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Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology
. 295:17935-17949.
2020
A cell non-autonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism.
2020
Defining the divergent enzymatic properties of RNA polymerases I and II.
. 296:100051.
2020
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.
. 296:100034.
2020
Cadmium-mediated lung injury is exacerbated by the persistence of classically activated macrophages
. 295:15754-15766.
2020
Defining the divergent enzymatic properties of RNA polymerases I and II.
2020
Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells.
2020
Modulation of glycosyltransferase ST6Gal-I in gastric cancer-derived organoids disrupts homeostatic epithelial cell turnover
. 295:14153-14163.
2020
The GTPase Rab27b regulates the release, autophagic clearance, and toxicity of alpha-synuclein
. 295.
2020
The influenza NS1 protein modulates RIG-I activation via a strain-specific direct interaction with the second CARD of RIG-I
. 295:1153-1164.
2020
14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation
. 295:1754-1766.
2020
Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I
. 295:1288-1299.
2020
Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I
. 295:1288-1299.
2020
First characterization of glucose flux through the hexosamine biosynthesis pathway (HBP) in ex vivo mouse heart
. 295:2018-2033.
2020
Pulmonary surfactant lipids inhibit infections with the pandemic H1N1 influenza virus in several animal models
. 295:1704-1715.
2020
Structural and biophysical characterizations of HIV-1 matrix trimer binding to lipid nanodiscs shed light on virus assembly
. 294:18600-18612.
2019
Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands
. 294:17060-17074.
2019
Relative stabilities of wild-type and mutant glial fibrillary acidic protein in patients with Alexander disease
. 294:15604-15612.
2019
Distinct Fcα receptor N-glycans modulate the binding affinity to immunoglobulin A (IgA) antibodies
. 294:13995-14008.
2019
LIM-domain transcription complexes interact with ring-finger ubiquitin ligases and thereby impact islet-cell function
. 294:11728-11740.
2019
Hypoxia induces cancer cell-specific chromatin interactions and increases MALAT1 expression in breast cancer cells.
. 294:11213-11224.
2019
Correction: Triptolide-induced cell death in pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1 (Journal of Biological Chemistry (2013) 288 (33927-33938) DOI: 10.1074/jbc.M113.500983)
. 294:10739.
2019
Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice
. 294:10392-10406.
2019
Mitochondrial localization, import, and mitochondrial function of the androgen receptor
. 294:6621-6634.
2019
Correction: The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-related kinase (ERK)/NRF2 signaling pathway and cytokine release (Journal of Biological Chemistry (2012) 287:40 (33720-33732) DOI:10.1074/jbc.M112.385542)
. 294:4725-4727.
2019
Correction: Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C ?-mediated zona occludens-1 phosphorylation at threonine 770/772 (Journal of Biological Chemistry (2014) 289 (3148-3163) DPO: 10.1074/jbc.M113.528190)
. 294:3311.
2019
The tuberculosis necrotizing toxin is an NAD and NADP glycohydrolase with distinct enzymatic properties
. 294:3024-3036.
2019
Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex
. 294:838-851.
2019
Retraction: Down-regulated peroxisome proliferator-activated receptor γ(PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD) (Journal of Biological Chemistry (2014) 289 (6383–6393) DOI: 10.1074/jbc.M113.536805)
. 294:69.
2019
Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly
. 293:18828-18840.
2018
The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P
2
-binding site that targets Gag to the cell periphery
. 293:18841-18853.
2018
Complement 1q-like-3 protein inhibits insulin secretion from pancreatic -cells via the cell adhesion G protein– coupled receptor BAI3
. 293:18086-18098.
2018
Ligand binding to a remote site thermodynamically corrects the F508del mutation in the human cystic fibrosis transmembrane conductance regulator
. 293:17685-17704.
2018
CRISPR-delivery particles targeting nuclear receptor–interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure
. 293:17291-17305.
2018
Human interferon- and interferon- exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R
. 293:16057-16068.
2018
IL-1R signaling promotes STAT3 and NF-B factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription
. 293:15790-15800.
2018
Structural analyses reveal the mechanism of inhibition of influenza virus NS1 by two antiviral compounds
. 293:14659-14668.
2018
Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice
. 293:6996-7007.
2018
The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1 signaling
. 293:5659-5667.
2018
ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
. 293:1610-1622.
2018
C/EBPα transcription factor is regulated by the RANK cytoplasmic 535IVVY538 motif and stimulates osteoclastogenesis more strongly than c-Fos.
. 293:1480-1492.
2018
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation
. 293:1218-1228.
2018
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.
. 293:1218-1228.
2018
ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage
. 293:984-994.
2018
The microRNA-23a cluster regulates the developmental HoxA cluster function during osteoblast differentiation
. 293:17646-17660.
2018
A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.
. 292:20808-20817.
2017
Epigenetic modification of miR-663 controls mitochondriatonucleus retrograde signaling and tumor progression
. 292:20694-20706.
2017
Constitutive role of the Fanconi anemia D2 gene in the replication stress response.
. 292:20184-20195.
2017
ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα
. 292:18924-18936.
2017
Hu antigen R (HuR) multimerization contributes to glioma disease progression
. 292:16999-17010.
2017
Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations
. 292:14147-14164.
2017
The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand
. 292:10390-10397.
2017
The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis
. 292:5884-5897.
2017
The glycosyltransferase ST6Gal-I protects tumor cells against serum growth factor withdrawal by enhancing survival signaling and proliferative potential
. 292:4663-4673.
2017
NADPH Oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway
. 292:3029-3038.
2017
The interplay between calmodulin and membrane interactions with the pleckstrin homology domain of akt
. 292:251-263.
2017
Engineering and dissecting the glycosylation pathway of a streptococcal serine-rich repeat adhesin
. 291:27354-27363.
2016
Altering the proteoglycan state of transforming growth factor β type III receptor (TβRIII)/betaglycan modulates canonical Wnt/β-catenin signaling
. 291:25716-25728.
2016
Small molecule inhibition of the ubiquitin-specific protease USP2 accelerates cyclin D1 degradation and leads to cell cycle arrest in colorectal cancer and mantle cell lymphoma models
. 291:24628-24640.
2016
Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells
. 291:24188-24199.
2016
Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA
2
β Group VIA phospholipase a
2
. 291:23268-23281.
2016
New helical binding domain mediates a glycosyltransferase activity of a bifunctional protein
. 291:22106-22117.
2016
Human argonaute 2 is tethered to ribosomal RNA through MicroRNA interactions
. 291:17919-17928.
2016
CCAAT/enhancer-binding protein α (C/EBPα) is important for osteoclast differentiation and activity
. 291:16390-16403.
2016
Attenuation of PKR-like ER Kinase (PERK) signaling selectively controls endoplasmic reticulum stress-induced inflammation without compromising immunological responses
. 291:15830-15840.
2016
Characterization of the interactions between calmodulin and death receptor 5 in triple-negative and estrogen receptor-positive breast cancer cells: An integrated experimental and computational study
. 291:12862-12870.
2016
The tumor-suppressive small GTPase DiRas1 binds the noncanonical guanine nucleotide exchange factor SmgGDS and antagonizes SmgGDS interactions with oncogenic small GTPases.
. 291:10948-10948.
2016
Cytokines regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via distinct mechanisms and pathways
. 291:8428-8439.
2016
The B3 subunit of the cone cyclic nucleotide-gated channel regulates the light responses of cones and contributes to the channel structural flexibility
. 291:8721-8734.
2016
Dual Oxidase 2 (Duox2) Regulates Pannexin 1-mediated ATP Release in Primary Human Airway Epithelial Cells via Changes in Intracellular pH and Not H
2
O
2
Production
. 291:6423-6432.
2016
Interaction between a domain of the negative regulator of the ras-ERK pathway, SPRED1 protein, and the GTPase-activating protein-related domain of neurofibromin is implicated in legius syndrome and neurofibromatosis type 1
. 291:3124-3134.
2016
The transcription factor THO promotes transcription initiation and elongation by RNA Polymerase I
. 291:3010-3018.
2016
Channel gating regulation by the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop
. 291:1854-1865.
2016
Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions
. 291:1652-1663.
2016
The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II
. 291:1763-1773.
2016
Cytokine activation by antibody fragments targeted to cytokine-receptor signaling complexes
. 291:447-461.
2016
Structural plasticity of the protein plug that traps newly packaged genomes in podoviridae virions
. 291:215-226.
2016
E2F1 transcription factor regulates O-linked N-acetylglucosamine (O-GlcNAc) transferase and O-glcnacase expression
. 290:31013-31024.
2015
IL-1R/TLR2 through MyD88 divergently modulates osteoclastogenesis through regulation of nuclear factor of activated T cells c1 (NFATc1) and B lymphocyte-induced maturation protein-1 (Blimp1)
. 290:30163-30174.
2015
A Failure to Communicate
. 290:29270-29280.
2015
Poly(ADP-ribosyl)ation of FOXP3 Protein Mediated by PARP-1 Protein regulates the function of regulatory t cells
. 290:28675-28682.
2015
Structural and biophysical characterization of the interactions between calmodulin and the pleckstrin homology domain of Akt
. 290:27403-27413.
2015
Erratum: Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units (The Journal of Biological Chemistry (2013) 288 (25976-25985))
. 290:26474-26475.
2015
Airway surface dehydration by transforming growth factor β (TGF-β) in cystic fibrosis is due to decreased function of a voltage-dependent potassium channel and can be rescued by the drug pirfenidone
. 290:25710-25716.
2015
Metabolic reprogramming is required for myofibroblast contractility and differentiation
. 290:25427-25438.
2015
Genome-wide Mechanosensitive MicroRNA (MechanomiR) Screen Uncovers Dysregulation of Their Regulatory Networks in the mdm Mouse Model of Muscular Dystrophy.
. 290:24986-25011.
2015
The IVVY motif and tumor necrosis factor receptor-associated factor (TRAF) sites in the cytoplasmic domain of the receptor activator of nuclear factor κB (RANK) cooperate to induce osteoclastogenesis
. 290:23738-23750.
2015
Regulation of ergothioneine biosynthesis and its effect on Mycobacterium tuberculosis growth and infectivity
. 290:23064-23076.
2015
Shed syndecan-1 translocates to the nucleus of cells delivering growth factors and inhibiting histone acetylation: A novel mechanism of tumor-host cross-talk
. 290:941-949.
2015
Monocyte chemotactic protein-induced protein 1 and 4 form a complex but act independently in regulation of interleukin-6 mRNA degradation
. 290:20782-20792.
2015
Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration
. 290:19433-19444.
2015
Regulation of ERK kinase by MEK1 kinase inhibition in the brain
. 290:16319-16329.
2015
Endoglin regulation of Smad2 function mediates beclin1 expression and endothelial autophagy
. 290:14884-14892.
2015
Heterotrimeric Kinesin-2 (KIF3) mediates transition zone and axoneme formation of mouse photoreceptors
. 290:12765-12778.
2015
DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin
. 290:12068-12078.
2015
Group VIA phospholipase a
2
(iPLA
2
β) modulates Bcl-x 5′-splice site selection and suppresses anti-apoptotic Bcl-x(L) in β-cells
. 290:11021-11031.
2015
Transcriptional activity of the islet β cell factor Pdx1 Is augmented by lysine methylation catalyzed by the methyltransferase Set7/9
. 290:9812-9822.
2015
Centrobin-mediated regulation of the centrosomal protein 4.1-associated protein (CPAP) level limits centriole length during elongation stage
. 290:6890-6902.
2015
Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage
. 290:6203-6214.
2015
The monocarboxylate transporter 4 is required for glycolytic reprogramming and inflammatory response in macrophages
. 290:46-55.
2015
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell
. 289:36275-36283.
2014
Modulation of the mevalonate pathway by AKT regulates macrophage survival and development of pulmonary fibrosis
. 289:36204-36219.
2014
Protein O-GlcNAcylation and cardiovascular (patho)physiology
. 289:34449-34456.
2014
3 Asbestos-induced disruption of calcium homeostasis induces endoplasmic reticulum stress in macrophages
. 289:33391-33403.
2014
The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage
. 289:32883-32894.
2014
Unique functional and structural properties of the LRRK2 protein ATP-binding pocket
. 289:32937-32951.
2014
Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: Implications for amyotrophic lateral sclerosis
. 289:31792-31804.
2014
Gli1 protein regulates the S-phase checkpoint in tumor cells via bid protein, and its inhibition sensitizes to DNA Topoisomerase 1 inhibitors
. 289:31513-31525.
2014
An electrostatic interaction at the tetrahelix bundle promotes phosphorylation-dependent cystic fibrosis transmembrane conductance regulator (CFTR) channel opening
. 289:30364-30378.
2014
Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscle
. 289:29397-29405.
2014
Src-mediated post-translational regulation of endoglin stability and function is critical for angiogenesis
. 289:25486-25496.
2014
The calcium-induced conformation and glycosylation of scavenger-rich cysteine repeat (SRCR) domains of glycoprotein 340 influence the high affinity interaction with antigen I/II homologs
. 289:21877-21887.
2014
Structure of a novel O-linked N-acetyl-D-glucosamine (O-GlcNAc) transferase, GtfA, reveals insights into the glycosylation of pneumococcal serine-rich repeat adhesins
. 289:20898-20907.
2014
Co-activation of nuclear factor-κB and myocardin/serum response factor conveys the hypertrophy signal of high insulin levels in cardiac myoblasts
. 289:19585-19598.
2014
Negative regulation of NADPH oxidase 4 by Hydrogen peroxide-inducible clone 5 (Hic-5) protein
. 289:18270-18278.
2014
Mapping Interactions between Myosin Relay and Converter Domains That Power Muscle Function
. 289:12779-12790.
2014
O-GlcNAc transferase is critical for transducin-like enhancer of split (TLE)-mediated repression of canonicalwntsignaling
. 289:12168-12176.
2014
Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2
. 289:11807-11815.
2014
Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells
. 289:10466-10475.
2014
Hypoxic induction of vascular endothelial growth factor (VEGF) and angiogenesis in muscle by truncated peroxisome proliferator-activated receptor γ coactivator (PGC)-1α
. 289:8810-8817.
2014
Solution structure of calmodulin bound to the binding domain of the HIV-1 matrix protein
. 289:8697-8705.
2014
Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding.
. 289:7948-7961.
2014
Down-regulated peroxisome proliferator-activated receptor γ (PPARγ) in lung epithelial cells promotes a PPARγ agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD)
. 289:6383-6393.
2014
Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes
. 289:5330-5339.
2014
Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-Hydroxyeicosatetraenoic acid partly via Protein Kinase C
e
-mediated Zona Occludens-1 Phosphorylation at Threonine 770/772
. 289:3148-3163.
