Science Signaling

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Engineered il-10 variants elicit potent immunomodulatory effects at low ligand doses. 13. 2020

GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma. 13. 2020

Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration. 13. 2020

Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment. 12. 2019

Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. 12. 2019

Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against β-amyloid. 12. 2019

Dynamic DNA methylation regulates neuronal intrinsic membrane excitability. 9. 2016

Cancer: The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. 8. 2015

DNA methylation regulates neuronal glutamatergic synaptic scaling. 8. 2015

Science signaling podcast: 23 June 2015. 8. 2015

The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells 2014

The emergence of the conserved AAA+ ATPases pontin and reptin on the signaling landscape. 6. 2013

Akt phosphorylates the transcriptional repressor Bmi1 to block its effects on the tumor-suppressing Ink4a-Arf locus. 5. 2012

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos). 4. 2011

International Standard Serial Number (issn)

1945-0877

Electronic International Standard Serial Number (eissn)

1937-9145