Circulation Research

Activation of Autophagic Flux Blunts Cardiac Ischemia/Reperfusion Injury. 2021

Cardiac Energy Metabolism in Heart Failure.  1487-1513. 2021

Chronobiological influence over cardiovascular function the good, the bad, and the ugly.  258-279. 2020

In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid.  207-224. 2020

Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.  125:957-968. 2019

Response by Pfeffer et al to Letter Regarding Article, "heart Failure with Preserved Ejection Fraction in Perspective".  125:E26. 2019

Heart Failure with Preserved Ejection Fraction in Perspective.  124:1598-1617. 2019

Treatment of Resistant and Refractory Hypertension.  124:1061-1070. 2019

Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure.  124:161-169. 2019

Lower blood pressure thresholds raise the bar in pregnancy.  125:195-197. 2019

Nuclear focal adhesion kinase controls vascular smooth muscle cell proliferation and neointimal hyperplasia through GATA4-mediated cyclin D1 transcription.  125:152-166. 2019

Lack of Remuscularization Following Transplantation of Human Embryonic Stem Cell-Derived Cardiovascular Progenitor Cells in Infarcted Nonhuman Primates.  122:958-969. 2018

E2F1 suppresses oxidative metabolism and endothelial differentiation of bone marrow progenitor cells.  122:701-711. 2018

CCND2 Overexpression Enhances the Regenerative Potency of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Remuscularization of Injured Ventricle.  122:88-96. 2018

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.  122:58-73. 2018

Can we engineer a human cardiac patch for therapy?.  123:244-265. 2018

Effective metabolic approaches for the energy starved failing heart: Bioenergetic resiliency via redundancy or something else?.  123:329-331. 2018

Global overview of the transnational alliance for regenerative therapies in cardiovascular syndromes (TACTICS) Recommendations: A comprehensive series of challenges and priorities of cardiovascular regenerative medicine.  122:199-201. 2018

Intra-cardiac release of extracellular vesicles shapes inflammation following myocardial infarction short communication.  123:100-106. 2018

Multifunctional role of chymase in acute and chronic tissue injury and remodeling.  122:319-336. 2018

Relationship between the efficacy of cardiac cell therapy and the inhibition of differentiation of human iPSC-Derived nonmyocyte cardiac cells into Myofibroblast-like cells.  123:1313-1325. 2018

Sprinting toward the optimal blood pressure target for hypertensive patients.  123:531-534. 2018

Transplanted mesenchymal stem cells reduce autophagic flux in infarcted hearts via the exosomal transfer of miR-125b.  123:564-578. 2018

PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy.  121:1370-1378. 2017

Meeting Report for the 2017 National Institutes of Health National Heart, Lung, and Blood Institute Progenitor Cell Biology Consortium: Cardiovascular Bioengineering Workshop and Symposium.  120:1709-1712. 2017

Immunomodulation is the key to cardiac repair.  120:1530-1532. 2017

Myocardial Tissue Engineering with Cells Derived from Human-Induced Pluripotent Stem Cells and a Native-Like, High-Resolution, 3-Dimensionally Printed Scaffold.  120:1318-1325. 2017

Elevating CXCR7 Improves Angiogenic Function of EPCs via Akt/GSK-3β/Fyn-Mediated Nrf2 Activation in Diabetic Limb Ischemia.  120:e7-e23. 2017

Reprogrammed Human Endothelial Cells: A Novel Cell Source for Regenerative Vascular Medicine..  120:756-758. 2017

From Microscale Devices to 3D Printing: Advances in Fabrication of 3D Cardiovascular Tissues.  120:150-165. 2017

A special report on the NHLBI initiative to study cellular and molecular mechanisms of arterial stiffness and its association with hypertension.  121:1216-1218. 2017

Lactate promotes synthetic phenotype in vascular smooth muscle cells.  121:1251-1262. 2017

Crossing into the Next Frontier of Cardiac Extracellular Matrix Research.  119:1040-1045. 2016

Meeting Report for NIH 2016 Progenitor Cell Biology Consortium Cardiovascular Tissue Engineering 2016.  119:981-983. 2016

Response by Zhou et al to Letter Regarding Article, Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy.  119:e29-e30. 2016

