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Treatment-shortening effect of a novel regimen combining clofazimine and high-dose rifapentine in pathologically distinct mouse models of tuberculosis.
Activity of a long-acting injectable bedaquiline formulation in a paucibacillary mouse model of latent tuberculosis infection.
Pharmacokinetics of dapivirine transfer into blood plasma, breast milk, and cervicovaginal fluid of lactating women using the dapivirine vaginal ring.
A Protein Complex from Human Milk Enhances the Activity of Antibiotics and Drugs against Mycobacterium tuberculosis.
Amphotericin B induction with voriconazole consolidation as salvage therapy for FKS-associated echinocandin resistance in Candida glabrata septic arthritis and osteomyelitis.
Microbiological analysis from a phase 2 randomized study in adults evaluating single oral doses of gepotidacin in the treatment of uncomplicated urogenital gonorrhea caused by neisseria gonorrhoeae.
In vitro activities of the benzoquinolizine fluoroquinolone levonadifloxacin (WCK 771) and other antimicrobial agents against mycoplasmas and ureaplasmas in humans, including isolates with defined resistance mechanisms.
Impact of clofazimine dosing on treatment shortening of the first-line regimen in a mouse model of tuberculosis.
In vitro study of the susceptibility of clinical isolates of trichomonas vaginalis to metronidazole and secnidazole.
High prevalence of Pneumocystis jirovecii dihydropteroate synthase gene mutations in patients with a first episode of Pneumocystis pneumonia in Santiago, Chile, and clinical response to trimethoprim-sulfamethoxazole therapy.
In vitro activities of lefamulin and other antimicrobial agents against macrolide-susceptible and macrolide-resistant Mycoplasma pneumoniae from the United States, Europe, and China.
In vitro activities of gepotidacin (GSK2140944) and other antimicrobial agents against human mycoplasmas and ureaplasmas.
Susceptibility of Mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c.
In vitro activities of omadacycline (PTK 0796) and other antimicrobial agents against human mycoplasmas and ureaplasmas.
Emtricitabine-Triphosphate in dried blood spots as a marker of recent dosing.
8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosis.
In vitro exposure to PC-1005 and cervicovaginal lavage fluid from women vaginally administered PC-1005 inhibits HIV-1 and HSV-2 infection in human cervical mucosa.
Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic manner.
In Vitro antibacterial activity of AZD0914 against human mycoplasmas and ureaplasmas.
The mycobacterium tuberculosis outer membrane channel protein CpnT confers susceptibility to toxic molecules.
Analysis of Neisseria gonorrhoeae azithromycin susceptibility in the united states by the gonococcal isolate surveillance project, 2005 to 2013.
Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization.
Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge.
Microbicidal power of alpha radiation in sterilizing germinating Bacillus anthracis spores.
Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus.
Pharmacokinetic and safety analyses of tenofovir and tenofovir- emtricitabine vaginal tablets in pigtailed macaques.
Randomized, double-blind, multicenter safety and efficacy study of rifalazil compared with azithromycin for treatment of uncomplicated genital Chlamydia trachomatis infection in women.
Association of higher plasma vitamin d binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: Cause of a functional Vitamin D deficiency?.
Azithromycin to prevent bronchopulmonary dysplasia in Ureaplasma-infected preterm infants: Pharmacokinetics, safety, microbial response, and clinical outcomes with a 20-milligram-per-kilogram single intravenous dose.
Real-time treatment guidelines: Considerations during the Exserohilum rostratum outbreak in the United States.
Reduced vancomycin susceptibility in an in vitro catheter-related biofilm model correlates with poor therapeutic outcomes in experimental endocarditis due to methicillin-resistant staphylococcus aureus.
Copper-boosting compounds: A novel concept for antimycobacterial drug discovery.
Novel method to assess antiretroviral target trough concentrations using in vitro susceptibility data.
Use of xylitol to enhance the therapeutic efficacy of polymethylmethacrylate-based antibiotic therapy in treatment of chronic osteomyelitis.
Nevirapine exposure with WHO pediatric weight band dosing: Enhanced therapeutic concentrations predicted based on extensive international pharmacokinetic experience.
Safety and tolerability of voriconazole in patients with baseline renal insufficiency and candidemia.
Chromosomal mutations responsible for fluoroquinolone resistance in Ureaplasma species in the United States.
Oseltamivir inhibits H7 influenza virus replication in mice inoculated by the ocular route.
Identification of protein-protein interaction inhibitors targeting vaccinia virus processivity factor for development of antiviral agents.
A high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na +-driven flagellar motor and virulence gene expression in Vibrio cholerae.
Steady-state pharmacokinetics of tenofovir-based regimens in HIV-infected pediatric patients.
In Vitro echinocandin susceptibility of Aspergillus isolates from patients enrolled in the transplant-associated infection surveillance network.
A new small molecule specifically inhibits the cariogenic bacterium Streptococcus mutans in multispecies biofilms.
