Journal of Molecular Biology

Structural Insights into the Mechanism of HIV-1 Tat Secretion from the Plasma Membrane.  435. 2023

Molecular Determinants of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly.  434. 2022

Nuclear Protein Condensates and Their Properties in Regulation of Gene Expression.  434. 2022

Structural Insights into the Mechanism of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly.  433. 2021

Corrigendum to “Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modified Kinase and GTP-binding Activities” [J. Mol. Biol. 412(1) (2011) 94–110] (Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities (2011) 412(1) (94–110), (S0022283611007984), (10.1016/j.jmb.2011.07.033)).  433. 2021

Structural Interaction of Apolipoprotein A-I Mimetic Peptide with Amyloid-β Generates Toxic Hetero-oligomers.  432:1020-1034. 2020

The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca²⁺/CaM.  431:1440-1459. 2019

Nanodisc-Forming Scaffold Protein Promoted Retardation of Amyloid-Beta Aggregation.  430:4230-4244. 2018

Polyphosphate Stabilizes Protein Unfolding Intermediates as Soluble Amyloid-like Oligomers.  430:4195-4208. 2018

Evidence for Amino Acid Sequence Differences among Proteins resembling the L-Chain Subunits of Immunoglobulins.  200:27-37. 2018

Derepression of SaPIbov1 Is Independent of φNM1 Type 2 dUTPase Activity and Is Inhibited by dUTP and dUMP.  429:1570-1580. 2017

Molecular Mechanism of DNA Topoisomerase I-Dependent rDNA Silencing: Sir2p Recruitment at Ribosomal Genes.  428:4905-4916. 2016

A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors.  428:2557-2568. 2016

A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila..  428:2446-2461. 2016

Follow the Yellow Brick Road: A Paradigm Shift in Virus Assembly.  428:416-418. 2016

The Type 2 dUTPase of Bacteriophage PdblNM1 Initiates Mobilization of Staphylococcus aureus Bovine Pathogenicity Island 1.  428:142-152. 2016

Protein quality control under oxidative stress conditions.  427:1549-1563. 2015

Restoration of NBD1 thermal stability is necessary and sufficient to correct Δf508 CFTR folding and assembly.  427:106-120. 2015

E. coli ClpA catalyzed polypeptide translocation is allosterically controlled by the protease ClpP.  425:2795-2812. 2013

Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription.  425:812-829. 2013

A human TOP2A core DNA binding X-ray structure reveals topoisomerase subunit dynamics and a potential mechanism for SUMO modulation of decatenation.  424:105-108. 2012

The effect of Aβ on IAPP aggregation in the presence of an isolated β-cell membrane.  421:348-363. 2012

Improved modeling of side-chain-base interactions and plasticity in protein-dna interface design.  419:255-274. 2012

Erratum: Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily (Journal of Molecular Biology (2012) 415:4 (741-758)).  416:725. 2012

Alternative relay and converter domains tune native muscle myosin isoform function in Drosophila..  416:543-557. 2012

Molecular structure and peptidoglycan recognition of mycobacterium tuberculosis ArfA (Rv0899).  416:208-220. 2012

Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: A member of the phospholipase D superfamily.  415:741-758. 2012

The crystal structure analysis of group B streptococcus sortase C1: A model for the "lid" movement upon substrate binding.  414:563-577. 2011

The staphylococcus aureus pathogenicity island 1 protein gp6 functions as an internal scaffold during capsid size determination.  412:710-722. 2011

Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities.  412:94-110. 2011

Structural basis for the function of Tim50 in the mitochondrial presequence translocase.  411:513-519. 2011

A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly.  410:641-652. 2011

New approaches for antiviral targeting of HIV assembly.  410:634-640. 2011

Activity of E. coli ClpA bound by nucleoside diphosphates and triphosphates.  409:333-347. 2011

A model for group B Streptococcus pilus type 1: The structure of a 35-kDa C-terminal fragment of the major pilin GBS80.  407:731-743. 2011

A conformational switch involved in maturation of staphylococcus aureus bacteriophage 80α capsids.  405:863-876. 2011

The NusA N-Terminal Domain Is Necessary and Sufficient for Enhancement of Transcriptional Pausing via Interaction with the RNA Exit Channel of RNA Polymerase.  401:708-725. 2010

Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability..  398:625-632. 2010