The biological basis for cardiac repair after myocardial infarction.  119:91-112. 2016

Assessing Cardiac Metabolism.  118:1659-1701. 2016

Loss of adult cardiac myocyte GSK-3 leads to mitotic catastrophe resulting in fatal dilated cardiomyopathy.  118:1208-1222. 2016

Long-Term Outcome of Administration of c-kit^POS Cardiac Progenitor Cells after Acute Myocardial Infarction: Transplanted Cells Do not Become Cardiomyocytes, but Structural and Functional Improvement and Proliferation of Endogenous Cells Persist for at Least One Year.  118:1091-1105. 2016

A large-scale investigation of hypoxia-preconditioned allogeneic mesenchymal stem cells for myocardial repair in nonhuman primates: Paracrine activity without remuscularization.  118:970-983. 2016

CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels..  118:230-240. 2016

Enhanced Reprogramming of Human Fibroblasts into Cardiomyocytes Using Minimal Transcription Factors.  119:A35-A35. 2016

The Nervous Heart: Role of Sympathetic Reinnervation in Cardiac Regeneration..  117:980-981. 2015

Abstract 221: Chronic Alterations of the Tissue Dendritic Cell and Macrophage Network Underlies the Th1 Response in the Failing Heart.  111:A221. 2015

Abstract 90: The Spleen Is an Essential Regulator of Systemic Neovascularization In Vivo.  111:A90. 2015

Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.  117:437-449. 2015

Bach1 represses Wnt/β-catenin signaling and angiogenesis.  117:364-375. 2015

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction.  117:52-64. 2015

New Approaches in the Treatment of Hypertension.  116:1074-1095. 2015

The GSK-3 family as therapeutic target for myocardial diseases.  116:138-149. 2015

Abstract 60: The Role of Mononuclear Phagocytes in Pressure Overload Heart Failure.  115:A60. 2014

PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.  115:504-517. 2014

OxLDL Triggers Retrograde Translocation of Arginase2 in Aortic Endothelial Cells via ROCK and Mitochondrial Processing Peptidase.  115:450-459. 2014

Sorafenib cardiotoxicity increases mortality after myocardial infarction.  114:1700-1712. 2014

Activation of AKT by O-linked N-Acetylglucosamine induces vascular calcification in diabetes mellitus.  114:1094-1102. 2014

It takes two to tango: Monocyte and macrophage duality in the infarcted heart.  114:1558-1560. 2014

Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure critical importance of the cardiosplenic axis.  114:266-282. 2014

Patching the heart: Cardiac repair from within and outside.  113:922-932. 2013

Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype.  111:1176-1189. 2012

Metabolic remodeling in the hypertrophic heart: Fuel for thought.  111:666-668. 2012

Smooth muscle cell-specific runx2 deficiency inhibits vascular calcification.  111:543-552. 2012

Bioenergetic and functional consequences of cellular therapy: Activation of endogenous Cardiovascular progenitor cells.  111:455-468. 2012

Enhanced angiogenic and cardiomyocyte differentiation capacity of epigenetically reprogrammed mouse and human endothelial progenitor cells augments their efficacy for ischemic myocardial repair.  111:180-190. 2012

Orai1 determines calcium selectivity of an endogenous trpc heterotetramer channel.  110:1435-1444. 2012

Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders.  110:915-921. 2012

Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles.  110:727-738. 2012

Response to the letter by Edwards et al.  110. 2012

Animal models of heart failure a scientific statement from the American Heart Association.  111:131-150. 2012

Hydrogen sulfide as endothelium-derived hyperpolarizing factor sulfhydrates potassium channels.  109:1259-1268. 2011

Interleukin-10 deficiency impairs bone marrow-derived endothelial progenitor cell survival and function in ischemic myocardium.  109:1280-1289. 2011

PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.  109:783-793. 2011

Translational success stories: Angiotensin receptor 1 antagonists in heart failure.  109:437-452. 2011

Lack of primary cilia primes shear-induced endothelial-to-mesenchymal transition.  108:1093-1101. 2011

ATP production rate via creatine kinase or ATP synthase in Vivo: A novel superfast magnetization saturation transfer method.  108:653-663. 2011

Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart.  108:437-445. 2011

Genetic variation in NCAM1 contributes to left ventricular wall thickness in hypertensive families.  108:279-283. 2011