Decrease in penicillin susceptibility due to heat shock protein ClpL in Streptococcus pneumoniae.
Three residues in HIV-1 matrix contribute to protease inhibitor susceptibility and replication capacity.
Phase 2a study of the CCR5 monoclonal antibody PRO 140 administered intravenously to HIV-infected adults.
Azithromycin alters macrophage phenotype and pulmonary compartmentalization during lung infection with Pseudomonas.
Evaluation of vancomycin and daptomycin potency trends (MIC Creep) against methicillin-resistant Staphylococcus aureus isolates collected in nine U.S. Medical Centers from 2002 to 2006 (Antimicrobial Agents and Chemotherapy (2009) 53, 10, (4127-4132)).
Efficacy profiles of daptomycin for treatment of invasive and noninvasive pulmonary infections with Streptococcus pneumoniae.
Inhibition of herpesvirus replication by 5-substituted 4′- thiopyrimidine nucleosides.
Evaluation of vancomycin and daptomycin potency trends (MIC creep) against methicillin-resistant Staphylococcus aureus isolates collected in nine U.S. Medical Centers from 2002 to 2006.
Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101.
Activities of certain 5-substituted 4′-thiopyrimidine nucleosides against orthopoxvirus infections.
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
Comparative in vitro activities of the investigational fluoroquinolone DC-159a and other antimicrobial agents against human mycoplasmas and ureaplasmas.
Association of fluconazole pharmacodynamics with mortality in patients with candidemia.
Role of porins for uptake of antibiotics by Mycobacterium smegmatis.
Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis.
Dectin-1 Fc targeting of Aspergillus fumigatus beta-glucans augments innate defense against invasive pulmonary aspergillosis.
Pharmacokinetics of antiretroviral regimens containing tenofovir disoproxil fumarate and atazanavir-ritonavir in adolescents and young adults with human immunodeficiency virus infection.
Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.
Effect of concomitantly administered rifampin on the pharmacokinetics and safety of atazanavir administered twice daily.
Clinical response and tolerability to and safety of saquinavir with low-dose ritonavir in human immunodeficiency virus type 1-infected mothers and their infants.
Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.
EthA, a common activator of thiocarbamide-containing drugs acting on different mycobacterial targets.
Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.
Antimicrobial susceptibility among pathogens collected from hospitalized patients in the United States and in vitro activity of tigecycline, a new glycylcycline antimicrobial.
Enteroviral meningitis: Natural history and outcome of pleconaril therapy.
Novel conjugate of moxifloxacin and carboxymethylated glucan with enhanced activity against Mycobacterium tuberculosis.
New Mycobactenum avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors.
Analysis of human immunodeficiency virus type 1 reverse transcriptase subunit structure/function in the context of infectious virions and human target cells.
Lipophilic antifolate trimetrexate is a potent inhibitor of trypanosoma cruzi: Prospect for chemotherapy of chagas' disease.
Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas.
Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models.
Phase I evaluation of the safety and pharmacokinetics of murine-derived anticryptococcal antibody 18B7 in subjects with treated cryptococcal meningitis.
Multidrug resistance of a porin deletion mutant of Mycobacterium smegmatis.
Insufficient Evidence that Extended-Spectrum Cephalosporins Effectively Prevent Metastatic Infections Related to Klebsiella pneumoniae-Caused Liver Abscess.
SRI-286, a thiosemicarbazole, in combination with mefloquine and moxifloxacin for treatment of murine Mycobacterium avium complex disease.
Bis-Anthracycline Antibiotics Inhibit Human Immunodeficiency Virus Type 1 Transcription.
Orally active fusion inhibitor of respiratory syncytial virus..
Pharmacokinetics of Saquinavir plus Low-Dose Ritonavir in Human Immunodeficiency Virus-Infected Pregnant Women?.
Comparative In Vitro Susceptibilities and Bactericidal Activities of Investigational Fluoroquinolone ABT-492 and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas.
Genotypes of Pneumocystis jiroveci Isolates Obtained in Harare, Zimbabwe, and London, United Kingdom.
Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States.
Uptake of nitrobenzylthioinosine and purine β-L-nucleosides by intracellular Toxoplasma gondii.
Thiosemicarbazole (thiacetazone-like) compound with activity against Mycobacterium avium in mice.
Methodologies and cell lines used for antimicrobial susceptibility testing of Chlamydia spp..
Prevalence of plasmid-mediated quinolone resistance.
In vitro activities of ABT-773 and other antimicrobials against human mycoplasmas.
In vitro susceptibilities to and bactericidal activities of garenoxacin (BMS-284756) and other antimicrobial agents against human mycoplasmas and ureaplasmas.
Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.
Safety, tolerance, and pharmacokinetics of high-dose liposomal amphotericin B (AmBisome) in patients infected with Aspergillus species and other filamentous fungi: Maximum tolerated dose study.