Crystal structure of P58(IPK) TPR fragment reveals the mechanism for its molecular chaperone activity in UPR.  397:1307-1315. 2010

Molecular mechanism of polypeptide translocation catalyzed by the Escherichia coli ClpA Protein Translocase.  399:665-679. 2010

Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head..  389:707-721. 2009

Transcriptional Activation of Human Matrix Metalloproteinase-9 Gene Expression by Multiple Co-activators.  383:945-956. 2008

Localization of the N-Terminus of Minor Coat Protein IIIa in the Adenovirus Capsid.  383:923-934. 2008

Structure of the Myristylated Human Immunodeficiency Virus Type 2 Matrix Protein and the Role of Phosphatidylinositol-(4,5)-Bisphosphate in Membrane Targeting.  382:434-447. 2008

Detection of Intermediates and Kinetic Control during Assembly of Bacteriophage P22 Procapsid.  381:1395-1406. 2008

Probing Conserved Helical Modules of Portal Complexes by Mass Spectrometry-based Hydrogen/Deuterium Exchange.  381:772-784. 2008

Capsid Size Determination by Staphylococcus aureus Pathogenicity Island SaPI1 Involves Specific Incorporation of SaPI1 Proteins into Procapsids.  380:465-475. 2008

Comprehensive Mapping of the C-Terminus of Flap Endonuclease-1 Reveals Distinct Interaction Sites for Five Proteins That Represent Different DNA Replication and Repair Pathways.  377:679-690. 2008

Still Looking for the Magic Spot: The Crystallographically Defined Binding Site for ppGpp on RNA Polymerase Is Unlikely to Be Responsible for rRNA Transcription Regulation.  377:551-564. 2008

Remodeling of the Human Papillomavirus Type 11 Replication Origin into Discrete Nucleoprotein Particles and Looped Structures by the E2 Protein.  375:1165-1177. 2008

Subunit Conformations and Assembly States of a DNA-translocating Motor: The Terminase of Bacteriophage P22.  374:817-836. 2007

Mutation of a Conserved Active Site Residue Converts Tyrosyl-DNA Phosphodiesterase I into a DNA Topoisomerase I-dependent Poison.  372:1070-1081. 2007

Cold-adaptation in Sea-water-borne Signal Proteins: Sequence and NMR Structure of the Pheromone En-6 from the Antarctic Ciliate Euplotes nobilii.  372:277-286. 2007

HIV-1 Protease Dimer Interface Mutations that Compensate for Viral Reverse Transcriptase Instability in Infectious Virions.  372:369-381. 2007

Structure of a Complex of Human Lactoferrin N-lobe with Pneumococcal Surface Protein A Provides Insight into Microbial Defense Mechanism.  370:701-713. 2007

Crystal Structure of Pyruvate Dehydrogenase Phosphatase 1 and its Functional Implications.  370:417-426. 2007

Crystal Structure of an Asymmetric Complex of Pyruvate Dehydrogenase Kinase 3 with Lipoyl Domain 2 and its Biological Implications.  370:407-416. 2007

Structure of a SUMO-binding-motif Mimic Bound to Smt3p-Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein-E2 Complex as a Platform for Selective Interactions within a SUMO Pathway.  369:619-630. 2007

Identification and Characterization of CMP-NeuAc:GalNAc-IgA1 α2,6-Sialyltransferase in IgA1-producing Cells.  369:69-78. 2007

NMR Structure and Functional Characterization of a Human Cancer-related Nucleoside Triphosphatase.  367:788-801. 2007

The Crystal Structure of C2a, the Catalytic Fragment of Classical Pathway C3 and C5 Convertase of Human Complement.  367:224-233. 2007

Molecular Dissection of Ø29 Scaffolding Protein Function in an in Vitro Assembly System.  366:1161-1173. 2007

Point Mutations in the HIV-1 Matrix Protein Turn Off the Myristyl Switch.  366:574-585. 2007

Analysis of Amino Acids in the β7-β8 Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase for their Role in Virus Replication.  365:1368-1378. 2007

Crystal Structure of the Translocation ATPase SecA from Thermus thermophilus Reveals a Parallel, Head-to-Head Dimer.  364:248-258. 2006

Crystal Structure of Yeast Mitochondrial Peripheral Membrane Protein Tim44p C-terminal Domain.  359:798-804. 2006

alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress..  358:635-645. 2006

DNA polymerase X from African swine fever virus: Quantitative analysis of the enzyme-ssDNA interactions and the functional structure of the complex.  356:121-141. 2006