Late-breaking basic science abstracts from the American Heart Association's Scientific Sessions 2010.  107. 2010

PGC-1 coactivators in cardiac development and disease.  107:825-838. 2010

Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.  107:242-251. 2010

Preferential oxidation of triacylglyceride-derived fatty acids in heart is augmented by the nuclear receptor PPARα.  107:233-241. 2010

Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.  107:117-125. 2010

Glycogen synthase kinase-3β regulates post-myocardial infarction remodeling and stress-induced cardiomyocyte proliferation in vivo.  106:1635-1645. 2010

Peroxisome proliferator-activated receptor δ is an essential transcriptional regulator for mitochondrial protection and biogenesis in adult heart.  106:911-919. 2010

Career moves: Induced pluripotent cells from human aortic smooth muscle cells can efficiently redifferentiate into parental phenotype.  106:7-9. 2010

Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury.  105:965-972. 2009

Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.  105:897-905. 2009

Direct Relationship Between Protein O-GlcNAcylation and the Cardiomyocyte Circadian Clock.  105:E50-E50. 2009

Increased Cardiomyocyte 0-linked-beta-N-acetylglucosamine (0-GlcNAc) Levels Induced by Glucose Deprivation Mediated by Decreased 0-GlcNAcase Expression and Reduced Hexosamine Biosynthesis Flux.  105:E34-E35. 2009

O-linked-beta-N-acetylglucosamine (O-GlcNAc) Mediated Ischemic Cardioprotection Associated with Increased O-GlcNAcylation of Cytoskeletal Z-Line Proteins.  105:E13-E13. 2009

Inducible Expression of Active Protein Phosphatase-1 Inhibitor-1 Enhances Basal Cardiac Function and Protects Against Ischemia/Reperfusion Injury.  104:1012-1020. 2009

IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR.  104. 2009

Unique hexosaminidase reduces metabolic survival signal and sensitizes cardiac myocytes to hypoxia/reoxygenation injury.  104:41-49. 2009

Cell-free embryonic stem cell extract-mediated derivation of multipotent stem cells from NIH3T3 fibroblasts for functional and anatomical ischemic tissue repair.  102. 2008

Endothelial arginase II: A novel target for the treatment of atherosclerosis.  102:923-932. 2008

Interleukin-1β causes acute lung injury via αvβ5 and αvβ6 integrin-dependent mechanisms.  102:804-812. 2008

Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4.  102:966-974. 2008

Atrial natriuretic peptide inhibits transforming growth factor β-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblasts.  102:185-192. 2008

Role of mitochondrial dysfunction in insulin resistance.  102:401-414. 2008

Heme-Egr-1: New partners in atherosclerotic progression?.  102:6-8. 2008

Inducible NO synthase-dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction.  101:692-702. 2007

Myocardial Smad4 is essential for cardiogenesis in mouse embryos.  101:277-285. 2007

Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis.  100:1703-1711. 2007

Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration.  100:654-661. 2007

Myocyte nitroso-redox imbalance in sepsis: NO simple answer.  100:1-4. 2007

The role of O-GlcNAcylation in aging-related loss of estrogenic vasoprotection.  99:1282-1282. 2006

APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt pathway via the phosphoinositol phosphatase SHIP2.  99:829-836. 2006

Free radicals, mitochondria, and oxidized lipids: The emerging role in signal transduction in vascular cells.  99:924-932. 2006

Oxidized low-density lipoprotein-dependent endothelial arginase II activation contributes to impaired nitric oxide signaling.  99:951-960. 2006

Cardiomyocyte-specific deletion of the coxsackievirus and adenovirus receptor results in hyperplasia of the embryonic left ventricle and abnormalities of sinuatrial valves.  98:923-930. 2006

Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function.  98:1098-1105. 2006

Coupled and uncoupled NOS: Separate but equal? Uncoupled NOS in endothelial cells is a critical pathway for intracellular signaling.  98:717-719. 2006

Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity.  98:119-124. 2006

Activation of the endothelial store-operated ISOC Ca ²⁺ channel requires interaction of protein 4.1 with TRPC4.  97:1164-1172. 2005

