Shock

Potential Immunotherapeutic Targets for Hypoxia Due to COVI-Flu.  54:438-450. 2020

The Association Between ABO Blood Type and Mortality Among Severely Injured Trauma Patients.  54:205-208. 2020

Impact of Glycemic Control on Risk of Mortality and Complications in Trauma Patients.  54:30-34. 2020

The Prognostic Value of Presepsin for Sepsis in Abdominal Surgery: A Prospective Study.  54:56-61. 2020

Temporal Dysregulation of the Angiopoietin-2/-1 Ratio After Trauma and Associations With Injury Characteristics and Outcomes. 2020

Plasma Angiopoietin-2/-1 Ratio is Elevated and Angiopoietin-2 Levels Correlate with Plasma Syndecan-1 Following Pediatric Trauma.  52:340-346. 2019

A Comparison of Outcomes of Trauma Patients With Ventilator-Associated Events by Diagnostic Criteria Set.  51:599-604. 2019

Part III: Minimum Quality Threshold in Preclinical Sepsis Studies (MQTiPSS) for Fluid Resuscitation and Antimicrobial Therapy Endpoints.  51:33-43. 2019

Premise for Standardized Sepsis Models.  51:4-9. 2019

Pulmonary Mechanics and Mortality in Mechanically Ventilated Patients Without Acute Respiratory Distress Syndrome.  49:311-316. 2018

Histone-Complexed DNA Fragments Levels are Associated with Coagulopathy, Endothelial Cell Damage, and Increased Mortality after Severe Pediatric Trauma.  49:44-52. 2018

Minimum quality threshold in pre-clinical sepsis studies (mqtipss): An international expert consensus initiative for improvement of animal modeling in sepsis.  50:377-380. 2018

Risk factors for the development of acute respiratory distress syndrome following hemorrhage.  50:258-264. 2018

A comparison of clinical characteristics and outcomes of ventilator-associated pneumonias among burn patients by diagnostic criteria set.  48:624-628. 2017

Earlier Endpoints are Required for Hemorrhagic Shock Trials Among Severely Injured Patients.  47:567-573. 2017

Hepatoprotective effects of corilagin following hemorrhagic shock are through Akt-dependent pathway.  47:346-351. 2017

Early coagulopathy is associated with increased incidence of ventilator-associated events among burn patients.  47:107-110. 2017

Previous Cryopreservation Alters the Natural History of the Red Blood Cell Storage Lesion.  46:89-95. 2016

The Role and Use of Estrogens Following Trauma.  46:4-11. 2016

What if i Don't Have Blood? Hextend is Superior to 3% Saline in an Experimental Model of Far Forward Resuscitation after Hemorrhage.  46:148-153. 2016

Early trauma-induced coagulopathy is associated with increased ventilator-associated pneumonia in spinal cord injury patients.  45:502-505. 2016

The glycocalyx and trauma: A review.  45:338-348. 2016

Hepatoprotective effect of casodex after trauma hemorrhage in a rodent model.  43:470-474. 2015

Expression of Concern.  43:620. 2015

The ERRor of our ways: Estrogen-related receptors are about energy, not hormones, and are potential new targets for trauma and shock.  44:3-15. 2015

Abandon the mouse research ship? Not just yet!.  41:463-475. 2014

Characterization of cardiac dysfunction in sepsis: An ongoing challenge.  41:12-24. 2014

Coagulopathy after severe pediatric trauma.  41:476-490. 2014

Macrophage-derived chemokine (CCL22) is a novel mediator of lung inflammation following hemorrhage and resuscitation.  42:525-531. 2014

The august krogh principle: Seeking unity in diversity: Reply.  42:480-481. 2014

Impact of high ratios of plasmaytoyred cell concentrate on the incidence of acute respiratory distress syndrome in uk transfused combat casualties.  40:15-20. 2013

Early coagulopathy is an independent predictor of mortality in children after severe trauma.  39:421-426. 2013

Activation of the heat shock response attenuates the interleukin 1β-mediated inhibition of the amiloride-sensitive alveolar epithelial ion transport.  39:189-196. 2013

Tranexamic acid and trauma: Current status and knowledge gaps with recommended research priorities.  39:121-126. 2013

Hepatic gene expression patterns following trauma-hemorrhage: Effect of posttreatment with estrogen.  39:77-82. 2013

Resuscitative endovascular balloon occlusion of the aorta: A gap analysis of severely injured UK Combat casualties.  41:388-393. 2013

Microvascular response to red blood cell transfusion in trauma patients.  37:276-281. 2012

Hypoxia-induced alteration of mitochondrial genes in cardiomyocytes: Role of Bnip3 and Pdk1.  34:169-175. 2010