2014
Increased ribozyme activity in crowded solutions
. 289:2972-2977.
2014
Defining the communication between agonist and coactivator binding in the retinoid x receptor α ligand binding domain
. 289:814-826.
2014
Conserved allosteric hot spots in the transmembrane domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channels and Multidrug Resistance Protein (MRP) pumps
. 289:19942-19957.
2014
Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion
. 289:25276-25286.
2014
The oncometabolite fumarate promotes pseudohypoxia through noncanonical activation of NF-κB signaling
. 289:24691-24699.
2014
The retinaldehyde reductase activity of dhrs3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis
. 289:14868-14880.
2014
Transient receptor potential channel 6 (trpc6) protects podocytes during complement-Mediated glomerular disease
. 288:36598-36609.
2013
MiR-125a-5p regulates differential activation of macrophages and inflammation
. 288:35428-35436.
2013
Triptolide-induced cell death in Pancreatic cancer is mediated by O-GlcNAc modification of transcription factor Sp1
. 288:33927-33938.
2013
The RclR protein is a reactive chlorine-specific transcription factor in escherichia coli
. 288:32574-32584.
2013
Reduction of synaptojanin 1 accelerates aβ clearance and attenuates cognitive deterioration in an alzheimer mouse model
. 288:32050-32063.
2013
MCF-7 cells expressing nuclear associated lysyl oxidase-like 2 (LOXL2) exhibit an epithelial-to-Mesenchymal transition (EMT) phenotype and are highly invasive in Vitro
. 288:30000-30008.
2013
Cross-talk from β-adrenergic receptors modulates α
2A
-adrenergic receptor endocytosis in sympathetic neurons via protein kinase A and spinophilin
. 288:29193-29205.
2013
The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death
. 288:29047-29055.
2013
Cluster of differentiation 38 (CD38) mediates bile acid-induced acinar cell injury and pancreatitis through cyclic ADP-ribose and intracellular calcium release
. 288:27128-27137.
2013
Discovery of streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units
. 288:25976-25985.
2013
Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosis
. 288:26013-26026.
2013
Ankyrin repeat domain protein 2 and inhibitor of DNA binding 3 cooperatively inhibit myoblast differentiation by physical interaction.
. 288:24560-24568.
2013
FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells
. 288:23194-23202.
2013
Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density
. 288:22248-22256.
2013
Epigallocatechin gallate (EGCG) stimulates autophagy in vascular endothelial cells: A potential role for reducing lipid accumulation
. 288:22693-22705.
2013
Streptococcus pneumoniae serotype 11D has a bispecific glycosyltransferase and expresses two different capsular polysaccharide repeating units
. 288:21945-21954.
2013
Structural and biophysical characterization of the interactions between the death domain of fas receptor and calmodulin
. 288:21898-21908.
2013
An undesired effect of chemotherapy: Gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factorκb- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4
. 288:21197-21207.
2013
Accelerated development of pulmonary fibrosis via Cu,Zn-superoxide dismutase-induced alternative activation of macrophages
. 288:20745-20757.
2013
Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function
. 288:18022-18034.
2013
P39, the primary activator for cyclin-dependent kinase 5 (CDK5) in oligodendroglia, is essential for oligodendroglia differentiation and myelin repair
. 288:18047-18057.
2013
Converting nonhydrolyzable nucleotides to strong cystic fibrosis transmembrane conductance regulator (CFTR) agonists by gain of function (GOF) mutations
. 288:17122-17133.
2013
A role for cargo in Arf-dependent adaptor recruitment
. 288:14788-14804.
2013
Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy
. 288:15194-15210.
2013
Calreticulin regulates transforming growth factor-β-stimulated extracellular matrix production
. 288:14584-14598.
2013
NemR is a bleach-sensing transcription factor
. 288:13789-13798.
2013
Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to smoothened-targeting Hedgehog inhibition
. 288:11824-11833.
2013
The Sec7 guanine nucleotide exchange factor GBF1 regulates membrane recruitment of BIG1 and BIG2 guanine nucleotide exchange factors to the trans-Golgi network (TGN)
. 288:11532-11545.
2013
Heparanase regulates secretion, composition, and function of tumor cell-derived exosomes
. 288:10093-10099.
2013
BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G
1
phase of the cell cycle
. 288:8966-8976.
2013
DNA binding by the ribosomal DNA transcription factor Rrn3 is essential for ribosomal DNA transcription
. 288:9135-9144.
2013
Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7).
. 288:9165-9176.
2013
SON protein regulates GATA-2 through transcriptional control of the microRNA 23a~27a~24-2 cluster.
. 288:5381-5388.
2013
Characterization of an apparently novel β-cell line-enriched 80-88 kDa transcriptional activator of the MafA and Pdxl genes
. 288:3795-3803.
2013
Structural arrangement of the intracellular Ca
2+
binding domains of the cardiac Na
+
/Ca
2+
exchanger (NCX1.1): Effects of Ca
2+
binding
. 288:4194-4207.
2013
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonucleasethat translocates to the nucleus during apoptosis
. 288:3460-3468.
2013
Four of the most common mutations in primary hyperoxaluria type 1 unmask the cryptic mitochondrial targeting sequence of alanine:glyoxylate aminotransferase encoded by the polymorphic minor allele
. 288:2475-2484.
2013
Dynamin-mediated nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells (Journal of Biological Chemistry (2012) 287, (28932-28942))
. 288:1277.
2013
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly (ADP-ribose) polymerase-regulated DNAS1...
. 288:3460-3468.
2013
The enzymatic activity of apoptosis-inducing factor supports energy metabolism benefiting the growth and invasiveness of advanced prostate cancer cells.
. 287:43862-43875.
2012
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells
. 287:42084-42092.
2012
Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma
. 287:41288-41296.
2012
CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: Implications for bidirectional tumor-stromal interactions
. 287:39115-39124.
2012
Modification of STIM1 by O-linked N-Acetylglucosamine (O-GlcNAc) attenuates store-operated calcium entry in neonatal cardiomyocytes
. 287:39094-39106.
2012
Glucose deprivation-induced increase in protein O-GlcNAcylation in cardiomyocytes is calcium-dependent
. 287:34419-34431.
2012
The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK)/NRF2 signaling pathway and cytokine release
. 287:33720-33732.
2012
Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease
. 287:32459-32466.
2012
Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function
. 287:32277-32287.
2012
p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells
. 287:30117-30127.
2012
Conformational changes relevant to channel activity and folding within the first nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator
. 287:28480-28494.
2012
Dynamin-mediated nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells
. 287:28932-28942.
2012
Biochemical, genetic, and serological characterization of two capsule subtypes among Streptococcus pneumoniae serotype 20 strains: Discovery of a new pneumococcal serotype
. 287:27885-27894.
2012
Epstein-barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties
. 287:26586-26595.
2012
Targeting the sonic hedgehog pathway in keratocystic odontogenic tumor
. 287:27117-27125.
2012
The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site
. 287:24273-24283.
2012
Low temperature and chemical rescue affect molecular proximity of ΔF508-cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC)
. 287:16781-16790.
2012
Molecular basis of requirement of receptor activator of nuclear factor κB signaling for interleukin 1-mediated osteoclastogenesis
. 287:15728-15738.
2012
G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.
. 287:13674-13685.
2012
Structural characterization of Streptococcus pneumoniae serotype 9A capsule polysaccharide reveals role of glycosyl 6-O-acetyltransferase wcjE in serotype 9V capsule biosynthesis and immunogenicity
. 287:13996-14003.
2012
Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents (Journal of Biological Chemistry (2010) 285, (35406-35417))
. 287:12152.
2012
Noggin is novel inducer of mesenchymal stem cell adipogenesis: Implications for bone health and obesity
. 287:12241-12249.
2012
Heparan sulfate chains of syndecan-1 regulate ectodomain shedding
. 287:9952-9961.
2012
Short chain dehydrogenase/reductase Rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development
. 287:9061-9071.
2012
Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis
. 287:7990-8000.
2012
Latency-associated peptide of transforming growth factor-β1 is not subject to physiological mannose phosphorylation
. 287:7526-7534.
2012
Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms
. 287:4107-4120.
2012
Glioma-specific cation conductance regulates migration and cell cycle progression
. 287:4053-4065.
2012
Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis
. 287:3301-3312.
2012
Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells.
. 287:2459-2467.
2012
Nrf2-dependent Induction of Proteasome and Pa28αβ Regulator Are Required for Adaptation to Oxidative Stress
. 23:10021-31.
2012
O-glcnacylation, novel post-translational modification linking myocardial metabolism and cardiomyocyte circadian clock
. 286:44606-44619.
2011
Nucleolin maintains embryonic stem cell self-renewal by suppression of p53 protein-dependent pathway
. 286:43370-43382.
2011
The structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes (The Journal of Biological Chemistry (2009) 284 (7318-7329))
. 286:43588.
2011
Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "Rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops
. 286:41937-41948.
2011
γ-secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1
. 286:42514-42523.
2011
Phosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate kinase (MAGUK).
. 286:41776-41785.
2011
The Unfolded Protein Response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide transporter 1 (TAP1) mRNA and governs immune regulatory genes
. 286:41862-41870.
2011
Identification of a novel Mcl-1 protein binding motif
. 286:39829-39835.
2011
Loss of tumor suppressor merlin in advanced breast cancer is due to post-translational regulation
. 286:40376-40385.
2011
Distinct functions of evolutionary conserved MSF1 and Late Embryogenesis Abundant (LEA)-like domains in mitochondria
. 286:39141-39152.
2011
ST6Gal-I regulates macrophage apoptosis via α2-6 sialylation of the TNFR1 death receptor
. 286:39654-39662.
2011
Endothelial surface N-glycans mediate monocyte adhesion and are targets for anti-inflammatory effects of peroxisome proliferator-activated receptor γ ligands
. 286:38738-38747.
2011
Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation
. 286:36898-36906.
2011
Comparative structural and molecular characterization of Streptococcus pneumoniae capsular polysaccharide serogroup 10
. 286:35813-35822.
2011
The antidepressant desipramine is an arrestin-biased ligand at the α
2A
-adrenergic receptor driving receptor down-regulation in vitro and in vivo
. 286:36063-36075.
2011
A molecular chaperone mediates a two-protein enzyme complex and glycosylation of serine-rich streptococcal adhesins
. 286:34923-34931.
2011
NMR, biophysical, and biochemical studies reveal the minimal calmodulin binding domain of the HIV-1 matrix protein
. 286:33533-33543.
2011
Mining endonuclease cleavage determinants in genomic sequence data
. 286:32617-32627.
2011
Heparanase-mediated loss of nuclear syndecan-1 enhances Histone Acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype
. 286:30377-30383.
2011
TwoDrosophilaMyosin Transducer Mutants with Distinct Cardiomyopathies Have Divergent ADP and Actin Affinities
. 286:28435-28443.
2011
Structural and functional analysis of a new subfamily of glycosyltransferases required for glycosylation of serine-rich streptococcal adhesins
. 286:27048-27057.
2011
Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions
. 286:25963-25972.
2011
Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival
. 286:26003-26015.
2011
Calmodulin mediates Fas-induced FADD-independent survival signaling in pancreatic cancer cells via activation of Src-Extracellular Signal-regulated Kinase (ERK)
. 286:24776-24784.
2011
Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms
. 286:24855-24864.
2011
TLR2-dependent modulation of osteoclastogenesis by Porphyromonas gingivalis through differential induction of NFATc1 and NF-κB
. 286:24159-24169.
2011
Sialylation of the Fas death receptor by St6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells
. 286:22982-22990.
2011
Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused
. 286:22077-22089.
2011
Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains
. 286:21657-21666.
2011
Cancer cell survival following DNA damage-mediated premature senescence is regulated by mammalian target of rapamycin (mTOR)-dependent inhibition of sirtuin
. 286:19100-19108.
2011
The transcription elongation factor Spt5 influences transcription by RNA polymerase I positively and negatively
. 286:18816-18824.
2011
Yeast transcription elongation factor Spt5 associates with RNA polymerase I and RNA polymerase II directly
. 286:18825-18833.
2011
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection
. 286:16504-16515.
2011
Human papillomavirus (HPV) E7 induces prolonged G
2
following S phase reentry in differentiated human keratinocytes
. 286:15473-15482.
2011
Islet-1 regulates Arx transcription during pancreatic islet α-cell development
. 286:15352-15360.
2011
Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H
2
O
2
generation
. 286:15597-15607.
2011
A unified view of cystic fibrosis transmembrane conductance regulator (CFTR) gating: Combining the allosterism of a ligand-gated channel with the enzymatic activity of an ATP-binding cassette (ABC) transporter
. 286:12813-12819.
2011
Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture
. 286:13550-13560.
2011
Protein-arginine methyltransferase 1 (PRMT1) methylates Ash2L, a shared component of mammalian histone H3K4 methyltransferase complexes
. 286:12234-12244.
2011
Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis
. 286:9612-9622.
2011
Dual functions of T-box 3 (Tbx3) in the control of self-renewal and extraembryonic endoderm differentiation in mouse embryonic stem cells
. 286:8425-8436.
2011
Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes (Journal of Biological Chemistry (2009) 284 (7318-7329))
. 286:8707.
2011
Regulation of histone H2A and H2B deubiquitination and xenopus development by USP12 and USP46
. 286:7190-7201.
2011
Emerging role of α2,6-sialic acid as a negative regulator of galectin binding and function
. 286:5935-5941.
2011
Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity
. 286:6490-6499.
2011
Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-β production
. 286:6117-6127.
2011
Ursolic acid, a pentacyclin triterpene, potentiates trail-induced apoptosis through p53-independent up-regulation of death receptors: Evidence for the role of reactive oxygen species and JNK
. 286:5546-5557.
2011
Identification of nuclear localization, DNA binding, and transactivating mechanisms of krüppel-like zinc finger protein gli-similar 2 (Glis2)
. 286:4749-4759.
2011
Induction of Sirt1 by mechanical stretch of skeletal muscle through the early response factor EGR1 triggers an antioxidative response.
. 286:2559-2566.
2011
Lineage-specific effects of 1,25-dihydroxyvitamin D
3
on the development of effector CD4 T cells
. 286:997-1004.
2011
Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure
. 285:41911-41920.
2010
Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain
. 285:39759-39767.
2010
Structure of human Stabilin-1 Interacting Chitinase-Like Protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity
. 285:39898-39904.
2010
The ecto-enzyme CD38 is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) synthase that couples receptor activation to Ca
2+
mobilization from lysosomes in pancreatic acinar cells
. 285:38251-38259.
2010
Receptor activator of NF-κB (RANK) cytoplasmic IVVY
535-538
motif plays an essential role in tumor necrosis factor-α (TNF)-mediated osteoclastogenesis
. 285:37427-37435.