An apolipoprotein A-I mimetic works best in the presence of apolipoprotein A-I.  97:1085-1086. 2005

Oral small peptides render HDL antiinflammatory in mice and monkeys and reduce atherosclerosis in ApoE null mice.  97:524-532. 2005

Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide.  97:236-243. 2005

Glucosamine-induced cardioprotection mediated by the hexosamine biosynthesis pathway and increased levels of O-linked N-acetylglucosamine on nucleocytoplasmic proteins.  97:E28-E28. 2005

Essential role of a Ca²⁺-selective, store-operated current (ISOC) in endothelial cell permeability determinants of the vascular leak site.  96:856-863. 2005

Low-voltage-activated (T-type) calcium channels control proliferation of human pulmonary artery myocytes.  96:864-872. 2005

Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat.  96:277-279. 2005

Cytokine-induced modulation of cardiac function.  95:1140-1153. 2004

Apurinic/apyrmidinic endonuclease 1 regulates endothelial NO production and vascular tone.  95:902-910. 2004

Antiinflammatory properties of HDL.  95:764-772. 2004

Effects of electrical shocks on Cai²⁺ and V m in myocyte cultures.  94:1589-1597. 2004

Nitric oxide protects against pathological ventricular remodeling: Reconsideration of the role of NO in the failing heart.  94:1155-1157. 2004

Upregulation of Alveolar Epithelial Active Na⁺ Transport Is Dependent on β2-Adrenergic Receptor Signaling.  94:1091-1100. 2004

Genome-Wide Scan Identifies Novel QTLs for Cholesterol and LDL Levels in F2[Dahl RxS] Intercross Rats.  94:446-452. 2004

Nonlinear Changes of Transmembrane Potential, during Electrical Shocks: Role of Membrane Electroporation.  94:208-214. 2004

How do red blood cells dilate blood vessels?--Reply..  95. 2004

CaV3.1 (α1G) T-type Ca²⁺ channels mediate vaso-occlusion of sickled erythrocytes in lung microcirculation.  93:346-353. 2003

Nitric oxide regulation of myocardial contractility and calcium cycling: Independent impact of neuronal and endothelial nitric oxide synthases.  92:1322-1329. 2003

Gene therapy with inducible nitric oxide synthase protects against myocardial infarction via a cyclooxygenase-2-dependent mechanism.  92:741-748. 2003

Sustained reentry in the left ventricle of fibrillating pig hearts.  92:539-545. 2003

Vectorial sodium transport across the mammalian alveolar epithelium: It occurs but through which cells?.  92:348-349. 2003

Regional differences in ventricular fibrillation in the open-chest porcine left ventricle.  91:733-740. 2002

Effects of S-nitrosation and cross-linking of hemoglobin on hypoxic pulmonary vasoconstriction in isolated rat lungs.  91:626-632. 2002

Gene dosage-dependent effects of cardiac-specific overexpression of the A3 adenosine receptor.  91:165-172. 2002

Optical mapping of arrhythmias induced by strong electrical shocks in myocyte cultures.  90:664-670. 2002

Recent fibrillation studies: Attempts to wrest order from disorder.  89:1089-1091. 2001

Nitric oxide synthase (NOS2) mutation in Dahl/Rapp rats decreases enzyme stability.  89:317-322. 2001

Autonomous and growth factor - Induced hypertrophy in cultured neonatal mouse cardiac myocytes: Comparison with rat.  87:781-788. 2000

Nonlinear changes of transmembrane potential during defibrillation shocks: Role of Ca²⁺ current.  87:453-459. 2000

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells.  86:960-966. 2000

Fibrillating myocardium: Rabbit warren or beehive?.  86:369-370. 2000

Identification of cis elements in the cardiac troponin T gene conferring specific expression in cardiac muscle of transgenic mice..  86:478-484. 2000

The angiotensin II-dependent association of Jak2 and c-Src requires the N-terminus of Jak2 and the SH2 domain of c-Src.  84:1332-1338. 1999

Chemiluminescent detection of oxidants in vascular tissue: Lucigenin but not coelenterazine enhances superoxide formation.  84:1203-1211. 1999

Incidence, evolution, and spatial distribution of functional reentry during ventricular fibrillation in pigs.  84:945-954. 1999