Mechanism of the anti-inflammatory effect of 17β-estradiol on brain following trauma-hemorrhage.  33:43-48. 2010

Increase in activated protein C mediates acute traumatic coagulopathy in mice.  32:659-665. 2009

Erratum: Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels (Shock (2008) 30 (372-378)).  32:563. 2009

Estrogen suppresses cardiac IL-6 after trauma-hemorrhage via a hypoxia-inducible factor 1α-mediated pathway.  31:354-358. 2009

The role of estrogen and receptor agonists in maintaining organ function after trauma-hemorrhage.  31:227-237. 2009

MECHANISM OF CARDIOPROTECTION BY ESTROGEN (E2) FOLLOWING TRAUMA-HEMORRHAGE (T-H): UPREGULATION OF CARDIAC O-GLYCOSALATION.  31:89-89. 2009

Reproducibility of an animal model simulating complex combat-related injury in a multiple-institution format.  31:87-96. 2009

Resuscitation with the hemoglobin-based oxygen carrier, hboc-201, in a swine model of severe uncontrolled hemorrhage and traumatic brain injury.  31:64-79. 2009

Systematic analysis of the salutary effect of estrogen on cardiac performance after trauma-hemorrhage.  30:585-589. 2008

Mechanism of estrogen-mediated improvement in cardiac function after trauma-hemorrhage: p38-dependent normalization of cardiac Akt phosphorylation and glycogen levels.  30:372-378. 2008

Hexosamine biosynthesis and protein O-glycosylation: The first line of defense against stress, ischemia, and trauma.  29:431-440. 2008

Acute alcohol intoxication potentiates neutrophil-mediated intestinal tissue damage after burn injury.  29:377-383. 2008

Effect of 17β-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma.  29:362-371. 2008

Mechanism of estradiol-mediated cardio-protection following trauma-hemorrhage: Upregulation of cardiac O-glycosylation/phosphorylation.  29:21-22. 2008

Keratinocyte-derived chemokine plays a critical role in the induction of systemic inflammation and tissue damage after trauma-hemorrhage.  28:576-581. 2007

Glucosamine administration improves survival rate after severe hemorrhagic shock combined with trauma in rats.  28:345-352. 2007

Regulation of the postburn wound inflammatory response by γδ T-cells.  28:278-283. 2007

Role of the alternative pathway in the early complement activation following major trauma.  28:29-34. 2007

Estrogen improves hepatic function following trauma-hemorrhage: Increased estrogen receptor-alpha expression and antioxidant activity.  27:59-59. 2007

Mechanism of the salutary effects of 17 beta-estradiol on cardiac function following trauma-hemorrhage: Inhibition of cardiomyocyte L-type calcium current (ICa-L).  27:60-60. 2007

Resuscitation from hemorrhagic shock with HBOC-201 in the setting of traumatic brain injury.  27:652-656. 2007

The protective effects of PUGNAc on cardiac function after trauma-hemorrhage are mediated via increased protein O-GlcNAc levels.  27:402-408. 2007

Influence of sex and age on mods and cytokines after multiple injuries.  27:151-156. 2007

Bovine polymerized hemoglobin versus hextend resuscitation in a swine model of severe controlled hemorrhagic shock with delay to definitive care.  26:302-310. 2006

Glucosamine administration during resuscitation improves organ function after trauma hemorrhage.  25:600-607. 2006

Left ventricular diastolic filling characteristics are not impaired but systolic performance was augmented in the early hours of experimental endotoxemia in humans.  25:338-343. 2006

Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage.  25:50-55. 2006

Cecal ligation and puncture.  24:52-57. 2005

Gender differences in acute response to trauma-hemorrhage.  24:101-106. 2005

Dehydroepiandrosterone modulates toll-like receptor expression on splenic macrophages of mice after severe polymicrobial sepsis.  24:364-369. 2005

Endothelial dysfunction in trauma patients: A preliminary communication.  24:210-213. 2005

Genetic variability in the immune-inflammatory response after major burn injury.  23:123-128. 2005

The role of the mitochondrion in trauma and shock.  22:395-402. 2004

Glucosamine provides protection from ischemia/reperfusion injury and calcium overload in isolated hearts and leads to an increase in O-linked glycosylation.  21:58-58. 2004

Age-related gender differential in outcome after blunt or penetrating trauma..  19:28-32. 2003

Differential fluid regulation during and after soft tissue trauma and hemorrhagic shock in males and proestrus females..  20:144-148. 2003

Regulation of macrophage IL-10 production postinjury via beta2 integrin signaling and the P38 MAP kinase pathway..  20:529-535. 2003