2010
Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2
. 285:36586-36596.
2010
RANKL up-regulates brain-type creatine kinase via poly(ADP-ribose) polymerase-1 during osteoclastogenesis
. 285:36315-36321.
2010
Modification of cysteine 179 of IκBα kinase by nimbolide leads to down-regulation of NF-κB-regulated cell survival and proliferative proteins and sensitization of tumor cells to chemotherapeutic agents
. 285:35406-35417.
2010
The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes
. 285:35599-35605.
2010
The cystic fibrosis-causing mutation ΔF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis
. 285:35825-35835.
2010
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase
. 285:33154-33164.
2010
γ-Tocotrienol but not γ-tocopherol blocks STAT3 cell signaling pathway through induction of protein-tyrosine phosphatase SHP-1 and sensitizes tumor cells to chemotherapeutic agents
. 285:33520-33528.
2010
Structural insights into serine-rich fimbriae from gram-positive bacteria
. 285:32446-32457.
2010
Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3β.
. 285:29336-29347.
2010
A synonymous single nucleotide polymorphism in ΔF508 CFTR alters the secondary structure of the mRNA and the expression of the mutant protein
. 285:28741-28748.
2010
Factor VIII and platelets synergistically accelerate cleavage of von Willebrand factor by ADAMTS13 under fluid shear stress
. 285:28596-28603.
2010
Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain
. 285:28708-28714.
2010
Proteolytic cleavage of human acid-sensing ion channel 1 by the serine protease matriptase
. 285:27130-27143.
2010
DNAJB6 induces degradation of β-catenin and causes partial reversal of mesenchymal phenotype
. 285:24686-24694.
2010
Rac1-mediated mitochondrial H
2
O
2
generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1
. 285:25062-25073.
2010
Thy-1-integrin α
v
β
5
interactions inhibit lung fibroblast contraction-induced latent transforming growth factor-β1 activation and myofibroblast differentiation
. 285:22382-22393.
2010
Glycosylation patterns of HIV-1 gp120 depend on the type of expressing cells and affect antibody recognition
. 285:20860-20869.
2010
What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology
. 285:19699-19704.
2010
Inflammation anergy in human intestinal macrophages is due to Smad-induced IκBα expression and NF-κB inactivation
. 285:19593-19604.
2010
Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo
. 285:16757-16770.
2010
Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells
. 285:16476-16486.
2010
Oxidative modification of nuclear mitogen-activated protein kinase phosphatase 1 is involved in transforming growth factor β1-induced expression of plasminogen activator inhibitor 1 in fibroblasts
. 285:16239-16247.
2010
Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice
. 285:14521-14533.
2010
The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis
. 285:14152-14159.
2010
A novel glucosyltransferase is required for glycosylation of a serine-rich adhesin and biofilm formation by Streptococcus parasanguinis
. 285:12140-12148.
2010
Lysosome dysfunction triggers Atg7-dependent neural apoptosis
. 285:10497-10507.
2010
Amiloride docking to acid-sensing ion channel-1
. 285:9627-9635.
2010
Inhibition of lung fluid clearance and epithelial Na
+
channels by chlorine, hypochlorous acid, and chloramines
. 285:9716-9728.
2010
Intracellular calreticulin regulates multiple steps in fibrillar collagen expression, trafficking, and processing into the extracellular matrix
. 285:7067-7078.
2010
Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A
2
expression: A role for regulation by SREBP-1
. 285:6693-6705.
2010
BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia
. 285:5085-5096.
2010
Transforming growth factor β1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism
. 285:4278-4290.
2010
Intracellular shuttling and mitochondrial function of thioredoxin- interacting protein
. 285:3997-4005.
2010
Modulation of SCF
β-TrCP
-dependent IκBα ubiquitination by hydrogen peroxide
. 285:2665-2675.
2010
Branched-chain amino acid metabolon: Interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm)
. 285:265-276.
2010
Smad3 differentially regulates the induction of regulatory and inflammatory T cell differentiation
. 284:35283-35286.
2009
Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR). Implications for impaired post-transcriptional regulation of vascular endothelial growth factor
. 284:33989-33998.
2009
Curcumin cross-links cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides and potentiates CFTR channel activity by distinct mechanisms
. 284:30754-30765.
2009
Nutlin-3 affects expression and function of retinoblastoma protein. Role of Retinoblastoma protein in cellular response to nutlin-3
. 284:26315-26321.
2009
Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo
. 284:26085-26095.
2009
NDRG4 is required for cell cycle progression and survival in glioblastoma cells
. 284:25160-25169.
2009
Knockdown of ASIC1 and epithelial sodium channel subunits inhibits glioblastoma whole cell current and cell migration
. 284:24526-24541.
2009
The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin
. 284:22888-22897.
2009
S-glutathionylation of the Rpn2 regulatory subunit inhibits 26 S proteasomal function
. 284:22213-22221.
2009
The 3′-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysis
. 284:22184-22194.
2009
A regulatory loop composed of RAP80-HDM2-p53 provides RAP80-enhanced p53 degradation by HDM2 in response to DNA damage
. 284:19280-19289.
2009
Psalmotoxin-1 docking to human acid-sensing ion channel-1
. 284:17625-17633.
2009
Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells
. 284:16898-16905.
2009
Turning cancer stem cells inside out: An exploration of glioma stem cells signalling pathways
. 284:16705-16709.
2009
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation
. 284:15676-15684.
2009
Myocyte enhancer factor 2 and microphthalmia-associated transcription factor cooperate with NFATc1 to transactivate the V-ATPase d2 promoter during RANKL-induced osteoclastogenesis
. 284:14667-14675.
2009
Epitope-tagged receptor knock-in mice reveal that differential desensitization of α
2
-adrenergic responses is because of ligand-selective internalization
. 284:13233-13243.
2009
Quantification of intermediates formed during the reduction of nitrite by deoxyhemoglobin
. 284:12710-12718.
2009
A kinetic model for chain length modulation of Streptococcus pneumoniae cellubiuronan capsular polysaccharide by nucleotide sugar donor concentrations
. 284:11836-11844.
2009
Characterization of the lipid linkage region and chain length of the cellubiuronic acid capsule of Streptococcus pneumoniae
. 284:11826-11835.
2009
Molecular mechanism of the bifunctional role of lipopolysaccharide in osteoclastogenesis
. 284:12512-12523.
2009
Erratum: Mode of growth hormone action in osteoblasts (Journal of Biological Chemistry (2007) vol. 282 (31666-31674))
. 284:10992.
2009
Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis
. 284:10023-10033.
2009
Functions of the periplasmic loop of the porin MspA from Mycobacterium smegmatis
. 284:10223-10231.
2009
Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury
. 284:7853-7865.
2009
Poly-L-aspartic acid enhances and prolongs gentamicin-mediated suppression of the CFTR-G542X mutation in a cystic fibrosis Mouse model
. 284:6885-6892.
2009
Respiratory syncytial virus inhibits lung epithelial Na
+
channels by up-regulating inducible nitric-oxide synthase
. 284:7294-7306.
2009
Structure of the capsular polysaccharide of pneumococcal serotype 11A reveals a novel acetylglycerol that is the structural basis for 11A subtypes
. 284:7318-7329.
2009
Epidermal growth factor-like repeats of thrombospondins activate phospholipase Cγ and increase epithelial cell migration through indirect epidermal growth factor receptor activation
. 284:6389-6402.
2009
Low intensity shear stress increases endothelial ELR
+
CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathway
. 284:5945-5955.
2009
Humanized mouse model of Cooley's anemia
. 284:4889-4896.
2009
Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)
. 284:3125-3135.
2009
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.
. 283:36698-36710.
2008
Calcium-independent phospholipase A
2
(iPLA
2
β)- mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis
. 283:34819-34832.
2008
Effect of leucine to phenylalanine substitution on the nonpolar face of a class A amphipathic helical peptide on its interaction with lipid: High resolution solution NMR studies of 4F-dimyristoylphosphatidylcholine discoidal complex
. 283:34393-34402.
2008
Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma
. 283:32628-32636.
2008
Phospholipase Cγ2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis
. 283:29593-29601.
2008
Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling
. 283:28354-28360.
2008
Disulfide cross-links reveal conserved features of DNA topoisomerase I architecture and a role for the N terminus in clamp closure
. 283:27767-27775.
2008
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors
. 283:27585-27597.
2008
Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner
. 283:26839-26849.
2008
Proteolytic shedding of ST6Gal-I by BACE1 regulates the glycosylation and function of α4β1 integrins
. 283:26364-26373.
2008
15-Deoxy-Δ
12,14
-prostaglandin J
2
impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase
. 283:24628-24640.
2008
Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-κB/PTEN suppression
. 283:24889-24898.
2008
G2E3 is a dual function ubiquitin ligase required for early embryonic development
. 283:22304-22315.
2008
Sialylation of β1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis
. 283:22177-22185.
2008
Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase
. 283:20299-20308.
2008
Bone morphogenetic protein 2 mediates dentin sialophosphoprotein expression and odontoblast differentiation via NF-Y signaling
. 283:19359-19370.
2008
Heme oxygenase-1-derived carbon monoxide induces the Mycobacterium tuberculosis dormancy regulon
. 283:18032-18039.
2008
Rv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteins
. 283:17827-17837.
2008
NF-κB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser
276
) phosphorylation via the MEK-MSK1 signaling pathway
. 283:16391-16399.
2008
Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2
. 283:15789-15798.
2008
Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling
. 283:15319-15327.
2008
Protein kinase A phosphorylation of spinophilin modulates its interaction with the α
2A
-adrenergic receptor (AR) and alters temporal properties of α
2A
AR internalization
. 283:14516-14523.
2008
The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response
. 283:12154-12165.
2008
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal
. 283:8412-8422.
2008
Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells
. 283:7438-7444.
2008
Mutation of Gly
721
alters DNA topoisomerase I active site architecture and sensitivity to camptothecin
. 283:3305-3315.
2008
Cystic fibrosis transmembrane conductance regulator trafficking is mediated by the COPI coat in epithelial cells
. 283:833-839.
2008
A role for the transcriptional coactivator PGC-1α in muscle refueling
. 282:36642-36651.
2007
Molecular proximity of cystic fibrosis transmembrane conductance regulator and epithelial sodium channel assessed by fluorescence resonance energy transfer
. 282:36481-36488.
2007
Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12
. 282:35621-35628.
2007
Conditional disruption of calcineurin B1 in osteoblasts increases bone formation and reduces bone resorption
. 282:35318-35327.
2007
Microtubule motors regulate I
SOC
activation necessary to increase endothelial cell permeability
. 282:34801-34808.
2007
Participation of the chaperone Hsc70 in the trafficking and functional expression of ASIC2 in glioma cells
. 282:34381-34391.
2007
Mode of growth hormone action in osteoblasts
. 282:31666-31674.
2007
NR4A orphan nuclear receptors modulate insulin action and the glucose transport system: Potential role in insulin resistance
. 282:31525-31533.
2007
Microsomal triglyceride transfer protein activity is not required for the initiation of apolipoprotein B-containing lipoprotein assembly in McA-RH7777 cells
. 282:28597-28608.
2007
Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A
2
. 282:27100-27114.
2007
Heteromeric assembly of acid-sensitive ion channel and epithelial sodium channel subunits
. 282:25548-25559.
2007
Hyperphagia-mediated obesity in transgenic mice misexpressing the RNA-editing enzyme ADAR2
. 282:22448-22459.
2007
Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6
. 282:22460-22471.
2007
c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages.
. 282:18980-18990.
2007
Learning-induced glutamate receptor phosphorylation resembles that induced by long term potentiation
. 282:18100-18107.
2007
Identification of a HoxA10 activation domain necessary for transcription of the gene encoding β3 integrin during myeloid differentiation
. 282:16846-16859.
2007
Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5
. 282:16511-16520.
2007
Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: Importance of vicinal cysteines 504 and 505
. 282:14403-14412.
2007
Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and fyn
. 282:13736-13745.
2007
Heparanase enhances syndecan-1 shedding: A novel mechanism for stimulation of tumor growth and metastasis
. 282:13326-13333.
2007
N-MYC regulates focal adhesion kinase expression in human neuroblastoma
. 282:12503-12516.
2007
A novel branched-chain amino acid metabolon: Protein-protein interactions in a supramolecular complex
. 282:11893-11903.
2007
Green fluorescent protein impairs actin-myosin interactions by binding to the actin-binding site of myosin
. 282:10465-10471.
2007
Alterations in linker flexibility suppress DNA topoisomerase I mutant-induced cell lethality
. 282:9855-9864.
2007
JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells
. 282:6875-6886.
2007
Prevention of peroxynitrite-induced apoptosis of motor neurons and PC12 Cells by tyrosine-containing peptides
. 282:6324-6337.
2007
Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the nucleotide-binding domains
. 282:4533-4544.
2007
H
2
O
2
-induced kinetic and chemical modifications of smooth muscle myosin: Correlation to effects of H
2
O
2
on airway smooth muscle
. 282:4336-4344.
2007
The effect of class A scavenger receptor deficiency in bone
. 282:4653-4660.
2007
ApoA-I mimetic peptides with differing ability to inhibit atherosclerosis also exhibit differences in their interactions with membrane bilayers
. 282:1980-1988.
2007
Suppression of calpain-dependent cleavage of the CDK5 activator p35 to p25 by site-specific phosphorylation
. 282:1687-1694.
2007
Concerted action of exonuclease and gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)
n
- and (GAA)
n
-derived secondary structures formed during maturation of Okazaki fragments
. 282:3465-3477.
2007
Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD
. 282:4035-4044.
2007
The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.
. 282:445-453.
2007
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network
. 281:40515-40526.
2006
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network
. 281:40515-40526.
2006
Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells
. 281:39819-39830.
2006
Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G
1
cell cycle arrest
. 281:39480-39491.
2006
Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor γ chain to induce innate immune responses
. 281:38854-38866.
2006
SNARE status regulates tether recruitment and function in homotypic COPII vesicle fusion
. 281:38825-38833.
2006
Interregulation of proton-gated Na
+
channel 3 and cystic fibrosis transmembrane conductance regulator
. 281:36960-36968.
2006
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators
. 281:35686-35698.
2006
Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex
. 281:35088-35096.
2006
Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-β
. 281:33971-33981.
2006
A cysteine-scanning mutagenesis study of transmembrane domain 8 of the electrogenic sodium/bicarbonate cotransporter NBCe1
. 281:32417-32427.
2006
Function of the two xenopus Smad4s in early frog development
. 281:30794-30803.
2006
Arrestin serves as a molecular switch, linking endogenous α2-adrenergic receptor to SRC-dependent, but not SRC-independent, ERK activation
. 281:25948-25955.