Identification of elements essential for transcription in Brugia malayi promoters.  353:1-13. 2005

Energetics of DNA end binding by E. coli RecBC and RecBCD helicases indicate loop formation in the 3′-single-stranded DNA tail.  352:765-782. 2005

Identification of amino acid residues in the human immunodeficiency virus type-1 reverse transcriptase tryptophan-repeat motif that are required for subunit interaction using infectious virions.  349:673-684. 2005

Discrimination between defects in elongation fidelity and termination efficiency provides mechanistic insights into translational readthrough.  348:801-815. 2005

Domain study of bacteriophage P22 coat protein and characterization of the capsid lattice transformation by hydrogen/deuterium exchange.  347:935-948. 2005

The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40.  346:1005-1011. 2005

Double belt structure of discoidal high density lipoproteins: Molecular basis for size heterogeneity.  343:1293-1311. 2004

Structure of Mycobacterium tuberculosis FtsZ reveals unexpected, G protein-like conformational switches.  342:953-970. 2004

The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.  342:503-514. 2004

Effects of temperature and ATP on the kinetic mechanism and kinetic step-size for E. coli RecBCD helicase-catalyzed DNA unwinding.  339:751-771. 2004

Fluorescence stopped-flow studies of single turnover kinetics of E. coli RecBCD helicase-catalyzed DNA unwinding.  339:731-750. 2004

Erratum: Identification of Novel Interactions in HIV-1 Capsid Protein Assembly by High-resolution Mass Spectrometry (Journal of Molecular Biology (2003) 325 (759-772)).  334:1133. 2003

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.  334:733-749. 2003

Crystal structure of a lysine biosynthesis enzyme, LysX, from Thermus thermophilus HB8.  332:729-740. 2003

Insights into the catalytic mechanism of cofactor-independent phosphoglycerate mutase from X-ray crystallography, simulated dynamics and molecular modeling.  328:909-920. 2003

A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor.  328:131-146. 2003

Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.  325:759-772. 2003

Activation of striated muscle: Nearest-neighbor regulatory-unit and cross-bridge influence on myofilament kinetics.  322:1065-1088. 2002

Bacteriophage p22 portal vertex formation in vivo.  315:975-994. 2002

Crystal structure of E. coli Hsp100 ClpB nucleotide-binding domain 1 (NBD1) and mechanistic studies on ClpB ATPase activity..  318:1127-1137. 2002

DNA unwinding step-size of E. coli RecBCD helicase determined from single turnover chemical quenched-flow kinetic studies.  324:409-428. 2002

Molecular dynamics simulations on discoidal HDL particles suggest a mechanism for rotation in the apo A-I belt model.  324:703-721. 2002

Hydrogen-deuterium exchange as a probe of folding and assembly in viral capsids.  306:389-396. 2001

Design, characterization, and structure of a biologically active single-chain mutant of human IFN-γ.  299:169-179. 2000

Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.  297:1195-1202. 2000

Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy.  297:615-626. 2000

Identification of the C3b binding site in a recombinant vWF-A domain of complement factor B by surface-enhanced laser desorption-ionisation affinity mass spectrometry and homology modelling: Implications for the activity of factor B.  294:587-599. 1999

Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.  293:1107-1119. 1999

Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide.  292:361-373. 1999

An amphipathic α-helix at a membrane interface: A structural study using a novel X-ray diffraction method.  290:99-117. 1999

The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus phiX174..  288:595-608. 1999

The role of scaffolding proteins in the assembly of the small, single-stranded DNA virus φX174 1 1Edited by I. A. Wilson.  288:595-608. 1999

Cavity defects in the procapsid of bacteriophage P22 and the mechanism of capsid maturation.  287:527-538. 1999

Crystal structures of Phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue.  287:555-568. 1999

Crystal structure of ovine interferon-τ at 2.1 Å resolution.  286:151-162. 1999

Structures of native and complexed complement factor D: Implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.  282:1061-1081. 1998

A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: Crystal structures of an abzyme at 1.8 Å resolution.  281:501-511. 1998

Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.  281:285-299. 1998

A helical coat protein recognition domain of the bacteriophage P22 scaffolding protein.  281:81-94. 1998