Differential alterations in cardiovascular responses during the progression of polymicrobial sepsis in the mouse.  17:55-60. 2002

Gender differences in mortality following burn injury.  18:311-315. 2002

Scientific priorities and strategic planning for resuscitation research and life saving therapy following traumatic injury: Report of the PULSE Trauma Work Group.  17:165-168. 2002

Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis.  16:479-483. 2001

Evolution of an immune suppressive macrophage phenotype as a product of p38 MAPK activation in polymicrobial sepsis.  15:42-48. 2001

Strategies to improve myocardial protection during extracorporeal circulation.  16:20-23. 2001

Androgen and estrogen receptors in splenic T lymphocytes: Effects of flutamide and trauma-hemorrhage.  14:465-470. 2000

Does burn wound excision after thermal injury attenuate subsequent macrophage hyperactivity and immunosuppression?.  14:623-628. 2000

Effect of gender and sex hormones on immune responses following shock.  14:81-90. 2000

Reduction of vancomycin-resistant enterococcal infections by limitation of broad-spectrum cephalosporin use in a trauma and burn intensive care unit.  14:259-264. 2000

The aromatase inhibitor, 4-hydroxyandrostenedione, restores immune responses following trauma-hemorrhage in males and decreases mortality from subsequent sepsis.  14:347-353. 2000

Upregulation of inducible nitric oxide synthase and nitric oxide occurs later than the onset of the hyperdynamic response during sepsis.  13:325-329. 2000

Reply: Letters to the editor.  11:73-74. 1999

Does fas ligand or endotoxin contribute to thymic apoptosis during polymicrobial sepsis?.  11:211-217. 1999

Gender dimorphism in trauma-hemorrhage-induced thymocyte apoptosis.  12:316-322. 1999

Cardiac contractility and structure are not significantly compromised even during the late, hypodynamic stage of sepsis.  9:352-358. 1998

Trauma-hemorrhage activates signal transduction pathways in mouse splenic T cells.  9:443-450. 1998

Up-regulation of a novel potent vasodilatory peptide adrenomedullin during polymicrobial sepsis.  10:118-122. 1998

Impaired enterocyte triglyceride synthesis after trauma-hemorrhage and resuscitation..  8:33-39. 1997

Intestinal alkaline phosphatase: role in the depressed gut lipid transport after trauma-hemorrhagic shock..  8:40-44. 1997

Flutamide: A novel agent for restoring the depressed cell-mediated immunity following soft-tissue trauma and hemorrhagic shock.  8:242-248. 1997

A novel nonanticoagulant heparin prevents vascular endothelial cell dysfunction during hyperdynamic sepsis.  6:46-51. 1996

Administration of a matrix metalloproteinase inhibitor after hemorrhage improves cardiovascular and hepatocellular function.  6:377-382. 1996

Immune dysfunction in murine polymicrobial sepsis: Mediators, macrophages, lymphocytes and apoptosis.  6. 1996

Trauma-induced suppression of antigen presentation and expression of major histocompatibility class II antigen complex in leukocytes.  5:79-90. 1996

Hepatocellular dysfunction occurs earlier than the onset of hyperdynamic circulation during sepsis.  3:21-26. 1995

Sustained elevation in circulating catecholamine levels during polymicrobial sepsis.  4:269-273. 1995

The gut: A cytokine-generating organ in systemic inflammation?.  4:193-199. 1995

The induction of accelerated thymic programmed cell death during polymicrobial sepsis: Control by corticosteroids but not tumor necrosis factor.  3:259-267. 1995

Trauma-hemorrhage causes prolonged depression in cellular immunity.  4:149-153. 1995

Tumor necrosis factor-α administration increases kupffer cell cyclic adenosine monophosphate levels.  4:351-355. 1995

Aggressive fluid resuscitation following intestinal ischemia-reperfusion in immature rats prevents metabolic derangements and down regulates interleukin-6 release.  1:381-387. 1994

Differential alterations in cyclic nucleotide levels in kupffer cells and hepatocytes following trauma-hemorrhage and resuscitation.  1:438-442. 1994

Editorial.  1:1-2. 1994

Effects of cholinergic blockade on hemodynamic disturbances and intestinal lesions in endotoxic shockin newborn piglets.  2:98-105. 1994

Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock.  1:141-146. 1994

Hemorrhage induces a reduction in the capacity of macrophages to mobilize intracellular calcium secondary to formyl-methionyl-leucyl-phenylalanine stimulation: Association with alterations in cell surface Fc receptor expression and increased prostaglandin release.  1:228-235. 1994

Role of kupffer cells in interleukin-6 release following trauma-hemorrhage and resuscitation.  1:43-47. 1994