Biochemical Pharmacology

Journal

Publication Venue For

  • An engineered heterodimeric model to investigate SULT1B1 dependence on intersubunit communication.  115:123-133. 2016
  • Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.  109:14-26. 2016
  • Farnesol activates the intrinsic pathway of apoptosis and the ATF4-ATF3-CHOP cascade of ER stress in human T lymphoblastic leukemia Molt4 cells.  97:256-268. 2015
  • Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells.  85:1066-1076. 2013
  • Nicotine signaling and progression of chronic kidney disease in smokers.  86:1215-1223. 2013
  • Rat CYP24A1 acts on 20-hydroxyvitamin D3 producing hydroxylated products with increased biological activity.  84:1696-1704. 2012
  • Opioidergic mechanisms underlying the actions of Vitex agnus-castus L..  81:170-177. 2011
  • Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer.  80:1833-1843. 2010
  • Tocotrienols, the vitamin E of the 21st century: Its potential against cancer and other chronic diseases.  80:1613-1631. 2010
  • Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities.  80:955-963. 2010
  • Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake.  80:1021-1032. 2010
  • 7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities.  76:958-966. 2008
  • Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.  73:1558-1572. 2007
  • Regulation of α2AR trafficking and signaling by interacting proteins.  73:1135-1145. 2007
  • 6-Benzylthioinosine analogues: Promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es).  71:69-73. 2005
  • 6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: Activities and selective toxicities.  69:1409-1419. 2005
  • The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G.  66:733-737. 2003
  • DNA repair mechanisms involved in gemcitabine cytotoxicity and in the interaction between gemcitabine and cisplatin.  65:275-282. 2003
  • Cellular glutathione and thiols metabolism.  64:1019-1026. 2002
  • Lysophosphatidylcholine as a ligand for immunoregulation.  64:161-167. 2002
  • Metabolism of 4'-thio-β-d-arabinofuranosylcytosine in CEM cells.  60:1925-1932. 2000
  • 5-Phenylthioacyclouridine: A potent and specific inhibitor of uridine phosphorylase.  60:851-856. 2000
  • Effect of administration of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on the anti-tumor efficacy of 5-fluoro-2'-deoxyuridine against murine colon tumor C26-10.  60:687-692. 2000
  • Modulation of 5-fluorouracil host toxicity by 5- (benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2',3',5'-tri-O-acetyluridine, a prodrug of uridine.  60:427-431. 2000
  • Attenuation of interleukin-8 production by inhibiting nuclear factor-κB translocation using decoy oligonucleotides.  59:605-613. 2000
  • Pyrimidine nucleobase ligands of orotate phosphoribosyltransferase from toxoplasma gondii.  58:1457-1466. 1999
  • Metabolism and metabolic actions of 6-methylpurine and 2-fluoroadenine in human cells.  55:1673-1681. 1998
  • Adaptation to oxidative stress: Quinone-mediated protection of signaling in rat lung epithelial L2 cells.  53:987-993. 1997
  • 5-(m-Benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2′,3′,5′-tri-O-acetyluridine, a prodrug of uridine, as modulators of plasma uridine concentration: Implications for chemotherapy.  51:1601-1611. 1996
  • Effects of modifications in the pentose moiety and conformational changes on the binding of nucleoside ligands to uridine phosphorylase from Toxoplasma gondii.  51:1687-1700. 1996
  • Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyltransferase from Toxoplasma gondii.  50:1685-1693. 1995
  • Sensitive method for quantitation of angiotensin-converting enzyme (ACE) activity in tissue.  50:1445-1450. 1995
  • Effects of tenidap on superoxide-generating enzymes. Non-competitive inhibition of xanthine oxidase.  50:811-814. 1995
  • Metabolism and metabolic actions of 4′-thiothymidine in L1210 cells.  50:687-695. 1995
