Journal of Pharmacology and Experimental Therapeutics

Acetate, a short-chain fatty acid, acutely lowers heart rate and cardiac contractility along with blood pressure.  377:39-50. 2021

Functional interaction of endothelin receptors in mediating natriuresis evoked by G protein–Coupled estrogen receptor 1.  376:98-105. 2021

Correction to: Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson’s disease(J Pharmacol Exp Ther. (2013) 345: 1 (125-38) DOI: 10.1124/jpet.112.201558).  369:66. 2019

Diisopropylfluorophosphate Impairs the Transport of Membrane-Bound Organelles in Rat Cortical Axons..  356:645-655. 2016

Combined endothelin a blockade and chlorthalidone treatment in a rat model of metabolic syndrome.  351:467-473. 2014

Therapeutic targeting of Src kinase in myofibroblast differentiation and pulmonary fibrosis.  351:87-95. 2014

Effect of isoflurane on myocardial energetic and oxidative stress in cardiac muscle from Zucker diabetic fatty rat.  349:21-28. 2014

Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.  345:125-138. 2013

Correction to "The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys" (J Pharmacol Exp Ther (2011) 336, (682-692)).  342:596. 2012

Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-hexylpyridylporphyrin, MnTnHex-2-PyP: Rodent models of ischemic stroke and subarachnoid hemorrhage.  338:906-916. 2011

Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease.  338:263-270. 2011

Behavioral and cellular modulation of L-DOPA-induced dyskinesia by β-adrenoceptor blockade in the 6-hydroxydopamine-lesioned rat.  337:755-765. 2011

The mitochondria-targeted antioxidant mitoquinone protects against cold storage injury of renal tubular cells and rat kidneys.  336:682-692. 2011

The prototypical ranitidine analog JWS-USC-75-IX improves information processing and cognitive function in animal models.  336:751-766. 2011

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.  334:430-438. 2010

Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats.  335:124-132. 2010

Silibinin attenuates amyloid β25-35 peptide-induced memory impairments: Implication of inducible nitric-oxide synthase and tumor necrosis factor-α in mice.  331:319-326. 2009

Rats self-administer intravenous nicotine delivered in a novel smoking-relevant procedure: Effects of dopamine antagonists.  330:633-640. 2009

Identification of human CYP2C8 as a retinoid-related orphan nuclear receptor target gene.  329:192-201. 2009

Increased oxidant activity mediates vascular dysfunction in vibration injury.  328:223-230. 2009

Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.  322:678-685. 2007

A comparison between ranolazine and CVT-4325, a novel inhibitor of fatty acid oxidation, on cardiac metabolism and left ventricular function in rat isolated perfused heart during ischemia and reperfusion.  321:213-220. 2007

Chronic activation of peroxisome proliferator-activated receptor-α with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure.  321:165-171. 2007

Insulin replacement restores the behavioral effects of quinpirole and raclopride in streptozotocin-treated rats.  320:1216-1223. 2007

Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta.  315:1058-1064. 2005

Transforming growth factor-β-dependent growth inhibition in primary vascular smooth muscle cells is p38-dependent.  315:1005-1012. 2005

P2X receptor-stimulated calcium responses in preglomerular vascular smooth muscle cells involves 20-hydroxyeicosatetraenoic acid.  311:1211-1217. 2004

Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1.  310:469-476. 2004

The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes.  310:52-58. 2004

Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque.  309:127-136. 2004

Roles of Catalase and Hydrogen Peroxide in Green Tea Polyphenol-Induced Chemopreventive Effects.  308:317-323. 2004

Nucleotide-induced restoration of conjunctival chloride and fluid secretion in adenovirus type 5-infected pigmented rabbit eyes.  305:1206-1211. 2003

Phosphorylation of 4′-thio-β-D-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase.  304:1314-1322. 2003

Differential effects of haloperidol and clozapine on [³H]cAMP binding, protein kinase A (PKA) activity, and mRNA and protein expression of selective regulatory and catalytic subunit isoforms of PKA in rat brain.  301:197-209. 2002

Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.  300:324-329. 2002

Modifications in the phosphoinositide signaling pathway by adrenal glucocorticoids in rat brain: Focus on phosphoinositide-specific phospholipase C and inositol 1,4,5-trisphosphate.  295:244-254. 2000

A mibefradil metabolite is a potent intracellular blocker of L-type Ca²⁺ currents in pancreatic β-cells.  292:939-943. 2000