2006
Non-B DNA conformations formed by long repeating tracts of myotonic dystrophy type 1, myotonic dystrophy type 2, and Friedreich's ataxia genes, not the sequences per se, promote mutagenesis in Flanking regions
. 281:24531-24543.
2006
Pescadillo interacts with the cadmium response element of the human heme oxygenase-1 promoter in renal epithelial cells
. 281:24423-24430.
2006
Phosphorylation of protein phosphatase inhibitor-1 by protein kinase C
. 281:24322-24335.
2006
Role of Bmi1 in H2A ubiquitylation and Hox gene silencing
. 281:22537-22544.
2006
Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A
2
and effects of metabolic stress on glucose homeostasis
. 281:20958-20973.
2006
Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α)-deficient mice
. 281:19000-19008.
2006
Surface expression of ASIC2 inhibits the amiloride-sensitive current and migration of glioma cells
. 281:19220-19232.
2006
Nox1-dependent reactive oxygen generation is regulated by Rac1
. 281:17718-17726.
2006
Apoptosis induction by activator protein 2α involves transcriptional repression of Bcl-2
. 281:16207-16219.
2006
Differential binding of erythroid krupple-like factor to embryonic/fetal globin gene promoters during development
. 281:16052-16057.
2006
Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus
. 281:15763-15773.
2006
Parkin Protects against Mitochondrial Toxins and β-Amyloid Accumulation in Skeletal Muscle Cells
. 281:12809-12816.
2006
Regulation of surface localization of the small conductance Ca
2+
-activated potassium channel, Sk2, through direct phosphorylation by cAMP-dependent protein kinase
. 281:11769-11779.
2006
T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects
. 281:11992-12000.
2006
Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione
. 281:9190-9199.
2006
9-O-acetylation of exogenously added ganglioside GD3: The GD3 molecule induces its own O-acetylation machinery
. 281:7825-7833.
2006
δ-subunit confers novel biophysical features to αβγ- human epithelial sodium channel (ENaC) via a physical interaction
. 281:8233-8241.
2006
Association of a model class A (apolipoprotein) amphipathic α helical peptide with lipid: High resolution NMR studies of peptide-lipid discoidal complexes
. 281:6511-6519.
2006
Role of the carbohydrate binding site of the Streptococcus pneumoniae capsular polysaccharide type 3 synthase in the transition from oligosaccharide to polysaccharide synthesis
. 281:6283-6289.
2006
Hemoglobin is expressed by alveolar epithelial cells
. 281:5668-5676.
2006
Topology of the porin MspA in the outer membrane of Mycobacterium smegmatis
. 281:5908-5915.
2006
A novel receptor activator of NF-κB (RANK) cytoplasmic motif plays an essential role in osteoclastogenesis by committing macrophages to the osteoclast lineage
. 281:4678-4690.
2006
The histone acetyltransferase NCOAT contains a zinc finger-like motif involved in substrate recognition
. 281:3918-3925.
2006
Mutations in the amino terminus of the cystic fibrosis transmembrane conductance regulator enhance endocytosis
. 281:3329-3334.
2006
Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1
. 281:3604-3613.
2006
Insulin enhances growth hormone induction of the MEK/ERK signaling pathway
. 281:982-992.
2006
Effects of stable suppression of group VIA phospholipase A
2
expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells
. 281:187-198.
2006
Erratum: Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4 (Journal of Biological Chemistry (2001) 276 (41325-41335))
. 280:43280.
2005
Receptor activator of NF-κB (RANK) cytoplasmic motif,
369
PFQEP
373
, plays a predominant role in osteoclast survival in part by activating Akt/PKB and its downstream effector AFX/FOXO4
. 280:43064-43072.
2005
Fatty acid transduction of nitric oxide signaling: Multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands
. 280:42464-42475.
2005
HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo
. 280:40066-40073.
2005
The inv(16) cooperates with ARF haploinsufficiency to induce acute myeloid leukemia
. 280:40097-40103.
2005
A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering β1 integrin sialylation
. 280:37610-37615.
2005
Increased negative superhelical density in vivo enhances the genetic instability of triplet repeat sequences
. 280:37366-37376.
2005
WNK1 activates SGK1 by a phosphatidylinositol 3-kinase-dependent and non-catalytic mechanism
. 280:34218-34223.
2005
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression
. 280:33132-33140.
2005
The Gα
o/i
-coupled cannabinoid receptor-mediated neurite outgrowth involves rap regulation of Src and Stat3
. 280:33426-33434.
2005
Dentin sialoprotein and dentin phosphoprotein overexpression during amelogenesis
. 280:31991-31998.
2005
Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action
. 280:31679-31685.
2005
Point mutations in the proline-rich region of p22
phox
are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation
. 280:31859-31869.
2005
The reaction between nitrite and deoxyhemoglobin. Reassessment of reaction kinetics and stoichiometry.
. 280:31126-31131.
2005
Differential regulation of dentin sialophosphoprotein expression by Runx2 during odontoblast cytodifferentiation.
. 280:29717-29727.
2005
The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor
. 280:29428-29434.
2005
Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor-α-positive breast cancer cells
. 280:27022-27028.
2005
Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs
. 280:23622-23630.
2005
Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage
. 280:23566-23575.
2005
Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1
. 280:24227-24237.
2005
Phosphorylation of Ser
24
in the pleckstrin homology domain of insulin receptor substrate-1 by mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: Cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance
. 280:23173-23183.
2005
Blue light induces mitochondrial DNA damage and free radical production in epithelial cells
. 280:21061-21066.
2005
Oxysterols inhibit phosphatidylcholine synthesis via ERK docking and phosphorylation of CTP:phosphocholine cytidylyltransferase
. 280:21577-21587.
2005
The unfolded protein response modulates toxicity of the expanded glutamine androgen receptor
. 280:21264-21271.
2005
The C-terminal sterile α motif and the extreme C terminus regulate the transcriptional activity of the α isoform of p73
. 280:20111-20119.
2005
Determination of aberrant O-glycosylation in the IgA1 hinge region by electron capture dissociation Fourier transform-ion cyclotron resonance mass spectrometry
. 280:19136-19145.
2005
Fatty acid transduction of nitric oxide signaling: Nitrolinoleic acid is a hydrophobically stabilized nitric oxide donor
. 280:19289-19297.
2005
Growth hormone receptor is a target for presenilin-dependent γ-secretase cleavage
. 280:19331-19342.
2005
Interleukin-1β decreases expression of the epithelial sodium channel α-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway
. 280:18579-18589.
2005
Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation
. 280:15872-15879.
2005
Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through Gα
o/i
-triggered proteasomal degradation of Rap1GAPII
. 280:11413-11421.
2005
The small heat shock protein αB-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3
. 280:11059-11066.
2005
Calmodulin and calmodulin-dependent kinase IIα regulate osteoblast differentiation by controlling c-fos expression
. 280:7049-7059.
2005
Group VIA phospholipase A
2
forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIβ expressed in pancreatic islet β-cells
. 280:6840-6849.
2005
Fragile X-related protein FXR1P regulates proinflammatory cytokine tumor necrosis factor expression at the post-transcriptional level
. 280:5750-5763.
2005
Extracellular signal-regulated kinases 1/2 control claudin-2 expression in Madin-Darby canine kidney strain I and II cells
. 280:3780-3788.
2005
Identification of an invasion regulatory domain within the core protein of syndecan-1
. 280:3467-3473.
2005
The adaptor protein HSH2 attenuates apoptosis in response to ligation of the B cell antigen receptor complex on the B lymphoma cell line, WEHI-231
. 280:3507-3515.
2005
EVI1 abrogates interferon-α response by selectively blocking PML induction
. 280:428-436.
2005
Functional identification of three receptor activator of NF-κB cytoplasmic motifs mediating osteoclast differentiation and function
. 279:54759-54769.
2004
Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin
. 279:54502-54509.
2004
Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I
. 279:54069-54078.
2004
Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities
. 279:53665-53673.
2004
Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function
. 279:53435-53441.
2004
Two homologous apolipoprotein AI mimetic peptides: Relationship between membrane interactions and biological activity
. 279:51404-51414.
2004
Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids
. 279:49931-49939.
2004
Thrombospondin induces RhoA inactivation through FAK-dependent signaling to stimulate focal adhesion disassembly
. 279:48983-48992.
2004
The tryptophan-rich motifs of the thrombospondin type 1 repeats bind VLAL motifs in the latent transforming growth factor-β complex
. 279:47633-47642.
2004
Brg-1 is required for maximal transcription of the human matrix metalloproteinase-2 gene
. 279:46326-46334.
2004
Intranuclear trafficking: Organization and assembly of regulatory machinery for combinatorial biological control
. 279:43363-43366.
2004
The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain
. 279:43581-43588.
2004
Hairpin structure-forming propensity of the (CCTG-CAGG) Tetranucleotide Repeats Contributes to the Genetic Instability Associated with Myotonic Dystrophy Type 2
. 279:41715-41726.
2004
Regulation of the Cell Type-specific dentin sialophosphoprotein gene expression in mouse odontoblasts by a novel transcription repressor and an activator CCAAT-binding factor.
. 279:42182-42191.
2004
Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscle
. 279:39593-39603.
2004
Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression
. 279:38577-38589.
2004
Male mice that do not express Group VIA Phospholipase A
2
produce spermatozoa with impaired motility and have greatly reduced fertility
. 279:38194-38200.
2004
The Ca
2+
homeostasis defects in a pgm2Δ strain of Saccharomyces cerevisiae are caused by excessive vacuolar Ca
2+
uptake mediated by the Ca
2+
-ATPase Pmc1p
. 279:38495-38502.
2004
Molecular interactions that confer latency to transforming growth factor-β
. 279:38032-38039.
2004
Glucose up-regulates thrombospondin 1 gene transcription and transforming growth factor-β activity through antagonism of cGMP-dependent protein kinase repression via upstream stimulatory factor 2
. 279:34311-34322.
2004
Nox3 regulation by NOXO1, p47
phox
, and p67
phox
. 279:34250-34255.
2004
Steroids and exogenous γ-ENaC subunit modulate cation channels formed by α-ENaC in human B lymphocytes
. 279:33206-33212.
2004
Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium
. 279:30945-30953.
2004
Phosphorylation of mouse glutamine-fructose-6-phosphate amidotransferase 2 (GFAT2) by cAMP-dependent protein kinase increases the enzyme activity
. 279:29988-29993.
2004
A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin
. 279:27518-27524.
2004
Apolipoprotein A-I-stimulated apolipoprotein E secretion from human macrophages is independent of cholesterol efflux
. 279:25966-25977.
2004
Aromatic residue position on the nonpolar face of class A amphipathic helical peptides determines biological activity
. 279:26509-26517.
2004
Thrombospondin-1-induced focal adhesion disassembly in fibroblasts requires Thy-1 surface expression, lipid raft integrity, and Src activation
. 279:23510-23516.
2004
Efficient intracellular processing of the endogenous cystic fibrosis transmembrane conductance regulator in epithelial cell lines
. 279:22578-22584.
2004
Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity
. 279:22092-22101.
2004
Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: Impact on growth hormone signaling
. 279:20898-20905.
2004
Evidence that the TM1-TM2 loop contributes to the ρ1 GABA receptor pore
. 279:20906-20914.
2004
The deubiquitinating enzyme Doa4p protects cells from DNA topoisomerase I poisons
. 279:21271-21281.
2004
A Redox-controlled Molecular Switch Revealed by the Crystal Structure of a Bacterial Heme PAS Sensor
. 279:20186-20193.
2004
Functional analysis of the rod photoreceptor cGMP phosphodiesterase α-subunit gene promoter: Nrl and Crx are required for full transcriptional activity
. 279:19800-19807.
2004
Selective Deficiency of the "Bone-related" Runx2-II Unexpectedly Preserves Osteoblast-mediated Skeletogenesis
. 279:20307-20313.
2004
Deletion of Dentin Matrix Protein-1 Leads to a Partial Failure of Maturation of Predentin into Dentin, Hypomineralization, and Expanded Cavities of Pulp and Root Canal during Postnatal Tooth Development
. 279:19141-19148.
2004
Intercellular Adhesion Molecule-1 (ICAM-1) Regulates Endothelial Cell Motility through a Nitric Oxide-dependent Pathway
. 279:19230-19238.
2004
Mitochondrial Dysfunction and Oxidative Damage inparkin-deficient Mice
. 279:18614-18622.
2004
Extracellular ATP-mediated Signaling for Survival in Hyperoxia-induced Oxidative Stress
. 279:16317-16325.
2004
PIKE (Phosphatidylinositol 3-Kinase Enhancer)-A GTPase Stimulates Akt Activity and Mediates Cellular Invasion
. 279:16441-16451.
2004
Cyclic AMP activation of the extracellular signal-regulated kinases 1 and 2: Implications for intestinal cell survival through the transient inhibition of apoptosis
. 279:14828-14834.
2004
Homocysteine Increases the Expression of Vascular Endothelial Growth Factor by a Mechanism Involving Endoplasmic Reticulum Stress and Transcription Factor ATF4
. 279:14844-14852.
2004
Smad4 Protein Stability Is Regulated by Ubiquitin Ligase SCF
β-TrCP1
. 279:14484-14487.
2004
Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase: Evolutionary conservation of product inhibition
. 279:12769-12776.
2004
Molecules Mimicking Smad1 Interacting with Hox Stimulate Bone Formation
. 279:11313-11319.
2004
Extracellular Zinc and ATP Restore Chloride Secretion across Cystic Fibrosis Airway Epithelia by Triggering Calcium Entry
. 279:10720-10729.
2004
Amphetamine regulation of dopamine transport: Combined measurements of transporter currents and transporter imaging support the endocytosis of an active carrier
. 279:8966-8975.
2004
Evolutionary Trace of G Protein-coupled Receptors Reveals Clusters of Residues That Determine Global and Class-specific Functions
. 279:8126-8132.
2004
Heparanase degrades syndecan-1 and perlecan heparan sulfate: Functional implications for tumor cell invasion
. 279:8047-8055.
2004
Relationship between growth rate and ATP concentration in escherichia coli: A bioassay for available cellular ATP
. 279:8262-8268.
2004
Resistance of mitochondrial DNA-depleted cells against cell death: Role of mitochondrial superoxide dismutase
. 279:7512-7520.
2004
The Role of Pre-H2 Domains of α- and δ-Epithelial Na
+
Channels in Ion Permeation, Conductance, and Amiloride Sensitivity
. 279:8428-8440.
2004
Structure-dependent Recombination Hot Spot Activity of GAA·TTC Sequences from Intron 1 of the Friedreich's Ataxia Gene
. 279:6444-6454.