  • Structure-activity relationship for the binding of nucleoside ligands to adenosine kinase from Toxoplasma gondii.  49:1501-1512. 1995
  • Effects of C-methylated carnitine analogs on rates of mitochondrial fatty acid oxidation.  46:1671-1673. 1993
  • 5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase.  46:1273-1283. 1993
  • The role of α-tocopherol as a peroxyl radical scavenger in human low density lipoprotein.  45:2195-2201. 1993
  • Circadian rhythm of orotate phosphoribosyltransferase, pyrimidine nucleoside phosphorylases and dihydrouracil dehydrogenase in mouse liver. Possible relevance to chemotherapy with 5-fluoropyrimidines.  45:667-673. 1993
  • Irreversible inhibition of S-adenosylmethionine decarboxylase of trypanosoma bru cei bru cei by S-adenosylmethionine analogues.  44:905-911. 1992
  • Inhibitory effect of eugenol on non-enzymatic lipid peroxidation in rat liver mitochondria.  43:2393-2400. 1992
  • Isoforms of nitric oxide synthase Characterization and purification from different cell types.  42:1849-1857. 1991
  • Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Possible relevance to regional chemotherapy.  41:1887-1893. 1991
  • Efficacy of combination therapy with tubercidin and nitrobenzylthioinosine 5'- monophosphate against chronic and advanced stages of schistosomiasis.  41:815-820. 1991
  • Circadian rhythm of hepatic uridine phosphorylase activity and plasma concentration of uridine in mice.  40:2479-2485. 1990
  • 2-Fluoro-β-alanine, a previously unrecognized substrate for bile acid coenzyme A:Amino acid:N-acyltransferase from human liver.  40:1241-1246. 1990
  • A method for the comparative assessment of antioxidants as peroxyl radical scavengers.  38:1465-1469. 1989
  • Structure-activity relationship of ligands of dihydrouracil dehydrogenase from mouse liver.  38:1471-1480. 1989
  • Treatment of schistosomiasis by purine nucleoside analogues in combination with nucleoside transport inhibitors.  36:3815-3821. 1987
  • New analogues of benzylacyclouridines, specific and potent inhibitors of uridine phosphorylase from human and mouse livers.  36:2195-2201. 1987
  • 5′-Deoxy-5′-methylthioadenosine phosphorylase-IV. Biological activity of 2-fluoroadenine-substituted 5′-deoxy-5′ -methylthioadenosine analogs.  36:1881-1893. 1987
  • Metabolism of adenosine analogues by Schistosoma mansoni and the effect of nucleoside transport inhibitors.  36:1099-1106. 1987
  • Inhibition of uridine phosphorylase from Escherichia coli by benzylacyclouridines.  35:3853-3855. 1986
  • Combination therapy of Schistosoma japonicum by tubercidin and nitrobenzylthioinosine 5′-monophosphate.  34:3921-3923. 1985
  • Metabolism of carbidopa to alphamethyldopamine and alphamethylnorepinephrine in rats.  34:3623-3626. 1985
  • Nucleotidase activities of human peripheral lymphocytes.  34:3061-3070. 1985
  • Structure-activity relationship of pyrimidine base analogs as ligands of orotate phosphoribosyltransferase.  33:2383-2395. 1984
  • Effect of hypoxia on the conversion of angiotensin I to II in cultured porcine pulmonary endothelial cells.  32:1201-1205. 1983
  • Structure-activity relationship of ligands of the pyrimidine nucleoside phosphorylases.  32:399-415. 1983
  • Acetazolamide inhibition of renal γ-glutamyl transpeptidase.  31:3347-3352. 1982
  • 5-Benzylacyclouridine and 5-benzyloxybenzylacyclouridine, potent inhibitors of uridine phosphorylase.  31:1857-1861. 1982
  • Effect of hypoxia on the conversion of angiotensin I to II in the isolated perfused rat lung.  31:1375-1379. 1982
  • Pyrimidine acyclonucleosides, inhibitors of uridine phosphorylase.  30:2097-2101. 1981
  • In vivo and in vitro conversion of des-1-Asp angiotensin I to angiotensin III.  27:2871-2877. 1978
  • Inhibition of gastric K+ ATPase by phenylbutazone and indomethacin.  26:1241-1245. 1977
  • International Standard Serial Number (issn)

  • 0006-2952
  • Electronic International Standard Serial Number (eissn)

  • 1873-2968