Adrenal glucocorticoids modulate [³H]cyclic AMP binding to protein kinase A (PKA), cyclic AMP-dependent PKA activity, and protein levels of selective regulatory and catalytic subunit isoforms of PKA in rat brain.  294:103-116. 2000

Effects of treatment with haloperidol, chlorpromazine, and clozapine on protein kinase C (PKC) and phosphoinositide-specific phospholipase C (PI-PLC) activity and on mRNA and protein expression of PKC and PLC isozymes in rat brain.  291:688-704. 1999

Acute regulation of norepinephrine transport: I. Protein kinase C- linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells.  287:733-743. 1998

Efficiency of plasmid delivery and expression after lipid-mediated gene transfer to human cells in vitro.  279:1462-1469. 1996

Use of nitric oxide-nucleophile adducts as biological sources of nitric oxide: Effects on airway smooth muscle.  278:1269-1275. 1996

Inhibition of N-methyl-D-aspartate glutamate receptor subunit expression by antisense oligonucleotides reveals their role in striatal motor regulation.  276:342-352. 1996

Alkylglycosides enhance systemic absorption of insulin applied topically to the rat eye.  271:1274-1280. 1994

Patterns of messenger RNA expression for adrenergic receptor subtypes in the rat kidney.  268:1605-1611. 1994

Angiotensin II receptor blockade improves renal function in rats with reduced renal mass.  267:657-663. 1993

Inhibition of brain protein kinase C subtypes by lead..  264:757-761. 1993

Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits.  269:867-880. 1993

Effect of the ANF analog A68828 in cisplatin-induced acute renal failure.  257:1179-1183. 1991

Beneficial effect of the atrial natriuretic factor analog A68828 in postischemic acute renal failure.  255:1166-1169. 1990

Colonic absorption of insulin: An in vitro and in vivo evaluation.  248:567-572. 1989

Effects of phenothiazines on the Na⁺-H⁺ exchanger of the brush-border membrane from the proximal small intestine of the rabbit.  245:823-828. 1988

Thromboxane synthesis and actions in isolated adrenergic nerve (pheochromocytoma-12) cells.  247:43-46. 1988

Role of vasopressin in the cardiovascular effects of LY171555, a selective dopamine D2 receptor agonist: Studies in conscious Brattleboro and Long-Evans rats.  242:143-151. 1987

Inhibition of brush-border membrane Na⁺-H⁺ exchanger by loperamide.  243:150-154. 1987

Inhibition of human placental Na⁺-H⁺ exchanger by cimetidine.  239:192-197. 1986

Mechanism of the depressor action of LY171555, a selective dopamine D2 receptor agonist, in the anesthetized rat.  239:426-432. 1986

Effects of the diethylamino analog of ethmozin (ethacizin) upon sympathetic and parasympathetic efferent activity to the canine heart.  236:75-79. 1986

Mechanism of the pressor action of LY171555, a specific dopamine D2 receptor agonist, in the conscious rat.  236:735-742. 1986

Increased renal tubular sodium pump and Na⁺,K⁺-adenosine triphosphatase in streptozotocin-diabetic rats.  229:664-670. 1984

Indirect stimulatory action of the calcium channel blocker AQA-39.  230:336-340. 1984

Mechanism of the depressor effect of bromocriptine in the spontaneously hypertensive rat.  228:370-375. 1984

The direct negative chronotropic action of prazosin on the canine sinus node.  221:801-805. 1982

Effects of adenosine on mechanical performance and electrical activity in the canine heart.  216:254-260. 1981

Selective effects of clonidine on the canine sinus node.  214:223-228. 1980

Termination of 'ventricular' arrhythmias from digoxin by selective production of complete atrioventricular block with physostigmine in the dog.  211:561-570. 1979

Properties of a pure metabolically active glomerular preparation from rat kidneys. I. Isolation.  187:332-341. 1973

Effects of ethacrynic acid on oxidative metabolism in isolated glomeruli..  187:352-364. 1973

Properties of a pure metabolically active glomerular preparation from rat kidneys. II. Metabolism..  187:342-351. 1973

Comparatve dependence on adrenergic neural tone by automaticity in the sinus node and in the atrioventricular junction.  187:269-279. 1973

Pharmacologic production of atrioventricular block with and without initial bundle branch block..  179:338-346. 1971