Functional domains of bacteriophage P22 scaffolding protein.  281:69-79. 1998

The identification and characterization of microsatellites in the compact genome of the Japanese Pufferfish, Fugu rubripes: Perspectives in functional and comparative genomic analyses.  278:843-854. 1998

Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase.  269:494-504. 1997

Bacteriophage p22 scaffolding protein forms oligomers in solution.  268:655-665. 1997

Guanidinobenzoic acid inhibitors of influenza virus neuraminidase.  267:584-594. 1997

Assessment of protein fold predictions from sequence information: The predicted α/β doubly wound fold of the von Willebrand factor type a domain is similar to its crystal structure.  260:277-285. 1996

Three-dimensional structure of scaffolding-containing phage P22 procapsids by electron cryo-microscopy.  260:85-98. 1996

Regulation of codBA operon expression in Escherichia coli by UTP-dependent reiterative transcription and UTP-sensitive transcriptional start site switching..  254:552-565. 1995

The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.  251:334-345. 1995

The capsid size-determining protein Sid forms an external scaffold on phage P4 procapsids.  251:59-75. 1995

Rescue and replication signals of the adeno-associated virus 2 genome.  250:573-580. 1995

Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: Refinement at 1.45 Å and X-ray analysis of the three active site mutants.  249:360-375. 1995

Preliminary crystallographic study of Escherichia coli RuvC protein. An endonuclease specific for holliday junctions.  241:281-282. 1994

An escherichia coli RNA polymerase defective in transcription due to its overproduction of abortive initiation products.  236:72-80. 1994

Preliminary crystallographic studies on human complement pro-factor D.  235:1144-1146. 1994

Oxygen radical induced mutagenesis is DNA polymerase specific.  235:33-41. 1994

Structure of Human Factor D Complement System Protein at 2·0 Å Resolution.  235:695-708. 1994

Structure of human factor D: A complement system protein at 2.0 Å resolution.  235:695-708. 1994

Structural transitions during maturation of bacteriophage lambda capsids..  233:682-694. 1993

Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2′GMP.  230:979-996. 1993

Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus.  231:65-74. 1993

An accurate method for determining the helical repeat of DNA in solution reveals differences to the crystal structures of two B-DNA decamers.  228:322-326. 1992

Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.  224:1075-1085. 1992

Crystallization and preliminary X-ray investigation of factor D of human complement.  219:1-3. 1991

Purification, crystallization and preliminary crystallographic analysis of porcine aldose reductase.  218:695-698. 1991

Scaffolding protein regulates the polymerization of P22 coat subunits into icosahedral shells in vitro.  202:743-757. 1988

Alterations in DNA helix stability due to base modifications can be evaluated using denaturing gradient gel electrophoresis.  198:737-744. 1987

Regulation of α operon gene expression in Escherichia coli. A novel form of translational coupling.  196:333-345. 1987

Increased expression of ribosomal genes during inhibition of ribosome assembly in Escherichia coli.  184:23-30. 1985

Sequence and linkage of the goat ε^I and ε^II β-globin genes.  169:31-52. 1983

Oligomeric structure of a simian virus 40 T antigen in free form and bound to DNA.  148:347-353. 1981

Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2.  139:221-242. 1980

Interpretations of the effects of pH on the spectra of purple membrane.  135:595-609. 1979

Complex splicing patterns of RNAs from the early regions of adenovirus-2.  134:265-303. 1979

Electron microscopic characterization of DNAs of non-defective deletion mutants of bacteriophage Mu.  113:591-609. 1977

Sequence arrangements of the Escherichia coli chromosome and of putative insertion sequences, as revealed by electron microscopic heteroduplex studies.  113:611-621. 1977

Underwound loops in self-renatured DNA can be diagnostic of inverted duplications and translocated sequences.  113:579-589. 1977

A model for replication repair in mammalian cells.  101:417-425. 1976

Membrane proteins: Amino acid sequence and membrane penetration.  87:853-858. 1974

Electron microscope study of the structures of λdv DNAs.  86. 1974

Electron microscope mapping of the distribution of ribosomal genes of the Bacillus subtilis chromosome.  75. 1973

Electron microscope study of the structures of the Bacillus subtilis prophages, SPO2 and φ105.  75. 1973

Map of the partial sequence homology between DNA molecules of Bacillus subtilis bacteriophages SPO2 and φ105.  68. 1972

The sequence of gene product interaction in bacteriophage T4 tail core assembly.  58:685-692. 1971