2004
NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain
. 279:4737-4742.
2004
Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines
. 279:3662-3670.
2004
Selective Disruption of Lysosomes in HeLa Cells Triggers Apoptosis Mediated by Cleavage of Bid by Multiple Papain-like Lysosomal Cathepsins
. 279:3578-3587.
2004
Transcription Factor B Contacts Promoter DNA Near the Transcription Start Site of the Archaeal Transcription Initiation Complex
. 279:2825-2831.
2004
Breast Cancer Metastasis Suppressor 1 (BRMS1) Forms Complexes with Retinoblastoma-binding Protein 1 (RBP1) and the mSin3 Histone Deacetylase Complex and Represses Transcription
. 279:1562-1569.
2004
Mutation of CpGs in the Murine Stem Cell Virus Retroviral Vector Long Terminal Repeat Represses Silencing in Embryonic Stem Cells
. 279:34-41.
2004
Cell Cycle Arrest and Apoptosis Induction by Activator Protein 2α (AP-2α) and the Role of p53 and p21
WAF1/CIP1
in AP-2α-mediated Growth Inhibition
. 278:52093-52101.
2003
Respiratory Syncytial Virus Up-regulates TLR4 and Sensitizes Airway Epithelial Cells to Endotoxin
. 278:53035-53044.
2003
The Intermediate S
1
′ Pocket of the Endometase/ Matrilysin-2 Active Site Revealed by Enzyme Inhibition Kinetic Studies, Protein Sequence Analyses, and Homology Modeling
. 278:51646-51653.
2003
Function of γ-Aminobutyric Acid Receptor/Channel ρ
1
Subunits in Spinal Cord
. 278:48321-48329.
2003
Active Nitric Oxide Produced in the Red Cell under Hypoxic Conditions by Deoxyhemoglobin-mediated Nitrite Reduction
. 278:46349-46356.
2003
Cleavage of the ADAMTS13 Propeptide Is Not Required for Protease Activity
. 278:46643-46648.
2003
Vitamin D Inhibits G
1
to S Progression in LNCaP Prostate Cancer Cells through p27
Kip1
Stabilization and Cdk2 Mislocalization to the Cytoplasm
. 278:46862-46868.
2003
The Extracellular Domain Determines the Kinetics of Desensitization in Acid-sensitive Ion Channel 1
. 278:45240-45247.
2003
Transforming Growth Factor-β1 Decreases Expression of the Epithelial Sodium Channel αENaC and Alveolar Epithelial Vectorial Sodium and Fluid Transport via an ERK1/2-dependent Mechanism
. 278:43939-43950.
2003
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons
. 278:43628-43635.
2003
Cytosolic Arl2 Is Complexed with Cofactor D and Protein Phosphatase 2A
. 278:40829-40836.
2003
Evidence for an Intracellular ADP-ribosyl Cyclase/NAD
+
-glycohydrolase in Brain from CD38-deficient Mice
. 278:40670-40678.
2003
Rapid tau aggregation and delayed hippocampal neuronal death induced by persistent thrombin signaling
. 278:37681-37689.
2003
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: Implications in prostate cancer
. 278:36868-36875.
2003
A Biochemical Characterization of the Adeno-associated Virus Rep40 Helicase
. 278:34011-34017.
2003
Mice lacking phosphatidylinositol transfer protein-α exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia
. 278:33501-33518.
2003
Control of mitochondrial respiration by NO
.
, Effects of low oxygen and respiratory state
. 278:31603-31609.
2003
Spinophilin stabilizes cell surface expression of α
2B
-adrenergic receptors
. 278:32405-32412.
2003
Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13
. 278:30136-30141.
2003
Reversible inhibition of cytochrome c oxidase by peroxynitrite proceeds through ascorbate-dependent generation of nitric oxide
. 278:27520-27524.
2003
Involvement of upstream stimulatory factors 1 and 2 in RANKL-induced transcription of tartrate-resistant acid phosphatase gene during osteoclast differentiation.
. 278:20603-20611.
2003
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells: Modulation of EGF-induced trafficking and signaling
. 278:18902-18913.
2003
The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer
. 278:18235-18240.
2003
The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein
. 278:17557-17565.
2003
Acid-sensing ion channels in malignant gliomas
. 278:15023-15034.
2003
Smad4 as a transcription corepressor for estrogen receptor α
. 278:15192-15200.
2003
Heparan sulfate regulates targeting of syndecan-1 to a functional domain on the cell surface
. 278:12888-12893.
2003
Sustained calcium entry through P2X nucleotide receptor channels in human airway epithelial cells
. 278:13398-13408.
2003
Amphetamine-induced dopamine efflux: A voltage-sensitive and intracellular Na
+
-dependent mechanism
. 278:12070-12077.
2003
The core of the tetrameric mycobacterial porin MspA is an extremely stable β-sheet domain
. 278:8678-8685.
2003
A novel active DNA topoisomerase I in Leishmania donovani
. 278:3521-3526.
2003
Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2
. 278:4135-4144.
2003
Nitric oxide-dependent generation of reactive species in sickle cell disease: Actin tyrosine nitration induces defective cytoskeletal polymerization
. 278:4194-4204.
2003
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding: Determination of extracellular domain stem region cleavage site
. 277:50510-50519.
2002
Regulated interactions of the α
2A
adrenergic receptor with spinophilin, 14-3-3ζ, and arrestin 3
. 277:50589-50596.
2002
Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression
. 277:49952-49957.
2002
Regulation of inositol phospholipid binding and signaling through syndecan-4
. 277:49296-49303.
2002
Conserved residues in the putative catalytic triad of human bile acid coenzyme A:Amino acid N-acyltransferase
. 277:47270-47275.
2002
Intracellular glucose 1-phosphate and glucose 6-phosphate levels modulate Ca
2+
homeostasis in Saccharomyces cerevisiae
. 277:45751-45758.
2002
Protein kinase C isoform antagonism controls BNaC2 (ASIC1) function
. 277:45734-45740.
2002
Extracellular ATP is an autocrine/paracrine regulator of hypoxia-induced adventitial fibroblast growth: Signaling through extracellular signal-regulated kinase-1/2 and the Egr-1 transcription factor
. 277:44638-44650.
2002
Reactive oxygen nitrogen species decrease cystic fibrosis transmembrane conductance regulator expression and cAMP-mediated Cl
-
secretion in airway epithelia
. 277:43041-43049.
2002
The CY domain of the FcγRIa α-chain (CD64) alters γ-chain tyrosine-based signaling and phagocytosis
. 277:41287-41293.
2002
PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator
. 277:40099-40105.
2002
Sticky DNA, a long GAA·GAA·TTC triplex that is formed intramolecularly, in the sequence of intron 1 of the frataxin gene
. 277:39217-39227.
2002
Sticky DNA: Effect of the polypurine·polypyrimidine sequence
. 277:39228-39234.
2002
A gnotobiotic transgenic mouse model for studying interactions between small intestinal enterocytes and intraepithelial lymphocytes
. 277:37811-37819.
2002
A tetrameric porin limits the cell wall permeability of Mycobacterium smegmatis
. 277:37567-37572.
2002
CD40-mediated activation of NF-κB in airway epithelial cells
. 277:37054-37063.
2002
The anti-adhesive activity of thrombospondin is mediated by the N-terminal domain of cell surface calreticulin
. 277:37219-37228.
2002
p38 and activating transcription factor-2 involvement in osteoblast osmotic response to elevated extracellular glucose
. 277:37212-37218.
2002
Long CTG·CAG repeat sequences markedly stimulate intramolecular recombination
. 277:34087-34100.
2002
Long CTG·CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination
. 277:34074-34086.
2002
Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts
. 277:33632-33640.
2002
Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors
. 277:32830-32836.
2002
Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA.
. 277:32992-33000.
2002
RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor
. 277:32379-32388.
2002
Identification of Glis1, a novel Gli-related, Krüppel-like zinc finger protein containing transactivation and repressor functions
. 277:30901-30913.
2002
Evidence that the human gene for prostate short-chain dehydrogenase/ reductase (PSDR1) encodes a novel retinal reductase (RalR1)
. 277:28909-28915.
2002
Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation
. 277:28384-28393.
2002
Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer
. 277:25431-25438.
2002
c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells
. 277:23065-23075.
2002
Thrombospondin stimulates focal adhesion disassembly through G
i-
and phosphoinositide 3-kinase-dependent ERK activation
. 277:20453-20460.
2002
Specific modification of mitochondrial protein thiols in response to oxidative stress. A proteomics approach
. 277:17048-17056.
2002
The promoter of the human proliferating cell nuclear antigen gene is not sufficient for cell cycle-dependent regulation in organotypic cultures of keratinocytes
. 277:17271-17280.
2002
Critical role of tumor necrosis factor-α and NF-κB in interferon-γ-induced CD40 expression in microglia/macrophages
. 277:13796-13803.
2002
Characterization of Glis2, a novel gene encoding a Gli-related, Krüppel-like transcription factor with transactivation and repressor functions. Roles in kidney development and neurogenesis
. 277:10139-10149.
2002
Nitric oxide and cGMP-dependent protein kinase regulation of glucose-mediated thrombospondin 1-dependent transforming growth factor-β activation in mesangial cells
. 277:9880-9888.
2002
Regulation of the murine Nfatc1 gene by NFATc2
. 277:10704-10711.
2002
Characterization of murine sphingosine-1-phosphate phosphohydrolase.
. 277:8920-8927.
2002
Anionic phospholipids regulate native and expressed epithelial sodium channel (ENaC)
. 277:7641-7644.
2002
Hydrostatic pressure induces the fusion-active state of enveloped viruses
. 277:8433-8439.
2002
Up-regulation of acid-gated Na
+
channels (ASICs) by cystic fibrosis transmembrane conductance regulator co-expression in Xenopus oocytes
. 277:8395-8405.
2002
A T cell-specific enhancer of the human CD40 ligand gene
. 277:7386-7395.
2002
Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells
. 277:6858-6863.
2002
Interleukin-4 reversibly inhibits osteoclastogenesis via inhibition of NF-κB and mitogen-activated protein kinase signaling
. 277:6622-6630.
2002
Active site mutations in DNA topoisomerase I distinguish the cytotoxic activities of camptothecin and the indolocarbazole, rebeccamycin
. 277:3813-3822.
2002
The serine protease trypsin cleaves C termini of β- and γ-subunits of epithelial Na
+
channels
. 277:4134-4140.
2002
Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response
. 277:1933-1940.
2002
CCAAT/enhancer-binding proteins (C/EBP) β and δ activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression
. 277:1316-1323.
2002
Molecular cross-talk between the TRAIL and interferon signaling pathways
. 277:575-585.
2002
Respiratory syncytial virus inhibits apoptosis and induces NF-kappa B activity through a phosphatidylinositol 3-kinase-dependent pathway.
. 277:492-501.
2002
Expression of the Streptococcus pneumoniae Type 3 Synthase in Escherichia coli: Assembly of type 3 polysaccharide on a lipid primer
. 276:48831-48839.
2001
Structural basis for pterin antagonism in nitric-oxide synthase: Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
. 276:49133-49141.
2001
CpsB Is a Modulator of Capsule-associated Tyrosine Kinase Activity in Streptococcus pneumoniae
. 276:47966-47974.
2001
Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies.
. 276:47590-47598.
2001
Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureus
. 276:44721-44728.
2001
Poly(A) Polymerase and the Regulation of Cytoplasmic Polyadenylation
. 276:41810-41816.
2001
Sphingosylphosphorylcholine and Lysophosphatidylcholine Are Ligands for the G Protein-coupled Receptor GPR4
. 276:41325-41335.
2001
Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura
. 276:41059-41063.
2001
pH Alterations "Reset" Ca
2+
Sensitivity of Brain Na
+
Channel 2, a Degenerin/Epithelial Na
+
Ion Channel, in Planar Lipid Bilayers
. 276:38755-38761.
2001
Identification of Two Topologically Independent Domains in RAG1 and Their Role in Macromolecular Interactions Relevant to V(D)J Recombination
. 276:37093-37101.
2001
Protein Synthesis-dependent and -independent Regulation of Hippocampal Synapses by Brain-derived Neurotrophic Factor
. 276:37585-37593.
2001
Saccharomyces cerevisiae Protein Pci8p and Human Protein eIF3e/Int-6 Interact with the eIF3 Core Complex by Binding to Cognate eIF3b Subunits
. 276:34948-34957.
2001
The Absence of Activator Protein 1-dependent Gene Expression in THP-1 Macrophages Stimulated with Phorbol Esters Is Due to Lack of p38 Mitogen-activated Protein Kinase Activation
. 276:33826-33832.
2001
Characterization of Selected Strains of Pneumococcal Surface Protein A
. 276:33121-33128.
2001
Oncogenic Ras Represses Transforming Growth Factor-β/Smad Signaling by Degrading Tumor Suppressor Smad4
. 276:29531-29537.
2001
L-Arginine Chlorination Products Inhibit Endothelial Nitric Oxide Production
. 276:27159-27165.
2001
Dimerization of Resistin and Resistin-like Molecules is Determined by a Single Cysteine
. 276:25970-25973.
2001
Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase
. 276:26486-26491.
2001
Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis
. 276:24565-24573.
2001
ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors. Characterizing ARL1-binding proteins
. 276:22826-22837.
2001
An Essential Role for Mad Homology Domain 1 in the Association of Smad3 with Histone Deacetylase Activity
. 276:22595-22603.
2001
Characterization of a novel type of human microsomal 3α -hydroxysteroid dehydrogenase. Unique tissue distribution and catalytic properties
. 276:22278-22286.
2001
Demonstration of Direct Effects of Growth Hormone on Neonatal Cardiomyocytes
. 276:22892-22900.
2001
Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins
. 276:18757-18764.
2001
Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling
. 276:18908-18914.
2001
Agonist-regulated Interaction between α
2
-Adrenergic Receptors and Spinophilin
. 276:15003-15008.
2001
Phosphorylation of Protein Phosphatase Inhibitor-1 by Cdk5
. 276:14490-14497.
2001
Studies of Insulin Secretory Responses and of Arachidonic Acid Incorporation into Phospholipids of Stably Transfected Insulinoma Cells That Overexpress Group VIA Phospholipase A
2
(iPLA
2
β) Indicate a Signaling Rather Than a Housekeeping Role for iPLA
2
β
. 276:13198-13208.
2001
The Angiotensin II-dependent Nuclear Translocation of Stat1 is Mediated by the Jak2 Protein Motif
231
YRFRR
. 276:10556-10563.
2001
Transcriptional mechanisms of bone morphogenetic protein-induced osteoprotegrin gene expression.
. 276:10119-10125.
