Scientific Reports

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data.  9. 2019

A blood-based signature of cerebrospinal fluid Aβ 1–42 status.  9. 2019

A feasibility study for predicting optimal radiation therapy dose distributions of prostate cancer patients from patient anatomy using deep learning.  9. 2019

A gene expression network analysis of the pancreatic islets from lean and obese mice identifies complement 1q like-3 secreted protein as a regulator of β-cell function.  9. 2019

A simple genotyping method to detect small CRISPR-Cas9 induced indels by agarose gel electrophoresis.  9. 2019

Author Correction: The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas (Scientific Reports, (2019), 9, 1, (4299), 10.1038/s41598-019-40683-7).  9. 2019

CC chemokines are differentially expressed in Breast Cancer and are associated with disparity in overall survival.  9. 2019

Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity.  9. 2019

Deciphering Role of Wnt Signalling in Cardiac Mesoderm and Cardiomyocyte Differentiation from Human iPSCs: Four-dimensional control of Wnt pathway for hiPSC-CMs differentiation.  9. 2019

Depletion of dietary aryl hydrocarbon receptor ligands alters microbiota composition and function.  9. 2019

Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton.  9. 2019

Early Life Supraphysiological Levels of Oxygen Exposure Permanently Impairs Hippocampal Mitochondrial Function.  9. 2019

Erythropoietin (EPO) haplotype associated with all-cause mortality in a cohort of Italian patients with Type-2 Diabetes.  9. 2019

FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.  9. 2019

FGFR4 does not contribute to progression of chronic kidney disease.  9. 2019

Fabrication of dual-functional composite yarns with a nanofibrous envelope using high throughput AC needleless and collectorless electrospinning.  9. 2019

Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.  9. 2019

Higher CXCL16 exodomain is associated with aggressive ovarian cancer and promotes the disease by CXCR6 activation and MMP modulation.  9. 2019

Host–symbiont combinations dictate the photo-physiological response of reef-building corals to thermal stress.  9. 2019

Insights into the antigenic advancement of influenza A(H3N2) viruses, 2011–2018.  9. 2019

Lattice disorder effect on magnetic ordering of iron arsenides.  9. 2019

Methylmercury exposure, genetic variation in metabolic enzymes, and the risk of glioma.  9. 2019

Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification.  9. 2019

NeuroD2 controls inhibitory circuit formation in the molecular layer of the cerebellum.  9. 2019

O-GlcNAc stimulation: A new metabolic approach to treat septic shock.  9. 2019

Overall survival is improved when DCIS accompanies invasive breast cancer.  9. 2019

Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1 ^+/−/ODC transgenic mice.  9. 2019

Predicting Alzheimer’s disease progression using multi-modal deep learning approach.  9. 2019

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics.  9. 2019

Serum amino acid concentrations and clinical outcomes in smokers: SPIROMICS metabolomics study.  9. 2019

Signature profile of cyclooxygenase-independent F2 series prostaglandins in C. elegans and their role in sperm motility.  9. 2019

Telencephalon transcriptome analysis of chronically stressed adult zebrafish.  9. 2019

The browning and re-browning of lakes: Divergent lake-water organic carbon trends linked to acid deposition and climate change.  9. 2019

The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas.  9. 2019

The in vivo specificity of synaptic Gβ and Gγ subunits to the α2a adrenergic receptor at CNS synapses.  9. 2019

Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels.  9. 2019

Widespread diminishing anthropogenic effects on calcium in freshwaters.  9. 2019

A 2′FY-RNA Motif Defines an Aptamer for Ebolavirus Secreted Protein.  8. 2018

A highly potent and broadly neutralizing H1 influenza-specific human monoclonal antibody.  8. 2018

Age at first birth in women is genetically associated with increased risk of schizophrenia.  8. 2018

Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains.  8. 2018

Angiogenic and Osteogenic Synergy of Human Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells Cocultured on a Nanomatrix.  8. 2018

Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation during Pneumonia.  8. 2018

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states.  8. 2018

CCR5/CCL5 axis interaction promotes migratory and invasiveness of pancreatic cancer cells.  8. 2018

CD38 promotes pristane-induced chronic inflammation and increases susceptibility to experimental lupus by an apoptosis-driven and TRPM2-dependent mechanism.  8. 2018

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease.  8. 2018

Characterization of different bubble formulations for blood-brain barrier opening using a focused ultrasound system with acoustic feedback control.  8. 2018

Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteins.  8. 2018

Combinatorial drug testing in 3D microtumors derived from GBM patient-derived xenografts reveals cytotoxic synergy in pharmacokinomics-informed pathway interactions.  8. 2018

Cross-species transcriptional analysis reveals conserved and host-specific neoplastic processes in mammalian glioma.  8. 2018

Distinct systemic microbiome and microbial translocation are associated with plasma level of anti-CD4 autoantibody in HIV infection.  8. 2018

Effects of gadolinium on cardiac mechanosensitivity in whole isolated swine hearts.  8. 2018

Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression.  8. 2018

Erratum to: An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications (Scientific Reports, (2015), 5, 1, (17105), 10.1038/srep17105).  8. 2018

FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived Xenografts.  8. 2018

Gemcitabine treatment promotes immunosuppressive microenvironment in pancreatic tumors by supporting the infiltration, growth, and polarization of macrophages.  8. 2018

Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells.  8. 2018

Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates /631/326/596 /692/699/255/1901 /82/58 /38/91 /82/80 article.  8. 2018

In vivo optic nerve head mechanical response to intraocular and cerebrospinal fluid pressure: imaging protocol and quantification method.  8. 2018

Investigation of 20S-hydroxyVitamin D3 analogs and their 1α-OH derivatives as potent Vitamin D receptor agonists with anti-inflammatory activities.  8. 2018

Monitoring the past and choosing the future: The prefrontal cortical influences on voluntary action.  8. 2018

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images.  8. 2018

New Spirometry Indices for Detecting Mild Airflow Obstruction.  8. 2018

Open-Label Placebo Treatment for Cancer-Related Fatigue: A Randomized-Controlled Clinical Trial.  8. 2018

PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells.  8. 2018

Performance of Deep Learning Architectures and Transfer Learning for Detecting Glaucomatous Optic Neuropathy in Fundus Photographs.  8. 2018

RHYTHM: An Open Source Imaging Toolkit for Cardiac Panoramic Optical Mapping.  8. 2018

Rapid Growth of Nanocrystalline Diamond on Single Crystal Diamond for Studies on Materials under Extreme Conditions.  8. 2018

Socioeconomic Status and Race are both Independently associated with Increased Hospitalization Rate among Crohn's Disease Patients.  8. 2018

Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory.  8. 2018

The phosphatase PPM1A controls monocyte-to-macrophage differentiation.  8. 2018

Transitions from Ideal to Intermediate Cholesterol Levels may vary by Cholesterol Metric.  8. 2018

Unique Lipid Signatures of Extracellular Vesicles from the Airways of Asthmatics.  8. 2018

Erratum: Author Correction: Transitions from Ideal to Intermediate Cholesterol Levels may vary by Cholesterol Metric (Scientific reports (2018) 8 1 (2782)).  8:6238. 2018

1α,20S-Dihydroxyvitamin D Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis.  7. 2017

Altered miRNA expression network in locus coeruleus of depressed suicide subjects.  7. 2017

Cancer-associated fibroblasts support vascular growth through mechanical force.  7. 2017

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features.  7. 2017

Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols.  7. 2017

Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression.  7. 2017

Electrophysiological Properties and Viability of Neonatal Rat Ventricular Myocyte Cultures with Inducible ChR2 Expression.  7. 2017

Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis.  7. 2017

FGF23/FGFR4-mediated left ventricular hypertrophy is reversible.  7. 2017

Global temporal dynamic landscape of pathogen-mediated subversion of Arabidopsis innate immunity.  7. 2017

Kinetic and Structural Characterization of the Effects of Membrane on the Complex of Cytochrome b 5 and Cytochrome c.  7. 2017

Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia.  7. 2017

Knockout of the ATPase inhibitory factor 1 protects the heart from pressure overload-induced cardiac hypertrophy.  7. 2017

Knowledge-Transfer learning for prediction of matrix metalloprotease substrate-cleavage sites.  7. 2017

Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways.  7. 2017

Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model.  7. 2017

NADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4.  7. 2017

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty.  7. 2017

PhosphoPredict: A bioinformatics tool for prediction of human kinase-specific phosphorylation substrates and sites by integrating heterogeneous feature selection.  7. 2017

Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model.  7. 2017

Resolution Agonist 15-epi-Lipoxin A4 Programs Early Activation of Resolving Phase in Post-Myocardial Infarction Healing.  7. 2017

Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells.  7. 2017

Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment.  7. 2017

Structure-Based Discovery of Small Molecule Inhibitors of Cariogenic Virulence.  7. 2017

The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology.  7. 2017

The Human Blood-Nerve Barrier Transcriptome.  7. 2017

The Matrikine Acetylated Proline-Glycine-Proline Couples Vascular Inflammation and Acute Cardiac Rejection.  7. 2017

The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.  7. 2017

Transcriptomic Biomarkers to Discriminate Bacterial from Nonbacterial Infection in Adults Hospitalized with Respiratory Illness.  7. 2017

Transcriptomics reveals multiple resistance mechanisms against cotton leaf curl disease in a naturally immune cotton species, Gossypium arboreum.  7. 2017

Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors.  7. 2017

Erratum: Molecular analysis of the factorless internal ribosome entry site in Cricket Paralysis virus infection.  7:39439. 2017

The development of novel LTA4 H modulators to selectively target LTB4 generation.  7. 2017

Amplified centrosomes and mitotic index display poor concordance between patient tumors and cultured cancer cells.  7. 2017

Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia.  7. 2017

Endothelin receptor-specific control of endoplasmic reticulum stress and apoptosis in the kidney.  7. 2017

Extracellular Superoxide Dismutase Expression in Papillary Thyroid Cancer Mesenchymal Stem/Stromal Cells Modulates Cancer Cell Growth and Migration.  7. 2017

GARP2 accelerates retinal degeneration in rod cGMP-gated cation channel β-subunit knockout mice.  7. 2017

Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis.  7. 2017

An Assessment of the Contrast Sensitivity in Patients with Ametropic and Anisometropic Amblyopia in Achieving the Corrected Visual Acuity of 1.0.  7. 2017

Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling.  7. 2017

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease.  7. 2017

Echo-planar J-resolved spectroscopic imaging using dual read-outs: implementation and quantitation of human brain metabolites.  7:1-11. 2017

Prior-knowledge fitting of accelerated five-dimensional echo planar J-resolved spectroscopic imaging: effect of nonlinear reconstruction on quantitation.  7:1-12. 2017

Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples.  6. 2016

From Function to Phenotype: Impaired DNA Binding and Clustering Correlates with Clinical Severity in Males with Missense Mutations in MECP2.  6. 2016

TGF-β regulates phosphorylation and stabilization of Sox9 protein in chondrocytes through p38 and Smad dependent mechanisms.  6. 2016

Regulation of α2B-Adrenergic Receptor Cell Surface Transport by GGA1 and GGA2.  6. 2016

Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary Fibrosis.  6. 2016

Molecular analysis of the factorless internal ribosome entry site in Cricket Paralysis virus infection.  6. 2016

MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes.  6. 2016

Defining cutaneous molecular pathobiology of arsenicals using phenylarsine oxide as a prototype.  6. 2016

ALB3 Insertase Mediates Cytochrome b 6 Co-translational Import into the Thylakoid Membrane.  6. 2016

High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1.  6. 2016

Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling.  6. 2016

Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization.  6. 2016

A distinct sortase SrtB anchors and processes a streptococcal adhesin AbpA with a novel structural property.  6. 2016

The Airway Microbiome at Birth.  6. 2016

Mitofusin-2 is required for mouse oocyte meiotic maturation.  6. 2016

Novel HDAd/EBV Reprogramming Vector and Highly Efficient Ad/CRISPR-Cas Sickle Cell Disease Gene Correction.  6. 2016

Cdk5 Modulates Long-Term Synaptic Plasticity and Motor Learning in Dorsolateral Striatum.  6. 2016

Efficacy of Statin Therapy in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis.  6. 2016

A microscopic landscape of the invasive breast cancer genome.  6. 2016

In vivo organ specific drug delivery with implantable peristaltic pumps.  6. 2016

Deregulated hedgehog pathway signaling is inhibited by the smoothened antagonist LDE225 (Sonidegib) in chronic phase chronic myeloid leukaemia.  6. 2016

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy.  6. 2016

Cortical thickness in human V1 associated with central vision loss.  6. 2016

MiR-429 regulates the transition between Hypoxia-Inducible Factor (HIF)1A and HIF3A expression in human endothelial cells.  6. 2016

Integrative topological analysis of mass spectrometry data reveals molecular features with clinical relevance in esophageal squamous cell carcinoma.  6. 2016

Impact of L-carnitine on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials.  6. 2016

Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins.  6. 2016

An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications.  5. 2015

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis.  5. 2015

Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.  5. 2015

Hybrid electrodes by in-situ integration of graphene and carbon-nanotubes in polypyrrole for supercapacitors.  5. 2015

QIAD assay for quantitating a compounds efficacy in elimination of toxic Aβ oligomers.  5. 2015

N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells.  5. 2015

In Vivo Fluorescence Immunohistochemistry: Localization of Fluorescently Labeled Cetuximab in Squamous Cell Carcinomas.  5. 2015

Ghrelin agonist does not foster insulin resistance but improves cognition in an Alzheimer's disease mouse model.  5. 2015

Shot-noise Limited Faraday Rotation Spectroscopy for Detection of Nitric Oxide Isotopes in Breath, Urine, and Blood.  5. 2015

A Dual-Reporter System for Real-Time Monitoring and High-throughput CRISPR/Cas9 Library Screening of the Hepatitis C Virus.  5. 2015

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.  5. 2015

Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics.  5. 2015

Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production.  5. 2015

Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension.  5. 2015

Polarization selective phase-change nanomodulator.  4. 2014

Feasibility of isotope harvesting at a projectile fragmentation facility: ⁶⁷Cu.  4. 2014

Fully automated high-throughput chromatin immunoprecipitation for ChIP-seq: Identifying ChIP-quality p300 monoclonal antibodies.  4. 2014

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.  4. 2014

Formation mechanism of chalcogenide nanocrystals confined inside genetically engineered virus-like particles.  4. 2014

In vivo optical coherence tomography of light-driven melanosome translocation in retinal pigment epithelium.  3. 2013