ATP-sensitive K⁺ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise.  82:346-359. 1998

Activation of cardiac tissue by extracellular electrical shocks: Formation of 'secondary sources' at intercellular clefts in monolayers of cultured myocytes.  82:375-385. 1998

Cyclic GMP-dependent protein kinase inhibits osteopontin and thrombospondin production in rat aortic smooth muscle cells.  82:139-146. 1998

Cross talk between angiotensin AT1 and α1-adrenergic receptors: Angiotensin II downregulates α(1a)-adrenergic receptor subtype mRNA and density in neonatal rat cardiac myocytes.  81:396-403. 1997

Anisotropic Activation Spread in Heart Cell Monolayers Assessed by High-Resolution Optical Mapping: Role of Tissue Discontinuities.  79:115-127. 1996

Functional and structural assessment of intercellular communication: Increased conduction velocity and enhanced connexin expression in dibutyryl cAMP-treated cultured cardiac myocytes.  79:174-183. 1996

Spatial changes in transmembrane potential during extracellular electrical shocks in cultured monolayers of neonatal rat ventricular myocytes.  79:676-690. 1996

23Na and 31P nuclear magnetic resonance studies of ischemia-induced ventricular fibrillation. Alterations of intracellular Na+ and cellular energy..  77:394-406. 1995

Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite.  77:335-341. 1995

Altered pulmonary microvascular reactivity to norepinephrine in canine pacing-induced heart failure..  75:347-356. 1994

Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate.  75:591-595. 1994

Cloning of the rat α(1C)-adrenergic receptor from cardiac myocytes: α(1C), α(1B), and α(1D) mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.  75:796-802. 1994

Coronary pressure-flow relation in left ventricular hypertrophy: Importance of changes in back pressure versus changes in minimum resistance.  72:579-587. 1993

Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes.  73:914-925. 1993

Kinetics of restitution of left ventricular relaxation.  70:29-38. 1992

Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.  69:1427-1449. 1991

Correlation between transmural high energy phosphate levels and myocardial blood flow in the presence of graded coronary stenosis.  67:660-673. 1990

Differences in myosin isoform expression in the subepicardial and subendocardial myocardium during cardiac hypertrophy in the rat.  66:1127-1132. 1990

Differences in the electrophysiological response to canine ventricular subendocardium and subepicardium to acetylcholine and isoproterenol. A direct effect of acetylcholine in ventricular myocardium.  67:615-627. 1990

Increased ischemic injury but decreased hypoxic injury in hypertrophied rat hearts.  67:948-959. 1990

Morphological development of the rat heart growing in oculo in the absence of hemodynamic work load.  66:84-102. 1990

Vagally induced block and delayed conduction as a mechanism for circus movement tachycardia in frog atria.  64:213-226. 1989

Vascular remodeling and improvement of coronary reserve after hydralazine treatment in spontaneously hypertensive rats.  64:1127-1136. 1989

Transient outward current prominent in canine ventricular epicardium but not endocardium.  62:116-126. 1988

Sympathetic innervation alters growth and intrinsic heart rate of fetal rat atria maturing in oculo.  59:534-544. 1986

Histamine H1 receptor antagonists inhibit autoregulation of renal blood flow in the dog.  54:527-535. 1984

Effect of acute hypoxia on the pulmonary conversion of angiotensin I to angiotensin II in dogs.  46:221-226. 1980

Autoregulatory responses of superficial nephrons and their association with sodium excretion during arterial pressure alterations in the dog.  41:487-496. 1977

Development of left ventricular hypertrophy in young spontaneously hypertensive rats after peripheral sympathectomy.  40:428-434. 1977

Relation of renal hemodynamics to metabolism of angiotensin II by the canine kidney.  41:283-287. 1977

Structural requirements for substrates and inhibitors of angiotensin I converting enzyme in vivo and in vitro.  34:19-26. 1974

Mechanism of renal handling of angiotensin II in the dog.  33:500-507. 1973

Substrate requirements for angiotensin I conversion in vivo and in vitro..  32:415-423. 1973

Mechanism of pulmonary conversion of angiotensin I to angiotensin II in the dog..  29:682-690. 1971

In-vivo and in-vitro conversion of angiotensin I to angiotensin II in dog blood..  26:591-599. 1970