2013
2013	GABA depolarization is required for experience-dependent synapse unsilencing in adult-born neurons 2013
2012	Neuronal glutamate transporters regulate glial excitatory transmission 2012
2011	Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche 2011
2011	Desynchronization of Multivesicular Release Enhances Purkinje Cell Output 2011
2007	Glutamate transporters: Confining runaway excitation by shaping synaptic transmission 2007
2006	Long-distance signaling via presynaptic glutamate transporters 2006
2006	Intrinsic kinetics determine the time course of neuronal synaptic transporter currents 2006
2005	Patterned expression of Purkinje cell glutamate transporters controls synaptic plasticity 2005
2004	Retroinhibition of presynaptic Ca2+ currents by endocannabinoids released via postsynaptic mGluR activation at a calyx synapse 2004
2001	Multivesicular release at climbing fiber-Purkinje cell synapses 2001
1998	Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel 1998
1995	Ion fluxes associated with excitatory amino acid transport 1995
1995	Kinetics of a human glutamate transporter 1995
1994	Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex 1994
1993	Molecular cloning, functional properties, and distribution of rat brain α7: A nicotinic cation channel highly permeable to calcium 1993

Principal Investigator On

AMPAR Function in Synaptic and Extrasynaptic Membranes awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2019 - 2024

Subcellular Localization of Glutamate Spillover on to Inhibitory Interneurons in the Cerebellar Cortex awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2018 - 2020

Timing of Neurotransmitter Release awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2014 - 2019

Extrasynaptic Signaling to Interneuron Networks awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2015 - 2017

Glutamate Spillover Transmission in the Cerebellar Cortex awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2014

Timing of Neurotransmitter Release awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2009 - 2014

Investigator On

Newborn Neurons In The Adult Hippocampal Network awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2019 - 2024

Inhibitory Neural Circuits in Dentate Function awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2018 - 2023

Newborn Neurons in the Adult Hippocampal Network awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2015 - 2019

Identification of Robust and Relevant Pre-Clinical Phenotypes for LRRK2 Therapeutics awarded by Fox (Michael J.) Foundation for Parkinson's Research 2015 - 2018

RII Track-2 FEC: Bridging Cognitive Science and Neuroscience Using Innovative Imaging Technologies awarded by Medical University of South Carolina 2015 - 2016

Training Program in the Neurobiology of Cognition and Cognitive Disorders awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2016

Mechanisms of Activity-Dependent Myelination in the Visual System awarded by National Eye Institute/NIH/DHHS 2015 - 2016

Newborn Neurons in the Adult Hippocampal Network awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2014 - 2015

Teaching Activities

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2019) 2019

GBSC729 - Cell Neurophysiology (Spring Term 2019) 2019

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2019) 2019

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2018) 2018

GBSC729 - Cell Neurophysiology (Spring Term 2018) 2018

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2018) 2018

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2017) 2017

GBSC729 - Cell Neurophysiology (Spring Term 2017) 2017

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2017) 2017

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2016) 2016

GBS746 - Special Topics (Spring Term 2016) 2016

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2016) 2016

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2015) 2015

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2015) 2015

GBS734 - Neuroscience Historical Lit JC (Fall Term 2014) 2014

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2014) 2014

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2014) 2014

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2013) 2013

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2013) 2013

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2012) 2012

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2012) 2012

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2011) 2011

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2011) 2011

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2010) 2010

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2010) 2010

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2009) 2009

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2009) 2009

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2008) 2008

NBL784 - Syn Transm & Ion Chan JC (Spring Term 2008) 2008

NBL784 - Syn Transm & Ion Chan JC (Fall Term 2007) 2007

Full Name

Jacques Wadiche

Wadiche, Jacques Associate Professor

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Publications