Trends in antifungal drug susceptibility of Cryptococcus neoformans isolates in the United States: 1992 to 1994 and 1996 to 1998.
Acyclovir for treatment of postherpetic neuralgia: Efficacy and pharmacokinetics.
Antimicrobial activities of gatifloxacin against nosocomial isolates of Stenotrophomonas maltophilia measured by MIC and time-kill studies.
Pharmacological basis for concentration-controlled therapy with zidovudine, lamivudine, and indinavir.
Safety and pharmacokinetics of once-daily regimens of soft-gel capsule saquinavir plus minidose ritonavir in human immunodeficiency virus-negative adults.
Intracellular metabolism of β-L-2',3'-dideoxyadenosine: Relevance to its limited antiviral activity.
Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells.
Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase.
In vitro susceptibilities of Mycoplasma hominis to six fluoroquinolones as determined by E test.
Metabolism and selective toxicity of 6-nitrobenzylthioinosine in Toxoplasma gondii.
In vitro activities of several diaminomethylpyridopyrimidines against Mycobacterium avium complex.
Bactericidal activities of ceftizoxime and cefotaxime against Streptococcus pneumoniae  (multiple letters).
Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: Results from a randomized, controlled clinical trial.
Sorivudine versus acyclovir for treatment of dermatomal herpes zoster in human immunodeficiency virus-infected patients: results from a randomized, controlled clinical trial. Collaborative Antiviral Study Group/AIDS Clinical Trials Group, Herpes Zoster Study Group..
Comparison of single-dose oral grepafloxacin with cefixime for treatment of uncomplicated gonorrhea in men.
Comparative in vitro antimicrobial susceptibilities of nosocomial isolates of Acinetobacter baumannii and synergistic activities of nine antimicrobial combinations.
Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains.
Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS.
Structure-activity relationships of quinolone agents against Mycobacteria: Effect of structural modifications at the 8 position.
Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections.
Population pharmacokinetics of ganciclovir in newborns with congenital cytomegalovirus infections. NIAID Collaborative Antiviral Study Group..
Dose-ranging study of CP-99,219 (trovafloxacin) for treatment of uncomplicated gonorrhea.
Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitors.
Mutacin II, a bactericidal lantibiotic from Streptococcus mutans.
Trends in susceptibility of Neisseria gonorrhoeae to ceftriaxone from 1985 through 1991.
Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene.
Decreased susceptibility to penicillin G and tet M plasmids in genital and anorectal isolates of Neisseria meningitidis.
Comparison of ciprofloxacin and ceftriaxone as single-dose therapy for uncomplicated gonorrhea in women.
Cocaine hydrochloride and benzoylecgonine have no in vitro inhibitory effect against Neisseria gonorrhoeae.
In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391.
INVITRO SUSCEPTIBILITY OF MUTANS STREPTOCOCCI TO ANTIMICROBIAL SUBSTANCES AS DETERMINED BY A MEMBRANE TRANSFER ASSAY.
In vitro susceptibility of mutans streptococci to antimicrobial substances as determined by a membrane transfer assay..
Multicenter randomized study of single-dose ofloxacin versus amoxicillin-probenecid for treatment of uncomplicated gonococcal infection.
Prevention for tubercidin host toxicity by nitrobenzylthioinosine 5'-monophosphate for the treatment of schistosomiasis.
Azole antifungal agents: Emphasis on new triazoles.
In vitro susceptibilities of mycoplasmas and ureaplasmas to new macrolides and aryl-fluoroquinolones.
Treatment of uncomplicated gonorrhea with single-dose imipenem-cilastatin.
In vitro susceptibilities of suspected periodontopathic anaerobes as determined by membrane transfer assay.
Pharmacokinetics and tolerance of desciclovir, a prodrug of acyclovir, in healthy human volunteers.
Comparative study of cefoperazone and spectinomycin for treatment of uncomplicated gonorrhea in men.
Comparative trial of single-dose ciprofloxacin and ampicillin plus probenecid for treatment of gonococcal urethritis in men.
Dose ranging study of cefpimizole (U-63196E) for treatment of uncomplicated gonorrhea in men.
In vitro activity of piperacillin, ticarcillin, and mezlocillin alone and in combination with aminoglycosides against Pseudomonas aeruginosa.
Ribavirin small-particle aerosol treatment of infections caused by influenza virus strains A/Victoria/7/83 (H1N1) and B/Texas/1/84..
High-pressure liquid chromatographic methods for determining arabinosyladenine-5'-monophosphate, arabinosyladenine, and arabinosylhypoxanthine in plasma and urine.
Clinical evaluation of moxalactam.
Penetration of spectinomycin into cerebrospinal fluid during experimental meningitis.
Pharmacology, tolerance, and antiviral activity of vidarabine monophosphate in humans.
Characterization and extrachromosomal control of bacteriocin production in Staphylococcus aureus..
Mode of action of a Staphylococcus epidermidis bacteriocin..