2001
Expression and Regulation of Normal and Polymorphic Epithelial Sodium Channel by Human Lymphocytes
. 276:8557-8566.
2001
Cystic Fibrosis Transmembrane Conductance Regulator Facilitates ATP Release by Stimulating a Separate ATP Release Channel for Autocrine Control of Cell Volume Regulation
. 276:6621-6630.
2001
Structural Transformations Accompanying the Assembly of Bacteriophage P22 Portal Protein Rings in Vitro
. 276:6779-6788.
2001
Human Homolog of the MutY Repair Protein (hMYH) Physically Interacts with Proteins Involved in Long Patch DNA Base Excision Repair
. 276:5547-5555.
2001
The p115-interactive Proteins GM130 and Giantin Participate in Endoplasmic Reticulum-Golgi Traffic
. 276:2693-2700.
2001
Molecular cloning and characterization of a novel regulator of G-protein signaling from mouse hematopoietic stem cells
. 276:915-923.
2001
Indirubins inhibit glycogen synthase kinase-3β and CDK5/P25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
. 276:251-260.
2001
Smad7-dependent regulation of heme oxygenase-1 by transforming growth factor-β in human renal epithelial cells
. 275:40904-40909.
2000
Regulation of plasminogen activator inhibitor-1 expression by transforming growth factor-β-induced physical and functional interactions between Smads and Sp1
. 275:40014-40019.
2000
Identification and characterization of two G protein-coupled receptors for neuropeptide FF.
. 275:39324-39331.
2000
Reaction of S-nitrosoglutathione with the heme group of deoxyhemoglobin
. 275:36562-36567.
2000
Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin
. 275:36358-36368.
2000
Transforming growth factor-beta up-regulates the beta 5 integrin subunit expression via Sp1 and Smad signaling.
. 275:36400-36406.
2000
Characterization of the repressor function of the nuclear orphan receptor retinoid receptor-related testis-associated receptor/germ cell nuclear factor
. 275:35077-35085.
2000
Integrin activation and focal complex formation in cardiac hypertrophy
. 275:35624-35630.
2000
A constitutive active MEK → ERK pathway negatively regulates NF-κB-dependent gene expression by modulating TATA-binding protein phosphorylation
. 275:27858-27864.
2000
A rat kidney-specific calcium transporter in the distal nephron
. 275:28186-28194.
2000
The cytosolic termini of the β- and γ-ENaC subunits are involved in the functional interactions between cystic fibrosis transmembrane conductance regulator and epithelial sodium channel
. 275:27947-27956.
2000
Biosynthesis of type 3 capsular polysaccharide in Streptococcus pneumoniae: Enzymatic chain release by an abortive translocation process
. 275:25972-25978.
2000
Erratum: Design and analysis of an engineered human interleukin-10 monomer (Journal of Biological Chemistry (2000) 275 (13552-13557))
. 275:25054.
2000
Involvement of STAT-1 and Ets family members interferon-γ induction of CD40 transcription in microglia/macrophages
. 275:23674-23684.
2000
Phosphorylation of human glutamine:fructose-6-phosphate amidotransferase by cAMP-dependent protein kinase at serine 205 blocks the enzyme activity
. 275:21981-21987.
2000
Concentration-dependent effects of nitric oxide on mitochondrial permeability transition and cytochrome c release
. 275:20474-20479.
2000
Binding and cross-linking studies show that scavenger receptor BI interacts with multiple sites in apolipoprotein A-I and identify the class A amphipathic α-helix as a recognition motif
. 275:18897-18904.
2000
Cyclic nucleotide-gated channels mediate membrane depolarization following activation of store-operated calcium entry in endothelial cells
. 275:18887-18896.
2000
Electrospray ionization/mass spectrometric analyses of human promonocytic U937 cell glycerolipids and evidence that differentiation is associated with membrane lipid composition changes that facilitate phospholipase A
2
activation
. 275:16579-16589.
2000
Biochemical structural analysis of the lantibiotic mutacin II
. 275:15845-15850.
2000
Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate
. 275:15246-15253.
2000
The prodomain of caspase-1 enhances Fas-mediated apoptosis through facilitation of caspase-8 activation
. 275:14248-14254.
2000
Design and analysis of an engineered human interleukin-10 monomer
. 275:13552-13557.
2000
Nitric oxide reaction with lipid peroxyl radicals spares α-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/α-tocopherol than α-tocopherol/ascorbate
. 275:10812-10818.
2000
Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus
. 275:10196-10201.
2000
Sweet Tooth, a novel receptor protein-tyrosine kinase with C-type lectin-like extracellular domains
. 275:10323-10330.
2000
Sp1/Sp3 and PU.1 differentially regulate beta(5) integrin gene expression in macrophages and osteoblasts.
. 275:8331-8340.
2000
HeLa cells are phenotypically limiting in cyclin E/CDK2 for efficient human papillomavirus DNA replication
. 275:6167-6174.
2000
Loss of the major isoform of phosphoglucomutase results in altered calcium homeostasis in Saccharomyces cerevisiae
. 275:5431-5440.
2000
Mechanism of type 3 capsular polysaccharide synthesis in Streptococcus pneumoniae
. 275:3907-3914.
2000
De novo design of peptides targeted to the EF hands of calmodulin
. 275:2676-2685.
2000
Peptide inhibition of constitutively activated epithelial Na
+
channels expressed in Xenopus oocytes
. 274:37693-37704.
1999
Regulation of epithelial Na
+
channels by actin in planar lipid bilayers and in the Xenopus oocyte expression system
. 274:37845-37854.
1999
DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells
. 274:37450-37454.
1999
Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts
. 274:36015-86024.
1999
The adenosine transporter of Toxoplasma gondii. Identification by insertional mutagenesis, cloning, and recombinant expression
. 274:35255-35261.
1999
Transcriptional regulation of Fas gene expression by GA-binding protein and AP-1 in T cell antigen receptor · CD3 complex-stimulated T cells
. 274:35203-35210.
1999
Yeast SMF1 mediates H
+
-coupled iron uptake with concomitant uncoupled cation currents
. 274:35089-35094.
1999
A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure
. 273:31731-31737.
1999
Molecular and functional characterization of a calcium-sensitive chloride channel from mouse lung
. 273:32096-32101.
1999
Mutations in the yeast Hsp40 chaperone protein Ydj1 cause defects in Axl1 biogenesis and pro-a-factor processing
. 274:34396-34402.
1999
Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2αB/core binding factor α2
. 274:33580-33586.
1999
A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn
. 274:33131-33142.
1999
Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH- induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization
. 274:33072-33084.
1999
A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein
. 274:31755-31758.
1999
Casein kinase II activity is required for transferrin receptor endocytosis
. 274:30550-30556.
1999
The p38 mitogen-activated protein kinase is required for NF-κB- dependent gene expression. The role of TATA-binding protein (TBP)
. 274:30858-30863.
1999
The cytoplasmic domain of human FcγRIa alters the functional properties of the FcγRI·γ-chain receptor complex
. 274:30328-30333.
1999
Regulation of cyclooxygenase-2 by interferon γ and transforming growth factor α in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases
. 274:29138-29148.
1999
The transcription factors Sp1, Sp3, and AP-2 are required for constitutive matrix metalloproteinase-2 gene expression in astroglioma cells
. 274:29130-29137.
1999
Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α
1
β
1
integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913))
. 274:28836.
1999
Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus Cna MSCRAMM. (vol 274, pg 24906, 1999)
. 274:28836-28836.
1999
The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization
. 274:27553-27561.
1999
Regulation of AMP deaminase by phosphoinositides
. 274:25701-25707.
1999
Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α
1
β
1
integrin and Staphylococcus aureus Cna MSCRAMM
. 274:24906-24913.
1999
An analysis of the binding of repressor protein ModE to modABCD (molybdate transport) operator/promoter DNA of Escherichia coli
. 274:24308-24315.
1999
The photoreactivity of the retinal age pigment lipofuscin
. 274:23828-23832.
1999
Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption
. 274:22739-22746.
1999
Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase
. 274:21276-21284.
1999
Interaction of syntaxins with the amiloride-sensitive epithelial sodium channel
. 274:20812-80817.
1999
15-Lipoxygenase catalytically consumes nitric oxide and impairs activation of guanylate cyclase
. 274:20083-20091.
1999
Analysis of tyro sine phosphorylation-dependent interactions between stimulatory effector proteins and the B cell co-receptor CD22
. 274:18769-18776.
1999
Human alveolar macrophages are markedly deficient in REF-1 and AP-1 DNA binding activity
. 274:18075-18080.
1999
Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation
. 274:15487-15492.
1999
An IgA-binding peptide derived from a streptococcal surface protein
. 274:14521-14524.
1999
An N-terminal region of Sp1 targets its proteasome-dependent degradation in vitro
. 274:15194-15202.
1999
The structure of human lipoprotein A-I. Evidence for the 'belt' model
. 274:14541-14544.
1999
Zinc content of Escherichia coli-expressed constitutive isoforms of nitric-oxide synthase. Enzymatic activity and effect of pterin
. 274:14537-14540.
1999
Studies of the role of group VI phospholipase A
2
in fatty acid incorporation, phospholipid remodeling, lysophosphatidylcholine generation, and secretagogue-induced arachidonic acid release in pancreatic islets and insulinoma cells
. 274:13915-13927.
1999
Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway
. 274:13434-13442.
1999
The activation sequence of thrombospondin-1 interacts with the latency- associated peptide to regulate activation of latent transforming growth factor-β
. 274:13586-13593.
1999
Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A
2
(iPLA
2
) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA
2
gene on chromosome 22q13.1
. 274:9607-9616.
1999
Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages: 7,8-dihydro-8-oxoguanine and 5- hydroxycytosine
. 274:8516-8523.
1999
The biochemical role of glutamine 188 in human galactose-1-phosphate uridyltransferase
. 274:6559-6566.
1999
Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae
. 274:5797-5809.
1999
Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion
. 274:5692-5700.
1999
The Golgi apparatus plays a significant role in the maintenance of Ca
2+
homeostasis in the vps33Δ vacuolar biogenesis mutant of saccharomyces cerevisiae
. 274:5939-5947.
1999
Binding of xanthine oxidase to vascular endothelium: Kinetic characterization and oxidative impairment of nitric oxide-dependent signaling
. 274:4985-4994.
1999
Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal
. 274:3602-3609.
1999
Regulation of the transglutaminase I gene. Identification of DNA elements involved in its transcriptional control in tracheobronchial epithelial cells
. 274:3887-3896.
1999
Cascades of mammalian caspase activation in the yeast Saccharomyces cerevisiae
. 274:3189-3198.
1999
Human papillomavirus DNA replication: Interactions between the viral E1 protein and two subunits of human DNA polymerase α/primase
. 274:2696-2705.
1999
Apolipoprotein-mediated plasma membrane microsolubilization: Role of lipid affinity and membrane penetration in the efflux of cellular cholesterol and phospholipid
. 274:2021-2028.
1999
Apical sorting of bovine enteropeptidase does not involve detergent- resistant association with sphingolipid-cholesterol rafts
. 274:1596-1605.
1999
Cloning of the murine beta5 integrin subunit promoter. Identification of a novel sequence mediating granulocyte-macrophage colony-stimulating factor-dependent repression of beta5 integrin gene transcription.
. 274:1366-1374.
1999
Identification of STRAP, a novel WD domain protein in transforming growth factor-β signaling
. 273:34671-34674.
1998
The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding
. 273:34799-34805.
1998
Molecular cloning, characterization, and dynamics of rat formiminotransferase cyclodeaminase, a Golgi-associated 58-kDa protein
. 273:33825-33834.
1998
Intragenic suppressors of mutant DNA topoisomerase I-induced lethality diminish enzyme binding of DNA
. 273:31519-31527.
1998
Human Hsp70 and Hsp40 chaperone proteins facilitate human papillomavirus-11 E1 protein binding to the origin and stimulate cell-free DNA replication
. 273:30704-30712.
1998
Multiple heparan sulfate chains are required for optimal syndecan-1 function
. 273:29965-29971.
1998
The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61β and a cytosolic, deglycosylated intermediary
. 273:29873-29878.
1998
Chronic nicotine treatment up-regulates human alpha3 beta2 but not alpha3 beta4 acetylcholine receptors stably transfected in human embryonic kidney cells.
. 273:28721-28732.
1998
High affinity hormone binding to the extracellular N-terminal exodomain of the follicle-stimulating hormone receptor is critically modulated by exoloop 3
. 273:28953-28958.
1998
Induction of topoisomerase I cleavage complexes by the vinyl chloride adduct 1,N
6
-ethenoadenine
. 273:27245-27249.
1998
Nitrosation of uric acid by peroxynitrite: Formation of a vasoactive nitric oxide donor
. 273:24491-24497.
1998
Heparan sulfate proteoglycans as adhesive and anti-invasive molecules: Syndecans and glypican have distinct functions
. 273:22825-22832.
1998
Structural requirements for major histocompatibility complex class II invariant chain endocytosis and lysosomal targeting
. 273:20644-20652.
1998
Regulation of casein kinase 2 by direct interaction with cell surface receptor CD5
. 273:19183-19189.
1998
Analysis of the structural requirements for lysosomal membrane targeting using transferrin receptor chimeras
. 273:14355-14362.
1998
Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C
. 273:12135-12139.
1998
Major histocompatibility class II-mediated signal transduction is regulated by the protein-tyrosine phosphatase CD45
. 273:11970-11979.
1998
Regulation of peroxisome proliferator-activated receptor α-induced transactivation by the nuclear orphan receptor TAK1/TR4
. 273:10948-10957.
1998
A phosphatidylinositol 3-kinase and phosphatidylinositol transfer protein act synergistically in formation of constitutive transport vesicles from the trans-Golgi network
. 273:10349-10354.
1998
Syndecan-4 proteoglycan cytoplasmic domain and phosphatidylinositol 4,5- bisphosphate coordinately regulate protein kinase C activity
. 273:10624-10629.
1998
RhoB is stabilized by transforming growth factor β and antagonizes transcriptional activation
. 273:9921-9926.
1998
Differential regulation of human neutrophil FcγRIIa (CD32) and FcγRIIIb (CD16)-induced Ca
2+
transients
. 273:8071-8079.
1998
Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I
. 273:8425-8433.
1998
A role for superoxide in protein kinase C activation and induction of long-term potentiation
. 273:4516-4522.
1998
Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling
. 273:2344-2354.
1998
Thrombospondin signaling of focal adhesion disassembly requires activation of phosphoinositide 3-kinase
. 273:1755-1763.
1998
Molecular cloning, sequence analysis, expression, and tissue distribution of suppressin, a novel suppressor of cell cycle entry
. 273:361-368.
1998
Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain
. 272:31293-31300.
1997
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
. 272:31427-31434.
