Overview
Publication Venue For
Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry.
15.
2019
Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression.
15.
2019
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
15.
2019
De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay.
14.
2018
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
14.
2018
MYT1L mutations cause intellectual disability and variable obesity by dysregulating gene expression and development of the neuroendocrine hypothalamus.
13.
2017
The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas.
13.
2017
Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African ancestry anthropometry genetics consortium.
13.
2017
GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.
13.
2017
Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.
12.
2016
Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology.
12.
2016
Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.
12.
2016
Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.
12.
2016
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects..
12:e1005963.
2016
A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4.
12.
2016
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap..
11:e1005155.
2015
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension.
11.
2015
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus.
11.
2015
Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGS.
11.
2015
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes.
10.
2014
MicroRNAs Located in the Hox Gene Clusters Are Implicated in Huntington's Disease Pathogenesis.
10.
2014
ATRA-Induced Cellular Differentiation and CD38 Expression Inhibits Acquisition of BCR-ABL Mutations for CML Acquired Resistance.
10.
2014
Deletion of a Conserved cis-Element in the Ifng Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription.
10.
2014
Glutamate Receptor Gene GRIN2A, Coffee, and Parkinson Disease.
10.
2014
Retinoic Acid-Related Orphan Receptor γ (RORγ): A Novel Participant in the Diurnal Regulation of Hepatic Gluconeogenesis and Insulin Sensitivity.
10.
2014
Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression.
9.
2013
VAPB/ALS8 MSP Ligands Regulate Striated Muscle Energy Metabolism Critical for Adult Survival in Caenorhabditis elegans.
9.
2013
Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci.
9.
2013
Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations.
9.
2013
A Dual Role for SOX10 in the Maintenance of the Postnatal Melanocyte Lineage and the Differentiation of Melanocyte Stem Cell Progenitors.
9.
2013
Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus TNFSF4.
9.
2013
Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid Arthritis.
9.
2013
Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production.
9.
2013
A Heterogeneous Mixture of F-Series Prostaglandins Promotes Sperm Guidance in the Caenorhabditis elegans Reproductive Tract.
9.
2013
A Systematic Mapping Approach of 16q12.2/FTO and BMI in More Than 20,000 African Americans Narrows in on the Underlying Functional Variation: Results from the Population Architecture using Genomics and Epidemiology (PAGE) Study.
9.
2013
MicroRNA-3148 Modulates Allelic Expression of Toll-Like Receptor 7 Variant Associated with Systemic Lupus Erythematosus.
9.
2013
Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic Domain.
8.
2012
Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program.
8.
2012
Rates of Gyrase Supercoiling and Transcription Elongation Control Supercoil Density in a Bacterial Chromosome.
8.
2012
The chicken frizzle feather is due to an α-Keratin (KRT75) mutation that causes a defective rachis.
8.
2012
Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation.
8.
2012
Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis.
8.
2012
Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasis.
8.
2012
Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context.
8.
2012
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals.
8.
2012
Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database.
8.
2012
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
8.
2012
A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.
7.
2011
Hierarchical generalized linear models for multiple groups of rare and common variants: Jointly estimating group and Individual-Variant effects.
7.
2011
The NF1 gene contains hotspots for L1 endonuclease-dependent De Novo insertion.
7.
2011
Positional cloning of a type 2 diabetes quantitative trait locus; Tomosyn-2, a negative regulator of insulin secretion.
7.
2011
Analysis of dna methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.
7.
2011
Gamma-tubulin is required for bipolar spindle assembly and for proper kinetochore microtubule attachments during prometaphase i in drosophila oocytes.
7.
2011
Genome-wide gene-environment study identifies glutamate receptor gene grin2a as a parkinson's disease modifier gene via interaction with coffee.
7.
2011
Recurrent chromosome 16p13.1 duplications are a risk factor for aortic dissections.
7.
2011
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
7.
2011
Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility..
7:e1002079.
2011
The exocyst protein sec10 interacts with polycystin-2 and knockdown causes PKD-phenotypes.
7.
2011
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production..
7:e1001323.
2011
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.
7.
2011
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for crohn's disease and celiac disease.
7.
2011
CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19-igf2 imprinting control region in prospermatogonia.
6.
2010
Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.
6:1-12.
2010
A microarray-based genetic screen for yeast chronological aging factors.
6.
2010
Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.
6:1-11.
2010
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
5.
2009
Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.
5.
2009
The role of geography in human adaptation.
5.
2009
A genome-wide association study of pulmonary function measures in the framingham heart study.
5.
2009
An african ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in african americans.
5.
2009
Retraction: an African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans..
5.
2009
The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.
5.
2009
Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development.
4:e1000259-e1000259.
2008
Evaluating statistical methods using plasmode data sets in the age of massive public databases: An illustration using false discovery rates.
4.
2008
The ets-related transcription factor GABP directs bidirectional transcription.
3:2247-2255.
2007
A Dinucleotide Deletion in CD24 Confers Protection against Autoimmune Diseases.
3:e49-e49.
2007
Identification of two independent risk factors for lupus within the MHC in United Kingdom families.
3:2109-2121.
2007
Regional admixture mapping and structured association testing: Conceptual unification and an extensible general linear model.
2:1254-1264.
2006
Regional admixture mapping and structured association testing: conceptual unification and an extensible general linear model..
2.
2006
Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice.
1:0205-0212.
2005
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function..
1.
2005
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
1:0480-0488.
2005
Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants.
8:e1002707-e1002707.
