Genes and Development

Journal

Publication Venue For

  • Role of 53BP1 in end protection and DNA synthesis at DNA breaks.  35:1356-1368. 2021
  • Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2.  31:1243-1256. 2017
  • The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.  30:2551-2564. 2016
  • Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers.  29:2219-2224. 2015
  • Sequential replication-coupled destruction at G1/S ensures genome stability.  29:1734-1746. 2015
  • The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains.  29:1507-1523. 2015
  • The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration.  28:491-501. 2014
  • Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.  28:1085-1100. 2014
  • Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors.  27:2221-2226. 2013
  • USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing.  27:1581-1595. 2013
  • miR-26a is required for skeletal muscle differentiation and regeneration in mice.  26:2180-2191. 2012
  • Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity.  26:1247-1262. 2012
  • The effect of the intra-S-phase checkpoint on origins of replication in human cells.  25:621-633. 2011
  • miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis.  25:125-130. 2011
  • miR-451 protects against erythroid oxidant stress by repressing 14-3-3ζ.  24:1620-1633. 2010
  • RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs.  23:2753-2764. 2009
  • A novel class of small RNAs: tRNA-derived RNA fragments (tRFs).  23:2639-2649. 2009
  • A kiss of death - Proteasome-mediated membrane fusion and programmed cell death in plant defense against bacterial infection.  23:2449-2454. 2009
  • Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes.  23:181-194. 2009
  • Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression.  22:2980-2993. 2008
  • Parathyroid hormone signaling through low-density lipoprotein-related protein 6.  22:2968-2979. 2008
  • PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex.  22:2496-2506. 2008
  • Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity.  22:640-653. 2008
  • Mcm10 and And-1/CTF4 recruit DNA polymerase α to chromatin for initiation of DNA replication.  21:2288-2299. 2007
  • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.  21:1025-1030. 2007
  • The APC/C inhibitor, Emi1, is essential for prevention of rereplication.  21:184-194. 2007
  • Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells.  19:2827-2836. 2005
  • Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation.  19:2412-2417. 2005
  • Tomoregulin-1 (TMEFF1) inhibits nodal signaling through direct binding to the nodal coreceptor Cripto.  17:2624-2629. 2003
  • An essential role of Bmp4 in the atrioventricular septation of the mouse heart.  17:2362-2367. 2003
  • An intersubunit contact stimulating transcription initiation by E. coli RNA polymerase: Interaction of the α C-terminal domain and σ region 4.  17:1293-1307. 2003
  • Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association.  16:1518-1527. 2002
  • Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis.  16:235-244. 2002
  • The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development.  15:2010-2022. 2001
  • Down-regulation of TDT transcription in CD4+CD8+ thymocytes by Ikaros proteins in direct competition with an Ets activator.  15:1817-1832. 2001
  • Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors.  15:839-844. 2001
  • A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo.  14:2534-2546. 2000
  • Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.  14:2298-2313. 2000
  • Assembly of functionally active Drosophila origin recognition complex from recombinant proteins.  13:1289-1296. 1999
  • Erratum: Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaos at centromeric heterochromatin (Genes and Development (1998) 12 (782-796)).  12:1240. 1998
  • Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin.  12:782-796. 1998
  • The bZIP transcription factor LCR-F1 is essential for mesoderm formation in mouse development.  11:786-798. 1997
  • Association of an activator with an RNA polymerase II holoenzyme.  9. 1995
  • Association of an activator with an RNA polymerase II holoenzyme.  9:897-910. 1995
  • Differentiation-dependent up-regulation of the human papillomavirus E7 gene reactivates cellular DNA replication in suprabasal dlfferentiated keratinocytes.  9:2335-2349. 1995
  • Regulation of pyrBI operon expression in Escherichia coli by UTP-sensitive reiterative RNA synthesis during transcriptional initiation..  8:2904-2912. 1994
  • The v-abl tyrosine kinase negatively regulates NF-κB/Rel factors and blocks κ gene transcription in pre-B lymphocytes.  8:678-687. 1994
  • Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE..  7:1535-1548. 1993
  • Production of human papillomavirus and modulation of the infectious program in epithelial raft cultures.  6:1131-1142. 1992
  • The cloned RNA polymerase II transcription factor IID selects RNA polymerase III to transcribe the human U6 gene in vitro..  5:1477-1489. 1991
  • A novel enhancer in the immunoglobulin λ locus is duplicated and functionally independent of NFκB.  4:978-992. 1990
  • Human γ- To β-globin gene switching in transgenic mice.  4:380-389. 1990
  • Serum and v-src increase the level of a CCAAT-binding factor required for transcription from a retroviral long terminal repeat.  4:243-254. 1990
  • A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice..  3:314-323. 1989
  • Functional mapping of the human papillomavirus type 11 transcriptional enhancer and its interaction with the trans-acting E2 proteins..  2:54-67. 1988
  • International Standard Serial Number (issn)

  • 0890-9369
  • Electronic International Standard Serial Number (eissn)

  • 1549-5477