1997
CUG repeats present in myotonin kinase RNA form metastable 'slippery' hairpins
. 272:31079-31085.
1997
The DNA cleavage reaction of DNA gyrase. Comparison of stable ternary complexes formed with enoxacin and CcdB protein.
. 272:27202-27209.
1997
Identification of an amiloride binding domain within the α-subunit of the epithelial Na
+
channel
. 272:21075-21083.
1997
Interleukin-1 reduces the glycolytic utilization of glucose by pancreatic islets and reduces glucokinase mRNA content and protein synthesis by a nitric oxide-dependent mechanism
. 272:17827-17835.
1997
Epidermal growth factor induces CD44 gene expression through a novel regulatory element in mouse fibroblasts
. 272:14139-14146.
1997
Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death
. 272:12801-12808.
1997
Camptothecin sensitivity is mediated by the pleiotropic drug resistance network in yeast
. 272:12091-12099.
1997
Pancreatic islets express a Ca
2+
-independent phospholipase A
2
enzyme that contains a repeated structural motif homologous to the integral membrane protein binding domain of ankyrin
. 272:11118-11127.
1997
Characterization of the response element and DNA binding properties of the nuclear orphan receptor germ cell nuclear factor/retinoid receptor- related testis-associated receptor
. 272:10565-10572.
1997
The globin-based free radical of ferryl hemoglobin is detected in normal human blood
. 272:7114-7121.
1997
A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A
. 272:6561-6566.
1997
Hepatocyte growth factor alters the polarity of Madin-Darby canine kidney cell monolayers
. 272:3471-3477.
1997
'Oxidation inhibits substrate proteolysis by calpain I but not autolysis
. 272:2005-2012.
1997
Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation
. 271:30436-30441.
1996
Human immunodeficiency virus: Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complex
. 271:33231-33235.
1996
Topoisomerase II-etoposide interactions direct the formation of drug- induced enzyme-DNA cleavage complexes
. 271:29238-29244.
1996
Insulin-induced egr-1 and c-fos expression in 32D cells requires insulin receptor, Shc, and mitogen-activated protein kinase, but not insulin receptor substrate-1 and phosphatidylinositol 3-kinase activation.
. 271:30222-30226.
1996
Kinetic interconversion of rat and bovine homologs of the α subunit of an amiloride-sensitive Na
+
channel by C-terminal truncation of the bovine subunit
. 271:26602-26608.
1996
Identification and cloning of centaurin-α. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain
. 271:18859-18868.
1996
A 3' cis-acting element is involved in tumor necrosis factor-α gene expression in astrocytes
. 271:22383-22390.
1996
Functional reconstitution in situ of 5-hydroxytryptamine(2c) (5HT(2c)) receptors with α(q) and inverse agonism of 5HT(2c) receptor antagonists
. 271:22591-22597.
1996
The luteinizing hormone/chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals
. 271:19283-19287.
1996
Competition for a unique response element mediates retinoic acid inhibition of vitamin D3-stimulated transcription.
. 271:20650-20654.
1996
Regulation of epithelial sodium channels by short actin filaments
. 271:17704-17710.
1996
A novel Ca
2+
-binding protein, p22, is required for constitutive membrane traffic
. 271:10183-10187.
1996
Dissociation of cyclic inositol phosphohydrolase activity from annexin III
. 271:8295-8299.
1996
Exoloop 3 of the luteinizing hormone/choriogonadotropin receptor: Lys
583
is essential and irreplaceable for human choriogonadotropin (hCG)-dependent receptor activation but not for high affinity hCG binding
. 271:7301-7304.
1996
Distinct functional properties of Rab3A and Rab3B in PC12 neuroendocrine cells
. 271:6963-6971.
1996
Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.
. 271:5839-5843.
1996
α
1
-adrenergic receptor subtype mRNAs are differentially regulated by α
1
-Adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo: Repression of α
1B
and α
1D
but induction of α
1C
. 271:5839-5843.
1996
G-protein regulation of outwardly rectified epithelial chloride channels incorporated into planar bilayer membranes
. 271:4776-4780.
1996
Regulation of epithelial sodium channels by the cystic fibrosis transmembrane conductance regulator
. 271:4725-4732.
1996
Cyclic AMP and chloride-dependent regulation of the apical constitutive secretory pathway in colonic epithelial cells
. 271:4381-4387.
1996
Cloning and regulation of cornifin β, a new member of the cornifin/spr family: Suppression by retinoic acid receptor-selective retinoids
. 271:3737-3742.
1996
The role of cytosolic calcium in chronic adaptation to phosphate depletion in opossum kidney cells
. 271:3902-3906.
1996
Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism*
. 271:1029-1042.
1996
Triple-barrel organization of ENaC, a cloned epithelial Na
+
channel
. 271:807-816.
1996
Erratum: The luteinizing hormone-chorionic gonadotropin receptor has distinct transmembrane conductors for cAMP and inositol phosphate signals (Journal of Biological Chemistry (1996) 271 (19283-19287))
. 271:26444.
1996
Metabolism of serotonin to n-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture
. 271:12281-12286.
1996
Cloning of an epithelial chloride channel from bovine trachea
. 270:31016-31026.
1995
The effects of brefeldin A on the glucose transport system in rat adipocytes: Implications regarding the intracellular locus of insulin-sensitive Glut4
. 270:30199-30204.
1995
The human gp39 promoter: Two distinct nuclear factors of activated T cell protein-binding elements contribute independently to transcriptional activation
. 270:29624-29627.
1995
Interaction between cystic fibrosis transmembrane conductance regulator and outwardly rectified chloride channels
. 270:29194-29200.
1995
Insulin-induced egr-1 expression in Chinese hamster ovary cells is insulin receptor and insulin receptor substrate-1 phosphorylation-independent. Evidence of an alternative signal transduction pathway.
. 270:26632-26638.
1995
Pancreatic islet cells express a family of inwardly rectifying K
+
channel subunits which interact to form G-protein-activated channels
. 270:26086-26091.
1995
The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor β
c
chain
. 270:13814-13818.
1995
Heparan sulfate-mediated cell aggregation: Syndecans-1 and -4 mediate intercellular adhesion following their transfection into human B lymphoid cells
. 270:5077-5083.
1995
A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons
. 270:6141-6148.
1995
Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species
. 270:18825-18830.
1995
Calculation of absolute metabolic flux and the elucidation of the pathways of glutamate labeling in perfused rat heart by
13
C NMR spectroscopy and nonlinear least squares analysis
. 270:7999-8008.
1995
Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase
. 270:17437-17441.
1995
Effect of the arrangement of tandem repeating units of class A amphipathic α-helixes on lipid interaction
. 270:1602-1611.
1995
Effect of the cholesterol content of reconstituted LpA-I on lecithin:cholesterol acyltransferase activity
. 270:5151-5157.
1995
Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids
. 270:6022-6029.
1995
High hydrostatic pressure induces the dissociation of cpn60 tetradecamers and reveals a plasticity of the monomers
. 270:2061-2066.
1995
Identification and characterization of a novel squamous cell-associated gene related to PMP22
. 270:28910-28916.
1995
Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized
. 270:18543-18550.
1995
Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
. 270:14776-14785.
1995
Regulation of transforming growth factor-β activation by discrete sequences of thrombospondin 1
. 270:7304-7310.
1995
Signal transduction by a CD16/CD7/Jak2 fusion protein
. 270:18420-18427.
1995
The Ca
2+
dependence of human Fcγ receptor-initiated phagocytosis
. 270:22301-22307.
1995
The Golgi association of endothelial nitric oxide synthase is necessary for the efficient synthesis of nitric oxide
. 270:17641-17644.
1995
The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication
. 270:27283-27291.
1995
Ganglioside G(D1α) in cerebellar Purkinje cells: Its specific absence in mouse mutants with Purkinje cell abnormality and altered immunoreactivity in response tc conjunctive stimuli causing long term desensitization
. 269:32418-32425.
1994
Autonomously active protein kinase C in the maintenance phase of N- methyl-D-aspartate receptor-independent long term potentiation
. 269:27958-27963.
1994
Phosphorylation and activation of a bovine tracheal anion channel by Ca
2+
/calmodulin-dependent protein kinase II
. 269:26642-26649.
1994
Hemolytically inactive C4B complement allotype caused by a proline to leucine mutation in the C5-binding site
. 269:27727-27731.
1994
The glycosylation of phosphoglucomutase is modulated by carbon source and heat shock in Saccharomyces cerevisiae
. 269:27143-27148.
1994
The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-β
. 269:26783-26788.
1994
Thrombospondin binds and activates the small and large forms of latent transforming growth factor-β in a chemically defined system
. 269:26775-26782.
1994
Binding of apolipoprotein A-I model peptides to lipid bilayers. Measurement of binding isotherms and peptide-lipid headgroup interactions
. 269:23904-23910.
1994
Cell-free replication of the human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts
. 269:24058-24065.
1994
The influence of apolipoprotein structure on the efflux of cellular free cholesterol to high density lipoprotein
. 269:22975-22982.
1994
Retinoid-resistant estrogen receptor-negative human breast carcinoma cells transfected with retinoic acid receptor-α acquire sensitivity to growth inhibition by retinoids
. 269:21440-21447.
1994
Expression of syndecan-1 inhibits cell invasion into type I collagen
. 269:20013-20019.
1994
G-proteins modulate amiloride-sensitive sodium channels
. 269:17780-17783.
1994
Nucleotide-specific transcriptional pausing in the pyrBI leader region of Escherichia coli K-12.
. 269:18185-18191.
1994
Premature translation termination mutations are efficiently suppressed in a highly conserved region of yeast Ste6p, a member of the ATP-binding cassette (ABC) transporter family
. 269:17802-17808.
1994
Characterization of the mitochondrial binding and import properties of purified yeast F
1
-ATPase β subunit precursor. Import requires external ATP
. 269:7192-7200.
1994
Mechanism and subcellular localization of secretory IgM polymer assembly
. 269:17338-17348.
1994
Multiple components of the B cell antigen receptor complex associate with the protein tyrosine phosphatase, CD45
. 269:17238-17244.
1994
Cytokines and HIV envelope glycoprotein gp120 stimulate Na
+
/H
+
exchange in astrocytes
. 269:13811-13816.
1994
Fine structure of heparan sulfate regulates syndecan-1 function and cell behavior
. 269:13100-13106.
1994
Molecular characterization of protein Sir, a streptococcal cell surface protein that binds both immunoglobulin A and immunoglobulin G
. 269:13458-13464.
1994
A peptide encoding the c-Jun δ domain inhibits the activity of a c-Jun amino-terminal protein kinase
. 269:11186-11191.
1994
Matrix effects suggest an important influence of DNA-polyacrylamide interactions on the electrophoretic mobility of DNA
. 269:10156-10162.
1994
Control of growth regulatory and differentiation-specific genes in human epidermal keratinocytes by interferon γ: Antagonism by retinoic acid and transforming growth factor β1
. 269:2016-2022.
1994
Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N- acyltransferase
. 269:19375-19379.
1994
Interactions of synthetic peptide analogs of the class A amphipathic helix with lipids. Evidence for the snorkel hypothesis
. 269:7185-7191.
1994
Molecular determinants of bioactivity of the Saccharomyces cerevisiae lipopeptide mating pheromone
. 269:19817-19825.
1994
Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives
. 269:26066-26075.
1994
Repression of transforming growth factor β1 promoter by the adenovirus oncogene E1A. Identification of a unique GC-rich sequence as a target for E1A repression
. 269:25392-25399.
1994
Structure and expression of the human gene for the α subunit of prolyl 4- hydroxylase. The two alternatively spliced types of mRNA correspond to two homologous exons the sequences of which are expressed in a variety of tissues
. 269:27847-27854.
1994
Xylosyl transfer to an endogenous renal acceptor. Characteristics of the reaction and properties of the product
. 269:11503-11508.
1994
Xylosyl transfer to an endogenous renal acceptor. Purification of the transferase and the acceptor and their identification as glycogenin
. 269:11509-11513.
1994
Use of transgenic mice to study regulation of gene expression in the parietal cell lineage of gastric units
. 268:26559-26570.
1993
A mitochondrial porin cDNA predicts the existence of multiple human porins
. 268:12143-12149.
1993
Arachidonic acid release from aortic smooth muscle cells induced by [Arg
8
]vasopressin is largely mediated by calcium-independent phospholipase A
2
. 268:20713-20716.
1993
Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity
. 268:11176-11187.
1993
Cytosolic domain of the human immunodeficiency virus envelope glycoproteins binds to calmodulin and inhibits calmodulin-regulated proteins
. 268:22895-22899.
1993
Heparin-binding peptides from thrombospondins 1 and 2 contain focal adhesion-labilizing activity
. 268:26784-26789.
1993
Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors
. 268:19312-19320.
1993
Mechanisms of camptothecin resistance in yeast DNA topoisomerase I mutants
. 268:22322-22330.
1993
Phosphoglucomutase in Saccharomyces cerevisiae is a cytoplasmic glycoprotein and the acceptor for a Glc-phosphotransferase
. 268:8341-8349.
1993
Reciprocal effects of apolipoprotein and lytic peptide analogs on membranes. Cross-sectional molecular shapes of amphipathic α helixes control membrane stability
. 268:22112-22118.
1993
YTRF is the conserved internalization signal of the transferrin receptor, and a second YTRF signal at position 31-34 enhances endocytosis
. 268:21686-21692.
1993
Erratum: Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes (The Journal of Biological Chemistry (1992) 267 (18498-18504))
. 267:26200.
1992
Functional reconstitution of a chloride channel protein from bovine trachea
. 267:20630-20637.
1992
Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes
. 267:18498-18504.
1992
INVITRO ISOPRENYLATION AND MEMBRANE ASSOCIATION OF MOUSE ROD PHOTORECEPTOR CGMP PHOSPHODIESTERASE ALPHA-SUBUNIT AND BETA-SUBUNIT EXPRESSED IN BACTERIA
. 267:8458-8463.
1992
Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel
. 267:6257-6262.
1992
Crystal structure of recombinant human interleukin-4
. 267:20371-20376.
1992
Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells
. 267:18002-18007.
1992
Erratum: Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production (Journal of Biological Chemistry (1992) 267 (13656-13660))
. 267:19752.
1992
In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase α and β subunits expressed in bacteria
. 267:8458-8463.
1992
Inhibition of protein phosphatases blocks myogenesis by first altering MyoD binding activity
. 267:15140-15145.
1992
Intermolecular triplex formation distorts the DNA duplex in the regulatory region of human papillomavirus type-11
. 267:5488-5494.
1992
Membrane interactions of synthetic peptides corresponding to amphipathic helical segments of the human immunodeficiency virus type-1 envelope glycoprotein
. 267:7121-7127.
