Publication Venue For
Discovery of novel inhibitors of ribosome biogenesis by innovative high throughput screening strategies.
Human C-reactive protein impedes entry of leptin into the CNS and attenuates its physiological actions in the CNS.
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
The sodium chloride cotransporter (NCC) and epithelial sodium channel (ENaC) associate.
Erratum: KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity (Biochemical Journal (2015) 469 (347-355)).
Escherichia coli ClpB is a non-processive polypeptide translocase.
KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity.
Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F.
Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria.
Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice.
Erratum: Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload (Biochemical Journal (2013) 455 (157-167)).
Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload.
Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts.
The type III TGFβ receptor regulates filopodia formation via a Cdc42-mediated IRSp53-N-WASP interaction in epithelial cells.
Erythrocyte storage increases rates of NO and nitrite scavenging: Implications for transfusion-related toxicity.
The RNA-binding protein CUG-BP1 increases survivin expression in oesophageal cancer cells through enhanced mRNA stability.
SP-1 regulation of MMP-9 expression requires Ser586in the PEST domain.
DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.
Proteoglycans of uterine fibroids and keloid scars: Similarity in their proteoglycan composition.
Cell signalling by reactive lipid species: New concepts and molecular mechanisms.
Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling.
Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator.
Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
The RNA-binding protein HuR stabilizes survivin mRNA in human oesophageal epithelial cells.
PPARγ co-activator-1α co-activates steroidogenic factor 1 to stimulate the synthesis of luteinizing hormone and aldosterone..
Prevention of diabetic nephropathy in Ins2+/-AkitaJ mice by the mitochondria-targeted therapy MitoQ.
Modulation of mammary cancer cell migration by 15-deoxy-Δ 12,14-prostaglandin J2: Implications for anti-metastatic therapy.
Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor.
Mitochondrial targeting of the electrophilic lipid 15-deoxy-Δ12,14- prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms.
The immunoproteasome, the 20S proteasome, and the PA28aß proteasome regulator are oxidative stress-adaptive proteolytic complexes..
Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal.
Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction.
Human haem oxygenase-1 induction by nitro-linoleic acid is mediated by cAMP, AP-1 and E-box response element interactions.
The permissive role of mitochondria in the induction of haem oxygenase-1 in endothelial cells.
High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.
Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.
Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling.
Accumulation of 15-deoxy-Δ12,14-prostaglandin J 2 adduct formation with Keap1 over time: Effects on potency for intracellular antioxidant defence induction.
Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change.
Enhanced cell-surface stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones.
EmbR2, a structural homologue of EmbR, inhibits the Mycobacterium tuberculosis kinase/substrate pair PknH/EmbR.
S-nitrosation and thiol switching in the mitochondrion: a new paradigm for cardioprotection in ischaemic preconditioning..
Evidence for oxygen as the master regulator of the responsiveness of soluble guanylate cyclase and cytochrome c oxidase to nitric oxide..
Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids.
Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex.
NABP1, a novel RORγ-regulated gene encoding a single-stranded nucleic-acid-binding protein.
Induction of the permeability transition and cytochrome c release by 15-deoxy-Δ12,14-prostaglandin J2 in mitochondria.
Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors.
Structure-based mutagenesis studies of the peptide substrate binding fragment of type I heat-shock protein 40.
Development of a chimaeric receptor approach to study signalling by tumour necrosis factor receptor family members.
Upstream stimulatory factors, USF1 and USF2, bind to the human haem oxygenase-1 proximal promoter in vivo and regulate its transcription.
Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes.
Mechanisms of the interaction of nitroxyl with mitochondria.
Cellular mechanisms of redox cell signalling: Role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products.
Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities.
Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities..
Accelerated ubiquitination and proteasome degradation of a genetic variant of inducible nitric oxide synthase.
Haem oxygenase 1 gene induction by glucose deprivation is mediated by reactive oxygen species via the mitochondrial electron-transport chain.
Phosphatidylethanolamine N-methyltransferase (PEMT) knockout mice have hepatic steatosis and abnormal hepatic choline metabolite concentrations despite ingesting a recommended dietary intake of choline.
CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain.
Induction of glutathione synthesis by oxidized low-density lipoprotein and 1-palmitoyl-2-arachidonyl phosphatidylcholine: Protection against quinone-mediated oxidative stress.
Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate.
Direct interactions between molecular chaperones heat-shock protein (Hsp) 70 and Hsp40: Yeast Hsp70 Ssa1 binds the extreme C-terminal region of yeast Hsp40 Sis1.
Overexpression of matrix metalloproteinase-2 mediates phenotypic transformation of lens epithelial cells.
Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells.
Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1.
Human Sug1/p45 is involved in the proteasome-dependent degradation of Sp1.
Calexcitin interaction with neuronal ryanodine receptors.
Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells.
Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.
Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin.
Reduction of Cu(II) by lipid hydroperoxides: Implications for the copper-dependent oxidation of low-density lipoprotein.
The human cardiac muscle ryanodine receptor-calcium release channel: Identification, primary structure and topological analysis.
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose.
Demonstration of specific insulin binding to cytosolic proteins in H35 hepatoma cells, rat liver and skeletal muscle..
306 ( Pt 1):21-28.
Cofactor role for 10-formyldihydrofolic acid.
Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation.
Inhibition of cytochrome c oxidase in turnover by nitric oxide: Mechanism and implications for control of respiration.
Pro-oxidant effects of cross-linked haemoglobins explored using liposome and cytochrome c oxidase vesicle model membranes.
Differences in methotrexate and 7-hydroxymethotrexate inhibition of folate-dependent enzymes of purine nucleotide biosynthesis.
Interactions of peroxynitrite with human plasma and its constituents: Oxidative damage and antioxidant depletion.
An insulin receptor peptide (1135-1156) stimulates guanosine 5'[γ-thio]triphosphate binding to the 67 kDa G-protein associated with the insulin receptor.
Inhibition of glutathione synthesis increases the toxicity of oxidized low-density lipoprotein to human monocytes and macrophages.
Inhibition of folate-dependent enzymes by non-steroidal anti-inflammatory drugs.
Pro-oxidant effects of lipoxygenase-derived peroxides on the copper-initiated oxidation of low-density lipoprotein.
Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide.
5-Lipoxygenase is not essential in macrophage-mediated oxidation of low-density lipoprotein.
Identification of bile acid-CoA:amino acid N-acyltransferase in rat kidney.
Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart.
Treatment of macrophages with oxidized low-density lipoprotein increases their intracellular glutathione content.
Detection of inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase by thioinosinic acid and azathioprine by a new colorimetric assay.
Solubilization and separation of inositol 1,3,4,5-tetrakisphosphate- and inositol 1,4,5-trisphosphate-binding proteins and metabolizing enzymes in rat brain.
Effect of 1-amino-oxy-3-aminopropane on polyamine metabolism and growth of L1210 cells.
A proton gradient, not a sodium gradient, is the driving force for active transport of lactate in rabbit intestinal brush-border membrane vesicles.
Effect of inhibitors of S-adenosylmethionine decarboxylase on the contents of ornithine decarboxylase and S-adenosylmethionine decarboxylase in L1210 cells.
Evidence for histidyl and carboxy groups at the active site of the human placental Na+-H+ exchanger..
Purification, characterization and proteinase-inhibitory activity of a Clara-cell secretory protein from the pulmonary extracellular lining of rabbits..
Reaction of unsaturated uronic acid residues with mercuric salts. Cleavage of the hyaluronic acid disaccharide 2-acetamido-2-deoxy-3-O-(beta-D-gluco-4-enepyranosyluronic acid)-D-glucose..
Synthesis of mucous glycoproteins by rabbit tracheal cells in vitro. Modulation by substratum, retinoids and cyclic AMP.
Binding of peptides that are specified by complementary RNAs.
Incorporation of [35S]sulphate into glycosaminoglycans by mineralized tissues in vivo.
Isolation and partial characterization of proteoglycans from rat incisors..
Metabolism of rat bone proteoglycans in vivo.
A method for the preparation of low-pH dodecyl sulphate/polyacrylamide-gradient gels..
Protein phosphorylation in human peripheral blood lymphocytes. Phosphorylation of endogenous plasma membrane and cytoplasmic proteins.
Protein phosphorylation in human peripheral blood lymphocytes. Subcellular distribution and partial characterization of adenosine 3':5'-cyclic monophosphate-dependent protein kinase.
The role of tubular reabsorption in the renal excretion of bile acids.