1992
Molecular cloning, sequencing, deletion, and overexpression of a methionine aminopeptidase gene from Saccharomyces cerevisiae
. 267:8007-8011.
1992
Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production
. 267:13656-13660.
1992
Photoaffinity labeling and characterization of isolated inositol 1,3,4,5- tetrakisphosphate- and inositol hexakisphosphate-binding proteins
. 267:9071-9079.
1992
Purification and characterization of heterodimeric human immunodeficiency virus type 1 (HIV-1) reverse transcriptase produced by in vitro processing of p66 with recombinant HIV-1 protease
. 267:14227-14232.
1992
Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene product
. 267:6455-6458.
1992
Synergistic interaction between the probucol phenoxyl radical and ascorbic acid in inhibiting the oxidation of low density lipoprotein
. 267:6789-6795.
1992
Interferon-γ-induced astrocyte class II major histocompatibility complex gene expression is associated with both protein kinase C activation and Na
+
entry
. 266:18119-18126.
1991
Complete structure of the human gene for 92-kDa type IV collagenase. Divergent regulation of expression for the 92- and 72-kilodalton enzyme genes in HT-1080 cells
. 266:16485-16490.
1991
Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts
. 266:16376-16379.
1991
Regulation of c-jun expression and AP-1 enhancer activity by granulocyte-macrophage colony-stimulating factor
. 266:5670-5675.
1991
Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells
. 266:11262-11269.
1991
Purification and characterization of bile acid-CoA:amino acid N-acyltransferase from human liver
. 266:10227-10233.
1991
Topoisomerase mutants and physiological conditions control supercoiling and Z-DNA formation in vivo
. 266:2576-2581.
1991
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases α, β, and γ by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine, and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs
. 266:1754-1762.
1991
Structure of the human laminin B2 chain gene reveals extensive divergence from the laminin B1 chain gene
. 266:221-228.
1991
Mouse opsin. Gene structure and molecular basis of multiple transcripts
. 265:20563-20569.
1990
Purification and characterization of a methionine aminopeptidase from Saccharomyces cerevisiae
. 265:19892-19897.
1990
Thermodynamics of the binding of human apolipoprotein A-I to dimyristoylphosphatidylglycerol
. 265:20829-20832.
1990
Nuclear magnetic resonance and molecular modeling studies on O-β-D-galactopyranosyl-(1→4)-O-β-D-xylopyranosyl-(1→0)-L-serine, a carbohydrate-protein linkage region fragment from connective tissue proteoglycans
. 265:18256-18262.
1990
Characterization of transcriptional initiation from promoters P1 and P2 of the pyrBI operon of Escherichia coli K12.
. 265:19091-19099.
1990
Structure of the human laminin B1 chain gene
. 265:15611-15616.
1990
Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 Å resolution
. 265:14016-14022.
1990
Compartmentalization of mammalian proteins produced in Escherichia coli
. 265:13066-13073.
1990
Nuclear magnetic resonance investigation of the interaction with phospholipid of an amphipathic α-helix-forming peptide of the apolipoprotein class
. 265:12217-12223.
1990
Model peptides reveal specificity of N(α)-acetyltransferase from Saccharomyces cerevisiae
. 265:11576-11580.
1990
Regulation of transglutaminase Type II by transforming growth factor-β1 in normal and transformed human epidermal keratinocytes
. 265:11098-11104.
1990
Structure of the human type IV collagenase gene
. 265:11077-11082.
1990
A glucose-repressible gene encodes acetyl-CoA hydrolase from Saccharomyces cerevisiae
. 265:7413-7418.
1990
An anti-sense c-erbA clone inhibits thyroid hormone-induced expression from the α-myosin heavy chain promoter
. 265:6489-6493.
1990
Identification of methionine N(α)-acetyltransferase from Saccharomyces cerevisiae
. 265:3603-3606.
1990
Identification and sequence analysis of four complement factor H-related transcripts in mouse liver
. 265:3193-3201.
1990
Isolation, purification, and partial characterization of suppressin, a novel inhibitor of cell proliferation
. 265:158-165.
1990
7-Azidoactinomycin D: A novel probe for examining actinomycin D-DNA interactions
. 264:7262-7266.
1989
Biochemical characterization of the η chain of the T-cell receptor. A unique subunit related to ξ
. 264:14812-14817.
1989
Cloning and sequence analysis of a rat liver cDNA encoding acyl-peptide hydrolase
. 264:8892-8899.
1989
Evidence for an imipramine-sensitive serotonin transporter in human placental brush-border membrane
. 264:2195-2198.
1989
Inhibition of the high affinity Fc receptor (Fc(γ)RI) on human monocytes by porphyrin photosensitization is highly specific and mediated by the generation of superoxide radicals
. 264:11407-11413.
1989
Molecular cloning and sequencing of a cDNA encoding N(α)-acetyltransferase from Saccharomyces cerevisiae
. 264:12339-12343.
1989
Molecular cloning and sequencing of genomic DNA encoding aminopeptidase I from Saccharomyces cerevisiae
. 264:6979-6983.
1989
Phorbol ester or epidermal growth factor (EGF) stimulates the concurrent accumulation of mRNA for the EGF receptor and its ligand transforming growth factor-α in a breast cancer cell line
. 264:4021-4027.
1989
Properties of lipid complexes with amphipathic helix-forming peptides. Role of distribution of peptide charges
. 264:4628-4635.
1989
Substitutions engineered by chemical synthesis at three conserved sites in mitochondrial cytochrome c. Thermodynamic and functional consequences
. 264:15199-15209.
1989
Supercoiling and integration host factor change the DNA conformation and alter the flow of convergent transcription in phage Mu.
. 264:3035-3042.
1989
Synthetic amphipathic peptides resembling apolipoproteins stimulate the release of human placental lactogen
. 264:9215-9219.
1989
Transforming growth factor-α in the mammalian brain. Immunohistochemical detection in neurons and characterization of its mRNA
. 264:3880-3883.
1989
Chinese hamster ovary cell mutants deficient in an anion exchanger functionally similar to the erythroid band 3
. 263:18607-18613.
1988
A proton gradient is the driving force for uphill transport of lactate in human placental brush-border membrane vesicles
. 263:13823-13830.
1988
Altered metabolism of thrombospondin by Chinese hamster ovary cells defective in glycosaminoglycan synthesis
. 263:6400-6406.
1988
Characterization of the human gene for a polypeptide that acts both as the β subunit of prolyl 4-hydroxylase and as protein disulfide isomerase
. 263:16218-16224.
1988
Chemical modification of bovine prothrombin fragment 1 in the presence of Tb
3+
ions. Sequence studies on 3-γ-MGlu-fragment 1
. 263:8150-8156.
1988
Identification of a promoter region in the CGβ gene cluster
. 263:7322-7329.
1988
Interactions of chloride and amiloride with the renal Na
+
/H
+
antiporter
. 263:7216-7221.
1988
Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c
. 263:8625-8634.
1988
Phospholipid bindng properties of bovine prothrombin peptide residues 1-45
. 263:14216-14223.
1988
Purification and characterization of an N alpha-acetyltransferase from Saccharomyces cerevisiae.
. 263:14948-14955.
1988
Structure of the murine complement factor H gene
. 263:16720-16724.
1988
Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type β transforming growth factor
. 263:13916-13921.
1988
Uridine phosphorylase from Schistosoma mansoni
. 263:6081-6086.
1988
Increase in cholesterol sulfotransferase activity during in vitro squamous differentiation of rabbit tracheal epithelial cells and its inhibition by retinoic acid
. 262:13069-13074.
1987
Inhibition of chondroitin and heparan sulfate biosynthesis in Chinese hamster ovary cell mutants defective in galactosyltransferase I.
. 262:12189-12195.
1987
Acyl-peptide hydrolase from rat liver. Characterization of enzyme reaction.
. 262:11435-11445.
1987
Nucleotide sequence and characterization of the pyrF operon of Escherichia coli K12.
. 262:10239-10245.
1987
Studies of synthetic peptide analogs of the amphipathic helix. Effect of charge distribution, hydrophobicity, and secondary structure on lipid association and lecithin:cholesterol acyltransferase activation.
. 262:9389-9396.
1987
Isolation, characterization, and biosynthesis of a phosphorylated glycoprotein from rat bone.
. 262:2900-2907.
1987
Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance
. 262:189-197.
1987
Reactive sulfhydryl groups of α
39
, a guanine nucleotide-binding protein from brain. Location and function
. 262:4501-4507.
1987
Shunting of insulin from a retroendocytotic pathway to a degradative pathway by sodium vanadate
. 262:12005-12012.
1987
Accumulation of cholesterol 3-sulfate during in vitro squamous differentiation of rabbit tracheal epithelial cells and its regulation by retinoids
. 261:13898-13904.
1986
Characterization of a regulatory region of the steroid 21-hydroxylase gene
. 261:15353.
1986
Characterization of transglutaminase activity in rabbit tracheal epithelial cells. Regulation by retinoids
. 261:15097-15101.
1986
Positive and negative regulation of the Mu operator by Mu repressor and Escherichia coli integration host factor
. 261:3744-3752.
1986
Sulfate transport-deficient mutants of Chinese hamster ovary cells. Sulfation of glycosaminoglycans dependent on cysteine
. 261:15725-15733.
1986
Surface receptor-mediated activation of adenylate cyclase in dictyostelium. Regulation by guanine nucleotides in wild-type cells and aggregation deficient mutants
. 261:15121-15125.
1986
Cleavage of bovine skin type III collagen by proteolytic enzymes. Relative resistance of the fibrillar form
. 260:16411-16417.
1985
Intrahepatic assembly of very low density lipoproteins. Varied synthetic response of individual apolipoproteins to fasting
. 260:14137-14144.
1985
Purification and characterization of the human liver cytochromes P-450 involved in debrisoquine 4-hydroxylation and phenacetin O-deethylation, two prototypes for genetic polymorphism in oxidative drug metabolism
. 260:9057-9067.
1985
Studies of synthetic peptide analogs of the amphiphatic helix. Correlation of structure with function
. 260:10256-10262.
1985
Studies of synthetic peptide analogs of the amphiphatic helix. Structure of complexes with dimyristoyl phosphatidylcholine
. 260:10248-10255.
1985
Characterization of distinct tyrosine-specific protein kinases in B and T lymphocytes
. 260:4351-4356.
1985
Biochemical characterization of mucous glycoproteins synthesized and secreted by hamster tracheal epithelial cells in primary culture
. 260:4021-4027.
1985
Identification and cyclic AMP-induced modification of the cyclic AMP receptor in Dictyostelium discoideum
. 260:1757-1764.
1985
The role of enzyme sequestration in the regulation of the adenylate cyclase of Dictyostelium discoideum
. 260:3613-3616.
1985
Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum
. 259:12318-12321.
1984
Transfer of cholesterol from its site of synthesis to the plasma membrane
. 259:14624-14630.
1984
The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct
. 259:8202-8209.
1984
Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action
. 259:6376-6384.
1984
The use of monoclonal antibodies to fragments of chicken type IV collagen in structural and localization studies
. 258:5794-5797.
1983
Studies of synthetic peptide analogs of the amphipathic helix. Competitive displacement of exchangeable apolipoproteins from native lipoproteins
. 258:2290-2295.
1983
Asymmetrical distributions of the Na
+
/H
+
antiporter in the renal proximal tubule epithelial cell
. 258:13513-13516.
1983
Isolation and characterization of human erythrocyte insulin receptors
. 258:5021-5026.
1983
Mixed type inhibition of the renal Na
+
/H
+
antiporter by the Li
+
and amiloride. Evidence for a modifier site
. 258:9710-9716.
1983
Intrahepatic assembly of very low density lipoproteins. Effect of fatty acids on triacylglycerol and apolipoprotein synthesis
. 257:10908-10913.
1982
Partial characterization of insulin receptors from rat myocytes
. 257:11128-11134.
1982
Purification and Macromolecular Properties of a Sialic-Acid Specific Lectin from Limax Flavus
. 257:7574-7580.
1982
A unique "mini" pepsinogen isolated from bullfrog esophageal glands.
. 257:795-798.
1982
Structural domains of vesicular stomatitis virus. A study by differential scanning calorimetry, thermal gel analysis, and thermal electron microscopy.
. 257:12-15.
1982
Does simian virus 40 T antigen unwind DNA?
. 256:10156-10160.
1981
Regional synthesis of monohydroxy eicosanoids by the kidney
. 256:10221-10223.
1981
Proton gradients in renal cortex brush-border membrane vesicles. Demonstration of a rheogenic proton flux with acridine orange.
. 256:11663-11666.
1981
Alignment of the peptides derived from acid-catalyzed cleavage of an aspartylprolyl bond in the major internal structural polypeptide of avian retroviruses
. 255:6962-6965.
1980
Polydispersity of rat mast cell heparin. Implications for proteoglycan assembly
. 255:11753-11758.
1980
Structural and functional properties of cytochrome c oxidases isolated from sharks.
. 255:2722-2728.
1980
Pseudouridylation of tRNAs and its role in regulation in Salmonella typhimurium.
. 254:5111-5119.
1979
Interaction of the chiral pyruvate analog, 2-keto-3-bromobutyrate, with pyruvate lyases. 2-Keto-3-deoxygluconate-6-phosphate aldolase of Pseudomonas putida
. 254:5862-5865.
1979
Triacylglycerol synthesis in isolated fat cells. Evidence that the sn glycerol 3 phosphate and dihydroxyacetone phosphate acyltransferase activities are dual catalytic functions of a single microsomal enzyme
. 251:5738-5744.
1976
Characterization of gastric mucosal membranes. VIII. The localization of peptides by iodination and phosphorylation
. 250:4802-4809.
1975
Enzymatic reduction of nicotinamide adenine dinucleotide phosphate induced by radiolysis
. 250:716-719.
1975
Effects of colicin K on a mutant of Escherichia coli deficient in Ca
2+
,Mg
2+
activated adenosine triphosphatase
. 249:6138-6143.
1974
Isolation and characterization of the immune macroglobulin from the paddlefish, Polyodon spathula.
. 246:6760-6769.
1971
Physical and chemical characterization of an oyster hemagglutinin.
. 244:4128-4135.
1969
Mucopolysaccharide sulfation in chick embryo cartilage. II. Characterization of the endogenous acceptor.
. 242:4956-4962.
1967
Mucopolysaccharide sulfation in chick embryo cartilage. I. Properties of the sulfation system.
. 242:1685-1689.
1967
Studies on antigen conformation during antibody purification.
. 238:1362-1366.
1963
Identity
International Standard Serial Number (issn)
0021-9258
Electronic International Standard Serial Number (eissn)
1083-351X